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Clinical trials for Terminal disease

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    684 result(s) found for: Terminal disease. Displaying page 2 of 35.
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    EudraCT Number: 2014-003496-29 Sponsor Protocol Number: I13034 Start Date*: 2014-10-24
    Sponsor Name:University Hospital, Limoges
    Full Title: Designing a Bayesian model of the plasma clearance of Calcium edetate de sodium, with a limited sampling strategy for the calculation of Glomerular Filtration Rate (GFR) and validity assessment com...
    Medical condition: Chronic Kidney Disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004857 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000606-75 Sponsor Protocol Number: IP-001-06 Start Date*: 2007-03-27
    Sponsor Name:IPERBOREAL PHARMA
    Full Title: Assessment of dialytic efficacy and tolerability of a peritoneal dialysis solution for notturnal exchange containing L-Carnitine in End Stage Renal Disease Patients (ESRD) in Automatised Peritonea...
    Medical condition: Utilization of a peritoneal solution containing L-Carnitine as osmotic agent in the treatment of ESRD patients with APD
    Disease: Version SOC Term Classification Code Term Level
    6.1 10038444 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012445-35 Sponsor Protocol Number: ALBLOCK-2 Start Date*: 2009-11-26
    Sponsor Name:Herlev Hospital
    Full Title: Aldosterone receptor blockade in patients with chronic kidney disease. Influence on arterial stiffness and kidney function.
    Medical condition: Chronic kidney disease, stages 3 and 4.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-006606-16 Sponsor Protocol Number: F003MN0307_1 Start Date*: 2008-07-11
    Sponsor Name:University of Wuerzburg
    Full Title: The Effects of Paricalcitol capsules on Inflammation (CRP levels) and Calcification regulation (fetuin-A levels) in CKD stage 5D patients
    Medical condition: Chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001033-12 Sponsor Protocol Number: 12020 Start Date*: 2020-10-13
    Sponsor Name:Niels Eske Bruun
    Full Title: PROPHYLACTIC ANTIBIOTIC TREATMENT IN END-STAGE KIDNEY DISEASE AND CENTRAL VENOUS CATHETER AS HEMODIALYSIS VASCULAR ACCESS
    Medical condition: Severe infection in patients end stage kidney disease and in hemodialysis with CVC as vascular asscess.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004857 10023420 Kidney failure chronic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002684-29 Sponsor Protocol Number: IP-001-21 Start Date*: 2023-07-10
    Sponsor Name:IPERBOREAL PHARMA S.R.L.
    Full Title: A Study of GlucoThera Plus for PeRitoneal DiAlysis in Children.
    Medical condition: End-Stage Renal Disease (ESRD)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10038359 - Renal and urinary disorders 10077512 End stage renal disease PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-006014-20 Sponsor Protocol Number: FARM6X822T Start Date*: 2009-01-19
    Sponsor Name:CONSORZIO MARIO NEGRI SUD
    Full Title: Effects of the dose of erythropoiesis stimulating agents on cardiac-cerebrovascular outcomes and quality of life in hemodialysis patients. The DOSe of Erythropoietins (DOSE) trial.
    Medical condition: End stage kidney disease and anemia, treated with hemodialysis for renal replacement therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003081-32 Sponsor Protocol Number: 1160.166 Start Date*: 2012-04-18
    Sponsor Name:Boehringer Ingelheim bv
    Full Title: An exploratory study to investigate the pharmacokinetics and effects of DABIgatran etexilate in patients with stable severe RENAL disease: DabiRenal
    Medical condition: Chronic kidney disease and coagulation
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022891 - Investigations 10060318 Anticoagulation drug level PT
    15.0 10038359 - Renal and urinary disorders 10038444 Renal failure chronic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-016362-85 Sponsor Protocol Number: ST1472-DM-09-005 Start Date*: 2009-11-09
    Sponsor Name:SIGMA-TAU
    Full Title: A PILOT, RANDOMIZED, SINGLE SITE, 3 PARALLEL ARMS, OPEN-LABEL STUDY IN PATIENTS ON CHRONIC DIALYSIS WITH END STAGE RENAL DISEASE (ESRD) TO EVALUATE THE ENHANCING EFFECT OF TWO DOSES OF THYMOSIN ALP...
    Medical condition: ZADAXIN ENHANCING EFFECT IN PATIENTS ON CHRONIC DIALYSIS WITH END STAGE RENAL DISEASE (ESRD) TREATED WITH EGG-DERIVED H1N1sw MONOVALENT INFLUENZA VACCINE
    Disease: Version SOC Term Classification Code Term Level
    12.1 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017619-14 Sponsor Protocol Number: EBP_TL_2009 Start Date*: 2010-03-26
    Sponsor Name:Medicinsk Forskningsafsnit, Holstebro
    Full Title: RENO- OG KREDSLØBSPROTEKTIV EFFEKT AF VITAMIN-D-ANALOG (PARICALCITOL) HOS PATIENTER MED MODERAT TIL SVÆR KRONISK NYREINSUFFICIENS
    Medical condition: The aim is to measure the effect of paricalcitol given orally in patients with moderate to severe chronic kidney diseases (CKD stage III-IV i.e. eGFR:15-59 ml/min) investigating vasoactive hormones...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002640-27 Sponsor Protocol Number: GED-301-01-11 Start Date*: 2011-07-14
    Sponsor Name:GIULIANI
    Full Title: A phase II multicenter, randomized, double-blind, controlled vs placebo, dose-finding study on the efficacy and safety of GED-0301, in patients with active Crohn‟s disease (Ileo-Colitis)
    Medical condition: ACTIVE CROHN'S DISEASE
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10021315 Ileitis terminal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004618-42 Sponsor Protocol Number: RISO06 Start Date*: 2006-09-25
    Sponsor Name:AZIENDA OSPEDALIERA PROVINCIALE DI LECCO
    Full Title: An evaluation of sodium removal with some peritoneal solutions a pilot study
    Medical condition: end stage renal disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10038444 Renal failure chronic LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005298-23 Sponsor Protocol Number: IP-002-05 Start Date*: 2007-03-12
    Sponsor Name:IPERBOREAL PHARMA
    Full Title: Efficiency of L-Carnitine-containing Peritoneal Dialysis Solutions for diurnal exchanges in CAPD Patients with ESRD on Glucose and Lipid Metabolisms. Randomized, Parallel Study Compared versus a St...
    Medical condition: Patients affected by End stage renal disease ESRD treated with Continuous Ambulatory Peritoneal Dialysis CAPD .
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038444 Renal failure chronic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-001388-23 Sponsor Protocol Number: PRO-RENAL-REG-062 Start Date*: 2004-11-09
    Sponsor Name:Baxter R&D Europe SCRL
    Full Title: A Study to Evaluate the Efficacy and Safety of Extraneal Physiological pH Compared with Current Extraneal in Patients Receiving Continuous Ambulatory Peritoneal Dialysis (CAPD).
    Medical condition: End Stage Renal Disease patients receiving continuous ambulatiry peritoneal dialysis (CAPD)
    Disease: Version SOC Term Classification Code Term Level
    6.1 10014646 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001200-23 Sponsor Protocol Number: CCFM 103/208 Start Date*: 2008-07-13
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: A Study to Evaluate the Effectiveness of Induced Diuresis with Matched Hydration Therapy Compared to Standard Overnight Hydration in the Prevention of Contrast Induced Nephropathy
    Medical condition: Patients with moderate to severe renal failure candidates to angiographic procedures at high risk for CIN
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009119 Chronic renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-001390-26 Sponsor Protocol Number: PRO-RENAL-REG-064 Start Date*: 2004-11-09
    Sponsor Name:Baxter R&D Europe SCRL
    Full Title: A Subjective Evaluation of Inflow Pain: Comparison of Extraneal to Extraneal Physiological pH
    Medical condition: Patients with End Stage Renal Disease (ESRD) undergoing peritoneal dialysis (PD) therapy and experiencing pain on infusion with Extraneal not related to the catheter or volume of dialysis fluid.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10014646 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005300-13 Sponsor Protocol Number: IP-003-05 Start Date*: 2007-05-29
    Sponsor Name:IPERBOREAL PHARMA
    Full Title: Efficiency of L-Carnitine-containing Peritoneal Dialysis Solutions for diurnal exchanges in diabetes type 2 CAPD patients with ESRD on glucose metabolism. Randomized, parallel study compared versus...
    Medical condition: Patients affected by End Stage Renal Disease (ESRD) treated with Continuous Ambulatory Peritoneal Dialysis (CAPD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038444 Renal failure chronic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005658-37 Sponsor Protocol Number: 2006-1 Start Date*: 2006-07-07
    Sponsor Name:Dpt. of Urology -K. Aarhus University Hospital
    Full Title: A randomized, multi-center study to assess the effect of Darbepoetin alfa (Aranesp®) for the treatment of anemia in patients with advanced hormone independent prostate cancer and anaemia
    Medical condition: In an open randomised, multi-center study to identify the haematopoietic response to Aranesp® (Darbepoetin 6,75 mcg/kg) administrated every fourth week compared to standard care of treatment in pat...
    Disease: Version SOC Term Classification Code Term Level
    6.1 10038444 PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-006168-30 Sponsor Protocol Number: RLH_Pentoxifylline_Dec2011 Start Date*: 2013-01-08
    Sponsor Name:R&D, Barts and The London NHS Trust
    Full Title: PEntoxifylline in Anaemia Resistant to erythropoietin (PEAR)
    Medical condition: We shall study patients with renal failure on dialysis. We shall particularly focus on patients with evidence of erythopoeitin stimulating agent (ESA) resistance.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020114-29 Sponsor Protocol Number: IGFHD1-2010 Start Date*: 2010-07-13
    Sponsor Name:Department of Nephrology
    Full Title: Insulin-like growth factor in hemodialysis patients
    Medical condition: This project aims to investigate whether the anabolic potentials of insulin may be used to reverse the catabolic effects of hemodialysis in non-diabetic patients with end-stage renal failure. Thus...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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