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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 4 of 19.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2014-005116-41 Sponsor Protocol Number: AOP0071 Start Date*: 2015-06-24
    Sponsor Name:University of Padova
    Full Title: Postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy after administration of sugammadex and neostigmine. A double-blind, randomized controlled trial.
    Medical condition: Reversal of rocuronium-induced neuromuscular blockade
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001646-10 Sponsor Protocol Number: ANIMAL-523-2014-2569 Start Date*: 2017-06-22
    Sponsor Name:Uppsala University Hospital
    Full Title: Anesthesia Induced Hormonal Oliguria Trial
    Medical condition: Anaesthesia in adult patients undergoing general surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000678-20 Sponsor Protocol Number: SEVODESHV Start Date*: 2014-09-02
    Sponsor Name:UZ Brussel
    Full Title: Does isocapnic hyperventilation hasten early recovery with sevoflurane and desflurane in O2/air?
    Medical condition: The absence of hypocapnia on the moment of emergence from general inhalatory anesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002928-34 Sponsor Protocol Number: 021049 Start Date*: 2006-04-24
    Sponsor Name:NV Organon
    Full Title: A randomized, assessor-blind, dose-ranging, phase IIIB, multicenter trial comparing the intubating conditions and time course of block of three different intubating doses (0.45 mg/kg, 0.6 mg/kg, an...
    Medical condition: Not applicable
    Disease:
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-000254-13 Sponsor Protocol Number: RD/613/07 Start Date*: 2008-10-14
    Sponsor Name:Gwent Healthcare NHS Trust
    Full Title: A double blind randomised placebo controlled study assessing the effect of intra-operative local anaesthetic administration on postoperative pain in adolescent children undergoing oral surgery unde...
    Medical condition: Postoperative pain following oral surgery in 12 to 16 year olds
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024759 Local anaesthetic LLT
    9.1 10054711 Postoperative pain LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018166-36 Sponsor Protocol Number: XENON-2009 Start Date*: 2010-03-18
    Sponsor Name:CHU de Poitiers
    Full Title: Evaluation de l’entretien de l’anesthésie générale sous Xénon comparé au Desflurane au cours de l’endartérectomie carotidienne, étude prospective, randomisée et comparative.
    Medical condition: Carotid artery stenosis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10007687 Carotid artery stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004072-12 Sponsor Protocol Number: 19.4.312 Start Date*: 2007-02-01
    Sponsor Name:NV Organon
    Full Title: A multi-center, randomized, parallel-group, safety assessor-blinded trial comparing efficacy and safety of 4.0 mg.kg-1 Org 25969, administered at T1 3-10% after continuous infusion of rocuronium, a...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007162-38 Sponsor Protocol Number: 19.4.335 Start Date*: 2008-03-17
    Sponsor Name:NV Organon
    Full Title: A multi-center, open label trial, to show efficacy and safety of 4.0 mg.kg-1 sugammadex administered at a depth of neuromuscular blockade of 1-2 PTC induced by rocuronium in Chinese and European AS...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002883-20 Sponsor Protocol Number: WALIBI-001 Start Date*: 2013-09-30
    Sponsor Name:University Medical Center Groningen
    Full Title: Walking the Isobole of drug Interaction: Comparison of hemodynamic effects, cerebral and tissue oxygenation for 4 equipotent combinations of propofol and remifentanil
    Medical condition: elective ophthalmic surgery under general anesthesia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012449-48 Sponsor Protocol Number: ALS-8-09-A-101 Start Date*: 2009-11-09
    Sponsor Name:Air Liquide Santé International
    Full Title: „Sympathetic neural outflow during Xenon anesthesia in humans“
    Medical condition: We would like to frame the thesis, that a general, inhalative Xenon anesthesia (1 MAC) does not effect the sympathetic outflow and the sympathetic baroreflex reagibility under spontaneous breathing...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001660-30 Sponsor Protocol Number: CHL.3/01-2019/M Start Date*: 2020-06-03
    Sponsor Name:Sintetica S.A.
    Full Title: A prospective, observer-masked, randomized clinical trial to investigate and compare the clinical efficacy of chloroprocaine 3% gel and tetracaine 0.5% eye drop as topical anesthetics in phacoemuls...
    Medical condition: cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10063797 Cataract operation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-000188-33 Sponsor Protocol Number: MK-8616-146 Start Date*: 2017-10-27
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 4 Randomized, Active-Comparator Controlled Trial to Study the Efficacy and Safety of Sugammadex (MK-8616) for the Reversal of Neuromuscular Blockade Induced by Either Rocuronium Bromide or ...
    Medical condition: Reversal of neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10018061 General anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-000961-22 Sponsor Protocol Number: 16/009U Start Date*: 2016-11-14
    Sponsor Name:Ziekenhuis Oost-Limburg
    Full Title: Quality of analgesia after ultrasound-guided specific blocks of the distal tibial and deep peroneal nerves with 15 mL of a 50:50 mixture bupivacaine 0.5% and liposome bupivacaine (Exparel®) )1.3% ...
    Medical condition: Hallux valgus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003679-32 Sponsor Protocol Number: 984 Start Date*: 2021-11-25
    Sponsor Name:Sint Maartenskliniek
    Full Title: Erector spinae plane block for reduction of early postoperative pain scores and opioid use in lumbar spinal fusion surgery, a prospective double-blinded randomized placebo controlled trial
    Medical condition: Patients planned to undergo elective lumbar spinal fusion surgery with a dorsal surgical approach
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000692-92 Sponsor Protocol Number: MK-8616-089 Start Date*: 2019-02-01
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 4 Double-Blinded, Randomized, Active Comparator-Controlled Clinical Trial to Study the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade ...
    Medical condition: Reversal of neuromuscular blockade (NMB)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) FI (Completed) BE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-004942-12 Sponsor Protocol Number: Protokol_MFCN_10102020 Start Date*: 2020-11-19
    Sponsor Name:Aarhus University Hospital
    Full Title: Selective ultrasound-guided nerve block of the medial femoral cutaneous nerve in healthy volunteers
    Medical condition: Pain around the surgical incisions after total knee arthroplasty (TKA). The area anesthetized by new nerve block techniques anesthetizing the medial femoral cutaneous nerve are investigated in heal...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    21.0 100000004865 10002325 Anesthesia local LLT
    20.1 10022891 - Investigations 10045434 Ultrasound scan PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-021783-15 Sponsor Protocol Number: Version 1.0 Start Date*: 2010-12-31
    Sponsor Name:Guys and St Thomas' NHS Foundation Trust
    Full Title: Ropivacaine 0.75% versus Levobupivacaine 0.5% for conversion of labour epidural to surgical anaesthesia for emergency Caesarean section. (RoLe Trial)
    Medical condition: Conversion of labour epidural to surgical anaesthesia for emergency Caesarean section
    Disease: Version SOC Term Classification Code Term Level
    12.1 10006924 Caesarean section LLT
    12.1 10054375 Epidural anesthesia LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-002510-23 Sponsor Protocol Number: SR062014 Start Date*: 2014-09-17
    Sponsor Name:University hospitals of Leuven
    Full Title: as an adjuvant to sevoflurane anaesthesia in children undergoing interventional or diagnostic cardiac catheterization: a randomized controlled clinical trial
    Medical condition: Xenon anesthesia in children undergoing cardiac catheterization
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002356-16 Sponsor Protocol Number: SUS2012CMR01 Start Date*: 2012-11-27
    Sponsor Name:Stavanger University Hospital
    Full Title: Pre-emptive local anaesthesia in gynecological laparoscopy.
    Medical condition: Gynecological patients referred for elective day-care laparoscopic surgery.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10021946 Infiltration anesthesia LLT
    14.1 10022891 - Investigations 10023693 Laparoscopy PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000166-21 Sponsor Protocol Number: 1 Start Date*: 2007-06-22
    Sponsor Name:Whipps Cross University Hospital
    Full Title: A comparison of the efficacy of 10% lidocaine solution and EMLA cream as local anaesthetic for the insertion of tympanic membrane ventilation tubes.
    Medical condition: Grommet/ventilation tube insertion in adults with otitis media with effusion (glue ear).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024759 Local anaesthetic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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