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Clinical trials for Tegafur

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    21 result(s) found for: Tegafur. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-003767-39 Sponsor Protocol Number: 955/08 Start Date*: 2008-09-14
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Concomitant radiochemotherapy with Tegafur and Mitomycin in locally advanced anal canal cancer: Dose Escalation Study.
    Medical condition: locally advanced squamous anal canal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041840 Squamous cell carcinoma of the anus stage unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004212-23 Sponsor Protocol Number: DMM1-TGF-03 Start Date*: 2005-02-03
    Sponsor Name:Unidad Integral de Investigación en Oncología, S.L.
    Full Title: Randomized study with oral tegafur versus capecitabina in the treatment of advanced politreated breast cancer and refractory, resistant or in progression to the standard chemotherapeutic treatment
    Medical condition: breast cancer
    Disease: Version SOC Term Classification Code Term Level
    10027475
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001806-40 Sponsor Protocol Number: TO-TAS-114-201 Start Date*: 2016-11-03
    Sponsor Name:Taiho Oncology, Inc.
    Full Title: A Randomized, Open-Label, Multi-Center, International Phase 2 Study of TAS-114 in Combination with S-1 in Patients with Advanced or Metastatic Non-Small Cell Lung Cancer
    Medical condition: Male and female patients age 18 years or older with histologically or cytologically confirmed advanced or metastatic NSCLC for whom standard therapy no longer exists
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2005-003272-38 Sponsor Protocol Number: TPU-S1204 Start Date*: Information not available in EudraCT
    Sponsor Name:Taiho Pharma USA, Inc
    Full Title: AN OPEN-LABEL, NON-RANDOMIZED, MULTICENTER, TWO-STAGE, PHASE 2 STUDY OF S-1 IN CHEMOTHERAPY-NAIVE PATIENTS WITH LOCALLY ADVANCED OR METASTATIC PANCREATIC CANCER.
    Medical condition: Pancreatic cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000065-38 Sponsor Protocol Number: ASL607LIOM01 COMET-GI Start Date*: 2007-02-28
    Sponsor Name:AZIENDA USL 6 LIVORNO ZONA LIVORNESE
    Full Title: METRONOMIC CHEMOTHERAPY WITH URACIL/TEGAFUR (UFT), CYCLOPHOSPHAMIDE (CTX) AND CELECOXIB IN PRETREATED PATIENTS WITH ADVANCED GASTROINTESTINAL MALIGNANCIES: A PILOT CLINICAL STUDY WITH PHARMACOKINET...
    Medical condition: PATIENTS WITH ADVANCED GASTROINTESTINAL MALIGNANCIES
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061174 Gastrointestinal neoplasm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001852-38 Sponsor Protocol Number: EFC10203 Start Date*: 2007-12-21
    Sponsor Name:sanofi-aventis recherche & developpement
    Full Title: A Multicenter, Open-Label, Randomized Study Comparing the Efficacy and Safety of S-1 as a Single Agent at 30 mg/m2 BID versus 5-FU Bolus Infusion for the Treatment of Patients with Metastatic Panc...
    Medical condition: Advanced Pancreatic Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033609 Pancreatic carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) HU (Completed) SE (Completed) GR (Completed) DK (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002742-37 Sponsor Protocol Number: AIO-YMO-0111 Start Date*: 2014-08-12
    Sponsor Name:AIO-Studien-gGmbH
    Full Title: Randomized controlled trial of S-1 maintenance therapy in metastatic esophagogastric cancer
    Medical condition: metastatic esophagogastric cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) SE (Completed) ES (Ongoing) BE (Completed) FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006151-40 Sponsor Protocol Number: MITOUFT Start Date*: 2007-12-29
    Sponsor Name:AZIENDA OSPEDALIERA S. LUIGI GONZAGA
    Full Title: UFT/LEUCOVORIN AND MITOMYCIN C IN THE TREATMENT OF METASTATIC COLORECTAL CANCER OXALIPLATIN AND IRINOTECAN RESISTANT
    Medical condition: PATIENTS WITH METASTATIC COLON-RECTAL CANCER
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052358 Colorectal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003976-11 Sponsor Protocol Number: HSG-1-13 Start Date*: 2014-01-24
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Effects of S-1 and capecitabine in combination with oxaliplatin on the coronary artery blood flow in patients metastatic gastrointestinal tract adenocarcinoma
    Medical condition: Metastatic gastrointestinal tract adenocarcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002255-15 Sponsor Protocol Number: DPDIMP#1 Start Date*: 2019-06-19
    Sponsor Name:Helsinki University Hospital
    Full Title: No official English language name
    Medical condition: Suolistosyöpä, rintasyöpä
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-005282-12 Sponsor Protocol Number: Start Date*: 2013-05-14
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. Research and Development NHS Lothian
    Full Title: TOFFEE Trial Toxicity OF Fluoropyrimidines: A comparative study of the cardiotoxicity of capEcitabine and tEysuno
    Medical condition: All gastrointestinal and hepatobiliary cancers including colorectal cancer, cancer of unknown primary, pancreatic cancer, stomach cancer and oesophageal cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004710-16 Sponsor Protocol Number: TPU-S1301 Start Date*: 2005-07-01
    Sponsor Name:Taiho Pharma USA, Inc.
    Full Title: An open label, multicenter, randomized, phase 3 study of S-1 in combination with cisplatin compared against 5-FU in combination with cisplatin in patients with advanced gastric cancer previously un...
    Medical condition: Advanced gastric cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) CZ (Completed) DE (Completed) EE (Completed) BE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016019-39 Sponsor Protocol Number: TPU-S1303 Start Date*: 2011-02-14
    Sponsor Name:Taiho Oncology, Inc.
    Full Title: AN OPEN-LABEL, MULTICENTER, RANDOMIZED, PHASE 3 STUDY OF S-1 AND CISPLATIN COMPARED WITH 5-FU AND CISPLATIN IN PATIENTS WITH METASTATIC DIFFUSE GASTRIC CANCER PREVIOUSLY UNTREATED WITH CHEMOTHERAPY
    Medical condition: Metastatic Diffuse Gastric Cancer
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10063916 Metastatic gastric cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) HU (Completed) GB (Completed) ES (Completed) PT (Completed) EE (Completed) IT (Prematurely Ended) BG (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000685-36 Sponsor Protocol Number: EMR 200025 – 001 Start Date*: 2006-11-29
    Sponsor Name:Merck KGaA
    Full Title: A randomized, open-label phase II study evaluating the efficacy and safety of FOLFOX-4 plus cetuximab versus UFOX plus cetuximab as first-line therapy in subjects with metastatic colorectal cancer
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) FR (Completed) BE (Completed) GR (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003325-41 Sponsor Protocol Number: 668353 Start Date*: 2017-06-09
    Sponsor Name:Leiden University Medical Center
    Full Title: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions
    Medical condition: Adverse drug reactions
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000394-39 Sponsor Protocol Number: KFEAC14.01 Start Date*: 2014-05-05
    Sponsor Name:Odense University Hospital
    Full Title: Full dose S-1 monotherapy compared to reduced dose S-1/oxaliplatin combination therapy as first-line treatment for older patients with metastatic colorectal cancer
    Medical condition: Treatment of older (≥ 70 years) patients with metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed) NO (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2017-004675-31 Sponsor Protocol Number: AMCmedonc17-010 Start Date*: 2019-11-13
    Sponsor Name:Academic Medical Center
    Full Title: A randomized Phase II study of second line treatment with liposomal irinotecan and S1 versus liposomal irinotecan and 5-fluorouracil in patients with metastatic pancreatic cancer who failed on firs...
    Medical condition: pancreatic cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing) ES (Ongoing) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-001355-21 Sponsor Protocol Number: 01-2008 Start Date*: 2008-06-30
    Sponsor Name:I.T.M.O. - ITALIAN TRIALS IN MEDICAL ONCOLOGY
    Full Title: First Line UFT, OXALIPLATIN and ERBITUX combination (TEGAFOX-E) in Elderly (≥ 70 years) metastatic colorectal patients: a Phase II ITMO study.
    Medical condition: Metastatic adenocarcinoma of colon or rectum
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-001347-29 Sponsor Protocol Number: Start Date*: 2004-09-17
    Sponsor Name:Odense University Hospital
    Full Title: Treatment of patients with locally advanced rectal cancer. TEGAFOX (UFT/leukovorin og Oxaliplatin) before, during and after curatively intended radiotherapy. A Danish phase I/II trial
    Medical condition: Locally advanced non-resectable rectal cancer
    Disease: Version SOC Term Classification Code Term Level
    6.0 10038050 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003669-87 Sponsor Protocol Number: M14-064 Start Date*: 2018-03-19
    Sponsor Name:Abbvie Deutschland GmbH & Co. KG
    Full Title: Phase 2 Study Comparing Efficacy and Safety of ABT-165 and FOLFIRI vs Bevacizumab and FOLFIRI in Metastatic Colorectal Cancer Previously Treated with Fluoropyrimidine/Oxaliplatin and Bevacizumab
    Medical condition: metastatic adenocarcinoma of the colon or rectum previously treated with a regimen containing fluoropyrimidine/oxaliplatin and bevacizumab
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) ES (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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