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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,352 result(s) found. Displaying page 2,104 of 2,218.
    EudraCT Number: 2010-021396-81 Sponsor Protocol Number: LINES Start Date*: 2011-06-15
    Sponsor Name:INSTITUTO DE INVESTIGACIÓN SANITARIA LA FE DE VALENCIA
    Full Title: European Low and Intermediate Risk Neuroblastoma
    Medical condition: INTERMEDIATE AND LOW RISK NEUROBLASTOMA
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing) DK (Completed) AT (Completed) IT (Completed) BE (Completed) NO (Completed) FR (Completed) IE (Completed) SE (Completed) PT (Completed) LT (Completed) GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004679-11 Sponsor Protocol Number: 0604 Start Date*: 2020-04-21
    Sponsor Name:Division of Thoracic and Hyperbaric Surgery, Medical University Graz
    Full Title: Hyperbaric Oxygenation (HBO) in traumatic spinal cord injury - prospective study with 100 patients.
    Medical condition: We want to investigate the effect of hyperbaric oxygen therapy on the neurological and clinical outcome following traumatic injury of the spinal cord.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001806-94 Sponsor Protocol Number: VACC-IR Start Date*: 2006-05-22
    Sponsor Name:Hôpital Erasme
    Full Title: Comparison of the efficacy of pneumococcal and tetanus vaccination between hemodialysis patients and renal tranpslant recipients treated with Mycophenolic acid(VACC-IR) study.
    Medical condition: Patients on dialysis and waiting for renal transplant and renal translanted patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017137-22 Sponsor Protocol Number: 190178 Start Date*: 2013-04-16
    Sponsor Name:Klinische Abteilung für Thorax -u. Hyperbare Chirurgie, Medizinische Universität Graz
    Full Title: Clinical course after substitution of Vitamin-D deficiency in patients with lung cancer or oesophageal carcinoma. Double blind randomised prospective, placebo-controlled study.
    Medical condition: Patients admitted for treatment on a general thoracic surgery division with the following conditions: Lung cancer Esophageal cancer Cancer of the gastroesophageal junction (GEJ)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002963-92 Sponsor Protocol Number: CLRX712A12201 Start Date*: 2020-02-05
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, subject and investigator blinded study investigating the safety, tolerability and preliminary efficacy of 8-week treatment with intra-articular LRX712 to regenerat...
    Medical condition: Cartilage injuries
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005399-15 Sponsor Protocol Number: CEFFOS7 Start Date*: 2010-03-10
    Sponsor Name:Medizinische Universität Graz - Abteilung für Thorax- und Hyperbare Chirurgie
    Full Title: Penetration of Cubicin® and Fosfomycin® into skeletal muscle and subcutaneous adipose tissue of necrotizing soft tissue infections, measured by in-vivo microdialysis
    Medical condition: A group of adult male or female patients with documented necrotizing soft tissue infection who must be subjected to undergo intravenous antimicrobial therapy with broad spectrum antibiotics.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020939-40 Sponsor Protocol Number: MD-Neo-Pilot Start Date*: 2010-07-28
    Sponsor Name:Medizinische Universität Wien,Univ.Klinik f.Kinder-u.Jugendheilkunde
    Full Title: Pilot Trial: Feasibility of Microdialysis for Pharmacokinetic Studies in Neonatal Patients
    Medical condition: The present pilot study intends to establish the logistics of MD measurements of antibiotics in subcutaneous tissue of neonatal intensive care patients. Antibiotic serum levels will be measured in ...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001271-38 Sponsor Protocol Number: LT 2004 09 Start Date*: 2006-06-23
    Sponsor Name:Our Lady's Hospital for Sick Children
    Full Title: Intensified pre-operative chemotherapy and radical surgery for HIGH RISK HEPATOBLASTOMA SIOPEL 4
    Medical condition: Hepatoblastoma
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002434-38 Sponsor Protocol Number: 197319731973 Start Date*: 2006-07-14
    Sponsor Name:Dr catenacci fabrice/ quartier operatoire
    Full Title: BLOC DU PLEXUS LOMBOSACRE PAR VOIE PARAVERTEBRALE : EVA-LUATION POUR LA PRATIQUE QUOTIDIENNNE
    Medical condition: Nous évaluons une technique d’anesthésie locorégionale permettant la réalisation d’une anesthésie du membre inférieur pour les chirurgies de la hanche au pied. Par une seule ponction transcutanée p...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005017-23 Sponsor Protocol Number: FM-14-B02 Start Date*: 2016-01-26
    Sponsor Name:Fondazione Michelangelo - Avanzamento dello studio e cura dei tumori
    Full Title: Neo-Adjuvant study with the PDL1-directed antibody in Triple Negative, Early High-Risk and Locally Advanced Breast Cancer undergoing treatment with nab-paclitaxel and carboplatin
    Medical condition: Women with a diagnosis of invasive unilateral, early high-risk and locally advanced or inflammatory, triple negative (HER2-negative and ER-negative and PgRnegative) breast cancer of high proliferat...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006200 Breast cancer stage II PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006196 Breast cancer NOS stage III LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006195 Breast cancer NOS stage II LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006201 Breast cancer stage III PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10075566 Triple negative breast cancer PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10021975 Inflammatory breast cancer stage III LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) AT (Completed) ES (Completed) IE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004406-26 Sponsor Protocol Number: A/100/0402 Start Date*: 2007-11-26
    Sponsor Name:AVAX Technologies Inc.
    Full Title: Comparison of M-Vax plus Low Dose Interleukin-2 versus Placebo Vaccine plus Low Dose Interleukin-2 in patients with Stage IV Melanoma
    Medical condition: Melanoma Stage IV MedDRA : 10025671
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004034-11 Sponsor Protocol Number: GR-OG-279239-04 Start Date*: 2022-05-18
    Sponsor Name:Genera Research Ltd
    Full Title: A randomized, evaluator-blinded, dose-ranging, proof of concept study of efficacy, safety and tolerability of Osteogrow-C (rhBMP6 delivered in autologous blood coagulum [ABC] supplemented with sy...
    Medical condition: The treatment of non-union of the tibia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10017088 Fracture nonunion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-003223-20 Sponsor Protocol Number: TEMO-PK6 Start Date*: 2007-08-01
    Sponsor Name:Cliniques Universitaires St Luc - UCL
    Full Title: Temocillin use in intensive care units: A Pharmacokinetic study of 6g per day in conventional administration vs. continuous infusion
    Medical condition: Patients will be eligible for participation in the study if they : 1. are hospitalized in an intensive care unit 2. have an abdominal or a pulmonary infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056519 Abdominal infection PT
    9.1 10052110 Bronchopulmonary infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004869-25 Sponsor Protocol Number: GORTEC 2008-03 Start Date*: 2008-12-31
    Sponsor Name:Groupe d'Oncologie Radiothérapie Tête Et Cou (GORTEC)
    Full Title: Étude de phase II évaluant l’association cetuximab, docétaxel et cisplatine en première ligne de traitement des carcinomes épidermoïdes de la tête et du cou métastatiques ou récidivants
    Medical condition: L’addition de cetuximab au docétaxel et au cisplatine dans le traitement des cancers ORL métastatiques ou récidivants se justifie par la mortalité encore importante dans cette indication, les donné...
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004193-18 Sponsor Protocol Number: LEVOS-001 Start Date*: 2017-02-16
    Sponsor Name:Semmelweis University, Heart and Vascular Center
    Full Title: Effect of repetitive levosimendan treatment on clinical outcomes of chronic heart failure patients: focus on optimal patient selection based on novel cardiac biomarkers.
    Medical condition: A total of 80 symptomatic patients with severe ischaemic or non-ischaemic cardiomyopathy will be enrolled in the study. Those, who were implanted a device and proved to be non-responders or low res...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006558-17 Sponsor Protocol Number: Start Date*: 2010-01-21
    Sponsor Name:cliniques universitaire de mont godinne
    Full Title:
    Medical condition: major depression
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004144-22 Sponsor Protocol Number: BORLEUWT01 Start Date*: 2012-01-12
    Sponsor Name:Institut Jules Bordet - Université Libre de Bruxelles
    Full Title: A Phase I/II study to assess the safety and immunogenicity of WT1-A10 + AS01B Antigen-Specific Cancer Immunotherapeutic (ASCI) combined with infusions of ex vivo regulatory T cells depleted T lymph...
    Medical condition: For adult patients with WT1-positive Acute Myeloid Leukemia (AML) in CR1 (for high risk patients) or in CR2 or CR3 who are not eligible for allogeneic stem cell transplantation (SCT)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005474-38 Sponsor Protocol Number: YZIRIT Start Date*: 2012-03-08
    Sponsor Name:Institut Jules Bordet
    Full Title: 89Zr-Rituximab PET/CT-Imaging and Dosimetry and 90Y-Rituximab Radioimmunotherapy in CD20+ B-Cell lymphoma
    Medical condition: CD20 positive Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10003902 B-cell lymphoma recurrent PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002673-21 Sponsor Protocol Number: 35RC17_8841_EFFICACI Start Date*: 2018-09-04
    Sponsor Name:Centre Hospitalier Universitaire de Rennes
    Full Title: EFFICACI : EFFicacy of intravenous Infliximab versus vedolizumab after failure of subCutaneous Anti-TNF in patients with UlCerative colitis : A double blinded Randomized Clinical Trial.
    Medical condition: Ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004410-42 Sponsor Protocol Number: C11-09 Start Date*: 2012-11-26
    Sponsor Name:Inserm
    Full Title: A phase I/II, open labeled, monocentric study of direct intracranial administration of a replication deficient adeno-associated virus gene transfer vector serotype rh.10 expressing the human ARSA c...
    Medical condition: Early onset forms of MLD
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    14.1 10010331 - Congenital, familial and genetic disorders 10067609 Metachromatic leukodystrophy PT
    14.1 10027433 - Metabolism and nutrition disorders 10027433 Metabolism and nutrition disorders SOC
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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