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Clinical trials for Shock

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    318 result(s) found for: Shock. Displaying page 4 of 16.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-010104-28 Sponsor Protocol Number: 2008-262 Start Date*: 2009-07-06
    Sponsor Name:Dept. of Intensive Care, Rigshospitalet
    Full Title: Effects of hydroxyethyl starch 130/0.4 compared to a balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis
    Medical condition: Severe sepsis or septic shock
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10040070 Septic shock PT
    13.1 10021881 - Infections and infestations 10053879 Sepsis syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) FI (Completed) IS (Completed)
    Trial results: View results
    EudraCT Number: 2016-002195-27 Sponsor Protocol Number: AC101 Start Date*: 2016-07-08
    Sponsor Name:University of Tartu
    Full Title: Pharmacokinetics and tissue penetration of amoxicillin/clavulanic acid in patients with sepsis and septic shock
    Medical condition: Sepsis and septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005253-30 Sponsor Protocol Number: 9876543123xz Start Date*: 2006-12-22
    Sponsor Name:Queen Mary's School of Medicine & Dentistry, University of London
    Full Title: Study of the effects of different targets for perfusion pressure on tissue perfusion and oxygenation in patients suffering from septic shock
    Medical condition: Septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003539-56 Sponsor Protocol Number: 1.01 Start Date*: 2006-11-10
    Sponsor Name:Medical University of Vienna, Department of Internal Medicine IV
    Full Title: Simvastatin in patients with septic shock
    Medical condition: Septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004442-16 Sponsor Protocol Number: cro524 Start Date*: 2006-11-29
    Sponsor Name:Imperial College London
    Full Title: Modulation of lung injury complicating lung resection
    Medical condition: Acute respiratory distress syndrome, Acute Lung Injury, Ventilator-Induced Lung Injury
    Disease: Version SOC Term Classification Code Term Level
    8.1 10001052 Acute respiratory distress syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-002022-20 Sponsor Protocol Number: NL61945.029.17 Start Date*: 2017-07-27
    Sponsor Name:VU University Medical Center
    Full Title: The effect of inspiratory oxygen fraction on the ratio of partial arterial oxygen pressure and inspiratory oxygen fraction (PaO2/FiO2 ratio) in mechanically ventilated patients with and without mil...
    Medical condition: We investigate the PaO2/FiO2 ratio in patients without and with mild to moderate ARDS
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10003083 ARDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002494-28 Sponsor Protocol Number: 6 Start Date*: 2023-05-18
    Sponsor Name:Consorcio Centro de Investigacion Biomedica en Red, (CIBER)
    Full Title: Randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy of intravenous metoprolol in patients with Acute Respiratory Distress Syndrome (ARDS)
    Medical condition: Intensive Care Unit patients with Acute Respiratory Distress Syndrome (ARDS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10003083 ARDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005883-78 Sponsor Protocol Number: CHRD1520 Start Date*: 2021-02-05
    Sponsor Name:Hospital Center rené Dubos
    Full Title: Comparison of Prednisolone and Dexamethasone on D28 mortality in patients on oxygen therapy with CoViD-19
    Medical condition: Care of severe forms of CoViD-19 from the transitional phase and the onset of the inflammatory phase with corticosteroids
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10084270 SARS-CoV-2 acute respiratory disease LLT
    23.0 10021881 - Infections and infestations 10084272 SARS-CoV-2 infection LLT
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    21.1 100000004855 10042839 Syndrome respiratory distress adult LLT
    23.1 10021881 - Infections and infestations 10084401 COVID-19 respiratory infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-006644-27 Sponsor Protocol Number: CARR-ARDS-2021 Start Date*: 2023-02-28
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA UDINE
    Full Title: Efficacy and safety of anakinra in non-COVID-19 related ARDS. ESKA study.
    Medical condition: Acute respiratory distress syndrome (ARDS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10003083 ARDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005306-25 Sponsor Protocol Number: Pioneer Start Date*: 2021-09-15
    Sponsor Name:OSPEDALE SAN RAFFAELE
    Full Title: PIrfenidone to prevent fibrOsis in ARDS. A RaNdomizEd controllEd tRial (PIONEER) GR-2019-12371063
    Medical condition: Acute respiratory distress syndrome (ARDS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10003083 ARDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-002913-16 Sponsor Protocol Number: 0135-0347 Start Date*: 2020-11-26
    Sponsor Name:SCS Boehringer Ingelheim Comm. V
    Full Title: The TRISTARDS trial - ThRombolysIS Therapy for ARDS A Phase IIb/III operationally seamless, open-label, randomised, sequential, parallel-group adaptive study to evaluate the efficacy and safety of ...
    Medical condition: Acute respiratory distress syndrome caused by Covid-19
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10001052 Acute respiratory distress syndrome PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Prematurely Ended) AT (Ongoing) PT (Completed) NL (Completed) FR (Completed) DK (Prematurely Ended) IT (Prematurely Ended) PL (Completed) RO (Ongoing) ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-001270-41 Sponsor Protocol Number: CPRC2015/HSNORDOB-AUCHET/YB Start Date*: 2019-07-17
    Sponsor Name:CHRU NANCY
    Full Title: Norepinephrine alone vs Norepinephrine and Dobutamine in cardiogenic shock : a randomised, opened, cross-over study. Heart SHOCK-NORDOB Study
    Medical condition: Cardiogenic Shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001430-35 Sponsor Protocol Number: 35RC19_8860_FLUDROSEPSIS Start Date*: 2021-04-21
    Sponsor Name:CHU Rennes
    Full Title: Evaluation of the hemodynamic effects of fludrocortisone on the pressive response to norepinephrine in patients in septic shock
    Medical condition: septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-003801-24 Sponsor Protocol Number: P160925J Start Date*: 2019-11-06
    Sponsor Name:Assistance Publique - Hôpitaux de Paris
    Full Title: A multicenter, prospective, randomized, placebo-controlled, double-blind, multi-arm, multi-stage clinical trial of Ivabradine for heart Rate control In Septic shock
    Medical condition: Trial subjects are adult patients with septic shock.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-005551-36 Sponsor Protocol Number: NL79416.018.21 Start Date*: 2022-08-05
    Sponsor Name:
    Full Title: Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients with Cardiogenic Shock from Acute Myocardial Infarction: A Multicenter Randomized...
    Medical condition: Myocardial infarction related cardiogenic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-001276-15 Sponsor Protocol Number: PI2020_843_0027 Start Date*: 2020-06-18
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Does high-dose vitamin B3 supplementation prevent major adverse kidney events during septic shock? A multicenter randomized controlled study.
    Medical condition: adverse kidney events during septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-000769-13 Sponsor Protocol Number: AP SEP 02-02 Start Date*: 2006-06-13
    Sponsor Name:AM-Pharma
    Full Title: A double-blind, randomized, placebo-controlled study to investigate the clinical efficacy and safety of two doses of Alkaline Phosphatase administered for three days in patients with severe sepsi...
    Medical condition: Severe sepsis and septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-002491-14 Sponsor Protocol Number: Sepsis_IFNg Start Date*: 2012-11-08
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The effects of interferon-gamma on sepsis-induced immunoparalysis, a randomised double-blind placebo-controlled pilot (Phase IIIb) study
    Medical condition: Sepsis-induced immunoparalysis (SIRS, Sepsis, Septic shock)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10062357 SIRS LLT
    14.1 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    14.1 10021428 - Immune system disorders 10061598 Immunodeficiency PT
    14.1 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000136-17 Sponsor Protocol Number: Target_ZKSJ0085 Start Date*: 2016-08-22
    Sponsor Name:Friedrich Schiller University Jena
    Full Title: Prospective, randomized, multicenter clinical trial on the impact of Therapeutic Drug Monitoring (TDM) of piperacillin on organ functions and survival in the treatment of severe sepsis or septic shock
    Medical condition: Patients with a severe sepsis oder a septic shock treatet with piperacillin/tazobactam
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005112-15 Sponsor Protocol Number: TARTARE-2S-01 Start Date*: 2016-09-29
    Sponsor Name:Inselspital, Universitätspital Bern
    Full Title: TARGETED TISSUE PERFUSION VERSUS MACROCIRCULATORY-GUIDED STANDARD CARE IN PATIENTS WITH SEPTIC SHOCK (TARTARE-2S)
    Medical condition: Critically ill adult patients with septic shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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