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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 3 of 19.
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    EudraCT Number: 2014-004565-24 Sponsor Protocol Number: CNS7056-011 Start Date*: 2015-06-22
    Sponsor Name:PAION UK Limited
    Full Title: A Randomized, Single-blind, Propofol-controlled Phase III Study Evaluating the Efficacy and Safety of Remimazolam in General Anesthesia in Adult Patients Undergoing Cardiac Surgery, Including Follo...
    Medical condition: Anesthesia in adult patients undergoing cardiac surgery.
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10021722 Induction and maintenance anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-000961-19 Sponsor Protocol Number: 2019/376 Start Date*: 2019-08-26
    Sponsor Name:Helse Fonna
    Full Title: “Haemodynamic stability during induction of general anesthesia with propofol and remifentanil: A randomized, controlled, double-blind study comparing medium and low remifentanil doses.”
    Medical condition: In daily clinical work we observe a hypotensive effect and a reduction in heart rate when induction of general anesthesia is performed using propofol and remifentanil. It is difficult to differenti...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000958-56 Sponsor Protocol Number: 2019/375 Start Date*: 2019-08-16
    Sponsor Name:Helse Fonna
    Full Title: “Haemodynamic stability during induction of general anesthesia with propofol and remifentanil: A randomized, controlled, double-blind study comparing low vs high propofol doses.”
    Medical condition: In daily clinical work we observe a hypotensive effect and a reduction in HR when induction of general anesthesia is performed using propofol and remifentanil. It is difficult to differentiate the ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004632-40 Sponsor Protocol Number: AGO 2005/ANE/propsev Start Date*: 2005-11-25
    Sponsor Name:University Hospital Ghent
    Full Title: Study on the pharmacodynamic interactions between propofol and sevoflurane during induction of anesthesia.
    Medical condition: Anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001567-37 Sponsor Protocol Number: KUKIDEX-2 Start Date*: 2016-11-24
    Sponsor Name:University Medical Center Groningen
    Full Title: Efficacy of single dose intranasal dexmedetomidine for conscious sedation in dental practice in dentophobic uncooperative patients with intellectual disability.
    Medical condition: dentophobia intellectual disability
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001797-27 Sponsor Protocol Number: 2005/142 Start Date*: 2005-08-01
    Sponsor Name:University Hospital Ghent
    Full Title: Accuracy of the Kataria model for propofol anesthesia in children
    Medical condition: Dental and eye treatment under general anesthesia
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004538-40 Sponsor Protocol Number: MAGLIDIT-12 Start Date*: 2013-01-28
    Sponsor Name:Hospital General de Ciudad Real
    Full Title: Magnesium associated to intratecal lidocaine decreases the incidence of the Transitory Neurologic Syndrome following same-day-surgery
    Medical condition: Postanesthetic transitory neurologic syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004504-29 Sponsor Protocol Number: 49024 Start Date*: 2015-02-25
    Sponsor Name:Helse Fonna, Haugesund Sykehus
    Full Title: "Haemodynamic stability of bupivacaine with and without adrenaline for paracervical block during general anesthesia. A randomized controlled double blinded study."
    Medical condition: Cervical conisation is done for pre-cancer disease. The procedure is done with local anesthesia and general anesthesia. Local anesthesia is given by paracervical block, and several different local ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003151-36 Sponsor Protocol Number: AGO/2007/006 Start Date*: 2007-08-01
    Sponsor Name:University Hospital Ghent
    Full Title: Sevoflurane-Remifentanil interaction: Multiple response surfaces, validation of calibration stimuli, validation of the intraoperative isobole concept and investigating remifentanil induced opioid t...
    Medical condition: American Society of Anesthesia class I and II patients scheduled for surgery under general anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002769-37 Sponsor Protocol Number: cervikalblock Start Date*: 2012-10-23
    Sponsor Name:UK für Anästhesiologie und allgemeine Intensivmedizin, LKH Salzburg
    Full Title: Influence of the concentration of the local anesthetic ropivacaine in the quality of a ultrasound guided block of the regio collis lateralis for carotid endarterectomy: a prospective, randomized an...
    Medical condition: Regional anesthesia for carotid endarterectomy surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001139-98 Sponsor Protocol Number: IC2021-07 Start Date*: 2022-06-13
    Sponsor Name:Institut Curie
    Full Title: Opioid-Free versus Opioid-Based Anaesthesia for secondary free-flap reconstruction surgery of the breast: A phase III multicentric randomized controlled study
    Medical condition: Anaesthesia during secondary free flap reconstruction surgery of the breast.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10002323 Anesthesia general LLT
    20.0 10042613 - Surgical and medical procedures 10006305 Breast reconstruction PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005886-15 Sponsor Protocol Number: VASOCONTROL-I Start Date*: 2021-07-21
    Sponsor Name:University Medical Center Groningen
    Full Title: Evaluation of pharmacokinetic and –dynamic characteristics of norepinephrine for the augmentation of arterial blood pressure in healthy volunteers prior to and during general anesthesia
    Medical condition: Bloodpressure during anaesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015867-15 Sponsor Protocol Number: DBS Start Date*: 2010-02-18
    Sponsor Name:AZIENDA OSPEDALIERA SAN GERARDO DI MONZA
    Full Title: Different Anesthesiological Strategies Evaluation in Deep Brain Stimulation Neurosurgeries
    Medical condition: Parkinson Desease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002528-10 Sponsor Protocol Number: SIVAA01 Start Date*: 2017-07-06
    Sponsor Name:Vestfold Hospital Trust
    Full Title: TOF trial: A randomized double blinded controlled Trial comparing low dose Of sugammadex and neostigmine aFter use of rocuronium during general anesthesia in patients undergoing non-cardiac surgery
    Medical condition: The study population will include all patients >18 years scheduled for an elective surgical procedure undergoing general anesthesia with intravenous drugs and non-depolarizing NMBA (rocuronium), wi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-000174-29 Sponsor Protocol Number: CNS7056-022 Start Date*: 2018-07-25
    Sponsor Name:PAION UK Limited
    Full Title: Phase III confirmatory efficacy and safety trial of remimazolam (CNS7056) compared with propofol for intravenous anaesthesia during elective surgery
    Medical condition: Induction and maintenance of general anaesthesia (GA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10018061 General anesthesia LLT
    20.0 100000004865 10054434 Induction and maintenance of anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed) GB (Prematurely Ended) NL (Prematurely Ended) FR (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001300-30 Sponsor Protocol Number: 2017_CERVPLEX_1.1 Start Date*: 2017-10-03
    Sponsor Name:UK für Anästhesieologie, Gemeinn. Sbg. Landeskliniken BetriebsgesmbH
    Full Title: Comparison of deep, intermediate and superficial cervical plexus block for carotid endarterectomies concerning paresis of the phrenic nerve, lung function and tissue distribution: a prospective, ra...
    Medical condition: deep, intermediate or superficial cervical plexus block for carotid endarterectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002325-11 Sponsor Protocol Number: AT052016 Start Date*: 2016-07-27
    Sponsor Name:Univerity Hospital Leuven
    Full Title: Intravenous regional anesthesia versus axillar block for hand surgery in day-care hospitall: A prospective, randomised, comparative trial
    Medical condition: intra and post operative pain management
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-002824-19 Sponsor Protocol Number: NA Start Date*: 2021-08-12
    Sponsor Name:CHU de Liège
    Full Title: Study of the hypnotic and anti-nociceptive components of Magnesium using Electroencephalogram Spectral Entropy and pupillometry during total intravenous general anesthesia : a randomized double-bli...
    Medical condition: Total thyroidectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003903-32 Sponsor Protocol Number: spinankle01 Start Date*: 2020-08-26
    Sponsor Name:University of Oulu
    Full Title: Spinal anesthesia and general anesthesia in ankle fracture patients - a prospective, randomized controlled trial
    Medical condition: Ankle fracture needing surgical fixation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001908-38 Sponsor Protocol Number: 08042012 Start Date*: 2012-07-12
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: The effect of intravenous ketamine on the MAC of sevoflurane – a randomized, placebo controlled, double blinded clinical trial
    Medical condition: We want to test if intravenous s-ketamine of two different doses has an effect on MAC of sevoflurane
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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