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Clinical trials for Thyroxine

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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    67 result(s) found for: Thyroxine. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2014-000574-19 Sponsor Protocol Number: LT4RAIT Start Date*: 2014-03-24
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA DI PARMA
    Full Title: Experimental study for the evaluation of the effect of radioactive iodine therapy on free thyroxine circulating levels after oral administration of sodium levo-thyroxine in patients thyroidectomiz...
    Medical condition: patients thyroidectomized for differentiated thyroid cancer
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004863 10057242 Post surgical hypothyroidism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021228-89 Sponsor Protocol Number: CICO-10-01 Start Date*: 2011-04-22
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Effect of L-Thyroxine supplementation in the first weeks of life on long-term neurodevelopmental outcome in infants with transient hypothyroxinemia born at or less than 28 weeks’ gestation
    Medical condition: infants with transient hypothyroxinemia born at or less than 28 weeks’ gestation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10043816 Thyroxine decreased PT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005184-15 Sponsor Protocol Number: 05_ENDO_46 Start Date*: 2005-05-24
    Sponsor Name:Christie Hospital NHS Trust
    Full Title: Central Hypothyroidism and Adjusted Thyroxine dose Study (CHATS): impact of increasing free thyroxine levels in patients with hypopituitarism
    Medical condition: Central (secondary/tertiary) hypothyroidism (subclinical)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023918-30 Sponsor Protocol Number: SOMA-001-2010 Start Date*: 2011-03-16
    Sponsor Name:SOCIETA' ITALO BRITANNICA L. MANETTI - H.ROBERTS & C. PER AZIONI
    Full Title: Pilot clinical study on the systemic bioavailability of l-thyroxine in healthy female volunteers after four weeks of topical treatment with a new formulation based on l-thyroxine
    Medical condition: treatment of localized fat, accompanied by cellulite
    Disease: Version SOC Term Classification Code Term Level
    14.1 10040785 - Skin and subcutaneous tissue disorders 10065339 Cellulite LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003464-30 Sponsor Protocol Number: CTHS02 Start Date*: 2005-09-08
    Sponsor Name:Queen Mary, University of London
    Full Title: Double blind randomised cross-over trial to assess the value of screening an adult population for hypothyroidism
    Medical condition: Hypothyroidism. People with high thyroid stimulating hormone (TSH) serum level with normal or low free thyroxine.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001248-12 Sponsor Protocol Number: THYR69 Start Date*: 2015-10-30
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA MEYER
    Full Title: Randomized crossover trial for the evaluation of the possible effects in the intestine of two different pharmaceutical forms of L - Thyroxine in patients with primary acquired hypothyroidism
    Medical condition: Primary acquired hypothyroidism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10000559 Acquired hypothyroidism LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023509-37 Sponsor Protocol Number: IIT2010 Start Date*: 2011-06-29
    Sponsor Name:Institut für klinische Forschung und Entwicklung Berlin GmbH am St. Hedwig Krankenhaus
    Full Title: A prospective, randomized, single-blind, placebo-controlled, two-armed, phase IV study in patients with subclinical hypothyroidism treated over 52 weeks either with levothyroxine in adjusted dosing...
    Medical condition: Subclinical hypothyroidism
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005732-28 Sponsor Protocol Number: LE-9999-401-BE Start Date*: 2013-06-14
    Sponsor Name:Takeda Belgium
    Full Title: A multicentre, open-label switch study to investigate the necessity of dose adjustment after switching from L-Thyroxine Christiaens® to the new levothyroxine sodium test formulation in (near) total...
    Medical condition: Patient that underwent a near total thyroidectomy and therefore are compelled to take levothyroxine hormone substition therapy.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10043777 Thyroidectomy total LLT
    16.0 10014698 - Endocrine disorders 10021114 Hypothyroidism PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001369-28 Sponsor Protocol Number: 880 Start Date*: 2014-10-30
    Sponsor Name:Gateshead Health NHS Foundation Trust
    Full Title: THYRoxine in Acute Myocardial Infarction (ThyrAMI)
    Medical condition: Hypothyroidism and Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002614-36 Sponsor Protocol Number: 05ICHF/T407 Start Date*: 2007-04-20
    Sponsor Name:IBSA
    Full Title: Multicentre, controlled, randomised, open-label, cross-over clinical study of the efficacy and tolerability of L-thyroxine T4 soft capsules, in comparison to L-thyroxine tablets, in thyroidectomi...
    Medical condition: Substitutive and/or TSH suppressive therapy in thyroidectomized patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021117 Hypothyroidism postoperative LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-004876-20 Sponsor Protocol Number: GRAV12 Start Date*: 2012-11-13
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO
    Full Title: Study on the effectiveness of two different formulations of L-thyroxine compress and liquid oral solution) in pregnant patients affected with hypothyroidism.
    Medical condition: Hypothyroidism in pregnant patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10014698 Endocrine disorders SOC
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004136-38 Sponsor Protocol Number: LEVOSOFT_2016 Start Date*: 2018-07-26
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Full Title: PROSPECTIC, RANDOMIZED, NATIONAL MULTICENTRIC STUDY, FINALIZED TO ASSESS THE STABILITY OF TSH LEVELS IN THYROIDECTOMISED PATIENTS IN THERAPY WITH TWO FORMULATIONS OF LEVOTYROXIN (TABLETS AND SOFT-GEL)
    Medical condition: IATROGENIC HYPOTHYROIDISM IN THYROIDECTOMIZED PATIENTS
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10043741 Thyroid hypofunction disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005242-21 Sponsor Protocol Number: 07_ENDO_66 Start Date*: 2008-05-07
    Sponsor Name:THE CHRISTIE NHS FOUNDATION TRUST
    Full Title: A pilot study of replacement therapy with recombinant TSH in central hypothyroidism
    Medical condition: Central Hypothyroidism which is due to deficiency of TSH caused by the disease, surgery or radiotherapy of the pituitary gland.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003099-39 Sponsor Protocol Number: LWH0604 Start Date*: 2008-08-21
    Sponsor Name:Liverpool Women's NHS Foundation Trust Hospital
    Full Title: A Randomised Controlled Trial of Thyroxine in Preterm Infants Under 28 weeks' Gestation.
    Medical condition: Hypothyroidism is a condition where there is a lack of thyroid hormone in the body. Thyroid hormones are important for normal brain development and growth. Children who are born with low thyroid ho...
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001696-21 Sponsor Protocol Number: AOBS-2MED-TICO-2013 Start Date*: 2013-08-20
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: Prospective blinded study of the absorption of levothyroxine oral solution (Tirosint ® single-dose oral solution) in patients with hypothyroidism.
    Medical condition: Hypothyrodism
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001681-25 Sponsor Protocol Number: 23681 Start Date*: 2015-07-15
    Sponsor Name:Merck KGaA
    Full Title: An Open, Multicenter, Randomized, Controlled Trial to Evaluate the Correlation Between Spontaneous Catch-up Growth, Clinical Response to Saizen (Recombinant Human Growth Hormone, r-hGH) and Gene Ex...
    Medical condition: Small for Gestational Age
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-004090-28 Sponsor Protocol Number: Fx-R-001-S1/B3461049 Start Date*: 2014-05-13
    Sponsor Name:Fold RX Pharmaceuticals, a Pfizer Company
    Full Title: TRANSTHYRETIN-ASSOCIATED AMYLOIDOSES OUTCOMES SURVEY (THAOS) – OPTIONAL BLOOD SAMPLE COLLECTION SUBSTUDY
    Medical condition: Transthyretin (TTR) a 127-amino acid, tetrameric protein, primarily synthesized in the liver, is a secreted protein present in the blood and cerebrospinal fluid and is a carrier of thyroxine and r...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003673-34 Sponsor Protocol Number: BioCellThyr Start Date*: 2018-04-05
    Sponsor Name:Oslo University Hospital, Department of Endocrinologi, Morbid Obesity and Preventive Medicine
    Full Title: Identification of non-responders to levothyroxine-therapy: development of biomarkers reflecting T4 and T3 action at the tissue level
    Medical condition: Women with dysregulated hypothyroidism
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023783-41 Sponsor Protocol Number: E7080-G000-303 Start Date*: 2011-07-05
    Sponsor Name:Eisai Limited
    Full Title: A Multicenter, Randomized, Double- Blind, Placebo-Controlled, Phase 3 Trial of Lenvatinib (E7080) in 131I- Refractory Differentiated Thyroid Cancer
    Medical condition: 131I-refractory differentiated thyroid cancer (DTC)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10055107 Thyroid cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) PT (Completed) GB (Completed) DE (Completed) ES (Completed) PL (Completed) DK (Completed) AT (Completed) IT (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004451-35 Sponsor Protocol Number: MRTSH01505 Start Date*: 2007-03-13
    Sponsor Name:Genzyme Europe BV
    Full Title: Study to Evaluate the Dose, Safety and Effectiveness of Modified-Release Recombinant Human Thyroid Stimulating Hormone (MRrhTSH) When Used in Conjunction with Radioiodine for the Treatment of Multi...
    Medical condition: Nodular goiter are clinically recognizable enlargements of the thyroid gland characterized by excessive growth and structural and or functional transformation of one or several areas within the nor...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043808 Thyrotropin LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) FR (Completed) DE (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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