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Clinical trials for Tolerability

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    14,030 result(s) found for: Tolerability. Displaying page 4 of 702.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2011-001342-15 Sponsor Protocol Number: CACZ885H2361E1 Start Date*: 2011-09-26
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 36-week open-label extension study of CACZ885H2361 on the safety and tolerability of canakinumab 150 mg s.c. pre-filled syringe (PFS) in treating acute gouty arthritis flares in frequently flarin...
    Medical condition: Evaluate the long-term safety, tolerability and immunogenicity of canakinumab 150 mg s.c. administered as pre-filled syringe (PFS).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10018628 Gout acute LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) DE (Completed) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011843-38 Sponsor Protocol Number: STEG-CORP_111804 Start Date*: 2009-12-07
    Sponsor Name:Grachtenhaus-Apotheke, Inh. Klaus Stegemann e.K.
    Full Title: Documentation of the efficacy and tolerability of intravesically applied oxybutynin solution in adult patients with detrusor hyperactivity caused by neurological disorder
    Medical condition: Detrusor hyperactivity caused by neurological dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10061011 Bladder disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000461-12 Sponsor Protocol Number: CBYM338X2204 Start Date*: 2013-05-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double blind, placebo controlled, multi-centre study to assess the pharmacodynamics, pharmacokinetics, safety and tolerability of BYM338 in chronic obstructive pulmonary disease patie...
    Medical condition: Cachexia associated with Chronic Obstructive Pulmonary Disease (COPD) GOLD stage II to IV
    Disease: Version SOC Term Classification Code Term Level
    16.0 10027433 - Metabolism and nutrition disorders 10006895 Cachexia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-001584-22 Sponsor Protocol Number: VDM/032711 Start Date*: 2013-09-16
    Sponsor Name:Gerolsteiner Brunnen GmbH & Co. KG
    Full Title: Pilot study with St. Gero for heartburn
    Medical condition: Functional dyspeptic complaints, particularly heartburn (at least 3 months prior to study start, at least twice per week)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004856 10019326 Heartburn LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002202-30 Sponsor Protocol Number: R207910BAC2001 Start Date*: 2004-10-18
    Sponsor Name:Tibotec Pharmaceuticals Ltd.
    Full Title: An open label study to evaluate the effects on Mycobacterium tuberculosis, safety, tolerability and pharmacokinetics of single doses of R207910, in treatment naive patients with mycobacterium tuber...
    Medical condition: Tuberculosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001179-21 Sponsor Protocol Number: MKC-TI-010 Start Date*: 2005-01-03
    Sponsor Name:MannKind Corporation
    Full Title: A four year, safety and tolerability, open-label, 'follow on' trial evaluating Technosphere®/Insulin in subjects with type 2 diabetes mellitus.
    Medical condition: To evaluate the safety and tolerability of inhaled Technosphere®/Insulin in subjects with type 2 diabetes.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016317-20 Sponsor Protocol Number: SCA_LITIO_12 Start Date*: 2009-10-26
    Sponsor Name:UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
    Full Title: PILOT STUDY TO ASSESS SAFETY AND TOLERABILITY OF LITHIUM ON SPINOCEREBELLAR ATAXIA OF TYPE 2
    Medical condition: Spinocerebellar ataxia type 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031722 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007033-41 Sponsor Protocol Number: 1200 Start Date*: Information not available in EudraCT
    Sponsor Name:Hephata-Klinik
    Full Title: Pilot study on therapeutic efficacy of modafinil in idiopathic hypersomnie
    Medical condition: To test the efficacy, tolerability and safety of modafinil for the treatment of of excessiv daytime sleepiness in patients with idiopathic hypersomnia without long sleep time.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000283-27 Sponsor Protocol Number: VX04-765-201 Start Date*: 2004-07-19
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Pilot Open-Label Study to Investigate the Safety and Anti-inflammatory Effects of VX-765, an Orally Administered Interleukin-1β Converting Enzyme Inhibitor, in Patients with Muckle-Wells Syndrome
    Medical condition: Muckle-Wells syndrome
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-004635-20 Sponsor Protocol Number: P1605NY Start Date*: 2017-03-24
    Sponsor Name:G. Pohl-Boskamp GmbH & Co. KG
    Full Title: A monocentric, randomized, controlled, investigator-blind trial to evaluate the efficacy and safety of an investigational medical device (PB790) in subjects with head lice.
    Medical condition: Headlice infestation
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10019197 Head lice LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001510-40 Sponsor Protocol Number: TM-ME3710/304 Start Date*: 2005-07-12
    Sponsor Name:TEDEC MEIJI FARMA, S.A.
    Full Title: Prospective randomized study to assess the efficacy and tolerability of ferrimannitol ovoalbumin compared to ferrous sulphate in the treatment of iron deficiency anaemia
    Medical condition: Iron deficiency anaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000994-19 Sponsor Protocol Number: GER/026115 Start Date*: 2016-07-08
    Sponsor Name:Gerolsteiner Brunnen GmbH & Co. KG
    Full Title: Doubleblind, randomised, placebo-controlled clinical trial to evaluate the safety and efficacy of Gerolsteiner Heilwasser in NERD patients with heartburn
    Medical condition: functional dyspeptic complaints, particularly heartburn (at least 3 months prior to study start, on at least 4 days per week)
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004856 10019326 Heartburn LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001256-36 Sponsor Protocol Number: FACH/023212 Start Date*: 2013-06-14
    Sponsor Name:Fachingen Heil- und Mineralbrunnen GmbH
    Full Title: Pilot study with Staatl. Fachingen STILL for functional dyspepsia (particularly heartburn)
    Medical condition: Functional dyspeptic complaints, particularly heartburn (at least 3 months prior to study start, at least twice per week)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004856 10019326 Heartburn LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000061-11 Sponsor Protocol Number: GAA 5233 Start Date*: 2006-04-03
    Sponsor Name:BODE Chemie GmbH & Co
    Full Title: Prospective randomized controlled double-blind multicentric phase III study to evaluate antiseptic efficacy and local tolerability of Stellisept mucosa in patients with chronic wounds
    Medical condition: ulcus cruris
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000438-16 Sponsor Protocol Number: LT2347-PIV-02/20 Start Date*: 2020-07-29
    Sponsor Name:Laboratoires Théa S.A.S
    Full Title: RANDOMIZED SINGLE-BLIND CLINICAL TRIAL TO STUDY THE TOLERABILITY, EFFICACY, QUALITY OF LIFE, AND ADHERENCE OF FIXAPROST® COMPARED TO GANFORT® P IN PATIENTS WITH OPEN-ANGLE GLAUCOMA AND/OR OCULAR HY...
    Medical condition: Open angle glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000871-33 Sponsor Protocol Number: 8407040 Start Date*: 2004-12-02
    Sponsor Name:Apogepha Arzneimittel GmbH
    Full Title: Propiverine hydrochloride extended release (ER): Tolerability in patients with LUTS and BPS/BPH A randomised, double-blind, placebo-controlled, multi-centre clinical trial
    Medical condition: Patients suffering from LUTS (Lower Urinary Tract Symptoms) and BPS/BPH (Benign Prostatic Syndrome/Benign Prostatic Hyperplasia
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002276-42 Sponsor Protocol Number: 61/O4/OX/Rh Start Date*: 2004-12-13
    Sponsor Name:IVAX Pharmaceuticals s.r.o.
    Full Title: Tolerability and safety of Oxamet® in patients with acute rhinitis
    Medical condition: Acute rhinitis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002290-21 Sponsor Protocol Number: GMX07 Start Date*: 2014-04-30
    Sponsor Name:Bio Products Laboratory Limited
    Full Title: A Phase III, Multicenter, Open-label, Randomized, Two-Period, Crossover Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary...
    Medical condition: Primary immunodeficiency diseases
    Disease: Version SOC Term Classification Code Term Level
    17.1 10010331 - Congenital, familial and genetic disorders 10064859 Primary immunodeficiency syndrome PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2022-003318-35 Sponsor Protocol Number: VX22-264-101 Start Date*: 2023-09-25
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-264 in Subjects With Type 1 Diabetes Mellitus
    Medical condition: Type 1 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001678-40 Sponsor Protocol Number: CACZ885N2301E2 Start Date*: 2017-05-15
    Sponsor Name:Novartis pharma AG
    Full Title: An extension study of safety of canakinumab in Japanese patients with periodic fever syndromes
    Medical condition: Three disease of periodic fever syndromes, TNF receptor Associated Periodic Syndrome (TRAPS), Hyper IgDSyndrome (HIDS)/ Mevalonate Kinase Deficiency (MKD) and Familial Mediterranean Fever (FMF
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10010331 Congenital, familial and genetic disorders SOC
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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