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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44399   clinical trials with a EudraCT protocol, of which   7411   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,399 result(s) found. Displaying page 1,411 of 2,220.
    EudraCT Number: 2010-021979-85 Sponsor Protocol Number: 2009-323 Start Date*: 2017-06-01
    Sponsor Name:The Pediatric Clinics, The Juliane Marie Center, The Danish National Hospital "Rigshospitalet"
    Full Title: Danish: BCG vaccination og sygelighed blandt danske småbørn. En prospektivt, randomiseret, klinisk lægemiddelafprøvning. English: Bacille Calmette Guérin immunisation at birth and childhood morbidi...
    Medical condition: The study aims to test the hypothesis of the positive non-specific effect of BCG immunization at birth on early childhood morbidity in a high-income country.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054112 Hospitalisation LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-001059-37 Sponsor Protocol Number: AKST4290-221 Start Date*: 2019-06-21
    Sponsor Name:Alkahest, Inc.
    Full Title: Double-Blind, Randomized, Placebo-Controlled Trial of AKST4290 for Adjunctive Treatment of Mild to Moderate Bullous Pemphigoid
    Medical condition: Mild to Moderate Bullous Pemphigoid
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10006567 Bullous pemphigoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2020-000659-11 Sponsor Protocol Number: GLPG3970-CL-210 Start Date*: 2020-09-10
    Sponsor Name:Galapagos NV
    Full Title: A randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of GLPG3970, administered orally for 6 weeks in adult subjects...
    Medical condition: Ulcerative Colitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2018-002491-40 Sponsor Protocol Number: CLMB763X2202 Start Date*: 2019-04-03
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized patient-and-physician blinded, placebo-controlled, 24-week study to assess the safety, tolerability and efficacy of LMB763 in patients with diabetic nephropathy
    Medical condition: Diabetic Nephropathy
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10061835 Diabetic nephropathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-000175-33 Sponsor Protocol Number: D9484C00001 Start Date*: 2018-06-21
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase II, Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicentre, Three Month Duration Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy with Sodium Zirconium ...
    Medical condition: Heart Failure; Hyperkalaemia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) SK (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended) RO (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-000358-26 Sponsor Protocol Number: BETAF-RED Start Date*: 2022-05-11
    Sponsor Name:Institut d’Investigacions Biomèdiques August Pi i Sunyer
    Full Title: Safety, tolerability, and efficacy of a dose reduction strategy based on bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed HIV-infected adults.
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10008919 Chronic HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004977-23 Sponsor Protocol Number: DP312804 Start Date*: 2013-04-25
    Sponsor Name:SFJ LungCancer, Ltd.
    Full Title: ARCHER 1050: A RANDOMIZED, OPEN-LABEL, PHASE 3, EFFICACY AND SAFETY STUDY OF DACOMITINIB (PF 00299804) VERSUS GEFITINIB FOR THE FIRST LINE TREATMENT OF LOCALLY ADVANCED OR METASTATIC NON SMALL CELL...
    Medical condition: Non-Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10029514 Non-small cell lung cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2015-004210-26 Sponsor Protocol Number: 14/0647 Start Date*: 2016-11-22
    Sponsor Name:PRIMENT Clinical Trials Unit, UCL
    Full Title: A Phase IV double blind multi-site, individually randomised parallel group controlled trial investigating the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in pati...
    Medical condition: Depression
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000024331 10066555 Chronic depression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004607-39 Sponsor Protocol Number: 2013-00460739 Start Date*: 2014-04-11
    Sponsor Name:CUB Hopital Erasme
    Full Title: Safety of preoperative administration of hemin to reduce the risk of acute kidney injury after on-pump cardiac surgery: a pilot randomised study in double blind.
    Medical condition: Acute kidney injury which is associated with on-pump cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000982-38 Sponsor Protocol Number: 06/JM/119 Start Date*: 2007-06-14
    Sponsor Name:Greenpark Health Care Trust
    Full Title: Pain and mobility outcomes following patient controlled lumbar plexus block for primary joint arthroplasty
    Medical condition: Pain control after primary joint arthroplasty
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004794-13 Sponsor Protocol Number: VX16-809-122 Start Date*: 2020-05-01
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Phase 3, 2-part, Open-label Study to Evaluate the Safety and Pharmacokinetics of Lumacaftor/Ivacaftor in Subjects 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10011762 Cystic fibrosis PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-001003-38 Sponsor Protocol Number: RGHT000540 Start Date*: 2008-08-01
    Sponsor Name:The Royal Group of Hospitals, Belfast Trust
    Full Title: A study investigating rimonabant versus placebo in conjunction with a strict low-fat weight reduction diet in overweight and obese subjects: effects on glucose and lipid metabolism and cardiovascul...
    Medical condition: This study will investigate subjects who are overweight and obese with Body Mass Index >27kg/m2.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022489 Insulin resistance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013133-22 Sponsor Protocol Number: RGHT 000669 Start Date*: 2009-07-31
    Sponsor Name:Belfast Health & Social Care Trust
    Full Title: Comparison of the effects of single shot or continuous popliteal nerve block on postoperative outcome measures in patients undergoing operative repair of ankle fracture.
    Medical condition: POSTOPERATIVE ANALGESIA AFTER OPERATIVE REPAIR OF ANKLE FRACTURE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000852-24 Sponsor Protocol Number: 15/0552 Start Date*: 2017-08-23
    Sponsor Name:University College London (UCL)
    Full Title: A Phase I/II, Open label, Multicentre, Ascending Single Dose, Safety Study of a Novel Adeno-associated Viral Vector (FLT180a) in Patients With Haemophilia B
    Medical condition: Haemophilia B
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10018939 Haemophilia B (Factor IX) LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004720-37 Sponsor Protocol Number: Voluven_v1.0fr Start Date*: 2006-12-11
    Sponsor Name:CUB Hôpital Erasme, Department of Anesthesiology
    Full Title: Effect of Voluven on postoperative morbidity after gynaecological surgery
    Medical condition: Healthy female patients (American Society of Anaesthesiologists score I or II) programmed for elective gynaecological surgery and at least 18 years old
    Disease: Version SOC Term Classification Code Term Level
    8.1 10054182 Perioperative nausea and vomiting prophylaxis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006099-12 Sponsor Protocol Number: TSO-01 Start Date*: 2007-12-21
    Sponsor Name:Statens Serum Institut
    Full Title: Oral treatment of allergy with a non-pathogenic microorganism: A randomised clinical trial
    Medical condition: Allergic rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001723 Allergic rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-015840-40 Sponsor Protocol Number: LEVO/HK Start Date*: 2009-10-19
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: Chronic pain and mobility outcomes following primary hip arthroplasty. A comparison of intravenous morphine with lumbar plexus levobupivacaine.
    Medical condition: Acute and chronic pain following hip replacement surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-003835-30 Sponsor Protocol Number: Start Date*: 2005-05-26
    Sponsor Name:Belfast City Hospital
    Full Title: An open label, single centre, assessor blind pilot study comparing topical tacrolimus 0.1% and hydrocortisone ointment 1% in the treatment of flexural psoriasis
    Medical condition: flexural psoriasis
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-001398-19 Sponsor Protocol Number: Exposition-DCS Start Date*: 2011-06-27
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: D-cycloserine augmented exposure therapy in patients with agoraphobia
    Medical condition: agarophobia with or without panic disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001308-13 Sponsor Protocol Number: 301-PR-PRI-198 Start Date*: 2013-09-26
    Sponsor Name:LABORATORIOS LETI S.L.U
    Full Title: Biological standardization of Alternaria alternata allergen extract to determine the biological activity in histamine equivalent units (HEP).
    Medical condition: Allergy to Alternaria alternata
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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