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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 214 of 2,219.
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    EudraCT Number: 2009-012270-12 Sponsor Protocol Number: BC22419 Start Date*: 2010-05-21
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: Effects of 150 μg aleglitazar on renal function in patients with Type 2 diabetes and moderate renal impairment, as compared to Actos®
    Medical condition: Type 2 diabetes with moderate renal function impairment
    Disease: Version SOC Term Classification Code Term Level
    12.0 10007649 Cardiovascular disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005491-14 Sponsor Protocol Number: P05225 Start Date*: 2008-07-16
    Sponsor Name:SCHERING-PLOUGH
    Full Title: TEMOZOLOMIDE IN METASTATIC BREAST CANCER PATIENTS AT HIGH RISK OF BRAIN RECURRENCE: IMPACT ON THE INCIDENCE OF BRAIN METASTASES
    Medical condition: pazienti
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055113 Breast cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-018092-14 Sponsor Protocol Number: CRAD001RDE35T Start Date*: Information not available in EudraCT
    Sponsor Name:Krankenhaus Nordwest GmbH
    Full Title: A randomized, double-blind, multi-center phase III study evaluating paclitaxel with and without RAD001 in patients with gastric carcinoma who have progressed after therapy with a fluoropyrimidine/p...
    Medical condition: advanced (i.e. inoperable, recurrent or metastatic) gastric cancer or adenocarcinoma of the esophagogastric junction
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10001150 Adenocarcinoma gastric PT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026104 Malignant neoplasm of lower third of esophagus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018101-52 Sponsor Protocol Number: V72P13E2 Start Date*: 2010-05-18
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l
    Full Title: Title of the trial: A Phase 3, Open-Label, Multi-Center, Extension Study of V72P13E1 to Assess Antibody Persistence at One Year After a Fourth Dose Boost or Two Catch-Up Doses of Novartis Meningoco...
    Medical condition: Groups 1a, 1b, 2a and 2b: From the last study visit in V72P13E1 to the start of the study V72P13E2 (Day 1):assessment of immunogenicity or safety Group 3: From birth to the start of the study V7...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2010-019014-25 Sponsor Protocol Number: Istrokepilot Start Date*: 2010-07-27
    Sponsor Name:Karolinska University Hospital
    Full Title: A PROSPECTIVE, RANDOMISED, OPEN, BLINDED EVALUATION, ASCENDING-DOSE, PILOT TRIAL OF IMATINIB IN ACUTE ISCHAEMIC STROKE (I-STROKE/pilot)
    Medical condition: Acute ischaemic stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004429-45 Sponsor Protocol Number: CHORUS Start Date*: 2008-02-04
    Sponsor Name:Medical Research Council
    Full Title: A randomised trial to determine the impact of timing of surgery and chemotherapy in newly diagnosed patients with advanced epithelial ovarian, primary peritoneal or fallopian tube carcinoma
    Medical condition: Women with newly diagnosed, suspected, advanced (compatible with FIGO stage III/IV) ovarian, primary peritoneal or fallopian tube cancer who fulfil other entry criteria, with clinical and/or imagin...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033131 Ovarian carcinoma LLT
    9.1 10052171 Peritoneal carcinoma LLT
    9.1 10016180 Fallopian tube cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017600-89 Sponsor Protocol Number: FC/hulp003 Start Date*: 2010-06-24
    Sponsor Name:Asociación para la investigación de Nefrología Infantil
    Full Title: Ensayo intrapaciente de biodisponibilidad relativa de dos formulaciones de tacrolimus: Prograf (comprimidos de liberación normal) y Advagraf (comprimidos de liberación sostenida) en niños trasplant...
    Medical condition: Transplante renal
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017620-11 Sponsor Protocol Number: KINURA-2 Start Date*: 2011-06-14
    Sponsor Name:Scheper Ziekenhuis
    Full Title: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij patiënten met colorectaal carcinoom.
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    12.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017658-11 Sponsor Protocol Number: FER-ASAP-2009-01 Start Date*: 2010-05-03
    Sponsor Name:Vifor Pharma
    Full Title: An open-label, multicentre, randomised, 2-arm study to investigate the comparative efficacy and safety of intravenous ferric carboxymaltose versus oral iron for the treatment of iron deficiency ana...
    Medical condition: Iron deficiency anaemia in pregnant woman
    Disease: Version SOC Term Classification Code Term Level
    17.1 10005329 - Blood and lymphatic system disorders 10022972 Iron deficiency anaemia PT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017675-16 Sponsor Protocol Number: OFT113725 Start Date*: 2010-11-30
    Sponsor Name:Plymouth Hospitals NHS Trust
    Full Title: Phase II Trial of Single Agent Ofatumumab in Relapsed / Refractory Mantle Cell Lymphoma
    Medical condition: Relapsed or refractory Mantle Cell Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026800 Mantle cell lymphoma recurrent PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10026801 Mantle cell lymphoma refractory PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015681-55 Sponsor Protocol Number: C-09-023 Start Date*: 2010-03-18
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Dose-Escalation Study of AL-39324 Suspension versus Lucentis™ for the Treatment of Exudative Age-Related Macular Degeneration
    Medical condition: Exudative Age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    14.0 10015919 - Eye disorders 10025409 Macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001287-75 Sponsor Protocol Number: CPP-340 Start Date*: 2007-06-11
    Sponsor Name:CENTRE PAUL PAPIN - IRCAM
    Full Title: Proteomic and genetic analysis of neurotoxicity predicting markers in oxaliplatine treated patients with colorectal carcinoma.
    Medical condition: Colorectal cancer patients undergoing treatment with oxaliplatine every 15 days, 5 fluoro uracile and calcium levofolinate, for adjuvant or metastatic setting will be recruited in this study. T...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010029 Colorectal cancer NOS LLT
    9.1 10010034 Colorectal cancer stage III LLT
    9.1 10010027 Colorectal cancer Duke's C LLT
    9.1 10010035 Colorectal cancer stage IV LLT
    9.1 10052358 Colorectal cancer metastatic LLT
    9.1 10052360 Colorectal adenocarcinoma LLT
    9.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001292-11 Sponsor Protocol Number: NMSG 17/07 Start Date*: 2007-08-05
    Sponsor Name:Nordic Myeloma Study Group
    Full Title: Talidomid vs Velcade vid melfalanrefraktärt myelom
    Medical condition: Multiple myeloma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001633-34 Sponsor Protocol Number: FLT3503 Start Date*: 2008-06-17
    Sponsor Name:Mundipharma Research Ltd
    Full Title: A double blind, double dummy, randomised, multicentre, four arm parallel group study to assess the efficacy and safety of FlutiForm™ pMDI 250/10 µg (2 puffs bid) vs Fluticasone pMDI 250 µg (2 puffs...
    Medical condition: Asthma bronchial
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003555 Asthma bronchial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) BG (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-013259-31 Sponsor Protocol Number: 6232 Start Date*: 2009-12-29
    Sponsor Name:UMC Utrecht
    Full Title: A multicenter double blind placebo-controlled randomised trial for benign esophageal anastomotic strictures: Savary dilation vs savary dilation with Triamcinolon
    Medical condition: Patients with first time dysphagia (grade 2-4) due to a benign anastomotic esophageal stricture
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015449 Esophageal stricture LLT
    9.1 10030199 Oesophageal stricture LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001661-41 Sponsor Protocol Number: Ser01 Start Date*: 2006-06-08
    Sponsor Name:Karolinska University Hospital
    Full Title: Body Composition and Metabolic Changes During Antipsychotic Treatment. A Randomized Trial Comparing Sertindole and Olanzapine.
    Medical condition: Patients with schizophrenia diagnosis (DSM-IV)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-009372-13 Sponsor Protocol Number: 2009-01b Start Date*: 2009-11-03
    Sponsor Name:Institut de Cancérologie de la Loire
    Full Title: A phase II, multi-center, open-label, repeat-dose study of Lenalidomide (Revlimid ®) plus low-dose Dexamethasone in patients with refractory B-cell lineage acute lymphoblastic leukemia or in relaps...
    Medical condition: Treatment for B-cell Acute lymphoblastic leukemia in relapse.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-009421-29 Sponsor Protocol Number: AAA1 Start Date*: 2009-05-14
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: Non - invasive assessment of inflammatory burden in small abdominal aortic aneurysms: A USPIO - enhanced Magnetic Resonance Imaging (MRI) study
    Medical condition: The thrust of this pilot study is to investigate the utility of USPIO - enhanced MR to image abdominal aortic aneurysms with the aim of highlighting focal areas of inflammation and macrophage infil...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059696 Scan with contrast LLT
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-009428-36 Sponsor Protocol Number: CHUBX2008/34 Start Date*: 2009-03-17
    Sponsor Name:CHU de Bordeaux
    Full Title: Imagerie moléculaire in vivo des transmissions cholinergique et dopaminergique dans les démences à corps de Lewy par tomographie d’émission monophotonique : Applications au diagnostic et à l’identi...
    Medical condition: Démences à corps de Lewy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057095 Diffuse Lewy body disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005096-93 Sponsor Protocol Number: 070864 Start Date*: 2009-09-03
    Sponsor Name:Jordi Carratalá
    Full Title: SIMVASTATINA EN LA NEUMONIA ADQUIRIDA EN LA COMUNIDAD QUE REQUIERE HOSPITALIZACION. ESTUDIO ALEATORIZADO, DOBLE-CIEGO, CONTROLADO CON PLACEBO (SIMVASTATIN IN COMMUNITY-ACQUIRED PNEUMONIA REQUIRIN...
    Medical condition: NEUMONIA ADQUIRIDA EN LA COMUNIDAD QUE REQUIERE HOSPITALIZACION (COMMUNITY-ACQUIRED PNEUMONIA REQUIRING HOSPITALIZATION)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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