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Clinical trials for Musculoskeletal diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,431 result(s) found for: Musculoskeletal diseases. Displaying page 4 of 72.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2011-005368-55 Sponsor Protocol Number: SM1-UG-11 Start Date*: 2012-01-26
    Sponsor Name:Professor Joergen Berg Dahl
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001678-26 Sponsor Protocol Number: LOCAL/2018/PC-02 Start Date*: 2019-09-11
    Sponsor Name:CHU de NIMES
    Full Title: Erectus nerve block for lumbar spine surgery : a prospective randomized study
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10061683 Arthrodesis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002542-37 Sponsor Protocol Number: P170409J Start Date*: 2018-11-13
    Sponsor Name:Assistance Publique Hôpitaux de Paris
    Full Title: NA
    Medical condition: acute gout crisis
    Disease:
    Population Age: Gender:
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005664-10 Sponsor Protocol Number: BMP2/1 Start Date*: 2015-09-30
    Sponsor Name:UZ Leuven Orthopedic research
    Full Title: InductOs® (rhBMP-2; dibotermin alfa) vs. autologous bone grafting for the treatment of nonunion of the docking site in tibial bone transport
    Medical condition: fractured non-healing tibia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-000300-42 Sponsor Protocol Number: 03AR0298 Start Date*: 2013-01-18
    Sponsor Name:National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
    Full Title: A long-term outcome study with the IL-1 receptor antagonist Anakinra/Kineret® in patients with Neonatal onset multisystem inflammatory disease (Nomid/Cinca syndrome)
    Medical condition: neonatal onset multisystem inflammatory disease (NOMID/CINCA)
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2019-004101-27 Sponsor Protocol Number: INDIGO Start Date*: 2020-01-15
    Sponsor Name:Sint Maartenskliniek
    Full Title: INDIGO: Comparing pharmacokinetic parameters of golimumab 50 mg and golimumab 100 mg with a prolonged dose interval in patients with a rheumatic disease, a within-subject controlled study’
    Medical condition: rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10037160 Psoriatic arthritis LLT
    21.1 10028395 - Musculoskeletal and connective tissue disorders 10071400 Axial spondyloarthritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004488-33 Sponsor Protocol Number: Prada2500? Start Date*: 2020-01-30
    Sponsor Name:Niels Bang
    Full Title: Botox injektion in the hip joint for pain relief and diagnosis of pain lokalisation.
    Medical condition: Patients with hip pain 6 month after operation with periacetabular osteotomi for dysplastic hip.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10063175 Hip dysplasia LLT
    20.0 100000004859 10033432 Pain in hip LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002516-85 Sponsor Protocol Number: 01-2011 Start Date*: 2011-10-20
    Sponsor Name:A.O. UNIVERSITARIA INTEGRATA DI VERONA
    Full Title: Open-label study to evaluate the efficacy and tolerability of orally administered rosiglitazone in patients with progressive bone Fibrodysplasia (FOP)
    Medical condition: Fibrodysplasia Ossificans Progressive (FOP) is a rare genetically based disability, characterized by progressive heterotopic ossification, usually associated with congenital malformation of the toes.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028393 Musculoskeletal and connective tissue disorders NEC HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-005060-26 Sponsor Protocol Number: ONU3704 Start Date*: 2012-06-19
    Sponsor Name:Purdue Pharma L.P.
    Full Title: A Randomized, Double-blind, Double-dummy, Placebo-controlled, Active-controlled, Parallel-group, Multicenter Trial of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess the Analgesic Eff...
    Medical condition: Opioid-induced Constipation & Moderate to Severe Chronic Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    17.0 10028395 - Musculoskeletal and connective tissue disorders 10003988 Back pain PT
    17.0 100000004856 10071128 Opioid induced constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-000993-20 Sponsor Protocol Number: TW77 Start Date*: 2014-12-04
    Sponsor Name:Center for Research and Development Uppsala University/County Council of Gävleborg
    Full Title: Dosing of intraarticular triamcinolone hexacetonid for knee synovitis in chronic polyarthritis
    Medical condition: Psoriatic arthritis and rheumatoid arthritis with synovitis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001764-11 Sponsor Protocol Number: PTC124-GD-030-DMD Start Date*: 2020-01-21
    Sponsor Name:PTC Therapeutics, Inc.
    Full Title: A Phase 2 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Ataluren (PTC124®) in Patients Aged ≥2 to <5 Years Old With Nonsense Mutation Dystrophinopathy
    Medical condition: nonsense mutation dystrophinopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10013801 Duchenne muscular dystrophy PT
    20.0 10010331 - Congenital, familial and genetic disorders 10059117 Becker's muscular dystrophy PT
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-006244-73 Sponsor Protocol Number: EC11-387 Start Date*: 2012-05-29
    Sponsor Name:Instituto Aragonés de Ciencias de la Salud
    Full Title: Evaluation of the efficacy of memantine in the treatment of fibromyalgia: a double-blind randomized control clinical trial.
    Medical condition: Fibromyalgia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002896-17 Sponsor Protocol Number: V1.17.05.2013 Start Date*: Information not available in EudraCT
    Sponsor Name:Orthopädisches Spital Speising
    Full Title: Functional evaluation of two therapy concepts: dynamic orthoses and BoNT
    Medical condition: Infantile cerebral palsy
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003982-32 Sponsor Protocol Number: UCA-01-EC/13/ART Start Date*: 2013-12-26
    Sponsor Name:Arthroscopic Surgery Unit
    Full Title: Pilot study to evaluate combination of intraosseous with intra-articular infiltrations of plasma rich in growth factors (PRGF®-Endoret®) in the treatment of knee osteoarthritis.
    Medical condition: Knee osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001383-31 Sponsor Protocol Number: 13-H-1 Start Date*: 2015-02-24
    Sponsor Name:Witten-Herdecke University
    Full Title: Hypericum perforatum to improve post-operative Pain Outcome after monosegmental Spinal microdistectomy
    Medical condition: Post-op pain Outcome after monosegmental Spinal microdistectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000870-36 Sponsor Protocol Number: 1447 Start Date*: 2015-03-26
    Sponsor Name:Maxima Medical center
    Full Title: Epiphysiodesis for adolescents; what is the most effective postoperative pain treatment? An RCT
    Medical condition: expected excessive body heigth
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000578-37 Sponsor Protocol Number: NL50679.068.15 Start Date*: 2015-05-20
    Sponsor Name:Maastricht University Medical Centre+
    Full Title: The effect of Nandrolone Decanoate Injection and Leucine Supplementation on Muscle Loss During Immobilisation
    Medical condition: Muscle disuse atrophy
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001303-36 Sponsor Protocol Number: EMH-PRP-2013 Start Date*: 2013-10-31
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
    Full Title: Intrarticular injections of platelet-rich plasma in pain?s treatment of the Osteoarthritic Knee
    Medical condition: Pain?s treatment of the Osteoarthritic Knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003238-29 Sponsor Protocol Number: BRN-C-2015-03 Start Date*: 2016-04-06
    Sponsor Name:Fundación Sociedad Española de Médicos de Atención Primaria (SEMERGEN)
    Full Title: Pilot phase II clinical trial, randomized, double-blind, controlled, single-center study to evaluate the efficacy and safety of Solanum malacoxylon 9CH in patients with calcific tendinitis of shoulder
    Medical condition: Calcific tendinitis of shoulder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-002351-42 Sponsor Protocol Number: VIB4920.P0.S1 Start Date*: 2020-01-13
    Sponsor Name:Viela Bio, Inc.
    Full Title: An Observational, Follow-on Study to the MEDI4920 (D5100C00002) Study to Evaluate the Duration of Clinical and Pharmacodynamic Efficacy of 12 weeks of Treatment with VIB4920 in Subjects with Modera...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004870 10039075 Rheumatoid arthritis and associated conditions HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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