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Clinical trials for near-infrared fluorescence imaging

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    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    22 result(s) found for: near-infrared fluorescence imaging. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2019-002442-20 Sponsor Protocol Number: 2019/2886 Start Date*: 2020-02-15
    Sponsor Name:Gustave Roussy
    Full Title: Study evaluating near infrared imaging coupled with indocyanine green for preoperative control of resection margins in ENT surgery.
    Medical condition: visualization of the resection margins by near infrared fluorescence imaging (in vivo and ex vivo) for patients over 18 years of age with ENT epidermoid cancer treated by open surgery or by robot-a...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067821 Head and neck cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-000509-96 Sponsor Protocol Number: NL71166.041.19 Start Date*: 2020-05-14
    Sponsor Name:Princess Maxima Center for pediatric oncology
    Full Title: Near-infrared fluorescence imaging using indocyanine green as an adjunct to improve standard-of-care sentinel lymph node procedure in pediatric patients with melanoma or sarcoma of head/neck/trunk,...
    Medical condition: Sentinel node procedure for pediatric patients with melanoma or sarcoma
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001954-32 Sponsor Protocol Number: 1719 Start Date*: 2017-11-09
    Sponsor Name:LUMC
    Full Title: Near-infrared Fluorescence-Enhanced Identification of the Ureters using ZW800-1
    Medical condition: The trial is conducted in patients where ZW800-1 is used to visualize ureters during surgery.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004954-58 Sponsor Protocol Number: 2013-617 Start Date*: 2014-01-17
    Sponsor Name:Bispebjerg University Hospital
    Full Title: Near infrared imaging and measurement of extremity lymphatic collector function using indocyanine green
    Medical condition: Healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    19.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003268-19 Sponsor Protocol Number: BR-TUM-ICG-IV-2 Start Date*: 2014-10-06
    Sponsor Name:Jules Bordet Institute
    Full Title: Study evaluating breast cancer tumorectomy guided by Near-Infrared imaging after the intravenous injection of free Indocyanine Green
    Medical condition: Imaging of tumours and their margins after intravenous injection of Indocyanine Green to breast cancer patients
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003560-13 Sponsor Protocol Number: OTL-2016-OTL38-005 Start Date*: 2017-10-18
    Sponsor Name:On Target Laboratories, LLC
    Full Title: A Phase 2, Single dose, Open-Label, Exploratory Study to Investigate the Safety and Efficacy of OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
    Medical condition: adenocarcinoma lung cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10025044 Lung cancer LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003119-77 Sponsor Protocol Number: NL67828.058.18 Start Date*: 2020-02-24
    Sponsor Name:Leiden University Medical Center
    Full Title: Near-infrared fluorescence imaging with IndoCyanine Green for the intraoperative identification of Gastrointestinal stromal cell tumours: a pilot study
    Medical condition: GIST Gastrointestinal stromal cell tumour
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000985-12 Sponsor Protocol Number: 1719-B Start Date*: 2018-11-26
    Sponsor Name:Leiden University Medical Center
    Full Title: Near-infrared fluorescence imaging in kidney transplantations using ZW800-1 for perfusion assessment: a pilot study
    Medical condition: Patients undergoing a living-donor kidney transplantation (living kidney donor and kidney recipient)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005178-23 Sponsor Protocol Number: BR-TUM-ICG-IV Start Date*: 2014-01-30
    Sponsor Name:Jules Bordet Institute
    Full Title: Study of the (intravenously injected) Indocyanine Green distribution in the margins of breast cancer after tumorectomy
    Medical condition: Imaging of tumours and their margins after intravenous injection of Indocyanine Green to breast cancer patients
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003693-27 Sponsor Protocol Number: CHDR1854 Start Date*: 2019-02-06
    Sponsor Name:Leiden University Medical Center
    Full Title: Intraoperative near-infrared fluorescence imaging of endometriosis with OTL38: a pilot study
    Medical condition: Endometriosis
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000298-37 Sponsor Protocol Number: HN-ICG-LN-1 Start Date*: 2014-10-20
    Sponsor Name:Jules Borde Institute
    Full Title: Near-Infrared fluorescence imaging during neck dissection in head and neck cancer patients after peritumoral injection of Indocyanine Green (a feasibility study)
    Medical condition: Imaging of lymph nodes to be resected in head and neck cancers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004498-29 Sponsor Protocol Number: HN-ICG-IV-1 Start Date*: 2013-11-29
    Sponsor Name:Institut Jules Bordet
    Full Title: Near-Infrared fluorescence imaging during neck dissection in head and neck cancer patients after intravenous injection of Indocyanine Green (a feasibility study)
    Medical condition: Imaging of tumoral tissues and of lymph nodes to be resected in head and neck cancers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011079-57 Sponsor Protocol Number: BICG26UMCG-NIRF Start Date*: 2009-05-28
    Sponsor Name:University Medical Center Groningen
    Full Title: Evaluation of Indocyanine Green (ICG) enhanced Near-InfraRed Fluorescence (NIRF) Imaging for Intra-Operative Sentinel Lymph Node (SLN) detection in Breast Surgery.
    Medical condition: Women above the age of 21 with core biopsy or cytology proven breast cancer stage I and II, eligible for lumpectomy and sentinel lymph node procedure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006194 Breast cancer NOS stage I LLT
    9.1 10006195 Breast cancer NOS stage II LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004496-12 Sponsor Protocol Number: BR-ICG-IV-NACT Start Date*: 2013-12-05
    Sponsor Name:Institut Jules Bordet
    Full Title: Study of the (intravenously injected) ICG distribution in tumour bearing breasts and in axillary pieces of dissection of patients who have received neo-adjuvant therapy for histologically proven ma...
    Medical condition: imaging of tumours and their margins after intravenous injection of Indocyanine Green to breast cancer patients
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004217-14 Sponsor Protocol Number: P21.128 Start Date*: 2022-11-09
    Sponsor Name:Leiden University Medical Center
    Full Title: FLUOPANC-trial - Intraoperative near-infrared fluorescence imaging in pancreatic- and extrahepatic bile duct tumors using cRGD-ZW800-1 and dedicated imaging systems: A phase II feasibility, dose-ra...
    Medical condition: Pancreatic cancer (pancreatic carcinoma) Extrahepatic bile duct cancer (cholangiocarcinoma)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000424-18 Sponsor Protocol Number: ICTUC/32/2012 Start Date*: 2012-10-26
    Sponsor Name:Imperial College London
    Full Title: A study to assess near infrared laparoscopy with indocyanine green (ICG) for intraoperative lymphatic imaging and sentinel lymph node identification during standard surgical resection for colonic c...
    Medical condition: Bowel cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009944 Colon cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-000904-36 Sponsor Protocol Number: IBS-DOTIG-ECM-2202 Start Date*: 2022-05-09
    Sponsor Name:Instituto de Investigación Biomédica de Salamanca
    Full Title: Randomized clinical trial to evaluate the dose and administration time of indocyanine green in near-infrared fluorescent cholangiography during laparoscopic cholecystectomy.
    Medical condition: Laparoscopic cholecystectomy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10008611 Cholecystectomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2021-006454-30 Sponsor Protocol Number: 23537 Start Date*: 2023-02-09
    Sponsor Name:DIPARTIMENTO DI SCIENZE CHIRURGICHE - UNIVERSITà DEGLI STUDI DI TORINO
    Full Title: Near-infrared molecular imaging for lung cancer detection and treatment during mini-invasive surgery (Phase II Trial)
    Medical condition: To date, lung resection and lymphadenectomy remains the best curative option in patients with early-stage non-small cell lung cancer. Moreover, cancer screening programs have led to a frequent diag...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062042 Lung neoplasm PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062042 Lung neoplasm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2025-000122-33 Sponsor Protocol Number: 5354-CL-0301 Start Date*: 2025-04-16
    Sponsor Name:Astellas Pharma Global Development Inc.
    Full Title: A Phase 3, Multicenter, Prospective, Randomized, Open label Study for Intraoperative Ureter(s) Visualization When Using ASP5354 with Near infrared Fluorescence (NIR-F) Imaging in Participants Under...
    Medical condition: visualisation of ureter
    Disease: Version SOC Term Classification Code Term Level
    27.0 10022891 - Investigations 10068979 Imaging procedure PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2022-001361-12 Sponsor Protocol Number: FG001-CT-003 Start Date*: 2022-08-25
    Sponsor Name:FluoGuide A/S
    Full Title: An open-label, non-randomized, single center, single dose, exploratory phase II trial of FG001 (an imaging agent) for localization of oral and oropharyngeal squamous cell carcinoma
    Medical condition: Oral and oropharyngeal squamous cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041857 Squamous cell carcinoma of the oral cavity PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031112 Oropharyngeal squamous cell carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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