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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 2 of 19.
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    EudraCT Number: 2012-004163-50 Sponsor Protocol Number: FIBHGM-ECNC002-2013(CETSEVOREM) Start Date*: 2014-04-29
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital
    Full Title: Comparative, randomized, double-blind clinical trial on end-tidal concentration of sevoflurane associated to remifentanil required for insertion of the Supreme Laryngeal Mask vs. Pro-Seal Laryngea...
    Medical condition: Patients requiring general anesthesia in whom the control of the airway is usually done with a supraglottic device.
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10018061 General anesthesia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004343-76 Sponsor Protocol Number: NMBA_ELDERLY2019ROCU_DOSES Start Date*: 2020-02-27
    Sponsor Name:Rigshospitalet
    Full Title: A single-blinded multicenter randomized interventional study of rocuronium 0.3 mg/kg, and 0.9 mg/kg comparing onset time, duration of action and effect on intubating conditions in elderly patients ...
    Medical condition: The aim of this study is to determine the onset time, duration of action and effect on intubating conditions after rocuronium 0.3 mg/kg and 0.9 mg/kg in patients with age ≥ 80 years.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10002321 Anesthesia LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-002329-20 Sponsor Protocol Number: SR052015 Start Date*: 2015-08-11
    Sponsor Name:University Hospitals Leuven
    Full Title: Xenon as an adjuvant to sevoflurane anaesthesia in children younger than four, undergoing interventional or diagnostic cardiac catheterization: a pilot study.
    Medical condition: Xenon anesthesia in children undergoing cardiac catherization
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004865 10018061 General anesthesia LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002021-35 Sponsor Protocol Number: ANR-1/14 Start Date*: 2014-09-23
    Sponsor Name:Fondazione IRCCS Istituto Nazionale dei Tumori
    Full Title: Decurarization After Thoracic Anesthesia - A prospective multicenter double-blind randomized trial comparing sugammadex vs neostigmine reversal after thoracic anesthesia
    Medical condition: Neuromuscular block is commonly adopted during general anesthesia to facilitate tracheal intubation, mechanical ventilation and surgical manipulation. At the end of anesthesia it very important to ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001091-18 Sponsor Protocol Number: FIBHGM-ECNC002-2011 Start Date*: 2011-09-20
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Gregorio Marañón
    Full Title: Comparative, randomized, double-blind clinical trial on 50 effective plasma concentration of propofol required for insertion of the Supreme Laryngeal Mask with or without association of remifenta...
    Medical condition: Patients requiring general anesthesia in whom the control of the airway is usually done with a supraglottic device.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10018061 General anesthesia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002848-24 Sponsor Protocol Number: IFT2019 Start Date*: 2020-03-06
    Sponsor Name:GIGA-Consciousness Thematic Unit, Anesthesia and Intensive Care Laboratory, Liege University
    Full Title: Brain functional signature of connected consciousness under general anesthesia using the isolated forearm technique
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001850-83 Sponsor Protocol Number: 2012/175/HP Start Date*: 2013-08-02
    Sponsor Name:CHU- Hôpitaux de Rouen
    Full Title: Adaptation to neonatal life after an anesthetic protocol using remifentanil for general anesthesia for caesarean section in a context of prematurity - REAGI Protocol (Remifentanil for General Anes...
    Medical condition: pregnant woman older than 18 years with an indication for caesarean section under general anesthesia in a context of prematurity.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10036585 - Pregnancy, puerperium and perinatal conditions 10026908 Maternal complications of pregnancy HLGT
    Population Age: Preterm newborn infants, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000965-19 Sponsor Protocol Number: 2019/374 Start Date*: 2019-08-26
    Sponsor Name:Helse Fonna
    Full Title: “Haemodynamic stability during induction of general anesthesia with propofol and remifentanil: A randomized, controlled, double-blind study comparing equipotent prophylactic doses of ephedrine, phe...
    Medical condition: Ephedrine, phenylephrine and norepinephrine are vasopressors used during anesthesia to treat hypotension. These agents raise blood pressure, but may have different effects on circulation as measure...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002399-25 Sponsor Protocol Number: Sevo-Des-2015-01 Start Date*: 2015-11-04
    Sponsor Name:Servicio de Anestesia Infantil. Hospital Universitario La Paz
    Full Title: CLINICAL TRIAL TO COMPARE THE INCIDENCE AND CHARACTERISTICS OF POSTOPERATIVE AGITATION IN PEDIATRIC PATIENTS AFTER ANESTHESIA WITH SEVOFLURANE OR DESFLURANE IN AMBULATORY SURGERY.
    Medical condition: AGITATION AFTER POSTOPERATIVE ANESTHESIA IN PEDIATRIC PATIENTS
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001886-33 Sponsor Protocol Number: MK-8616-076-00 Start Date*: 2012-10-30
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: Randomized, Controlled, Parallel Group, Double Blind Trial to Compare the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures Using a 2x2 Fact...
    Medical condition: Patients undergoing elective in-patient laparoscopic cholecystectomy procedures under general anesthesia with neuromuscular relaxation and active reversal of neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10018061 General anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) FI (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003716-12 Sponsor Protocol Number: RHNIA-001-2021 Start Date*: 2022-08-24
    Sponsor Name:Rigshospitalet
    Full Title: S-ketamine for cortical spreading depolarisation in patients with severe acute brain injury
    Medical condition: Severe acute brain injury caused by aneurysmal subarachnoid hemorrhage, spontaneous intracerebral hemorrhage or traumatic brain injury.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    21.1 100000004865 10070731 Electrocorticography LLT
    20.0 100000004852 10056389 Brain damage LLT
    21.0 100000004852 10019529 Hemorrhage brain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-024538-51 Sponsor Protocol Number: ssgt05 Start Date*: 2012-03-02
    Sponsor Name:Silvia Gil Trujillo
    Full Title: Study of the effects of pregabalin in postoperative pain control in general total intravenous anesthesia, general inhalation anesthesia and combined anesthesia after abdominal hysterectomy.
    Medical condition: The presence of acute postoperative pain remains a major cause of preoperative morbidity.The objective is to evaluate the analgesic efficacy of pregabalin in the postoperatory of abdominal hysterec...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005026-35 Sponsor Protocol Number: 35RC14_9853_DEXA-OP Start Date*: Information not available in EudraCT
    Sponsor Name:Centre Hospitalier Universitaire de Rennes
    Full Title: Study DEXA-OP. Can the dexaméthasone replace the kétoprofène in the strategy of per-operating multimodal analgesia in pediatric ambulatory surgery? A double-blind randomized comparative study.
    Medical condition: Per-operating analgesia, pediatric ambulatory surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10002321 Anesthesia LLT
    18.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001113-32 Sponsor Protocol Number: CNS7056-010 Start Date*: 2013-08-02
    Sponsor Name:PAION UK Limited
    Full Title: A Randomized, Single-blind Phase II Study Evaluating the Efficacy, Safety and Pharmacokinetics of Remimazolam in General Anesthesia in Adult Patients Undergoing Cardiac Surgery, Including Follow-up...
    Medical condition: Anaesthesia in adult patients undergoing cardiac surgery.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10021722 Induction and maintenance anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-019591-67 Sponsor Protocol Number: 1008032 Start Date*: 2010-06-01
    Sponsor Name:CHU de SAINT-ETIENNE
    Full Title: Pain assessment during general anesthesia : DOLANS Study
    Medical condition: perioperative analgesia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054799 Perioperative analgesia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001338-27 Sponsor Protocol Number: 2014-001338-27 Start Date*: 2014-06-19
    Sponsor Name:Helsinki University Central hospital
    Full Title: Influence of propofol and desfluran on the cerebral circulation and recovery after anesthesia
    Medical condition: Carotid endarterectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003810-96 Sponsor Protocol Number: 14-073 Start Date*: 2015-01-15
    Sponsor Name:RWTH Aachen University for the Medical Falculty, represented by Clinical Trial Center Aachen (CTC-A)
    Full Title: Emergence times and airway reactions in general laryngeal mask airway anesthesia: a randomized multicenter controlled trial
    Medical condition: Under investigation are first the time a patient needs to emerge from anesthesia (stating the date of birth) and second the occurrence of airway complications.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002803-81 Sponsor Protocol Number: TREX Start Date*: 2020-04-03
    Sponsor Name:IRCCS ISTITUTO GIANNINA GASLINI
    Full Title: Neurodevelopmental outcome after standard dose sevoflurane versus low-dose sevoflurane/dexmedetomidine/remifentanil anaesthesia in young children
    Medical condition: Children under the age of 2 years having surgery lasting at least 2 hours
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10018060 General anaesthesia PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-002214-13 Sponsor Protocol Number: IIBSP-OXI-2013-62 Start Date*: 2013-10-28
    Sponsor Name:Institut de Recerca de l?Hospital de la Santa Creu i Sant Pau ? IIB Sant Pau
    Full Title: Evaluation of oxidative stress associated with the administration of two different concentrations of oxygen for the maintenance of general anesthesia
    Medical condition: General anesthesia and oxidative stress
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002366-23 Sponsor Protocol Number: AD-V1-05252015 Start Date*: 2015-10-13
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Intensive Care and Pain Management
    Full Title: Goal-directed heart rate control during emergence from anesthesia using esmolol to attenuate myocardial injury in patients undergoing non-cardiac surgery
    Medical condition: myocardial damage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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