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Clinical trials for Ticagrelor

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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    122 result(s) found for: Ticagrelor. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2012-004560-21 Sponsor Protocol Number: NL_ABR-43379 Start Date*: 2013-04-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The effect of ticagrelor on the adenosine system
    Medical condition: We will study in healthy volunteers the effect of ticagrelor on the vasodilator effect of dipyridamole
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-002391-13 Sponsor Protocol Number: PlinytheElder Start Date*: 2021-01-08
    Sponsor Name:AOU FEDERICO II
    Full Title: Platelet inhibition with Ticagrelor 60 mg versus Ticagrelor 90 mg twice daily in elderly patients with acute coronary syndrome (ACS).
    Medical condition: Acute coronary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005803-42 Sponsor Protocol Number: 2012-12 Start Date*: 2013-03-21
    Sponsor Name:Universitetssjukhuset Örebro
    Full Title: Evaluation of platelet function following cessation of ticagrelor - a study in patients with acute coronary syndrome and PCI with coronary stent
    Medical condition: Return of platelet function following cessation of oral anti-platelet treatment with ticagrelor
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000665-20 Sponsor Protocol Number: 2012-02 Start Date*: 2012-04-05
    Sponsor Name:Universitetssjukhuset Örebro
    Full Title: Evaluation of platelet function following cessation of ticagrelor - a study in patients with acute coronary syndrome and PCI with coronary stent
    Medical condition: Return of platelet function following cessation of oral anti-platelet treatment with ticagrelor.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-002675-17 Sponsor Protocol Number: TIGER-BVS Start Date*: 2014-05-30
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Ticagrelor and absorb bioresorbable vascular scaffold implantation for recovery of vascular function after successful chronic total occlusion recanalization
    Medical condition: Chronic total coronary occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-002227-96 Sponsor Protocol Number: 1 Start Date*: 2014-09-17
    Sponsor Name:County Council of Östergötland
    Full Title: Inhibition of platelet aggregation after administration of three different ticagrelor loading dose formulations in patients with stable angina referred for coronary angiography
    Medical condition: Effect of three ticagrelor loading dose formulations on the degree and rapidity of platelet aggregation in patients with stable angina referred for coronary angiography
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003621-33 Sponsor Protocol Number: ESR-15-10793 Start Date*: 2016-02-25
    Sponsor Name:Fundación Interhospitalaria de Investigación Cardiovascular
    Full Title: PRotective Effect on the coronary microcirculation of patients with DIabetes by Clopidogrel or Ticagrelor:A randomized multicenter clinical trial using intracoronary multimodal physiology
    Medical condition: Ischemic Heart Disease in Diabetic patients
    Disease: Version SOC Term Classification Code Term Level
    18.1 10007541 - Cardiac disorders 10072685 Microvascular coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-001661-27 Sponsor Protocol Number: ISSBRIL0162 Start Date*: 2014-12-12
    Sponsor Name:Sociedad Española de Cardiología
    Full Title: Comparison of TIcagrelor and clopidogrel in patients with Coronary artery diseaSe and type 2 Diabetes Mellitus (TICS-DM): a randomized pharmacodynamic study
    Medical condition: Coronary artery disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002586-64 Sponsor Protocol Number: ISS13616 Start Date*: 2016-10-13
    Sponsor Name:ELKE University of Athens
    Full Title: A randomized, pharmacodynamic study of cangrelor administration in STEMI patients loaded with ticagrelor
    Medical condition: In the present study, in STEMI patients undergoing primary PCI we aim therefore to compare platelet inhibition achieved in patients loaded with ticagrelor followed by cangrelor (bolus plus infusion...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005420-10 Sponsor Protocol Number: D5136C00008 Start Date*: 2015-09-22
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, double-blind, double-dummy, parallel-group, multicenter, phase IIb study to evaluate the effect of ticagrelor 10 mg and 45 mg bid versus placebo in reducing the number of days with pa...
    Medical condition: Investigating the number of days of pain in SCD patients.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-003218-36 Sponsor Protocol Number: 82646 Start Date*: 2023-06-05
    Sponsor Name:Radboudumc
    Full Title: The safety of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction and the effect on intramyocardial haemorrhage
    Medical condition: Acute myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002896-32 Sponsor Protocol Number: D5136C00001 Start Date*: 2013-01-16
    Sponsor Name:AstraZeneca AB
    Full Title: A multicenter, double-blind, placebo-controlled, pharmacokinetic, pharmacodynamic, safety and tolerability study in patients aged 12 to <18 years of age with a central venous catheter to support pr...
    Medical condition: Thrombosis, thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10050661 Platelet aggregation inhibition PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Ongoing) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005042-11 Sponsor Protocol Number: ISSBRIL0205 Start Date*: 2014-06-11
    Sponsor Name:Fundación Investigación Sanitaria en León
    Full Title: EndoTic ? Endothelium and Ticagrelor: Pharmacological effects beyond antiplatelet effect
    Medical condition: The use of ticagrelor in ACS is related to a reduction in the number of CECs and/or an increase in the number of EPCs from the baseline values as compared with clopidogrel.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004860-23 Sponsor Protocol Number: REACTIC2019-HAC Start Date*: 2020-05-22
    Sponsor Name:Andres Iñiguez Romo
    Full Title: REACTIC-TAVI TRIAL: Platelet REACtivity according to TICagrelor dose after Trancathter Aortic Valve Implantation. A pilot study.
    Medical condition: Patients with severe aortic stenosis submitted for Transcatheter Aortic Valve Implantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003621-36 Sponsor Protocol Number: 20-126 Start Date*: 2021-02-10
    Sponsor Name:CHU CAEN Normandie
    Full Title: Evaluation de la reperfusion myocardique et de la masse thrombotique endocoronaire après angioplastie primaire pour infarctus du myocarde sous cangrelor en intraveineux en plus du ticagrelor per os...
    Medical condition: Patients admis pour angioplastie coronaire primaire (PPCI) pour infarctus du myocarde avec sus-décalage du segment ST (IDM ST+)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004190-46 Sponsor Protocol Number: D5136C00013 Start Date*: Information not available in EudraCT
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomised, Double-Blind, Parallel-Group, Multicentre, Phase III Study to Evaluate the Effect of Ticagrelor versus Placebo in Reducing the Number of Vaso-Occlusive Crises in Paediatric Patients A...
    Medical condition: Sickle Cell Disease
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004850 10040645 Sickle cell disease NOS LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002671-26 Sponsor Protocol Number: 9113 Start Date*: 2017-12-19
    Sponsor Name:Isala
    Full Title: The effect of Opioids on P2Y12 Receptor Inhibition in patients with ST-Elevation Myocardial Infarction who are pre-treated with crushed Ticagrelor
    Medical condition: Acute Coronary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000011652 10064346 STEMI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017242-30 Sponsor Protocol Number: D5132C00001 Start Date*: 2010-12-06
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events with Ticagrelor Compared to Placebo on a Background of Acetyl Sali...
    Medical condition: Myocardial Infarction, Cardiovascular Death, Atherothombosis, Stroke
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004849 10007648 Cardiovascular disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) GB (Completed) DE (Completed) HU (Completed) RO (Completed) CZ (Completed) SK (Completed) PL (Completed) BE (Completed) ES (Completed) SE (Completed) IT (Completed) NO (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2014-004783-38 Sponsor Protocol Number: STH18423 Start Date*: 2015-02-04
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Study of two regimens of TicagrElor compared to clopidogrel in patients undergoing ELective Percutaneous Coronary Intervention (STEEL PCI)
    Medical condition: Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10052086 Coronary arterial stent insertion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-000823-11 Sponsor Protocol Number: TIMO Start Date*: 2023-03-09
    Sponsor Name:Sahlgrenska University Hospital Gothenburg
    Full Title: Ticagrelor monotherapy after coronary stenting in patients with acute myocardial infarction. A prospective single-centre, single-arm phase II study
    Medical condition: Antiplatelet therapy in patients who undergo coronary artery stenting due to coronary artery disease (CAD) or acute coronary syndrome (ACS). The present study will examine whether ticagrelor, as mo...
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004849 10048560 Coronary artery disease aggravated LLT
    20.0 100000004849 10071111 Non ST segment elevation acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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