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Clinical trials for Tonsils

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    30 result(s) found for: Tonsils. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2013-000492-32 Sponsor Protocol Number: T16/2013 Start Date*: 2013-07-10
    Sponsor Name:Turku University Hospital
    Full Title: T cell and interferon expression in tonsils after sublingual immunotherapy and/or nasal live attenuated influenza vaccine
    Medical condition: We investigate the effects of allergen and virus on patients with recurrent tonsillitis or tonsillar hypertrphy.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004620-10 Sponsor Protocol Number: 719-13 Start Date*: 2014-12-22
    Sponsor Name:Johan Hellgren
    Full Title: A double blind, placebo controlled randomized study of nasal steroid spray treatment on the quality of life and objective sleep parameters in children with sleep disorder breathing.
    Medical condition: Sleep disordered breathing due to enlarged tonsils and/or adenoid
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001430-34 Sponsor Protocol Number: 10-TT-EP-003 Start Date*: 2012-08-14
    Sponsor Name:Deutsche Homöopathie-Union, DHU-Arzneimittel GmbH & Co. KG
    Full Title: Therapeutic effectiveness, safety and tolerability of Tonsilotren tablets in patients (6 to 60 years old) with chronic tonsillitis. A randomized, international, multicenter, controlled clinical t...
    Medical condition: Chronic tonsillitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10009152 Chronic tonsillitis PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-003119-50 Sponsor Protocol Number: HYKSKIPU2011-1 Start Date*: 2011-08-17
    Sponsor Name:Vesa Kontinen
    Full Title: Topical anaesthesia for postoperative pain in adult patients undergoing tonsillectomy
    Medical condition: Adult patients undergoing tonsillectomy
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10044006 Tonsillectomy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005789-38 Sponsor Protocol Number: HU03/ANE/DEXA Start Date*: 2006-12-11
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola (H.U.D.E.R.F.)
    Full Title: Dexaméthasone et Amygdalectomie
    Medical condition: Children aged from 2 to 8 years old requiring tonsillectomy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10044008 Tonsillitis LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002862-15 Sponsor Protocol Number: BupivacTons20 Start Date*: 2021-03-03
    Sponsor Name:Nordland Hospital. Bodø. Dep of Surgery
    Full Title: Can topical anaesthesia with bupivacaine reduce pain after tonsillectomy?
    Medical condition: Local pain after tonsillectomy, both at rest and during swallowing. Assessed by self-reporting at 1, 2, 3, 4, 5, 6 hours and 1,2,4 and 6 days after surgery.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003856-19 Sponsor Protocol Number: CVB2018-2 Start Date*: 2019-01-09
    Sponsor Name:Department of Otorhinolaryngology, Head and Neck Surgery and Audiology. Rigshospitalet, University Hospital of Cph, DK
    Full Title: A Phase I Open Label Study Evaluating the Safety and Feasibility of Allogeneic Mesenchymal stem cells for radiation-induced hyposalivation and xerostomia in previous oropharyngeal patients
    Medical condition: The trial will include participants with Xerostomia ( International Classification of Diseases-10: DQ 838A)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10048223 Xerostomia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-001259-63 Sponsor Protocol Number: Pollenvaccine2014-01-15 Start Date*: 2016-03-09
    Sponsor Name:Department of Clinical Science, Intervention and Technology, Karolinska Institute
    Full Title: Intralymphatic immunotherapy in increasing doses up to 10 000 SQ-U -a human randomized clinical trial
    Medical condition: Patients with severe to moderate Allegic rhinitis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014827-21 Sponsor Protocol Number: RD–5103-009-08 Start Date*: 2010-09-02
    Sponsor Name:Derby Hospitals NHS Foundation Trust [...]
    1. Derby Hospitals NHS Foundation Trust
    2. Derby Hospitals NHS Foundations Trust
    Full Title: A single centre double blind randomised controlled trial investigating the use of dexamethasone in the treatment of acute tonsillitis.
    Medical condition: Acute bacterial tonsillitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-000756-34 Sponsor Protocol Number: StrepA-negativetonsillitis2019 Start Date*: 2019-05-29
    Sponsor Name:Region Jönköping County
    Full Title: The SANT - study A randomized controlled clinical trial of Streptococcus group A-negative acute tonsillitis in primary health care - a comparison of phenoxymethylpenicillin and no antibiotic treatm...
    Medical condition: J03.0 Pharyngotonsillitis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-004188-25 Sponsor Protocol Number: ASST_FARM_ONCO_P-ACC_2022 Start Date*: 2023-03-03
    Sponsor Name:AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA
    Full Title: P-ACC Trial - Phase II, single arm, multicenter, open-label study of PARP inhibitors + cisplatin in Recurrent and/or Metastatic Adenoid Cystic Carcinoma
    Medical condition: patients with recurrent and/or Metastatic Adenoid Cystic Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10053231 Adenoid cystic carcinoma PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10073370 Adenoid cystic carcinoma of salivary gland PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10053231 Adenoid cystic carcinoma PT
    24.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10085951 Adenoid cystic carcinoma metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000048-28 Sponsor Protocol Number: EC002(Quad1) - C59P1 Start Date*: 2007-06-22
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: An open lable, randomised, controlled two centre study to evaluate the mucosal immune response to a quadrivalent meningococcal conjugate vaccine in healthy adults.
    Medical condition: Prevention of meningococcal infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027274 Meningococcal infection LLT
    9.1 10046859 Vaccination LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-001261-16 Sponsor Protocol Number: Betapred_vid_tonsillektomi Start Date*: 2018-10-02
    Sponsor Name:ÖNH-kliniken Sunderby Sjukhus
    Full Title: Betamethasone (Betapred®) as premedication for reducing postoperative vomiting and pain after tonsillectomy – a randomized, double-blind, placebo-controlled trial
    Medical condition: Postoperative pain, nausea and vomiting following tonsillectomy in patients with chronic or recurrent tonsillitis.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001611-30 Sponsor Protocol Number: AJAE1001 Start Date*: 2006-08-22
    Sponsor Name:Hammersmith Hospital NHS Trust
    Full Title: Clinical trial comparing the effect of Acetaminophen and Ibuprofen on the duration of influenza viral shedding in young children (Pilot study)
    Medical condition: Influenza in children [positive rapid diagnostic test (QuickVue influenza test)confirmed by influenza PCR] Infants and young children shed the influenza virus for longer periods than adults, durat...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2021-001425-48 Sponsor Protocol Number: BLUEBERRY Start Date*: 2021-07-07
    Sponsor Name:Division of Anaesthesiology - Department of Acute Medicine - Geneva Children's Hospital, University Hospitals of Geneva
    Full Title: Dexamethasone and postoperative bleeding following tonsillectomy in children
    Medical condition: Tonsillectomy/tonsillotomy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001314-17 Sponsor Protocol Number: ANICK01 Start Date*: 2007-07-10
    Sponsor Name:ERASME HOSPITAL
    Full Title: EVALUATION OF A PROTOCOLE FOR ADENOTONSILLECTOMY IN CHILDREN
    Medical condition: CHILDREN AGED 2 TO 10 YEAR OF AGE SCHEDULED FOR ADENOTONSILLECTOMY IN A ONE DAY HOSPITAL
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001256 Adenotonsillectomy LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001119-19 Sponsor Protocol Number: A0661206 Start Date*: 2016-04-13
    Sponsor Name:Pfizer Inc.
    Full Title: Ocular Effects Of Azithromycin Oral Solution In Pediatric Patients With Pharyngitis/tonsillitis
    Medical condition: pharyngitis/tonsillitis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10034835 Pharyngitis PT
    19.0 10021881 - Infections and infestations 10044008 Tonsillitis PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-004245-29 Sponsor Protocol Number: 501 Start Date*: 2008-12-08
    Sponsor Name:R&D Dept Raigmore Hospital, Inverness
    Full Title: Single Dose Dexamethasone following Aspiration of a Peri-tonsillar Abscess: A Randomised Placebo-Controlled Trial
    Medical condition: Peri-tonsillar abscess is a common cause for emergency admission to an ENT ward. In Raigmore there are 2-3 admissions per week with a quinsy. The standard management is needle aspiration under loca...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037737 Quinsy LLT
    9.1 10034686 Peritonsillar abscess LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-000066-22 Sponsor Protocol Number: BAY 43-9006 Start Date*: 2008-04-30
    Sponsor Name:Christie Hospital NHS Foundation Trust
    Full Title: A Phase 2 study of Sorafenib (BAY 43-9006) in patients with advanced salivary Adenoid Cystic Carcinoma
    Medical condition: advanced salivary adenoid cystic carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053231 Adenoid cystic carcinoma PT
    9.1 10051975 Salivary gland carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001927-74 Sponsor Protocol Number: SysVac01-C60P2 (PA/2008/2883) Start Date*: 2009-01-16
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: A PHASE II, OPEN LABEL, RANDOMISED, TWO CENTRE STUDY TO EVALUATE THE IMPORTANCE OF NATURALLY INDUCED IMMUNE REGULATION ON THE MUCOSAL IMMUNE RESPONSE TO MENINGOCOCCAL SEROGROUP B OUTER MEMBRANE VES...
    Medical condition: "Healthy volunteers" In this project we will establish whether naturally induced mucosal CD25+ T regulatory activity in adults and adolescents modulates the mucosal immune response to systemic Me...
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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