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Clinical trials for Side effects

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,084 result(s) found for: Side effects. Displaying page 4 of 105.
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    EudraCT Number: 2013-003790-10 Sponsor Protocol Number: 1.0 Start Date*: 2013-10-23
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: DEXMEDETOMIDINE FOR PERIPHERAL NERVE BLOCKADE: A DOSE-FINDING STUDY IN VOLUNTEERS
    Medical condition: 24 Volunteers recieve an ultrasound guided ulnar nerve block, and apparted into 4 groups. Group 1 receives 3ml Ropivacaine 0.75% without adjuvants. Group 2-4 receives 3ml Ropivacain 0.75% with thre...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002471-18 Sponsor Protocol Number: Start Date*: 2019-01-18
    Sponsor Name:Imperial College London
    Full Title: The clinical effectiveness and cost effectiveness of clozapine for inpatients with borderline personality disorder: randomised controlled trial
    Medical condition: Borderline Personality Disorder
    Disease: Version SOC Term Classification Code Term Level
    21.1 10037175 - Psychiatric disorders 10006034 Borderline personality disorder PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2015-003049-24 Sponsor Protocol Number: PHY201501 Start Date*: 2016-07-27
    Sponsor Name:Uppsala University, Department of Medical Sciences
    Full Title: The Precision Hypertension Care study
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-005124-24 Sponsor Protocol Number: 6378707817 Start Date*: 2018-01-31
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: Therapeutic Drug Monitoring guided tamoxifen dosing: a feasibility study in patients with hormone positive breast cancer
    Medical condition: Hormone positive breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003453-18 Sponsor Protocol Number: RH-2015-200 Start Date*: 2015-11-25
    Sponsor Name:Rigshospitalet
    Full Title: A Randomized, Single-blinded, Cross-over Study investigating the Non-inferiority of Efficacy and Safety of HyQvia in comparison with Conventional Subcutaneous Ig Therapy in Multifocal Motor Neuropa...
    Medical condition: Multifocal Motor Neuropathy (MMN)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10064135 Polyneuropathy chronic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-011248-21 Sponsor Protocol Number: Start Date*: 2009-06-29
    Sponsor Name:
    Full Title: het optimaliseren van de voorbereiding voor sigmoidoscopie in de regio; Moviprep versus Bisacodyl/klysma, een enkelblind gerandomiseerd onderzoek
    Medical condition: Bowel preparation for sigmoidoscopy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004277-17 Sponsor Protocol Number: 2008/2 Start Date*: 2010-05-10
    Sponsor Name:GlobiFer International bvba
    Full Title: The effectiveness and tolerability of GlobiFer (haem iron) tablets compared to ferrous sulphate tablets in inflammatory bowel disease: a randomised-controlled trial.
    Medical condition: Anaemia in inflammatory bowel disease
    Disease:
    Population Age: Adolescents, Under 18, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-003420-33 Sponsor Protocol Number: NL78216 Start Date*: 2021-12-13
    Sponsor Name:Leiden University Medical Center
    Full Title: Tacrolimus versus mycophenolate for AutoImmune hepatitis patients with incompLete response On first line therapy: a Randomized trial (TAILOR study)
    Medical condition: Autoimmune hepatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004732-11 Sponsor Protocol Number: Start Date*: 2018-01-19
    Sponsor Name:University of Oxford
    Full Title: Preventing meningitis in young people after infant immunisation: effect of a single meningococcal 4CMenB vaccine booster over 10 years of age
    Medical condition: Meningococcus group B disease, which can cause a variety of symptoms. The most serious of these are meningitis, and septicaemia (also known as blood poisoning).
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-000899-33 Sponsor Protocol Number: rescue RTX Start Date*: 2011-08-09
    Sponsor Name:Department of Endocrinology, Sahlgrenska University Hospital
    Full Title: Rituximab (RTX) therapy in steroid resistant patients or patients relapsing after intravenous steroids with active TAO Rescue RTX
    Medical condition: Thyroid associated opthalmopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-004255-36 Sponsor Protocol Number: Cesar Start Date*: 2020-10-05
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Cesar - an open, randomized controlled phase II study, comparing Naltrexon and Fluoxetin treating Compulsive Sexual Behavior Disorder.
    Medical condition: Compulsive Sexual Behavior Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001101-22 Sponsor Protocol Number: PURE Start Date*: 2021-08-23
    Sponsor Name:Amsterdam UMC
    Full Title: Study to evaluate the efficacy and side effects of Envarsus in patients who had a kidney transplantation
    Medical condition: Kidney transplant immunosupression for patients with CYP3A5*1 gene variance
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021428 - Immune system disorders 10023439 Kidney transplant rejection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-001861-33 Sponsor Protocol Number: P19.050 Start Date*: 2019-07-17
    Sponsor Name:Leiden University Medical Center
    Full Title: Cannabis-opioid interaction in the treatment of fibromyalgia pain – an open label proof-of-concept study
    Medical condition: Chronic fibromyalgia pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002769-44 Sponsor Protocol Number: ESAP Start Date*: 2015-09-28
    Sponsor Name:Medical University of Graz
    Full Title: Efficacy and safety of an accelerated outpatient protocol for hymenoptera venom immunotherapy
    Medical condition: Immunotherapy against systemic anaphylactic sting reactions
    Disease: Version SOC Term Classification Code Term Level
    21.1 10021428 - Immune system disorders 10001749 Allergy to sting PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-001761-11 Sponsor Protocol Number: 300488 Start Date*: 2015-08-31
    Sponsor Name:The Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital
    Full Title: Lymphatic dysfunction as a cause of calcium channel blocker oedema in post-menopausal women
    Medical condition: Calcium channel antagonist induced peripheral edema in post-menopausal women. We hypothesize that this condition is partly due to impaired lymphatic function in these patients.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004867 10067033 Drug side effect LLT
    18.0 100000004867 10034570 Peripheral edema LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-004074-93 Sponsor Protocol Number: EP005 Start Date*: 2005-03-01
    Sponsor Name:EpiTan Limited
    Full Title: A Pilot, Phase II, Open, Controlled Study to Evaluate the Safety, Tolerability and Efficacy of a Subcutaneous Implant of Melanotan in Patients Suffering from Recurrent Polymorphous Light Eruption.
    Medical condition: Polymorphous Light Eruption (PMLE)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005271-42 Sponsor Protocol Number: SM1-04 Start Date*: 2005-04-13
    Sponsor Name:Dept. of Anaestesiology, University hospital in Glostrup
    Full Title: Effect of paracetamol versus paracetamol combined with pregabalin versus paracetamol combined with pregabalin and dexamethason on pain and opioid requirements in patients scheduled for abdominal hy...
    Medical condition: Women scheduled for abdominal hysterectomy needs postoperative pain treatment, i.e. morphine. Morphine has side-effects: nausea, vomiting, sedation and dizziness. These side-effects are of course u...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002341-20 Sponsor Protocol Number: PLAF1003 Start Date*: 2008-07-10
    Sponsor Name:Queen Charlotte's and Chelsea Hospital
    Full Title: Randomized controlled trial comparing the effect of carbetocin vs syntocinon and ergometrine on postpartum haemorrhage in patients undergoing elective caesarean section
    Medical condition: Clinical efficacy comparing ( 2 drugs) carbetocin Vs syntocinon and ergometrine
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003941-41 Sponsor Protocol Number: ABR46374 Start Date*: 2013-11-07
    Sponsor Name:Medisch Spectrum Twente
    Full Title: Reversibility of pulmonary function after inhaling salbutamol in different doses in standard and forward leaning body posture in asthmatic children
    Medical condition: Asthma
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001269-10 Sponsor Protocol Number: Doc-Pred Start Date*: 2016-07-14
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: A pharmacokinetic study of Docetaxel and Prednisone in men with metastatic castration-resistant or hormone-sensitive prostate cancer.
    Medical condition: Metastatic prostate cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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