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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 1,315 of 2,220.
    EudraCT Number: 2016-004302-33 Sponsor Protocol Number: TESTOPRIM Start Date*: 2017-04-07
    Sponsor Name:INSTITUTO DE INVESTIGACIÓN SANITARIA LA FE
    Full Title: Clinical effect of follicular preparation with testosterone in poor ovarian response: a randomized controlled clinical trial (TESTOPRIM)
    Medical condition: Infertility with Poor Ovarian Response
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004872 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-000040-13 Sponsor Protocol Number: 21011075118 Start Date*: 2009-02-11
    Sponsor Name:Medizinische Universität Innsbruck, Univ.-Klinik für Neurologie
    Full Title: Effects of recombinant human Erythropoietin on circulating and intramuscular endothelial progenitor cells, neovascularisation and oxidative metabolism of skeletal muscle in Friedreich’s Ataxia
    Medical condition: Friedreich's ataxia (FRDA) is the most common autosomal recessive neurodegenerativ disease (1:50 000) affecting the central and peripheral nervous system. Extraneural organs are also affected durin...
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-004099-26 Sponsor Protocol Number: 6.version,september2011 Start Date*: 2009-12-10
    Sponsor Name:Departmnet of nephrology
    Full Title: Randomised trial on combined effects of dual blockade of the renin angiotensin system and phosphate binding in diabetic and non-diabetic patients with impaired renal function.
    Medical condition: decreased renal function (CKD II-IV), creatinin clearance 15-90 ml/min
    Disease: Version SOC Term Classification Code Term Level
    18.0 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    18.0 10038359 - Renal and urinary disorders 10013231 Disorder kidney LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-005539-62 Sponsor Protocol Number: BGP-15-CLIN-07 Start Date*: 2021-03-04
    Sponsor Name:Mitochon Technologies Kft.
    Full Title: Phase II/III, multi-centre, double-blind, parallel assignment, randomized, placebo-controlled study to evaluate the preventive effect of BGP-15 on the hospitalisation of newly diagnosed COVID-19 pa...
    Medical condition: COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004848 10084355 COVID-19 virus test positive LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-003438-26 Sponsor Protocol Number: 161504 Start Date*: 2017-02-14
    Sponsor Name:Baxalta US Inc.
    Full Title: Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric Subjects with Primary Immunodeficiency Diseases
    Medical condition: Primary Immunodeficiency Disease (PIDD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10064859 Primary immunodeficiency syndrome PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) SE (Completed) DK (Completed) CZ (Completed) SK (Completed) FR (Completed) GR (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2021-000682-32 Sponsor Protocol Number: PAUF-I Start Date*: 2022-02-16
    Sponsor Name:Prestige Biopharma Limited
    Full Title: A First in human, Phase 1/2a, Multicentre, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of PBP1510 in Patients with Advanced/Metastatic Pancreatic Cancer
    Medical condition: Advanced and/or metastatic pancreatic adenocarcinoma.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001456-39 Sponsor Protocol Number: Tranex-AAA Start Date*: 2015-01-05
    Sponsor Name:IRCCS Ospedale San Raffaele
    Full Title: Tranexamic acid in major vascular surgery (Tranex-AAA)
    Medical condition: abdominal aortic aneurysm
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004866 10000054 Abdominal aortic aneurysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003177-34 Sponsor Protocol Number: CHDR1722 Start Date*: 2017-12-20
    Sponsor Name:Centre for Human Drug Research
    Full Title: A clinical study to assess the feasibility of measuring inhaled medication concentrations in exhaled breath condensate obtained from healthy volunteers and asthma patients and to assess the relatio...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-014824-40 Sponsor Protocol Number: ART621-290 Start Date*: 2009-11-03
    Sponsor Name:Arana Therapeutics Ltd
    Full Title: An open label follow on study to evaluate the long-term safety, tolerability and efficacy of ART621 following fortnightly administration for 48 weeks in patients with rheumatoid arthritis concomita...
    Medical condition: Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-004370-10 Sponsor Protocol Number: RUXO_LMMC-PRO_1401 Start Date*: 2014-03-21
    Sponsor Name:Grupo Español de Sindromes Mielodisplásicos (GESMD)
    Full Title: A phase II study of ruxolitinib (INCB018424) to evaluate efficacy and safety in Patients with Proliferative Chronic Myelomonocytic Leukemia (CMML)
    Medical condition: Proliferative Chronic Myelomonocytic Leukemia (CMML)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004864 10054350 Chronic myelomonocytic leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001301-23 Sponsor Protocol Number: APHP200387 Start Date*: 2020-04-10
    Sponsor Name:Assistance Publique - Hôpitaux de Paris
    Full Title: Efficacy of Addition of Naproxen in the Treatment of critically ill Patients Hospitalized for COVID-19 Infection / Enacovid Study
    Medical condition: COVID-19 Infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003005-10 Sponsor Protocol Number: IGR2012/1883 Start Date*: 2013-06-06
    Sponsor Name:Gustave Roussy
    Full Title: PHASE I-II STUDY OF VINBLASTINE IN COMBINATION WITH NILOTINIB IN CHILDREN, ADOLESCENTS, AND YOUNG ADULTS WITH REFRACTORY OR RECURRENT LOW-GRADE GLIOMA
    Medical condition: Children, adolescents and young adults with refractory or recurrent low-grade gliomas, and children, adolescents and young adults with neurofibromatosis type 1 and previously untreated low-grade g...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10065443 Malignant glioma PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10038111 Recurrent cancer PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10070308 Refractory cancer PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed) FR (Ongoing) NL (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004078-16 Sponsor Protocol Number: DOSCORT20092231 Start Date*: 2020-11-23
    Sponsor Name:Sahlgrenska University Hospital, Gothenburg
    Full Title: A dose-response study of markers of glucocorticoid action (DOSCORT)- A double-blind, randomized, two-period, two-dose, cross-over study in subjects with primary adrenal insufficiency
    Medical condition: Adrenal insufficiency e.g. Addison´s disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003638-28 Sponsor Protocol Number: 2015/576 Start Date*: 2015-09-30
    Sponsor Name:Aarhus University Hospital
    Full Title: ALOSTRA Alendronate treatment of osteoporosis in rheumatoid arthritis – indication and duration. A randomized, doubleblind, placebocontrolled multi-centre study to evaluate the effects of disconti...
    Medical condition: Rheumatoid arthritis and osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10031289 Osteoporosis, unspecified LLT
    20.0 100000004859 10039076 Rheumatoid arthritis and other inflammatory polyarthropathies LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021433-32 Sponsor Protocol Number: GCV2010 Start Date*: 2011-03-29
    Sponsor Name:INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE BELLVITGE(IDIBELL)
    Full Title: Individualización de las dosis de Ganciclovir/Valganciclovir por predicción bayesiana en pacientes trasplantados de órgano sólido infectados por citomegalovirus
    Medical condition: Enfermedad por citomegalovirus en trasplante de órgano sólido
    Disease: Version SOC Term Classification Code Term Level
    13 10011836 Infección por citomegalovirus LLT
    13 10058854 Viremia por citomegalovirus PT
    13 10011827 Infecciones por citomegalovirus HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-005407-40 Sponsor Protocol Number: 2011-425 Start Date*: 2013-02-07
    Sponsor Name:Thomas Bergholt
    Full Title: Peroperative Tranexamic acid as prophylaxis of bleeding related to benign hysterectomy - a randomized, placebo-controlled trial
    Medical condition: Bleeding related to benign hysterectomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10066252 Total vaginal hysterectomy LLT
    14.1 100000004865 10046913 Vaginal hysterectomy LLT
    14.1 100000004865 10021152 Hysterectomy (ovaries conserved) LLT
    14.1 100000004865 10057318 Total hysterectomy LLT
    14.1 100000004865 10059806 Ovariohysterectomy LLT
    14.1 100000004865 10000075 Abdominal hysterectomy LLT
    14.1 100000004865 10027801 Modified vaginal hysterectomy LLT
    14.1 100000004865 10023692 Laparoscopically assisted hysterectomy LLT
    14.1 100000004865 10044080 Total abdominal hysterectomy LLT
    14.1 100000004865 10042429 Subtotal hysterectomy LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-003421-28 Sponsor Protocol Number: 11-18 Start Date*: 2019-01-16
    Sponsor Name:St Patrick's Mental Health Services
    Full Title: Ketamine interleaved with electroconvulsive therapy for depression, a pragmatic randomised controlled pilot trial (KITE-Dep)
    Medical condition: Depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002204-84 Sponsor Protocol Number: I6T-MC-AMAG Start Date*: 2017-02-01
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 2, Multicenter, Randomized, Parallel-Arm, Placebo- Controlled Study of LY3074828 in Subjects with Active Crohn’s Disease (SERENITY)
    Medical condition: Crohn's Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) CZ (Completed) HU (Completed) AT (Completed) NL (Completed) PL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001605-23 Sponsor Protocol Number: HUA-COVID-19 Start Date*: 2020-05-29
    Sponsor Name:Basque Health Service
    Full Title: Effectiveness of the combined treatment with hydroxycloroquine and azithromycin vs lopinavir/ritonavir + hydroxycloroquine in hospitalized patients with confirmed COVID-19 infection
    Medical condition: Covid-19 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-001605-24 Sponsor Protocol Number: GWND19002 Start Date*: 2020-01-15
    Sponsor Name:GW Research Ltd
    Full Title: An open-label extension trial to investigate the long-term safety of cannabidiol oral solution (GWP42003-P, CBD-OS) in patients with Rett Syndrome
    Medical condition: Rett syndrome (RTT) [typical or atypical]
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10077709 Rett syndrome PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Prematurely Ended) IT (Ongoing)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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