Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44352 clinical trials with a EudraCT protocol, of which 7379 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
How to search [pdf]

Advanced Search:

Search tools

Select Country:	Select Age Range:
Select Trial Status:	Select Trial Phase:
Select Gender:
Select Date Range: to
Select Rare Disease:
IMP with orphan designation in the indication
Orphan Designation Number:
Results Status:
Clear advanced search filters

Trials with a EudraCT protocol (44,352)
Paediatric studies in scope of Art45 of the Paediatric Regulation (18,700)

44,352 result(s) found. Displaying page 214 of 2,218.

EudraCT Number: 2009-017901-12

Sponsor Protocol Number: LYO_2009-09

Start Date*: 2010-02-26

Sponsor Name:LYOCENTRE

Full Title: Etude de l’efficacité et de la tolérance du traitement par la culture totale lyophilisée de lactobacillus casei variété rhamnosus (Lcr35 Lc) administré par voie vaginale dans la prévention de réci...

Medical condition: vaginose bactérienne récidivante

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.1		10004055	Bacterial vaginosis	LLT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: FR (Ongoing)

Trial results: (No results available)

EudraCT Number: 2008-002244-42

Sponsor Protocol Number: VITD1/08

Start Date*: 2009-07-03

Sponsor Name:King's College London [...]

Full Title: Does 1-alpha,25-dihydroxyvitamin D3 (calcitriol) enhance corticosteroid activity in steroid refractory asthma? A randomised control trial to test whether active vitamin D can improve the clinica...

Medical condition: Asthma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.0	10038738 - Respiratory, thoracic and mediastinal disorders	10003553	Asthma	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2007-002969-12

Sponsor Protocol Number: A6181094

Start Date*: 2007-12-04

Sponsor Name:Pfizer Inc. - 235 East 42nd Street - New York - 10017

Full Title: A PHASE 3 STUDY OF SU011248 IN COMBINATION WITH PACLITAXEL VERSUS BEVACIZUMAB WITH PACLITAXEL IN THE FIRST-LINE ADVANCED DISEASE SETTING IN PATIENTS HAVING BREAST CANCER

Medical condition: Locally Recurrent or Metastatic Breast Cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10006198	Breast cancer recurrent	LLT
	9.1		10027475	Metastatic breast cancer	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) ES (Prematurely Ended) IT (Completed)

Trial results: View results

EudraCT Number: 2007-002976-32	Sponsor Protocol Number: unknown	Start Date*: 2007-09-06
Sponsor Name:TIPharma
Full Title: COBRA-light study, an open randomised trial comparing a modified COBRA therapy with the COBRA therapy according to BeSt in early rheumatoid arthritis.
Medical condition: Patients with early rheumatoid arthritis wil be treated with a combination therapy: COBRA according to BEST or a modified COBRA schedule (COBRA-light).
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: NL (Ongoing)
Trial results: (No results available)

EudraCT Number: 2007-002983-89

Sponsor Protocol Number: BRD 07/3-Y

Start Date*: 2007-10-12

Sponsor Name:Centre Hospitalier Universitaire de Nantes

Full Title: Intérêt de l’administration continue de ropivacaïne à l’aide du Pain – Buster™ dans la chirurgie des lambeaux microanastomosés de latissimus dorsi et de serratus

Medical condition: Analgésie postopératoire suite à une chirurgie des lambeaux microanastomosés de latissimus dorsi et de serratus

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10024037	Latissimus dorsi flap	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Ongoing)

Trial results: (No results available)

EudraCT Number: 2009-013537-22	Sponsor Protocol Number: NeoSuga_1.0	Start Date*: 2009-08-11
Sponsor Name:Klaus Olkkola
Full Title: Clinical safety of neostigmine or sugammadex to reverse rocuronium-induced neuromuscular block Rokuronilla aikaansaadun lihasrelaksaation kumoaminen neostigmiinilla tai sugammadeksilla: kliininen t...
Medical condition: Sellainen leikkaushoitoa vaativa sairaus, jossa leikkauksen arvioitu kesto on vähintään 30 min
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FI (Completed)
Trial results: (No results available)

EudraCT Number: 2009-013543-11	Sponsor Protocol Number: 2009057	Start Date*: 2009-10-19
Sponsor Name:James Cook University Hospital
Full Title: A comparison of nausea with two routine ways of managing low blood pressure after delivery of the baby during spinal anaesthesia for Caesarean section.
Medical condition: We are investigating nausea associated with hypotension caused by spinal anaesthesia in healthy women undergoing elective Caesarean section. NICE recommend phenylephrine in this population. The aim...
Disease:
Population Age: Adults		Gender: Female
Trial protocol: GB (Prematurely Ended)
Trial results: (No results available)

EudraCT Number: 2009-014137-25

Sponsor Protocol Number: VARDENAFIL&DIABETES

Start Date*: 2009-12-15

Sponsor Name:Unita` Operativa di Endocrinologia e Malattie del Metabolismo

Full Title: Monitoring of endothelial dysfunction during chronic administration of vardenafil in patients with type 2 diabetes mellitus: A longitudinal, randomised, placebo-controlled, double blind, phase II b...

Medical condition: patients affected by type 2 Diabetes mellitus and affected by mild or severe ED

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.0		10045248	Type II diabetes mellitus with other specified manifestations	LLT

Population Age: Adults

Gender: Male

Trial protocol: IT (Ongoing)

Trial results: (No results available)

EudraCT Number: 2009-014268-20

Sponsor Protocol Number: VZV01

Start Date*: 2009-12-24

Sponsor Name:Erasmus MC

Full Title: VZV vaccination to prevent herpes zoster after transplantation

Medical condition: Herpes Zoster

Disease:	Version	SOC Term	Classification Code	Term	Level
	12.0		10019974	Herpes zoster	LLT
	12.0		10036897	Prophylactic vaccination	LLT
	12.0		10023438	Kidney transplant	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2008-007012-15

Sponsor Protocol Number: CYT013-IL1bQb 01

Start Date*: 2009-05-28

Sponsor Name:Cytos Biotechnology AG

Full Title: A Two-Stage Randomized Placebo-controlled Ascending Dose Phase I/ IIa Study to Evaluate Safety, Tolerability, Pharmacodynamic Effects and Preliminary Efficacy of an Anti-Interleukin 1 beta Vaccine ...

Medical condition: adult patients with type 2 diabetes mellitus

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10012601	Diabetes mellitus	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2008-007019-33

Sponsor Protocol Number: RES.I.ST. EXPERIENCED

Start Date*: 2008-12-24

Sponsor Name:FONDAZIONE CENTRO EMOFILIA E TROMBOSI ANGELO BIANCHI BONOMI

Full Title: IMMUNE TOLERANCE INDUCTION STUDY IN PATIENTS WITH SEVERE TYPE A HAEMOPHILIA WITH INHIBITOR AFTER FAILURE OF A PREVIOUS INDUCTION OF IMMUNE TOLERANCE WITH FVIII CONCENTRATES WITHOUT VON WILLEBRAND F...

Medical condition: SEVERE TYPE A HAEMOPHILIA

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10010432	Congenital deficiency of other clotting factors	LLT

Population Age: Children, Adolescents, Under 18, Adults, Elderly

Gender: Male

Trial protocol: IT (Ongoing) ES (Prematurely Ended) GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2009-010668-40

Sponsor Protocol Number: 1237.5

Start Date*: 2011-07-29

Sponsor Name:Boehringer Ingelheim bv [...]

Full Title: A randomised, double-blind, parallel group study to assess the efficacy and safety of 52 weeks of once daily treatment of orally inhaled tiotropium + olodaterol fixed dose combination (2.5 μg / 5 μ...

Medical condition: Patients with Chronic Obstructive Pulmonary Disease (COPD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	13.1	10038738 - Respiratory, thoracic and mediastinal disorders	10010952	COPD	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Completed) FI (Completed) PT (Completed) SI (Completed) CZ (Completed) DE (Completed) HU (Completed) DK (Completed) EE (Completed) IT (Completed)

Trial results: View results

EudraCT Number: 2009-012270-12

Sponsor Protocol Number: BC22419

Start Date*: 2010-05-21

Sponsor Name:F. Hoffmann-La Roche Ltd.

Full Title: Effects of 150 μg aleglitazar on renal function in patients with Type 2 diabetes and moderate renal impairment, as compared to Actos®

Medical condition: Type 2 diabetes with moderate renal function impairment

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.0		10007649	Cardiovascular disorder	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) HU (Completed) SK (Completed) IT (Completed)

Trial results: View results

EudraCT Number: 2007-005491-14

Sponsor Protocol Number: P05225

Start Date*: 2008-07-16

Sponsor Name:SCHERING-PLOUGH

Full Title: TEMOZOLOMIDE IN METASTATIC BREAST CANCER PATIENTS AT HIGH RISK OF BRAIN RECURRENCE: IMPACT ON THE INCIDENCE OF BRAIN METASTASES

Medical condition: pazienti

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10055113	Breast cancer metastatic	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: View results

EudraCT Number: 2009-018092-14

Sponsor Protocol Number: CRAD001RDE35T

Start Date*: Information not available in EudraCT

Sponsor Name:Krankenhaus Nordwest GmbH

Full Title: A randomized, double-blind, multi-center phase III study evaluating paclitaxel with and without RAD001 in patients with gastric carcinoma who have progressed after therapy with a fluoropyrimidine/p...

Medical condition: advanced (i.e. inoperable, recurrent or metastatic) gastric cancer or adenocarcinoma of the esophagogastric junction

Disease:	Version	SOC Term	Classification Code	Term	Level
	18.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10001150	Adenocarcinoma gastric	PT
	18.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10026104	Malignant neoplasm of lower third of esophagus	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2009-018101-52	Sponsor Protocol Number: V72P13E2	Start Date*: 2010-05-18
Sponsor Name:Novartis Vaccines and Diagnostics S.r.l
Full Title: Title of the trial: A Phase 3, Open-Label, Multi-Center, Extension Study of V72P13E1 to Assess Antibody Persistence at One Year After a Fourth Dose Boost or Two Catch-Up Doses of Novartis Meningoco...
Medical condition: Groups 1a, 1b, 2a and 2b: From the last study visit in V72P13E1 to the start of the study V72P13E2 (Day 1):assessment of immunogenicity or safety Group 3: From birth to the start of the study V7...
Disease:
Population Age: Children, Under 18		Gender: Male, Female
Trial protocol: FI (Completed) CZ (Completed)
Trial results: View results

EudraCT Number: 2010-019014-25	Sponsor Protocol Number: Istrokepilot	Start Date*: 2010-07-27
Sponsor Name:Karolinska University Hospital
Full Title: A PROSPECTIVE, RANDOMISED, OPEN, BLINDED EVALUATION, ASCENDING-DOSE, PILOT TRIAL OF IMATINIB IN ACUTE ISCHAEMIC STROKE (I-STROKE/pilot)
Medical condition: Acute ischaemic stroke
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: SE (Ongoing)
Trial results: (No results available)

EudraCT Number: 2007-004429-45

Sponsor Protocol Number: CHORUS

Start Date*: 2008-02-04

Sponsor Name:Medical Research Council

Full Title: A randomised trial to determine the impact of timing of surgery and chemotherapy in newly diagnosed patients with advanced epithelial ovarian, primary peritoneal or fallopian tube carcinoma

Medical condition: Women with newly diagnosed, suspected, advanced (compatible with FIGO stage III/IV) ovarian, primary peritoneal or fallopian tube cancer who fulfil other entry criteria, with clinical and/or imagin...

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10033131	Ovarian carcinoma	LLT
	9.1		10052171	Peritoneal carcinoma	LLT
	9.1		10016180	Fallopian tube cancer	LLT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2009-017600-89	Sponsor Protocol Number: FC/hulp003	Start Date*: 2010-06-24
Sponsor Name:Asociación para la investigación de Nefrología Infantil
Full Title: Ensayo intrapaciente de biodisponibilidad relativa de dos formulaciones de tacrolimus: Prograf (comprimidos de liberación normal) y Advagraf (comprimidos de liberación sostenida) en niños trasplant...
Medical condition: Transplante renal
Disease:
Population Age: Children, Adolescents, Under 18		Gender: Male, Female
Trial protocol: ES (Ongoing)
Trial results: (No results available)

EudraCT Number: 2009-017620-11

Sponsor Protocol Number: KINURA-2

Start Date*: 2011-06-14

Sponsor Name:Scheper Ziekenhuis

Full Title: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij patiënten met colorectaal carcinoom.

Medical condition: Colorectal cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.1		10010036	Colorectal carcinoma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Ongoing)

Trial results: (No results available)

Subscribe to this Search
To subscribe to the RSS feed for this search click here

. This will provide an RSS feed for clinical trials matching your search that have been added or updated in the last 7 days.

Download Options:
Number of Trials to download:

Download Content:

Download Format:


Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.

Query did not match any studies.

For support, Contact us.

The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

European Medicines Agency © 1995-Sat Aug 02 09:41:56 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands

Austria
Belgium
Bulgaria
Croatia
Cyprus
Czechia
Denmark
Estonia
Finland
France
Germany
Greece
Hungary
Iceland
Ireland
Italy
Latvia
Liechtenstein
Lithuania
Luxembourg
Malta
Netherlands
Norway
Poland
Portugal
Romania
Slovakia
Slovenia
Spain
Sweden
United Kingdom
Outside EU/EEA