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Clinical trials for Tacrolimus

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43861   clinical trials with a EudraCT protocol, of which   7284   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    435 result(s) found for: Tacrolimus. Displaying page 1 of 22.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2021-006481-21 Sponsor Protocol Number: 79916 Start Date*: 2022-09-08
    Sponsor Name:Erasmus MC - Sophia Kinderziekenhuis
    Full Title: Personalized tacrolimus treatment for pediatric kidney transplant recipients by using a dosing algorithm and a once-daily tacrolimus formulation
    Medical condition: Renal transplant recipients
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004314-29 Sponsor Protocol Number: CCD-06235AA1-01 Start Date*: 2015-02-27
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: MULTICENTRE, OPEN LABEL, RANDOMIZED, TWO-ARM, PARALLEL-GROUP STUDY TO ASSESS EFFICACY AND SAFETY OF ENVARSUS® COMPARED WITH TACROLIMUS USED AS PER CURRENT CLINICAL PRACTICE IN THE INITIAL MAINTENAN...
    Medical condition: ESRD (end stage renal disease)
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) AT (Completed) ES (Completed) DE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002519-17 Sponsor Protocol Number: DDD16JRtac Start Date*: 2016-09-12
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: Supersaturation and precipitation of tacrolimus in the stomach of healthy volunteers
    Medical condition: Healthy human volunteers , investigation of the drug's supersaturation behaviour in the stomach
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001681-24 Sponsor Protocol Number: TAC01 Start Date*: 2017-09-27
    Sponsor Name:Erasmus MC
    Full Title: Avoiding tacrolimus under- and overexposure by using a new dosing algorithm for pediatric renal transplant recipients
    Medical condition: kidney transplantation
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-017600-89 Sponsor Protocol Number: FC/hulp003 Start Date*: 2010-06-24
    Sponsor Name:Asociación para la investigación de Nefrología Infantil
    Full Title: Ensayo intrapaciente de biodisponibilidad relativa de dos formulaciones de tacrolimus: Prograf (comprimidos de liberación normal) y Advagraf (comprimidos de liberación sostenida) en niños trasplant...
    Medical condition: Transplante renal
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001290-24 Sponsor Protocol Number: NFAT Start Date*: 2018-12-11
    Sponsor Name:Medical University of Graz
    Full Title: NFAT-regulated gene expression after tacrolimus
    Medical condition: Immunosuppression after liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021428 - Immune system disorders 10062016 Immunosuppression PT
    21.0 100000004865 10024716 Liver transplantation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001909-24 Sponsor Protocol Number: Spartacus/007 Start Date*: 2012-10-24
    Sponsor Name:University Medical Center Utrecht
    Full Title: A Multi Center, Prospective, Observational, Open-label, Pharmacokinetic Study of Tacrolimus in Heart and Lung Transplantation Patients during the First Days after Transplantation
    Medical condition: Heart and lung transplantation, first days after transplantation
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004848 10053349 Pharmacokinetic study LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-000011-25 Sponsor Protocol Number: Mozaiek3 Start Date*: 2018-10-11
    Sponsor Name:Erasmus MC
    Full Title: Avoiding tacrolimus under- and overexposure by using a new dosing algorithm for renal transplant recipients
    Medical condition: kidney transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002425-35 Sponsor Protocol Number: NL2014-002425-35/SpartacusBrindisi Start Date*: 2015-07-20
    Sponsor Name:National Poisons Information Center, University Medical Center Utrecht
    Full Title: A Single Centered, Prospective, Open-labeled, Pharmacokinetic Pilot Study of Tacrolimus Administration via Rectiole
    Medical condition: Heart and lung transplantation patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019398-14 Sponsor Protocol Number: RB02 Start Date*: 2010-10-07
    Sponsor Name:Erasmus Medical Center
    Full Title: IMPROVEMENT OF RENAL FUNCTION BY CONVERSION OF TACROLIMUS TO EVEROLIMUS 3 MONTHS AFTER KIDNEY TRANSPLANTATION
    Medical condition: Kidney Transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004043-23 Sponsor Protocol Number: CoFu-01 Start Date*: 2020-07-23
    Sponsor Name:University Hospital Schleswig-Holstein (UKSH)
    Full Title: Cognitive function after liver transplantation comparing Tacrolimus formulations
    Medical condition: Immunosuppression post liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004865 10024716 Liver transplantation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001101-22 Sponsor Protocol Number: PURE Start Date*: 2021-08-23
    Sponsor Name:Amsterdam UMC
    Full Title: Study to evaluate the efficacy and side effects of Envarsus in patients who had a kidney transplantation
    Medical condition: Kidney transplant immunosupression for patients with CYP3A5*1 gene variance
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021428 - Immune system disorders 10023439 Kidney transplant rejection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003595-13 Sponsor Protocol Number: 17CS079 Start Date*: 2019-10-01
    Sponsor Name:Research and Innovation, Nottingham University Hospital
    Full Title: Pilot dose conversion study of extended release tacrolimus, Envarsus from standard twice daily tacrolimus in paediatric renal transplant recipients.
    Medical condition: Kidney transplantation - prevention of rejection.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021428 - Immune system disorders 10023439 Kidney transplant rejection PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2015-002465-28 Sponsor Protocol Number: ICANMINI Start Date*: 2016-02-19
    Sponsor Name:Klinikum der Universität München
    Full Title: Anti-donor alloreactivity-guided CNI minimization versus unguided standard triple therapy in living-donor kidney transplantation
    Medical condition: Renal transplantation
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003710-13 Sponsor Protocol Number: Pro-Tac Start Date*: Information not available in EudraCT
    Sponsor Name:University Hospital Essen
    Full Title: A multi-center interventional study to assess pharmacokinetics, effectiveness and tolerability of prolonged-release Tacrolimus after Paediatric Kidney Transplantation
    Medical condition: Caucasian paediatric kidney transplant recipients
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004467-29 Sponsor Protocol Number: Start Date*: 2005-07-27
    Sponsor Name:Craigavon Area Hospital Group Trust
    Full Title: An open label pilot study to evaluate the efficacy and safety of topical tacrolimus 0l1% (Protopic) in the treatment of varicose eczema
    Medical condition: Varicose eczema
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000306-46 Sponsor Protocol Number: FG-506E-11-03 Start Date*: 2004-07-16
    Sponsor Name:FUJISAWA
    Full Title: A multicentre, 1:1 randomised, double blind, two arm parallel group study to evaluate and compare the efficacy and safety of modified release tacrolimus FK506E (MR4) versus tacrolimus FK506 in comb...
    Medical condition: Liver transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) FI (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-001854-24 Sponsor Protocol Number: NL67751.078.18 Start Date*: 2019-08-07
    Sponsor Name:Erasmus Medical Center
    Full Title: Long-term outcomes in immunologically low-risk kidney transplant recipients using tacrolimus. Extension study of: Tacrolimus monotherapy in immunologically low-risk kidney transplant recipients: a ...
    Medical condition: kidney transplantation vaccination responses
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001076-22 Sponsor Protocol Number: 03-0-160 Start Date*: 2015-04-13
    Sponsor Name:Fujisawa Healthcare, Inc.
    Full Title: A PHASE II, OPEN-LABEL, MULTI-CENTER STUDY TO ASSESS THE PHARMACOKINETICS, LONG-TERM SAFETY AND TOLERABILITY OF TACROLIMUS IN STABLE PEDIATRIC LIVER TRANSPLANT PATIENTS CONVERTED FROM A PROGRAF® BA...
    Medical condition: Liver transplant rejection
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10050434 Prophylaxis against liver transplant rejection LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-002097-13 Sponsor Protocol Number: SI-05-RG-45 Start Date*: 2017-05-15
    Sponsor Name:Department of Cardiology, University Medical Centre Ljubljana
    Full Title: Comparison of modified-release and standard tacrolimus immunosuppression regimens in heart transplant recipients
    Medical condition: Tacrolimus is a potent immunosuppressant agent widely used for the prevention and treatment of rejection in heart transplant recipients. While tacrolimus is typically administered in two divided do...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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