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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    26,035 result(s) found. Displaying page 1,000 of 1,302.
    EudraCT Number: 2008-005232-33 Sponsor Protocol Number: FE200486 CS30 Start Date*: 2009-04-15
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: A randomised, parallel arm, open-label trial comparing degarelix with goserelin plus anti-androgen flare protection (bicalutamide), in terms of prostate size reduction in prostate cancer patients o...
    Medical condition: Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed) DE (Completed) FR (Completed) ES (Completed) GB (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-001841-40 Sponsor Protocol Number: GW685698X Start Date*: 2005-10-05
    Sponsor Name:GlaxoSmithKline Research And Development Ltd
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of GW685698X Inhalation Powder 200mcg Twice-Daily, GW685698X Inhalation Powder ...
    Medical condition: Persistent asthma
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) LV (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015400-26 Sponsor Protocol Number: ARQ 197-A-U251 Start Date*: 2010-03-04
    Sponsor Name:Daiichi Sankyo Pharma Development
    Full Title: MULTICENTER PHASE 2 TRIAL OF ARQ 197 FOR SUBJECTS WITH RELAPSED OR REFRACTORY GERM CELL TUMORS
    Medical condition: Germ cell tumors (GCT) including testicular and non-central nervous system (non-CNS) extragonadal types.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10061184 Germ cell cancer LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male
    Trial protocol: DE (Completed) FR (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014246-29 Sponsor Protocol Number: BPS-MR-PAH-203 Start Date*: 2010-02-01
    Sponsor Name:Lung Rx
    Full Title: A 12-week, double-blind, international, multicenter, dose-response study of the safety and efficacy of Beraprost Sodium Modified Release (BPS-MR) in patients with pulmonary arterial hypertension (PAH)
    Medical condition: Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10064911 Pulmonary arterial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) BE (Prematurely Ended) DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2008-006344-19 Sponsor Protocol Number: D1532C00006 Start Date*: 2009-09-03
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase II, Double-Blind, Randomised Study to Assess the Efficacy of AZD6244 (Hyd-Sulfate) in Combination with Dacarbazine Compared with Dacarbazine Alone in First Line Patients with BRAF Mutation ...
    Medical condition: BRAF mutation positive advanced cutaneous and unknown primary melanoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025654 Malignant melanoma of sites other than skin LLT
    9.1 10025670 Malignant melanoma stage III LLT
    9.1 10025671 Malignant melanoma stage IV LLT
    9.1 10027152 Melanoma of skin (malignant) LLT
    9.1 10027480 Metastatic malignant melanoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) CZ (Completed) FR (Completed) SE (Completed) HU (Completed) ES (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-002833-70 Sponsor Protocol Number: s56892 Start Date*: 2014-12-18
    Sponsor Name:UZLeuven
    Full Title: Radium-223 in patients with PSA progression and without clinical metastases following maximal local therapy: a pilot study
    Medical condition: Patients with prostate cancer (PCa) who experience PSA progression and who are without detectable metastases following maximal local treatment consisting of radical prostatectomy (RP) + pelvic l...
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002007-41 Sponsor Protocol Number: 200603000 Start Date*: 2007-08-07
    Sponsor Name:AZIENDA OSPEDALIERA ORDINE MAURIZIANO
    Full Title: A Phase II Clinical Trial of Panitumumab in Combination with Infusional Oxaliplatin and Oral Capecitabine (XELOX) Chemotherapy as 1st line Therapy in Patients with Colorectal Cancer and Advanced Li...
    Medical condition: Previously untreated Patients with Colorectal Cancer and Advanced Liver Metastases.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052358 Colorectal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-017682-33 Sponsor Protocol Number: 2009_05/0943 Start Date*: 2010-03-11
    Sponsor Name:CHRU de Lille
    Full Title: L’intérêt de la Xylocaine® et de la kétamine per et postopératoire sur la prise en charge de la douleur postopératoire aigue et chronique après colectomie par Laparoscopie
    Medical condition: colectomie segmentaire ou totale
    Disease: Version SOC Term Classification Code Term Level
    12.1 10009879 Colectomy total LLT
    12.1 10009878 Colectomy partial LLT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005213-22 Sponsor Protocol Number: SUPREMES-01 Start Date*: Information not available in EudraCT
    Sponsor Name:Charite Universitätsmedizin Berlin
    Full Title: SUPREMES - Sunphenon in progressive forms of multiple sclerosis
    Medical condition: primary and secondary progressive forms of multiple sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000319-15 Sponsor Protocol Number: FLUGAZA Start Date*: 2014-07-25
    Sponsor Name:Fundación PETHEMA
    Full Title: A phase III, multicentre, randomized, open label clinical trial comparing azacytidine (Vidaza®) versus fludarabine plus cytarabine in elderly patients with newly diagnosed acute myeloid leukemia.
    Medical condition: Newly diagnosed acute myeloid leukemia.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10000886 Acute myeloid leukemia LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-013461-25 Sponsor Protocol Number: UK-02-RG-194_09.0098 Start Date*: 2010-03-03
    Sponsor Name:St. George's, University of London
    Full Title: The influence of CYP3A5 and ABCB1 genotype on the pharmacokinetics of twice daily Tacrolimus and Advagraf
    Medical condition: Renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005666-35 Sponsor Protocol Number: 2012-003-0301-CARD Start Date*: 2013-05-10
    Sponsor Name:Royal Wolverhampton NHS trust
    Full Title: Can Intravenous Iron Reduce Transfusion rates in Anaemic patients undergoing Cardiac Surgery
    Medical condition: Anaemic patients undergoing elective cardiac surgery Anaemia defined as follows: pre-operative haemoglobin levels in Female <11.5g/dl or Male <12.5g/dl
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10002034 Anaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000074-51 Sponsor Protocol Number: GBG 39 Start Date*: 2005-05-03
    Sponsor Name:GBG Forschungs GmbH
    Full Title: A multicenter phase II study to determine the efficacy of capecitabine as first line monochemotherapy in patients with HER2 negative, medium-risk, metastatic breast cancer
    Medical condition: patients with HER2 negative metastatic breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-011252-22 Sponsor Protocol Number: CeTeG Start Date*: 2010-07-09
    Sponsor Name:Medical Faculty, University of Bonn
    Full Title: Phase III trial of CCNU/temozolomide (TMZ) combination therapy vs. standard TMZ therapy for newly diagnosed MGMT-methylated glioblastoma patients (CeTeG)
    Medical condition: Newly diagnosed patients with glioblastoma harbouring a methylated MGMT promoter
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018336 Glioblastoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005036-28 Sponsor Protocol Number: 2012/41 Start Date*: 2013-04-12
    Sponsor Name:CENTRE ANTOINE LACASSAGNE
    Full Title: Pharmacogenetic study in castration-resistant prostate cancer patients treated with abiraterone acetate
    Medical condition: Prostate cancer metastatic
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-004599-36 Sponsor Protocol Number: SB012/01/2013 Start Date*: 2014-04-23
    Sponsor Name:sterna biologicals GmbH & Co. KG
    Full Title: SB012 for the treatment of active ulcerative colitis (SECURE): a prospective, multi-centre, randomised, double-blind, placebo-controlled phase IIa clinical trial to evaluate the efficacy, pharmacok...
    Medical condition: Active ulcerative colitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-006024-11 Sponsor Protocol Number: HD/BN-2005-MM-R Start Date*: 2006-11-08
    Sponsor Name:University hospital of Bonn
    Full Title: Prospective, open label, multi center phase II clinical trial of oral BAY 43-9006 (Sorafenib) in patients with relapsed or refractory multiple myeloma
    Medical condition: Relapsed or refractory multiple myeloma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004860-29 Sponsor Protocol Number: Panik-Cyclo Start Date*: 2007-05-11
    Sponsor Name:Charité- Universitätsmedizin Berlin
    Full Title: D-Cycloserine supported exposure in panic disorder
    Medical condition: Panic disorder agoraphobia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001340-21 Sponsor Protocol Number: KB046 Start Date*: 2013-01-15
    Sponsor Name:KEDRION
    Full Title: A Historically-Controlled Phase II/III study to Evaluate Efficacy and Safety of Kedrion Human Plasminogen Eye Drop Preparation in Patients Diagnosed with Ligneous Conjunctivitis
    Medical condition: Ligneous Conjunctivitis ( MedDRA Code vers. 15.0: 10071570 LLT - no present in OsSC database) associated with Type I Plasminogen Deficiency
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003557-27 Sponsor Protocol Number: SA-388-4-1 Start Date*: Information not available in EudraCT
    Sponsor Name:Dean of the Medical Faculty (University of Bonn)
    Full Title: Covered Transjugular Intrahepatic Portosystemic Stent Shunt versus Optimized medical Treatment for the Secondary Prevention of Variceal Bleeding in Cirrhosis
    Medical condition: liver cirrhosis; esophageal (variceal) bleeding
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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