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Clinical trials for Melatonin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    82 result(s) found for: Melatonin. Displaying page 3 of 5.
    « Previous 1  2  3  4  5  Next»
    EudraCT Number: 2011-004138-33 Sponsor Protocol Number: EnuMel-11 Start Date*: 2011-12-23
    Sponsor Name:Søren Rittig
    Full Title: The effect of melatonin on nocturnal enuresis
    Medical condition: nocturnal enuresis
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004857 10029453 Nocturnal enuresis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005719-89 Sponsor Protocol Number: 12440 / R-0631M / Melody Start Date*: 2007-01-04
    Sponsor Name:Meander Medical Center
    Full Title: Double blind placebo controlled study on the efficacy of melatonin on sleep parameters and quality of life in hemodialysis patients
    Medical condition: Sleep problems in hemodialysis patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10040991 Sleep disorders and disturbances HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-002934-34 Sponsor Protocol Number: 2020-AKA Start Date*: 2020-11-04
    Sponsor Name:Aarhus University Hospital, dept. of Diabetes and Hormonal diseases
    Full Title: The effects of melatonin treatment on bone, marrow, sleep and arterial stiffness in postmenopausal women
    Medical condition: Osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031285 Osteoporosis postmenopausal PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-017825-21 Sponsor Protocol Number: EC09/081 Start Date*: 2012-11-19
    Sponsor Name:INSTITUTO ARAGONÉS DE CIENCIAS DE LA SALUD
    Full Title: Prospective, randomised, double-blind study to evaluate the efficacy of treatment with melatonin in adult patients with severe sepsis or septic shock.
    Medical condition: Severe sepsis or septic shock.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003313-42 Sponsor Protocol Number: AGO-TEA Start Date*: 2012-03-29
    Sponsor Name:Hospital General Universitario de Alicante
    Full Title: Efficacy of agomelatine on sleep disturbance in Autism Spectrum Disorder (ASD)
    Medical condition: The treatment of sleep disorders in patients with autism spectrum disorders (ASD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000281-23 Sponsor Protocol Number: Oxford University(None) Start Date*: 2009-09-10
    Sponsor Name:University of Oxford
    Full Title: Melatonin in Acute Mania Investigation (MIAMI-UK)
    Medical condition: Bipolar Disorder (mania and hypomania)
    Disease: Version SOC Term Classification Code Term Level
    12 10000852 Acute Mania LLT
    12 10021030 Hypomania LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004025-28 Sponsor Protocol Number: HTA 05-14-02 Start Date*: 2007-06-26
    Sponsor Name:Royal Liverpool Children’s NHS Trust
    Full Title: MENDS: The use of MElatonin in children with Neuro-developmental Disorders and impaired Sleep; a randomised, double-blind, placebo-controlled, parallel study
    Medical condition: children with neuro-developmental disorders and impaired sleep
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064062 Neurodevelopmental disorder PT
    9.1 10040984 Sleep disorder PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006795-30 Sponsor Protocol Number: Satauni Start Date*: 2009-01-16
    Sponsor Name:Institute of Clinical Medicine, Family Medicine, University of Turku
    Full Title: Controlled-release melatonin in fast withdrawal of temazepam, zopiclone or zolpidem in elderly persons with insomnia
    Medical condition: Individuals over 55 years with primary insomnia and DDD need of temazepam, zopiclone or zolpidem
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036701 Primary insomnia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004670-28 Sponsor Protocol Number: 2011-AKA Start Date*: 2012-04-25
    Sponsor Name:Aarhus University Hospital, Dept of Endocrinology and Internel Medicine (MEA)
    Full Title: Treatment of osteopenia with melatonin: Effects on BMD, muscle strength and quality of life
    Medical condition: Osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031282 Osteoporosis PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-001530-35 Sponsor Protocol Number: MeCOVID Start Date*: 2020-04-09
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital La Paz (FIBHULP)
    Full Title: Randomized multicenter clinical trial to evaluate the efficacy of melatonin in the prophylaxis of SARS-CoV-2 infection in high-risk contacts. COVID-19
    Medical condition: SARS-CoV-2 infection in high-risk contacts
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022460-12 Sponsor Protocol Number: MVH-03 Start Date*: 2011-03-23
    Sponsor Name:Herlev Hospital
    Full Title: The effect of melatonin on depression, anxiety, cogntive function and sleep disturbances in breast cancer patients
    Medical condition: Depression Anxiety Postoperative cognitive dysfunction Sleep disturbances
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012378 Depression LLT
    12.1 10002855 Anxiety LLT
    12.1 10009845 Cognitive disturbance LLT
    12.1 10040997 Sleep disturbances LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-008377-56 Sponsor Protocol Number: 2008-249 Start Date*: 2009-03-10
    Sponsor Name:Palliativ medicinsk afdeling, Bispebjerg Hospital
    Full Title: Melatonin for træthed og andre symptomer hos patienter med fremskreden kræft
    Medical condition: Træthed og andre symptomer hos patienter med freskreden kræft i palliativ fase
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033372 Pain and discomfort NEC HLT
    9.1 10016258 Fatigue management LLT
    9.1 10022437 Insomnia LLT
    9.1 10003028 Appetite lost LLT
    9.1 10012378 Depression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002697-37 Sponsor Protocol Number: 14/0382 Start Date*: 2015-04-15
    Sponsor Name:University College London
    Full Title: Single-centre open label exploratory phase IIb pilot study of exogenous oral Melatonin for the treatment of Nocturia in adults with Parkinson’s disease
    Medical condition: Parkinson's Disease Nocturia
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    17.1 10029205 - Nervous system disorders 10034007 Parkinson's disease NOS LLT
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-005017-12 Sponsor Protocol Number: EyeADHD-01 Start Date*: 2014-03-31
    Sponsor Name:Parnassia Bavo Groep - PsyQ
    Full Title: Looking into the eye of ADHD. Investigating the relationship between ADHD, the delayed circadian rhythm and the functioning of the eye.
    Medical condition: Adults with ADHD and suboptimal eye functioning.
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004873 10064104 ADHD LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-000120-17 Sponsor Protocol Number: APL-510-009 Start Date*: 2005-03-24
    Sponsor Name:Alliance Pharmaceuticals Ltd
    Full Title: A double-blind placebo-controlled cross-over study to determine if melatonin can improve the length of day time sleep in subjects with transient misalignment of the sleep-wake cycle as a result of ...
    Medical condition: Transient misalignment of the sleep-wake cycle as a result of working night shifts (insomnia in night shift workers)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005886-15 Sponsor Protocol Number: VASOCONTROL-I Start Date*: 2021-07-21
    Sponsor Name:University Medical Center Groningen
    Full Title: Evaluation of pharmacokinetic and –dynamic characteristics of norepinephrine for the augmentation of arterial blood pressure in healthy volunteers prior to and during general anesthesia
    Medical condition: Bloodpressure during anaesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000320-18 Sponsor Protocol Number: FASE01 Start Date*: 2012-11-22
    Sponsor Name:Parnassia Bavo Groep - PsyQ
    Full Title: Phase shift in adult ADHD of sleep and apetite.
    Medical condition: Delayed Sleep Phase Syndrome (DSPS) in adult patients with Attention-Deficit/Hyperctivity Disorder (ADHD)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004873 10064104 ADHD LLT
    16.1 10029205 - Nervous system disorders 10012209 Delayed sleep phase PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2012-005254-30 Sponsor Protocol Number: EuRhythDiaII Start Date*: 2013-12-27
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Multicenter, randomized, double-blind, placebo controlled trial of 2 mg melatonin for circadian phase adjustment and improvement of metabolic control in night shift workers
    Medical condition: Insomnia because of disturbed sleep-work-rhythm
    Disease: Version SOC Term Classification Code Term Level
    17.0 10037175 - Psychiatric disorders 10032168 Other insomnia LLT
    17.0 10037175 - Psychiatric disorders 10022443 Insomnia related to another mental condition PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001230-17 Sponsor Protocol Number: 2012.732 Start Date*: 2013-08-14
    Sponsor Name:Hospices Civils de Lyon
    Full Title: La mélatonine restaure-t-elle l’architecture du sommeil chez les enfants avec autisme ? Etude de phase II.
    Medical condition: Autisme infantile Troubles du sommeil
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10021737 Infantile autism LLT
    18.0 10037175 - Psychiatric disorders 10040991 Sleep disorders and disturbances HLGT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000914-37 Sponsor Protocol Number: NEU 1X Start Date*: 2004-08-12
    Sponsor Name:Neurim Pharmaceuticals (1991) Ltd
    Full Title: A DOUBLE-BLIND, PARALLEL GROUP, RANDOMISED, PLACEBO CONTROLLED STUDY OF THE EFFICACY AND SAFETY OF CIRCADIN® 2MG IN THE IMPROVEMENT OF SLEEP QUALITY IN PATIENTS WITH INSOMNIA AGED 55-80 YEARS.
    Medical condition: Primary Insomnia in adults over 55 years
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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