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Clinical trials for Vigilance

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    71 result(s) found for: Vigilance. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2017-002288-16 Sponsor Protocol Number: MOCAFFE Start Date*: 2018-01-24
    Sponsor Name:Center for Man in Aviation
    Full Title: Effects of Modafinil and Caffeine during the circadian trough on vigilance in healthy RNLAF aircrew: a randomized controlled trial
    Medical condition: fatigue in healthy aircew
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-001160-36 Sponsor Protocol Number: 2008-1 Start Date*: 2009-06-04
    Sponsor Name:Imperial College London
    Full Title: A trial of Guanfacine, an alpha 2 adrenergic agonist, for Spatial Neglect and Impaired Vigilance following Stroke and Focal Brain Damage
    Medical condition: Spatial Neglect following Hemispheric stroke and focal brain injury
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10050400 Vigilance decreased LLT
    14.0 10029205 - Nervous system disorders 10029289 Neurologic neglect syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023992-24 Sponsor Protocol Number: MEMAP1 Start Date*: 2011-08-26
    Sponsor Name:University of Leipzig
    Full Title: International randomised double-blind placebo-controlled study on the initial treatment of acute mania with methylphenidate
    Medical condition: acute mania and hypomania (ICD-10: F30.0, F30.1, F31.0, F31.1)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004873 10000852 Acute mania LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended) BE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2015-000488-15 Sponsor Protocol Number: 3.0 Start Date*: 2015-10-07
    Sponsor Name:University of Leipzig
    Full Title: Vigilance regulation as predictor of response to Psychostimulants in adult patients with ADHD
    Medical condition: Attention deficit-hyperactivity disorder
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10003735 Attention deficit-hyperactivity disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007174-35 Sponsor Protocol Number: AM-KS-IV/5/07 Start Date*: Information not available in EudraCT
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: Randomized, placebo-controlled phase-IV clinical trial for the application of physostigmine salicylate for an early post-operative restoration of vigilance and cognition after cardiopulmonary bypas...
    Medical condition: post-operative restoration of vigilance and cognition after cardiopulmonary bypass surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066123 Cardiopulmonary bypass LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004082-41 Sponsor Protocol Number: DELIcu Start Date*: 2013-03-06
    Sponsor Name:Dekan of Faculty of Medicine of Goethe-University Frankfurt
    Full Title: Monocenter, double blind, randomised, placebo controlled study t evaluate Physostigmin for the Treatment of delirium in perioperative intensive care medicine
    Medical condition: patients with delirium in perioperative intensive care medicine
    Disease: Version SOC Term Classification Code Term Level
    17.1 10037175 - Psychiatric disorders 10012221 Deliria (incl confusion) HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-002418-18 Sponsor Protocol Number: 2021-10 Start Date*: 2022-11-09
    Sponsor Name:University Hospital Tübingen
    Full Title: AmaNtadine for NeuroenhancEment in acutE patients Study - A prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)
    Medical condition: Patients on Intermediate Care and Intensive Care Unit (IMC and ICU) with unresponsive wakefulness syndrome not otherwise explained
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001101-14 Sponsor Protocol Number: 750253.01.030 Start Date*: 2016-03-09
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Driving fitness under acute and subchronic application of Silexan® (WS® 1265) in comparison to placebo and Lorazepam with healthy volunteers in two successive, randomized, double-blind, crossover d...
    Medical condition: Investigation in healthy volunteers. The investigational medicinal product has a marketing authorisation in Germany for the treatment of restlessness related to anxious mood.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003770-32 Sponsor Protocol Number: CLR_14_05 Start Date*: 2016-01-04
    Sponsor Name:Sun Pharma Advanced Research Company
    Full Title: A Randomized, Double-Blind, Four Treatment, Four period, Crossover Study, with Placebo, Tizanidine Immediate Release and Diphenhydramine to Study the Effect of Tizanidine Extended Release on Simula...
    Medical condition: healthy volunteers (acute musculoskeletal pain)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-005012-25 Sponsor Protocol Number: 05-07/BF 2.649 Start Date*: 2006-01-24
    Sponsor Name:BIOPROJET
    Full Title: Single blind study to assess the efficacy and tolerance of BF 2.649 in adults suffering from Attention Deficit/Hyperactivity Disorder
    Medical condition: Attention Deficit/Hyperactivity Disorder (AD/HD) in adults
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-000777-80 Sponsor Protocol Number: SENS111-202 Start Date*: 2018-06-08
    Sponsor Name:Sensorion
    Full Title: A randomized, cross-over, placebo controlled, and meclizine calibrated study to assess the safety and pharmacodynamic effects of SENS-111 (100 mg and 200 mg) single dose in healthy subjects exposed...
    Medical condition: healthy volunteers (medicine for acute unilateral vertigo)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-000547-28 Sponsor Protocol Number: 070774 Start Date*: 2006-01-15
    Sponsor Name:Department of Psychiatry; Section of Sleep Research and Pharmacopsychiatry
    Full Title: EEG and ERP tomography by means of LORETA (Low-Resolution Brain Electromagnetic Tomography) identifying essential brain regions for vigilance and cognition in narcolepsy: double-blind, placebo-cont...
    Medical condition: Patients complaining of excessive daytime sleepiness will be recruited from our sleep clinics and will be subjected to neuropsychiatric, physical, laboratory and neurophysiological screening examin...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001839-23 Sponsor Protocol Number: 14137A Start Date*: 2012-05-14
    Sponsor Name:H. Lundbeck A/S
    Full Title: Interventional randomised, double-blind, parallel-group, placebo-controlled, exploratory study investigating the effects of Lu AA21004 on cognition and BOLD fMRI signals in subjects remitted fro...
    Medical condition: Cognitive dysfunction Major depressive disorder (MDD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012419-16 Sponsor Protocol Number: PIR-007/K Start Date*: 2009-12-03
    Sponsor Name:Desitin Arzneimittel GmbH
    Full Title: Influence of the Non-Ergot Dopamine agonist Piribedil on vigilance and cognitive function in patients with Parkinson's disease compared to other oral Non-Ergot Dopamine agonists
    Medical condition: idiopathic Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    12.0 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003299-22 Sponsor Protocol Number: BILA-3514/SCA Start Date*: 2014-11-18
    Sponsor Name:TNO.Netherlands Organization for Applied Scientific Research
    Full Title: Effects of Single Dose of Bilastine 20mg on Flying Ability in Healthy Volunteers Under Conditions of Simulated Cabin Pressure
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003460-31 Sponsor Protocol Number: COP13.058 Start Date*: 2014-03-03
    Sponsor Name:GGZ-Drenthe
    Full Title: The effect of low doses of mirtazapine and quetiapine on sleep and daytime functioning.
    Medical condition: Insomnia
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001801-42 Sponsor Protocol Number: EPU-P76 Start Date*: 2014-11-25
    Sponsor Name:Maastricht University
    Full Title: Sensitivity of driving-related psychometric tests to the effects of two widely prescribed benzodiazepines: diazepam and oxazepam
    Medical condition: None
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000078-30 Sponsor Protocol Number: MB0612/1860/02 Start Date*: 2013-05-09
    Sponsor Name:Valeas SpA
    Full Title: Evaluation in patients affected by middle of the night (MONT) awakenings using different dosages of triazolam
    Medical condition: Insomnia characterized by difficulty returning to sleep following a nocturnal awakening, otherwise called middle-of-the-night (MONT) insomnia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004873 10029448 Nocturnal awakening LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-001512-38 Sponsor Protocol Number: EPU-P87 Start Date*: 2016-10-10
    Sponsor Name:Maastricht University
    Full Title: Investigation of psychomotor performance to evaluate clinical impairment and pharmacokinetic aspects of methadone and buprenorphine: a double-blind placebo-controlled randomized trial
    Medical condition: None
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004048-50 Sponsor Protocol Number: 3-062-18 Start Date*: 2019-02-14
    Sponsor Name:University of Aberdeen [...]
    1. University of Aberdeen
    2. NHS Grampian
    Full Title: Double blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM-CP)
    Medical condition: Sleep disturbance in patients with chronic pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10040995 Sleep disturbance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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