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Clinical trials for Transplantation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,853 result(s) found for: Transplantation. Displaying page 1 of 93.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2007-004284-21 Sponsor Protocol Number: 987 Start Date*: 2007-07-06
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: A prospective randomized study of antibiotic prophylaxis for renal transplantation: short term vs standard treatment
    Medical condition: antibiotic prophylaxis for renal tranplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038533 Renal transplant LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012258-19 Sponsor Protocol Number: F506-CL-0403 Start Date*: 2011-03-09
    Sponsor Name:Astellas Pharma Europe Ltd.
    Full Title: A Multicentre, Open-label, Pharmacokinetic Study of Modigraf® (Tacrolimus granules) in de novo Paediatric Allograft Recipients.Estudio Abierto, Multicéntrico, Farmacocinético de Modigraf® (Tacróli...
    Medical condition: De novo allograft transplantation (liver, heart, kidney) in paediatric patients. Pacientes pediátricos que reciben un trasplante de aloinjerto de novo ( hígado, corazón y riñón)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10024716 Liver transplantation LLT
    13.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    13.1 10042613 - Surgical and medical procedures 10023438 Kidney transplant LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed) DE (Completed) BE (Completed) FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2014-003707-30 Sponsor Protocol Number: P140501 Start Date*: 2014-10-23
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004459-38 Sponsor Protocol Number: TREACE_2015 Start Date*: 2016-02-24
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
    Full Title: EXPLORATIVE STUDY TO IDENTIFY A SPECIFIC TRANSCRIPTOMIC PROFILE FOR PREDICTING THE MAJOR ADVERSE EFFECTS ASSOCIATED WITH CERTICAN (EVEROLIMUS) IN RENAL TRANSPLANT RECIPIENTS: A PHARMACOGENOMIC APPR...
    Medical condition: kidney transplant
    Disease: Version SOC Term Classification Code Term Level
    21.0 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    21.0 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001496-35 Sponsor Protocol Number: ISRCTN07963178 Start Date*: 2006-02-13
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: A single centre, randomised controlled, open label study of rituximab as induction therapy in kidney transplantation.
    Medical condition: Renal Transplantation
    Disease: Version SOC Term Classification Code Term Level
    7.1 10038533 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004069-16 Sponsor Protocol Number: CYP3A4/5RenalTx Start Date*: 2007-10-19
    Sponsor Name:Department of Nephrology and Renal Transplantation, KU Leuven
    Full Title: Hepatic and intestinal CYP3A4/5 activity in renal transplantation. A study assessing in vivo hepatic and intestinal CYP3A4/5 activity at different time-points and in different clinical settings af...
    Medical condition: Effect of genetic (single nucleotide polymorphisms of genes encoding drug metabolising enzymes and drug transporters) and non-genetic factors (e.g. age, time after transplantation, concommitant me...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038533 Renal transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-019126-13 Sponsor Protocol Number: CE-US Start Date*: 2011-03-04
    Sponsor Name:IST. DI RICERCHE FARMACOLOG. M. NEGRI
    Full Title: A PILOT, EXPLORATIVE STUDY TO IDENTIFY CONTRAST-ENHANCED ULTRASOUND (CE-US) PATTERNS THAT CHARACTERIZE ACUTE ALLOGRAFT REJECTION AND OTHER CAUSES OF ACUTE ALLOGRAFT DYSFUNCTION IN RENAL TRANSPLANT ...
    Medical condition: Renal transplant
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006072-30 Sponsor Protocol Number: 0808100 Start Date*: 2009-01-19
    Sponsor Name:CHU Saint-Etienne
    Full Title: Mycophénolate sodic in graded increased doses in the first 3 months of renal transplantation _ Pharmacokinetic descriptive Pilot study
    Medical condition: renal transplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038533 Renal transplant LLT
    9.1 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015890-11 Sponsor Protocol Number: AGO/2009/007 Start Date*: 2009-11-03
    Sponsor Name:University Hospital Ghent
    Full Title: Conditioning with volatile anesthetics in liver transplantation
    Medical condition: Liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    12.0 10024716 Liver transplantation LLT
    Population Age: Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004158-33 Sponsor Protocol Number: CYP3A4/5+PGPinRenalTx Start Date*: 2008-09-17
    Sponsor Name:Department of Nephrology and Renal Transplantation, KU Leuven
    Full Title: CYP3A4/5 and PGP activity in renal transplantation. A study assessing in vivo hepatic and intestinal CYP3A4/5 and PGP activity in kidney transplant recipients and its relationship with genetic and...
    Medical condition: Effect of genetic (single nucleotide polymorphisms of genes encoding drug metabolising enzymes and drug transporters) and non-genetic factors (e.g. age, time after transplantation, concommitant med...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038533 Renal transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002763-27 Sponsor Protocol Number: PRINS study Start Date*: 2007-09-12
    Sponsor Name:Erasmus MC
    Full Title: A multi-center, randomized, controlled trial with programmed introduction of Sirolimus-based, Calcineurin inhibitor free immunosuppression in recipients of non-heart-beating donor kidney grafts.
    Medical condition: Recipients of a renal allograft from a non-heart-beating donor, three months after transplantation.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014997-16 Sponsor Protocol Number: MPASNP1 Start Date*: 2010-04-08
    Sponsor Name:Medizinische Universität Wien, Abteilung für Nephrologie und Dialyse
    Full Title: Identification of patients with high probability of not or poorly responding to therapy with mycophenolic acid pro-drugs.
    Medical condition: Patients with a de novo kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-000771-42 Sponsor Protocol Number: CRAD001ASE01 Start Date*: 2007-10-20
    Sponsor Name:Novartis Pharma Services
    Full Title: A controlled randomized open-label multicentre study evaluatiing if early conversion to everolimus (Certican) from cyclosporine (Neoral) in de novo renal transplant receipients can improve long-ter...
    Medical condition: Renal Transplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-002938-38 Sponsor Protocol Number: MHH – EPONTX – 01/06 Start Date*: 2006-11-17
    Sponsor Name:Hannover Medical School
    Full Title: EFFECT OF ERYTHROPOIETIN ON RENAL FUNCTION AFTER KIDNEY TRANSPLANTATION
    Medical condition: We will investigate the effect of recombinant human erythropoietin (rHuEPO) on ischemia-reperfusion injury in patients with terminal renal failure undergoing cadaveric kidney transplantation. In th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021333-31 Sponsor Protocol Number: TOP2010-LMU Start Date*: 2011-08-23
    Sponsor Name:Klinikum der Universität München
    Full Title: Reduktion des Ischämie-Reperfusionsschadens durch ex-vivo Tacrolimus-Perfusion marginaler Organe vor Lebertransplantation (Tacrolimus-Organ-Perfusion TOP-Studie)
    Medical condition: Chonical terminal liver insufficiency
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10024714 Liver transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002856-17 Sponsor Protocol Number: SMHREN0501 Start Date*: 2006-12-28
    Sponsor Name:Hammersmith Hospital NHS Trust
    Full Title: A randomised controlled comparison of Campath−Tacrolimus vs IL2R MoAb −Tacrolimus / Mycophenolate as Induction−Maintenance immunosuppression in kidney transplantation.
    Medical condition: Renal transplant failure and rejection (Live and deceased donor)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-013461-25 Sponsor Protocol Number: UK-02-RG-194_09.0098 Start Date*: 2010-03-03
    Sponsor Name:St. George's, University of London
    Full Title: The influence of CYP3A5 and ABCB1 genotype on the pharmacokinetics of twice daily Tacrolimus and Advagraf
    Medical condition: Renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003561-15 Sponsor Protocol Number: MYSTEP1 Start Date*: 2016-08-30
    Sponsor Name:University Hospital of Tuebingen
    Full Title: Safety and Tolerance of Immunomodulating Therapy with Donor-specific Mesenchymal Stem Cells in Pediatric Living-Donor Liver Transplantation
    Medical condition: Side effects of life-long immunosuppressive medication account for major morbidity after pediatric liver transplantation and impair quality of life. In-vivo and in-vitro studies have shown that MSC...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10024716 Liver transplantation LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013074-41 Sponsor Protocol Number: CRAD001ANO02 Start Date*: 2009-11-10
    Sponsor Name:Novartis Norge AS
    Full Title: A controlled randomized open-label multicentre study evaluating if early initiation of everolimus (Certican®)and early elimination of cyclosporine (Sandimmun Neoral®) in de novo heart transplant re...
    Medical condition: Heart transplantation
    Disease: Version SOC Term Classification Code Term Level
    16.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2014-004101-33 Sponsor Protocol Number: 0468E-102362 Start Date*: 2015-04-07
    Sponsor Name:Wyeth Korea, Inc.
    Full Title: A Clinical Study to Evaluate the Efficacy and Safety of Cyclosporine (CsA) and Sirolimus (SRL) Induction Followed by Cyclosporine Withdrawal in Korean Renal Allograft Recipients
    Medical condition: Renal transplantation
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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