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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,351 result(s) found. Displaying page 26 of 2,218.
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    EudraCT Number: 2005-005749-20 Sponsor Protocol Number: 64210/H Start Date*: 2006-05-03
    Sponsor Name:Richter Gedeon Vegyészeti Gyár Rt
    Full Title: Amlodipint és lisinoprilt tartalmazó fix gyógyszerkombináció (Lisonorm®) hatásosságának és biztonságosságának vizsgálata essentialis hypertoniás betegeken (ALFESS)
    Medical condition: essentialis hypertónia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-004187-32 Sponsor Protocol Number: AVT-01/2/AST/02 Start Date*: 2007-01-23
    Sponsor Name:Avontec GmbH
    Full Title: Efficacy and safety of AVT-01 5 mg once daily over 7 days in patients with moderate persistent atopic asthma – A double-blind, randomized, placebo-controlled clinical study
    Medical condition: Male outpatients aged 18 - 65 with moderate persistent atopic asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004218-42 Sponsor Protocol Number: P060207 Start Date*: 2008-01-30
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Essai thérapeutique de phase IIA évaluant l'efficacité du Bortezomib (velcade) chez les patients atteints de la maladie de Waldenstrom en phase avancée
    Medical condition: Maladie de Waldenstrom réfractaire ou en rechute après une ou deux lignes de traitement ayant comporté des alkylants et/ou des analogues de purine et/ou un anticorps monoclonal seul ou en association.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10054695 Macroglobulinémie de Waldenström PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003834-40 Sponsor Protocol Number: 07NR07 Start Date*: 2008-10-31
    Sponsor Name:UCL-INSTITUTE OF CHILD HEALTH
    Full Title: THE IMPACT OF REDUCING OVERTREATMENT ON QUALITY OF LIFE IN CHILDREN WITH REFRACTORY EPILEPSY
    Medical condition: We are studying a population of children with refractory epilepsy.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10053551 Intractable epilepsy LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004513-33 Sponsor Protocol Number: OCTUMI-02 Start Date*: 2008-05-08
    Sponsor Name:University of Oxford
    Full Title: Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression
    Medical condition: Bipolar depression
    Disease: Version SOC Term Classification Code Term Level
    13.1 10037175 - Psychiatric disorders 10004936 Bipolar depression LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-004518-15 Sponsor Protocol Number: 28113 Start Date*: 2008-08-05
    Sponsor Name:Merck Serono International
    Full Title: A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Atacicept in Subjects with Lupus Nephritis in Combination with Mycophenolate Mofetil Therapy
    Medical condition: Lupus nephritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025140 Lupus nephritis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002469-11 Sponsor Protocol Number: CSPP100A2403 Start Date*: 2008-05-13
    Sponsor Name:Novartis Farmaceutica S.A.
    Full Title: Estudio aleatorizado, doble ciego, de grupos paralelos, multicéntrico, para comparar la eficacia y seguridad de aliskiren 300 mg administrado una vez al día y de aliskiren 150 mg administrado dos v...
    Medical condition: Hipertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002470-59 Sponsor Protocol Number: TRx-014-009 Start Date*: 2007-09-03
    Sponsor Name:TauRx Therapeutics Ltd
    Full Title: AN OPEN LABEL CONTINUATION STUDY OF THE EFFECTS OF MTC 30 MG TID AND 60 MG TID IN PATIENTS WITH ALZHEIMER’S DISEASE
    Medical condition: An estimated 685,000 people in the UK suffer from dementia, with Alzheimer’s disease (AD) being the most common cause affecting over 400,000 people (Alzheimers Society 2007). It is a devastating i...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10012271 Dementia Alzheimer's type PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002474-60 Sponsor Protocol Number: NN1250-1835 Start Date*: 2007-11-08
    Sponsor Name:Novo Nordisk A/S
    Full Title: A 16 week randomised, open labelled, 3-armed, treat-to-target, parallel group trial comparing SIBA (D) once daily + NovoRapid®, SIBA (E) once daily + NovoRapid® and insulin glargine once daily + No...
    Medical condition: type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005221-29 Sponsor Protocol Number: Sevoflurane vs. Desflurane Start Date*: 2007-02-21
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Curve di Wash-in/wash-out e tempi di recupero dopo anestesia con Sevoflurane vs. Desflurane in pazienti affetti da obesita' patologica
    Medical condition: Pazienti affetti da obesita' patologica e candidati ad intervento di by-pass bilio-intestinale.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027433 Metabolism and nutrition disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005232-81 Sponsor Protocol Number: Wet-wrap study Start Date*: 2008-09-11
    Sponsor Name:Havenziekenhuis/ErasmusMC
    Full Title: Wet-wrap treatment in children with atopic eczema using the wet-wrap method with diluted corticosteroids versus emollients
    Medical condition: atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003639 Atopic dermatitis LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002728-13 Sponsor Protocol Number: D/P3/07/4 Start Date*: 2008-03-17
    Sponsor Name:Diamyd Therapeutics AB
    Full Title: A Phase III, 3-Arm, Randomized, Double-Blind, Placebo-controlled, Multicenter Study to Investigate the Impact of Diamyd® on the Progression of Diabetes in Patients Newly Diagnosed with Type 1 Diabe...
    Medical condition: Patients for the proposed trial are those with recent onset type 1 diabetes (diagnosed within 3 months at screening).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) NL (Ongoing) FI (Prematurely Ended) DE (Prematurely Ended) ES (Prematurely Ended) SI (Prematurely Ended) GB (Prematurely Ended) FR (Ongoing) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002763-27 Sponsor Protocol Number: PRINS study Start Date*: 2007-09-12
    Sponsor Name:Erasmus MC
    Full Title: A multi-center, randomized, controlled trial with programmed introduction of Sirolimus-based, Calcineurin inhibitor free immunosuppression in recipients of non-heart-beating donor kidney grafts.
    Medical condition: Recipients of a renal allograft from a non-heart-beating donor, three months after transplantation.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002774-64 Sponsor Protocol Number: HP 3.1 Start Date*: 2007-12-04
    Sponsor Name:Deutsches Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler
    Full Title: Therapy of PAH – Treatment with Sildenafil in Eisenmenger Patients
    Medical condition: Patients with pre-existing congenital heart disease may develop Eisenmenger physiology (EP), characterized by development of pulmonary arterial hypertension and intracardiac right to left shunt. Th...
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002776-33 Sponsor Protocol Number: 80-82310-98-08626 Start Date*: 2007-10-29
    Sponsor Name:Academic hospital Maastricht
    Full Title: Treatment of superficial basal cell carcinoma by three non-invasive modalities: PDT vs. imiquimod vs. 5-fluorouracil
    Medical condition: superficial basal cell carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000446-12 Sponsor Protocol Number: CRO826 Start Date*: 2007-12-14
    Sponsor Name:Imperial College London
    Full Title: Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy
    Medical condition: Pulmonary hypertension associated with sickle cell disease
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006730-18 Sponsor Protocol Number: P060603 Start Date*: 2007-03-22
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: AMBIZYGO. Etude de phase II de l'efficacité d'une posologie initiale élevée d'amphotéricine B liposomale (AmBisome) (10mg/kg/j) dans le traitement des zygomycoses
    Medical condition: Patients atteints de zygomycose
    Disease: Version SOC Term Classification Code Term Level
    8.1 10061418 Infection fongique zygomycose PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002080-88 Sponsor Protocol Number: NA Start Date*: 2005-09-13
    Sponsor Name:Aintree Hospitals NHS Trust and University of Liverpool
    Full Title: A double−blind, placebo−controlled crossover trial to quantify the effects of sibutramine on energy intake and energy expenditure in obese subjects during a test meal
    Medical condition: Obesity defined as BMI > 30 kg /m2
    Disease: Version SOC Term Classification Code Term Level
    10029883
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002871-15 Sponsor Protocol Number: V58P13 Start Date*: 2007-09-14
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l.
    Full Title: A Phase III, Randomized, Observer-Blind, Placebo-Controlled, Multicenter Study to Assess Clinical Efficacy of a Cell-Derived Subunit Influenza Vaccine and an Egg-Derived Subunit Influenza Vaccine i...
    Medical condition: Influenza disease.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-002872-32 Sponsor Protocol Number: V58P14 Start Date*: 2007-11-01
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l.
    Full Title: A Phase IV, Multi-Center, Active-Controlled, Observer-Blind Study to Evaluate the Safety of a Trivalent Subunit Influenza Vaccine Produced either in Mammalian Cell Culture (Optaflu®) or in Embryona...
    Medical condition: no medical condition: healthy subjects
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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