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Clinical trials for Thrombolysis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    112 result(s) found for: Thrombolysis. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2013-001558-87 Sponsor Protocol Number: UBS-HG Start Date*: 2014-02-24
    Sponsor Name:Karolinska University Hospital
    Full Title: Safety of normalising slightly elevated plasma glucose by Exenatide in acute ischemic stroke patients treated with intravenous thrombolysis: a pilot study
    Medical condition: Patients with acute ischemic stroke, treated with intravenous thrombolysis treatment according to the European regulatory criteria
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-000939-31 Sponsor Protocol Number: JDS_2021_5 Start Date*: 2021-11-02
    Sponsor Name:Hôpital Fondation A. de Rothschild / Service de recherche clinique
    Full Title: Efficacy of dornase alfa (Pulmozyme®) on arterial recanalization in post-thrombectomy angiography in patients managed for ischemic stroke by thrombolysis and eligible for thrombectomy: a monocentri...
    Medical condition: cerebral thrombectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-006829-13 Sponsor Protocol Number: 2005B118 Start Date*: 2008-02-19
    Sponsor Name:Netherlands Heart Foundation
    Full Title: Antiplatelet therapy in combination with Recombinant t-PA Thrombolysis in Ischemic Stroke
    Medical condition: Patients with ischemic stroke More specific patients with ischemic stroke treated with rt-PA thrombolysis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000323-41 Sponsor Protocol Number: NOR-SASS Start Date*: 2012-11-19
    Sponsor Name:Helse Bergen, Haukeland University Hospital
    Full Title: Randomised Trial of Contrast-enhanced Sonothrombolysis in acute ischaemic stroke
    Medical condition: All patients found eligible for thrombolysis may enter the thrombolysis-arm (NOR-SASS I), all patients with contraindications to thrombolysis within the 4 ½ hour time window may enter the no-throm...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002161-27 Sponsor Protocol Number: DUETII01 Start Date*: 2016-04-15
    Sponsor Name:Sint Antonius Hospital
    Full Title: Dutch randomized trial comparing Ultrasound-accElerated Thrombolysis with standard dose Urokinase versus half dose Urokinase for thrombo-embolic infra-inguinal arterial disease (DUET II)
    Medical condition: Acute thrombo-embolic occlusion of one of the infra-inguinal arteries
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000075-85 Sponsor Protocol Number: I-StrokeII2016 Start Date*: 2018-06-19
    Sponsor Name:Karolinska Institutet
    Full Title: A phase 3, randomised, double-blind, placebo-controlled, parallel-arm efficacy trial of Imatinib in acute ischaemic stroke
    Medical condition: Patients with acute ischaemic stroke and an imaging scan excluding any intracranial haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    22.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    22.1 10029205 - Nervous system disorders 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-003469-10 Sponsor Protocol Number: MUST14 Start Date*: 2015-08-05
    Sponsor Name:VU University Medical Center
    Full Title: The application of contrast-enhanced ultrasound to facilitate thrombolysis in patients with acute peripheral arterial occlusions.
    Medical condition: Acute peripheral arterial occlusions. Acute peripheral arterial occlusive disease can be caused by a blood clot blocking an artery in an arm or leg. This is an emergency situation that can result i...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019014-25 Sponsor Protocol Number: Istrokepilot Start Date*: 2010-07-27
    Sponsor Name:Karolinska University Hospital
    Full Title: A PROSPECTIVE, RANDOMISED, OPEN, BLINDED EVALUATION, ASCENDING-DOSE, PILOT TRIAL OF IMATINIB IN ACUTE ISCHAEMIC STROKE (I-STROKE/pilot)
    Medical condition: Acute ischaemic stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003474-86 Sponsor Protocol Number: NCT0023595 Start Date*: 2011-12-12
    Sponsor Name:Myron D. Ginsberg
    Full Title: Albumin in Acute Stroke (ALIAS) Trial-Part 2: A Phase III Randomized Multicenter Clinical Trial of High-Dose Human Albumin Therapy for Neuroprotection in Acute Ischemic Stroke
    Medical condition: Acute Ischemic Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002760-41 Sponsor Protocol Number: CL2-RTCCAR-001 Start Date*: 2017-09-18
    Sponsor Name:institute de Recherches Internacionales Servier (promotor internacional)
    Full Title: Assessment of Active Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa) plasma kinetics in Patients at acute stage of Ischemic Stroke: Prospective, Multicentre, Open, Non-randomised, Biomarker Study
    Medical condition: Acute Ischemic Stroke
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000013700 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-002061-22 Sponsor Protocol Number: RC17_0061 Start Date*: 2017-09-12
    Sponsor Name:CHU de Nantes
    Full Title: A phase III randomized, blind, double dummy, multicenter study assessing the efficacy and safety of IV thrombolysis (alteplase) in patients with acute central retinal artery occlusion
    Medical condition: acute central retinal artery occlusion
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10043568 Thrombolysis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004082-25 Sponsor Protocol Number: D5130C00137 Start Date*: 2015-03-27
    Sponsor Name:Hellenic Cardiovascular Research Society
    Full Title: A multicenter, prospective, randomized, open label, blinded endpoint, active-comparator trial to assess the MIcrovascular integrity and left ventricular function Recovery after clopidogrel or Ticag...
    Medical condition: Patients with Myocardial Infarction with ST-segment elevation (STEMI) undergoing thrombolysis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004486-42 Sponsor Protocol Number: CaVenT Start Date*: 2006-01-03
    Sponsor Name:Eastern Norway Regional Health Authority [...]
    1. Eastern Norway Regional Health Authority
    2. Ullevaal University Hospital
    Full Title: Catheter-directed Venous Thrombolysis (CaVenT) in Acute Iliofemoral Vein Thrombosis - an open Randomized, Controlled, Clinical Trial
    Medical condition: Acute ilio-femoral vein thrombosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-005075-91 Sponsor Protocol Number: STRATIFY-1 Start Date*: 2018-08-30
    Sponsor Name:Copenhagen University Hospital Rigshospitalet
    Full Title: LOW DOSE THROMBOLYSIS, ULTRASOUND ASSISTED THROMBOLYSIS OR HEPARIN FOR INTERMEDIATE HIGH RISK PULMONARY EMBOLISM
    Medical condition: Acute Pulmonary Embolism, intermediate high risk (visible impact on right ventricular structure and function, and biochemical markers og myocardial damage according to the European Society of Cardi...
    Disease: Version SOC Term Classification Code Term Level
    21.0 10038738 - Respiratory, thoracic and mediastinal disorders 10037377 Pulmonary embolism PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002447-81 Sponsor Protocol Number: 050003 Start Date*: 2007-04-12
    Sponsor Name:Talecris Biotherapeutics, Inc
    Full Title: A Sequential Phase I/II Dose Escalation and Dose Selection Safety Study of Regional Intra-thrombus Plasmin (Human) Infusion In Acute Lower Extremity Native Artery or Bypass Graft Occlusion
    Medical condition: Acute Lower Extremity Native Artery or Bypass Graft Occlusion
    Disease: Version SOC Term Classification Code Term Level
    8.1 10043628 Thrombosis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) CZ (Completed) BG (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005906-32 Sponsor Protocol Number: WAKE-UP Start Date*: 2012-09-24
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Efficacy and safety of MRI-based thrombolysis in wake-up stroke: a randomised, double-blind, placebo-controlled trial
    Medical condition: Patients with acute ischemic stroke proven by MRI and unknown time from symptom onset which otherwise fulfil the approval criteria for intravenous thrombolysis in acute stroke
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed) GB (Completed) DK (Completed) ES (Completed) NL (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-000238-16 Sponsor Protocol Number: APD791-202 Start Date*: 2021-05-07
    Sponsor Name:Arena Pharmaceuticals, Inc.
    Full Title: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Effect on Microvascular Obstruction of Temanogrel in Subjects Undergoing Percutane...
    Medical condition: Microvascular Obstruction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004866 10079682 Microvascular occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001599-13 Sponsor Protocol Number: TNKCAT Start Date*: 2021-08-13
    Sponsor Name:Hospital Vall Hebron
    Full Title: Tenecteplase Compared to Alteplase for Large Vesel Oclusion patients before Thrombectomy
    Medical condition: Acute Ischaemic Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002075-10 Sponsor Protocol Number: GN14NE598 Start Date*: 2016-09-21
    Sponsor Name:NHS Greater Glasgow & Clyde [...]
    1. NHS Greater Glasgow & Clyde
    2. University of Glasgow
    Full Title: Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis 2
    Medical condition: Acute ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-005545-12 Sponsor Protocol Number: Start Date*: 2012-03-02
    Sponsor Name:University of Leicester
    Full Title: Enhanced Control of Hypertension and Thrombolysis Stroke Trial
    Medical condition: Acute Ischaemic Stroke
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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