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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,338 result(s) found. Displaying page 1,013 of 2,217.
    EudraCT Number: 2008-005442-23 Sponsor Protocol Number: 411-LY-08-01-0000 Start Date*: 2009-02-19
    Sponsor Name:Leyh Pharma GmbH
    Full Title: Evaluation of the efficacy and safety of nose spray containing 3% silver protein diacetyl tannate (SEAT) in patients with uncomplicated viral rhinitis. A placebo-controlled, randomized, multicentri...
    Medical condition: treatment of uncomplicated rhinal infections
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064948 Viral rhinitis LLT
    9.1 10066743 Acute rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008439-28 Sponsor Protocol Number: 1682/08 Start Date*: 2009-03-22
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effects of the addition of haloperidol on propofol requirements during sedation with propofol and remifentanil
    Medical condition: analgo-sedation in mechanically ventilated patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002182 Analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004761-26 Sponsor Protocol Number: 2008-004761-26 Start Date*: 2009-03-26
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA DELLA SECONDA UNIVERSITA` DEGLI STUDI DI NAPOLI
    Full Title: PILOT MULTICENTER OPEN STUDY TO EVALUATE EFFICACY AND TOLERABILITY OF PEG-INTERFERON ALFA-2A IN PATIENTS WITH ANTI-HBE POSITIVE CHRONIC HEPATITIS B WHO PRESENT RESIDUAL VIREMIA OR VIROLOGICAL REBOU...
    Medical condition: Patients with chronic hepatitis B, HBeAg-negative, on treatment with nucleos(t)ide analogues.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019654 Hepatic and hepatobiliary disorders HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-003866-16 Sponsor Protocol Number: AP REN 01-01 Start Date*: 2009-03-03
    Sponsor Name:AM-Pharma B.V.
    Full Title: A Phase-II, double-blind, randomized, placebo-controlled proof of concept study on the safety and early efficacy of Alkaline Phosphatase in sepsis patients with Renal Failure.
    Medical condition: Sepsis with Renal Failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040050 Sepsis NOS LLT
    9.1 10038435 Renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002357-23 Sponsor Protocol Number: BUP9007 Start Date*: 2009-03-12
    Sponsor Name:Newcastle Upon Tyne NHS Foundation Trust
    Full Title: An open label, randomized 2 part crossover study to investigate the effect of buprenorphine transdermal delivery system (BTDS) compared with co-codamol on physical activity in subjects aged 60 year...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002610-21 Sponsor Protocol Number: HOEK-02 Start Date*: Information not available in EudraCT
    Sponsor Name:Academic Medical Centre
    Full Title: Mechanisms of albuminuria in diabetes; reversal of injury to the glycocalyx by the ACE inhibitor lisinopril
    Medical condition: Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004881-16 Sponsor Protocol Number: P05633 Start Date*: 2009-06-10
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: The Effect of Acadesine on Clinically Significant Adverse Cardiovascular and Cerebrovascular Events in High-Risk Subjects Undergoing Coronary Artery Bypass Graft (CABG) Surgery Using Cardiopulmonar...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended) ES (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-006939-13 Sponsor Protocol Number: OAM4558g Start Date*: 2009-05-27
    Sponsor Name:Genentech, Inc.
    Full Title: A RANDOMIZED, PHASE II, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE SAFETY AND ACTIVITY OF MetMAb, A MONOVALENT ANTAGONIST ANTIBODY TO THE RECEPTOR MET, ADMINISTERED TO PATIE...
    Medical condition: Patients with advanced non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2007-003797-25 Sponsor Protocol Number: VOPO-PE-201 Start Date*: 2007-10-24
    Sponsor Name:Novartis Consumer Health SA
    Full Title: A randomized, double-blind, multi-center, vehicle-controlled, parallel group study to evaluate the efficacy and safety of diclofenac diethylamine 2.32% gel applied once or twice daily in subjects w...
    Medical condition: acute ankle sprain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002549 Ankle sprain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-006854-17 Sponsor Protocol Number: OPTIMDASATINIB 10/2008 Start Date*: 2009-03-03
    Sponsor Name:CH-Versailles
    Full Title: A PROSPECTIVE RANDOMIZED PHASE II STUDY EVALUATING THE OPTIMIZATION OF THE RESIDUAL PLASMATIC LEVEL OF DASATINIB (SPRYCEL®) IN PATIENTS NEWLY DIAGNOSED WITH CHRONIC PHASE CHRONIC MYELOGENOUS LEUKA...
    Medical condition: Chronic phase chronic myelogenous leukaemia (CP-CML).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006217-25 Sponsor Protocol Number: LIMON Start Date*: 2007-04-05
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Utilizzo intraoperatorio del verde indocianina-pulsion quale test predittivo di insufficienza epatica dopo resezione epatica maggiore
    Medical condition: Pazienti con neoplasie epatiche con indicazione chirurgica
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024408 LFTs LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010399-10 Sponsor Protocol Number: STAT Start Date*: 2009-04-16
    Sponsor Name:OSPEDALE G.PASQUINUCCI-FONDAZIONE G.MONASTERIO
    Full Title: STANDARD VERSUS TAILORED ANTI-PLATELET THERAPY IN ACS PATIENTS UNDERGOING PERCUTANEOUS CORONARY ANGIOPLASTY
    Medical condition: PATIENTS UNDERGOING CORONARY ANGIOPLASTY FOR ACUTE CORONARY SYNDROME TYPE STEMI / NSTEMI ESC
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047065 SOC
    9.1 10007541 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009858-24 Sponsor Protocol Number: CINC424A2352 Start Date*: 2009-05-18
    Sponsor Name:Novartis Pharma Services AG
    Full Title: COntrolled MyeloFibrosis Study with ORal JAK Inhibitor Treatment-II
    Medical condition: Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028537 Myelofibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) SE (Completed) FR (Completed) DE (Completed) AT (Completed) ES (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004012-31 Sponsor Protocol Number: RD 5130-009-07 Start Date*: 2009-07-06
    Sponsor Name:Derby Hospitals NHS Foundation Trust [...]
    1. Derby Hospitals NHS Foundation Trust
    2. The University of Nottingham-Research innovation services
    Full Title: The effects of improving oxygen concentration in the reduction of dialysis induced myocardial stunning – A pilot study
    Medical condition: Chronic renal failure patients who are receiving haemodialysis treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066623 Chronic haemodialysis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-005041-33 Sponsor Protocol Number: MAG111539 Start Date*: 2009-07-27
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Single-Blind Study of the Safety, Pharmacokinetics and Pharmacodynamics of Escalating Repeat Doses of GSK249320 in Patients With Stroke.
    Medical condition: Patients with Stroke.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-010975-26 Sponsor Protocol Number: ACROSS-08-01 Start Date*: 2009-07-16
    Sponsor Name:Associació Catalana per a la Recerca Oncológica i les seves implicacions Sanitáries i Socials
    Full Title: Estudio clínico abierto de fase II de panitumumab en combinación con quimioterapia FOLFIRI como tratamiento de segunda línea en sujetos con cáncer colorrectal metastásico que expresa KRAS no mutado...
    Medical condition: Cáncer colorrectal metastásico que expresa KRAS no mutado
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004764-39 Sponsor Protocol Number: CTBM100C2303E1 Start Date*: 2009-09-07
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A Phase III Open-Label Extension Study to Assess the Safety and Efficacy of Tobramycin Inhalation Powder after Manufacturing Process Modifications (TIPnew) in Cystic Fibrosis (CF) Subjects Who Comp...
    Medical condition: Pseudomonas aeruginosa infection in cystic fibrosis patients
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10021860 Infection pseudomonas aeruginosa LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) EE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-002680-13 Sponsor Protocol Number: GNRH-PES Start Date*: 2010-11-18
    Sponsor Name:Fundacion para la Investigación "Hospital Universitario Doctor Peset"
    Full Title: “Antagonistas de GnRH en el manejo del cuerpo lúteo hemorrágico. Estudio clínico y ecográfico de la luteolisis mediada por el cetrorelix”
    Medical condition: Luteolisis o regresión del cuerpo lúteo.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011117 Corpus luteum cyst or haematoma LLT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-007296-24 Sponsor Protocol Number: 08/01 Start Date*: 2009-01-21
    Sponsor Name:AISF - ASSOCIAZIONE ITALIANA PER LO STUDIO DEL FEGATO
    Full Title: Multicenter open-label, phase IIB study with 0.5 mg / day Entecavir (BARACLUDE ) in patients with positive HBsAg solid or hematologic malignancies undergoing chemotherapy (ChemET) (ChemET)
    Medical condition: Subject with new diagnosis of solid or haematological cancer in inactive carrier in chronic virus B infected patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008910 Chronic hepatitis B LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000789-22 Sponsor Protocol Number: ARX111418 Start Date*: 2009-05-04
    Sponsor Name:GlaxoSmithKline R & D
    Full Title: SAFE-AF: Safety of Fondaparinux in electric cardioversion of atrial fibrillation. An International, Multicentre, Randomised, Open, Controlled, Two-parallel Group, Phase II Study to Evaluate the Ef...
    Medical condition: Atrial fibrillation (AF)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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