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Clinical trials for Transplant

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,544 result(s) found for: Transplant. Displaying page 22 of 78.
    EudraCT Number: 2013-000534-35 Sponsor Protocol Number: CSM/CIT Start Date*: 2013-07-12
    Sponsor Name:Fundación Castellano Leonesa de Hematología y Hemoterapia (FUCALHH)
    Full Title: Phase II clinical trial in the treatment of cytopenias allogeneic post-transplant with a sequential infusion of allogeneic mesenchymal cells expanded in vitro.
    Medical condition: Allogeneic post-transplant cytopenias.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000130-37 Sponsor Protocol Number: MM-SDX-105-01 Start Date*: 2014-09-12
    Sponsor Name:FONDAZIONE NEOPLASIE SANGUE ONLUS (FO.NE.SA. Onlus)
    Full Title: Prospective, phase II study to evaluate the efficacy and the safety of a combination of bendamustine-melphalan as preparative regimen to autologous transplantation of hematopoietic cells for multi...
    Medical condition: Multiple myeloma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000673-24 Sponsor Protocol Number: PHRC_N_2018_BAY Start Date*: 2021-04-15
    Sponsor Name:CHU de Clermont-Ferrand
    Full Title: Faecal microbiota transplantation for prevention of graft-versus-host sisease after allogeneic stem cell transplantation for haematological malignancies
    Medical condition: Patient who underwent Allogeneic hematopoietic stem cell transplantation (allo-HSCT) for various haematological malignancies. Faecal microbiota transplantation (FMT) will be assessed to prevent al...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-005425-13 Sponsor Protocol Number: 2014.848 Start Date*: 2015-02-13
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Evaluation of a stategy based on the 3-month screening biopsy to optimize the immunosuppression in renal transplantation
    Medical condition: Renal transplantation
    Disease: Version SOC Term Classification Code Term Level
    19.1 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005575-13 Sponsor Protocol Number: CMV12/12 Start Date*: 2013-05-16
    Sponsor Name:Antwerp University Hospital
    Full Title: Prophylactic vaccination with autologous dendritic cells against human cytomegalovirus: a pilot study in patients awaiting kidney transplantation
    Medical condition: Cytomegalovirus infection in patients awaiting kidney transplantation and after kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004865 10046859 Vaccination LLT
    15.1 100000004857 10023418 Kidney failure LLT
    15.1 100000004862 10009703 CMV infection LLT
    15.1 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000992-26 Sponsor Protocol Number: VAPOR002 Start Date*: 2016-06-29
    Sponsor Name:University Medical Center Groningen
    Full Title: Volatile Anesthetic Protection Of Renal transplants 2
    Medical condition: kidney transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) DK (Completed) ES (Completed) NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003184-29 Sponsor Protocol Number: PHAO2011-YL/ADEQUATE Start Date*: 2013-04-30
    Sponsor Name:CHRU de Tours
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001205-99 Sponsor Protocol Number: FG-506-02-IT-01 Start Date*: 2004-07-19
    Sponsor Name:FUJISAWA
    Full Title: AN OPEN, MULTICENTRE, RANDOMISED, PARALLEL GROUP STUDY TO COMPARE IN MARGINAL OLD-FOR-OLD RENAL TRANSPLANT PATIENTS THE SAFETY AND EFFICACY OF TWO TREATMENTS: SEQUENTIAL MYCOPHENOLATE MOFETIL / DE...
    Medical condition: prevention of rejection of marginal old-for-old renal transplant
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001131-30 Sponsor Protocol Number: EZ-2053-001 Start Date*: 2005-07-22
    Sponsor Name:Fresenius Biotech North America
    Full Title: A Double-Blind, Placebo-Controlled, Multicenter, Dose-ranging Study of an Anti-T-lymphocyte Immunglobuline (EZ-2053) in the Prophylaxis of Acute Pulmonary Allograft Rejection in Adult Recipients of...
    Medical condition: Patients with end-stage pulmonary failure, who are receiving a primary single or double pulmonary allograft
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003494-25 Sponsor Protocol Number: CAEB071A2203 Start Date*: 2006-08-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: 12-month open label, randomized, multicenter study evaluating efficacy, safety and tolerability of oral AEB071 plus tacrolimus (converted to myfortic after 3 months), vs. myfortic plus tacrolimus i...
    Medical condition: First evaluation of the efficacy and safety of AEB071 in its target indication: prevention of rejection in solid organ tranplantation. The study population will consist of a representative group of...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) ES (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-003672-19 Sponsor Protocol Number: EVERINA Start Date*: 2006-10-24
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: NON APPLICABILE
    Medical condition: Immunosoppressive therapy in liver transplanted patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050434 Prophylaxis against liver transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003817-28 Sponsor Protocol Number: 2014-003817-28 Start Date*: 2015-09-21
    Sponsor Name:Region Östergötland
    Full Title: Does bisfosfonat preserve the bone volume in transplanted bone in the jaw?
    Medical condition: Jaw abnormality
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011818-21 Sponsor Protocol Number: UCL/09/0128 Start Date*: 2010-06-28
    Sponsor Name:University College London [...]
    1. University College London
    2.
    Full Title: Transplantation of umbilical cord blood from unrelated donors in patients with haematological diseases using a myeloablative conditioning regimen
    Medical condition: Haematological disorders
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004851 10018847 Haematological disorders HLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000999-15 Sponsor Protocol Number: ONEmreg12 Start Date*: 2014-02-10
    Sponsor Name:University Hospital Regensburg
    Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation - M reg Trial
    Medical condition: Kidney allograft rejection following living-donor renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004863 10051366 Kidney graft dysfunction LLT
    17.0 100000004870 10049581 Graft rejection episode LLT
    17.0 100000004863 10069030 Graft failure LLT
    17.0 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    17.0 100000004870 10038297 Rejection acute renal LLT
    17.0 100000004870 10021510 Immunosuppression NOS LLT
    17.0 100000004863 10038299 Rejection chronic renal LLT
    17.0 100000004870 10066543 Acute allograft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001604-30 Sponsor Protocol Number: 1001 Start Date*: 2017-12-11
    Sponsor Name:Medical University of Vienna
    Full Title: Safety, Tolerability and Efficacy of anti-IL-6 Antibody Clazakizumab in Late Antibody-Mediated Rejection after Kidney Transplantation - A Pilot Trial
    Medical condition: Antibody-mediated rejection of a kidney transplant
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002519-17 Sponsor Protocol Number: DDD16JRtac Start Date*: 2016-09-12
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: Supersaturation and precipitation of tacrolimus in the stomach of healthy volunteers
    Medical condition: Healthy human volunteers , investigation of the drug's supersaturation behaviour in the stomach
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-004308-36 Sponsor Protocol Number: OuTSMART Start Date*: 2013-01-14
    Sponsor Name:Kings College London [...]
    1. Kings College London
    2. Guy's and St Thomas' Foundation NHS Trust
    Full Title: A randomized controlled clinical trial to determine if a combined screening /treatment programme can prevent premature failure of renal transplants due to chronic rejection in patients with HLA an...
    Medical condition: Renal Transplant recipients with HLA antibodies, who are at increased risk of graft dysfunction and graft failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2018-001489-41 Sponsor Protocol Number: P00003466 Start Date*: 2018-07-02
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Radiation- and alkylator-free hematopoietic cell transplantation for bone marrow failure due to dyskeratosis congenita / telomere disease
    Medical condition: Dyskeratosis congenita / telomere disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10001756 Allogenic bone marrow transplantation therapy PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000789-19 Sponsor Protocol Number: MiniCept Start Date*: 2007-05-30
    Sponsor Name:CHU de Liège, Domaine Universitaire du Sart Tilman
    Full Title: Withdrawal of Calcineurin Inhibitors (CNIs) during administration of Mycophenolate Mofetil (MMF) in liver transplant patients suffering adverse effects from CNIs: Study of the reduction in rejectio...
    Medical condition: liver transplant patients suffering adverse effects from treatment with calcineurin inhibitors
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050434 Prophylaxis against liver transplant rejection LLT
    9.1 10054980 Immunosuppressant drug therapy LLT
    9.1 10052538 Adverse drug reaction NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-000222-22 Sponsor Protocol Number: 2004/045 Start Date*: 2005-04-25
    Sponsor Name:OLV-ziekenhuis
    Full Title: Prospective Open Single-Centre Study on the Effect of Initiation of RAD and CNI minimalisation on renal function in heart transplant patients
    Medical condition: heart transplant patients with impaired renal function under treatment of CNI
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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