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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 198 of 2,219.
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    EudraCT Number: 2009-014580-39 Sponsor Protocol Number: SP-B-02 Start Date*: 2010-01-05
    Sponsor Name:ALK-Abelló Arzneimittel GmbH
    Full Title: A multicentre randomised Phase II clinical pilot study to compare the pharmacodynamic efficacy and tolerability of the sublingual and the vestibular administration route for SLITonePLUS® Birch
    Medical condition: Birch pollen induced allergic rhinoconjunctivitis requiring treatment during the birch pollen season
    Disease: Version SOC Term Classification Code Term Level
    12.0 10001728 Allergic rhinoconjunctivitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014586-75 Sponsor Protocol Number: D0520C00020 Start Date*: 2009-12-21
    Sponsor Name:AstraZeneca AB
    Full Title: A 12-Week, Randomised, Double-Blind, Placebo-Controlled, Parallel Group, Multinational, Phase IIb Study to Evaluate the Efficacy and Safety of 60 mg AZD9668 Administered Orally Twice Daily to Subje...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    12.0 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) SK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-020809-33 Sponsor Protocol Number: EA-10-1-042 Start Date*: 2010-09-15
    Sponsor Name:Engelhard Arzneimittel GmbH & Co.KG
    Full Title: A phase IIa, single-center, randomized, observer-blind trial with intraindividual comparison of treated versus untreated to assess the wound healing efficacy of topical Tyrosur® Gel after experimen...
    Medical condition: Male or female subjects aged 18 years or older with healthy skin in the test area are eligible for this clinical trial
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036892 Promotion of wound healing LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020818-28 Sponsor Protocol Number: 10.0086 Start Date*: 2010-10-14
    Sponsor Name:St George's, University of London
    Full Title: A randomised, double-blind, placebo-controlled trial of metformin in chronic obstructive pulmonary disease (COPD) exacerbations: a pilot study
    Medical condition: Chronic obstructive pulmonary disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009026 Chronic obstructive airways disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016513-26 Sponsor Protocol Number: P/2009/88 Start Date*: 2009-12-17
    Sponsor Name:Centre Hospitalier Universitaire de Besançon
    Full Title: Etude pilote multicentrique randomisée en double aveugle des effets de la toxine botulique dans le traitement des vestibulodynies
    Medical condition: Vestibulodynies
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016517-14 Sponsor Protocol Number: SEQvsCONC Start Date*: 2010-09-22
    Sponsor Name:Dr. Javier Pérez Gisbert
    Full Title: ESTUDIO FASE IV, PROSPECTIVO, ALEATORIZADO Y COMPARATIVO ENTRE LA TERAPIA “SECUENCIAL” Y “CONCOMITANTE” PARA LA ERRADICACIÓN DE Helicobacter pylori EN LA PRÁCTICA CLÍNICA HABITUAL
    Medical condition: Infección por Helicobacter pylori
    Disease: Version SOC Term Classification Code Term Level
    12.0 10019377 Helicobacter pylori infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014835-19 Sponsor Protocol Number: CAIN457C2301 Start Date*: 2010-02-15
    Sponsor Name:Novartis Farmacéutica, S.A.
    Full Title: Estudio Fase III, multicéntrico, aleatorizado con doble enmascaramiento, controlado con placebo, de determinación de dosis y 24 semanas de duración, con el objetivo de evaluar el AIN457 frente a pl...
    Medical condition: Demostrar la eficacia y seguridad de AIN457 como terapia adyuvante en el tratamiento de la uveitis intermedia, uveitis posterior o panuveitis que precise inmunosupresión sistémica.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10022941 Iridocyclitis LLT
    9 10022557 Intermediate uveitis LLT
    9 10033687 Panuveitis LLT
    9 10036370 Posterior uveitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) DE (Prematurely Ended) GB (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-014854-14 Sponsor Protocol Number: CRFB002AGB10 Start Date*: 2009-11-17
    Sponsor Name:Novartis Pharmaceuticals UK Ltd
    Full Title: A phase II, open-label, multicentre, 12 month study to evaluate the efficacy and safety of ranibizumab (0.5 mg) in patients with choroidal neovascularization secondary to pathological myopia (PM)
    Medical condition: Choroidal neovascularisation (CNV) secondary to pathological myopia (PM)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10060823 Choroidal neovascularisation PT
    13.1 10015919 - Eye disorders 10067128 Myopic retinal degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014869-43 Sponsor Protocol Number: 2008_47/0928 Start Date*: 2009-12-21
    Sponsor Name:Centre Hospitalier Régional et Universitaire
    Full Title: Influence des acides gras polyinsaturés à longue chaîne n-3 sur l'expression des mucines dans la muqueuse nasale de patients atteints de mucoviscidose
    Medical condition: Mucoviscidose
    Disease: Version SOC Term Classification Code Term Level
    12.0 10028141 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002758-31 Sponsor Protocol Number: ECD01 Start Date*: 2006-12-22
    Sponsor Name:EPOPLUS GmbH & Co.KG
    Full Title: A randomized, double-blind, multi-centre, placebo-controlled, parallel-group study to examine the efficacy and safety of low dose Epoetin beta on wound healing in diabetes patients with foot ulcer
    Medical condition: wound healing in diabetes patients with foot ulcer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048037 Wound healing disturbance of LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-012222-36 Sponsor Protocol Number: 1.0 Start Date*: 2009-07-23
    Sponsor Name:Medizinische Universität Wien, Bernhard Gottlieb Universitätszahnklinik
    Full Title: Verification of an oro-antral communication after tooth extraction in the upper jaw. A Pilot-study
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012226-37 Sponsor Protocol Number: PIOMET-55 Start Date*: 2010-01-15
    Sponsor Name:HOSPITAL SANT JOAN DE DÉU
    Full Title: Ensayo clínico piloto de tratamiento con Pioglitazona+Flutamida+Metformina a Dosis Bajas versus Etinil-Estradiol + Acetato de Ciproterona como control, en Adolescentes con Hiperandrogenismo Ovárico...
    Medical condition: Hiperandrogenismo ovárico asociado a hiperinsulinismo.
    Disease:
    Population Age: Adolescents, Under 18 Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018919-16 Sponsor Protocol Number: TG-MV-010 Start Date*: 2010-06-28
    Sponsor Name:ThromboGenics NV
    Full Title: An Open-Label, Ascending- Exposure-Time, Single Center Trial to Evaluate the Pharmacokinetic Properties of Ocriplasmin (Generic Name of the Molecule Microplasmin) Intravitreal Injection in Subjects...
    Medical condition: Patients who require primary pars plana vitrectomy. A sample of vitreous will be taken at beginning of surgery for PK analysis.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10047644 Vitrectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018937-23 Sponsor Protocol Number: SD-QVAR Start Date*: 2010-05-31
    Sponsor Name:Medisch Spectrum Twente
    Full Title: The predictive value of the acute effect of beclomethasone on a mannitol challenge test for the outcome of lomgterm treatment with beclomethasone
    Medical condition: Exercise induced asthma / bronchoconstriction Asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015649 Exercise induced asthma LLT
    12.1 10003553 Asthma PT
    12.1 10066091 Bronchial hyperreactivity PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007115-87 Sponsor Protocol Number: LH-HCGPES Start Date*: 2008-02-08
    Sponsor Name:FUNDACION CV INVESTIGACION HOSPITAL DR PESET
    Full Title: ENSAYO CLÍNICO UNICÉNTRICO PARA VALORAR LA EFICACIA DE LA ADMINISTRACIÓN EXÓGENA DE LH EN FORMA DE HCG EN EL TRATAMIENTO DE LA DISFUNCIÓN SEXUAL FEMENINA POR DISMINUCIÓN DEL DESEO SEXUAL
    Medical condition: DISMINUCIÓN DEL DESEO SEXUAL FEMENINO EN MUJERES MENOPÁUSICAS
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007139-26 Sponsor Protocol Number: S075LBH501 Start Date*: 2008-04-17
    Sponsor Name:SENDO TECH
    Full Title: A phase II study of the histone deacetylase inhibitor Panobinostat (LBH589) in patients with advanced Small Cell Lung Cancer (SCLC)
    Medical condition: SCLC patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041070 Small cell lung cancer recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed) GR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016000-22 Sponsor Protocol Number: XM22-04 Start Date*: 2010-03-22
    Sponsor Name:BioGeneriX AG
    Full Title: Efficacy and safety of XM22 in patients with non small cell lung cancer receiving cisplatin / etoposide chemotherapy. A multinational, multicentre, randomised, double-blind placebo-controlled study
    Medical condition: Non Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    12.0 10025054 Lung cancer non-small cell stage IIIB LLT
    12.0 10025055 Lung cancer non-small cell stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-020026-17 Sponsor Protocol Number: 721001 Start Date*: 2010-08-23
    Sponsor Name:Baxter Innovations GmbH
    Full Title: AN OPEN-LABEL PHASE 3 STUDY TO ASSESS THE IMMUNOGENICITY AND SAFETY OF A VERO CELL-DERIVED TRIVALENT SEASONAL INFLUENZA VACCINE, STRAIN COMPOSITION 2010/2011, IN AN ADULT AND ELDERLY POPULATION
    Medical condition: To verify the immunogenicity and tolerance of a trivalent seasonal influenza vaccine with strain composition according to WHO/EU recommendation for the 2010/2011 season for yearly licensing applica...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022000 Influenza LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023981-27 Sponsor Protocol Number: Acti-SCIPE-001 Start Date*: 2011-03-08
    Sponsor Name:Activaero GmbH
    Full Title: An Open-Label Randomized Pilot Trial to Evaluate Tolerability, Safety and Applicability of AKITA Inhaled Budesonide Suspension in Children aged 3-11 years with Mild to Moderate Asthma
    Medical condition: Allergic or non-allergic mild to moderate asthma in children aged three to eleven years. Affected children need to suffer from mild to moderate asthma according to ATS definition at least for 6 mon...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003561 Asthma, unspecified LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-023987-41 Sponsor Protocol Number: 2010.2611 Start Date*: 2011-06-24
    Sponsor Name:University Medical Center Groningen
    Full Title: In vivo imaging of the effect of fulvestrant on availability of estrogen receptor binding sites in metastatic breast tumor lesions using [18F]FES-PET
    Medical condition: Estrogen Receptor-positive metastatic breast cancer patients that will be treated with fulvestrant
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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