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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44396   clinical trials with a EudraCT protocol, of which   7408   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,396 result(s) found. Displaying page 690 of 2,220.
    «« First « Previous 686  687  688  689  690  691  692  693  694  Next» Last»»
    EudraCT Number: 2017-003414-10 Sponsor Protocol Number: NN9536-4374 Start Date*: 2018-05-09
    Sponsor Name:Novo Nordisk A/S
    Full Title: Effect and safety of semaglutide 2.4 mg once-weekly in subjects with overweight or obesity and type 2 diabetes
    Medical condition: 1. Obesity 2. Diabetes Mellitus, Type 2
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    20.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-003819-71 Sponsor Protocol Number: DX-88/14 Start Date*: 2006-11-23
    Sponsor Name:Dyax Corp
    Full Title: EDEMA3: Evaluation of DX-88’s Effects in Mitigating Angioedema A double-blind, placebo-controlled study followed by a repeat dosing phase to assess the efficacy and safety of DX-88 (recombinant pl...
    Medical condition: Hereditary Angioedema
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004480-39 Sponsor Protocol Number: DPP4-Hypo Start Date*: 2017-12-22
    Sponsor Name:Profil Institut für Stoffwechselforschung GmbH
    Full Title: DPP-4 inhibition with sitagliptin and the risk for hypoglycaemia in the fasting state in subjects with type 2 diabetes treated to fasting plasma glucose targets with insulin glargine and metformin
    Medical condition: Diabetes mellitus type 2
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004825-25 Sponsor Protocol Number: GF-ICTUS-04 Start Date*: 2006-05-30
    Sponsor Name:Ferrer Internacional
    Full Title: Citicoline in the treatment of acute ischemic stroke. An international randomized multicenter placebo-controlled study. Citicolina en el tratamiento del ictus isquémico agudo. Estudio internaciona...
    Medical condition: Acute ischemic stroke Ictus isquémico agudo
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) PT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005655-13 Sponsor Protocol Number: TRY Start Date*: 2012-10-17
    Sponsor Name:University of Cologne
    Full Title: A phase II trial to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small cell lung cancer (NSCLC) with HER2 - overexpression or - amplification or - mutation.
    Medical condition: Advanced non-small cell lung cancer with HER2 - overexpression or - amplification or - mutation
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002987-26 Sponsor Protocol Number: KOLterbutaline Start Date*: 2011-08-24
    Sponsor Name:Bispebjerg Hospital
    Full Title: Effects of high dose terbutaline on physical performance in patients with chronic obstructive pulmonary disease and acute inflammatory response after exercise
    Medical condition: To investigate the effects of terbutaline on repeated exercise performance in patients with chronic obstructive pulmonary disease (COPD). Furthermore to examine the inflammatory response during and...
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-004878-17 Sponsor Protocol Number: 0.1 Start Date*: 2017-07-20
    Sponsor Name:University of Leicester
    Full Title: The Effect of a SGLT2 inhibitor on Glucose flux, Lipolysis and Exercise in type 2 Diabetes
    Medical condition: Type 2 diabetes.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2007-007275-16 Sponsor Protocol Number: InfQ-001 Start Date*: 2008-12-18
    Sponsor Name:Department of Infetious Diseases, Odense University Hospital
    Full Title: Antibiotic treatment in patients hospitalized with an acute exacerbation in chronic obstructive pulmonary disease. Effect of one day of antibiotic treatment compared t0 6 days of antibiotic treatme...
    Medical condition: Acute exacerbation of chronic ostructive pulmonary disease in hospitalized patients. All patients receive "standard of care", and 1 day of intravenous antibiotics. In addition patients are randomiz...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056971 Infective exacerbation of chronic obstructive airways disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012607-26 Sponsor Protocol Number: MIMEB Start Date*: 2009-12-10
    Sponsor Name:University of Cologne
    Full Title: MIMEB - Molecular Imaging with erlotinib and bevacizumab. A Phase II Clinical Trial to Evaluate the Accuracy of FDG-/FLT-PET and DCE-MRI for Early Prediction of Non-Progression in Patients with Adv...
    Medical condition: Patients with Advanced Non Squamous Cell Non Small Cell Lung Cancer (NSCLC), first-line.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10025054 Lung cancer non-small cell stage IIIB LLT
    12.0 10025055 Lung cancer non-small cell stage IV LLT
    12.0 10029515 Non-small cell lung cancer recurrent PT
    12.0 10029521 Non-small cell lung cancer stage IIIB PT
    12.0 10029522 Non-small cell lung cancer stage IV PT
    12.0 10029521 Non-small cell lung cancer stage IIIB LLT
    12.0 10029522 Non-small cell lung cancer stage IV LLT
    12.0 10050017 Lung cancer metastatic LLT
    12.0 10059515 Non-small cell lung cancer metastatic LLT
    12.0 10061873 Non-small cell lung cancer LLT
    12.0 10066490 Progression of non-small cell lung cancer LLT
    12.0 10050017 Lung cancer metastatic PT
    12.0 10059515 Non-small cell lung cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005039-86 Sponsor Protocol Number: IEO S265/505 Start Date*: 2006-05-09
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: A phase II study of Pegylated Liposomal Doxorubicin PLD as preoperative treatment for elderly patients with locally advanced primary breast cancer.
    Medical condition: Locally advanced breast cancer
    Disease: Version SOC Term Classification Code Term Level
    6.1 10057654 PT
    Population Age: Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004614-32 Sponsor Protocol Number: IEO S262/505 Start Date*: 2006-01-20
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: Randomized phase II trial of Budesonide Turbuhaler 800 micrograms/twice daily versus placebo in high-risk population with undetermined lung nodules detected at screening low dose CT scan
    Medical condition: Intermediate biomarker modulation in lung carcinogenesis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10049498 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004828-66 Sponsor Protocol Number: MedOPP112 Start Date*: 2016-07-20
    Sponsor Name:Medica Scientia Innovation Research (MedSIR ARO)
    Full Title: A phase IIa clinical trial to evaluate the safety and efficacy of osirmertinib (AZD9291) in first-line patients with EGFR mutation-positive locally advanced or metastatic non-small cell lung cancer...
    Medical condition: Patients diagnosed with stage IIIB or IV non-small cell lung cancer carrying the EGFR activating mutation and confirming concomitant T790M mutation during screening who have not received prior trea...
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029521 Non-small cell lung cancer stage IIIB PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059515 Non-small cell lung cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015499-88 Sponsor Protocol Number: KKSH-067 Start Date*: 2010-02-09
    Sponsor Name:Martin-Luther-Universität Halle-Wittenberg
    Full Title: Senkung einer erhöhten Herzfrequenz durch Ivabradin bei Patienten mit Multiorgandysfunktionssyndrom.
    Medical condition: Patienten mit MODS (Multiorgandysfunktionssyndrom)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001894-41 Sponsor Protocol Number: AS0006 Start Date*: 2015-10-16
    Sponsor Name:UCB BIOSCIENCES GmbH
    Full Title: PHASE 3, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY TO EVALUATE EFFICACY AND SAFETY OF CERTOLIZUMAB PEGOL IN SUBJECTS WITH ACTIVE AXIAL SPONDYLOARTHRITIS (AXSPA) WITHOUT X-RAY ...
    Medical condition: ACTIVE AXIAL SPONDYLOARTHRITIS (AXSPA) WITHOUT X-RAY EVIDENCE OF ANKYLOSING SPONDYLITIS (AS) AND OBJECTIVE SIGNS OF INFLAMMATION
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10076297 Non-radiographic axial spondyloarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-004502-26 Sponsor Protocol Number: DL/HL/09/18 Start Date*: 2019-07-18
    Sponsor Name:Przedsiębiorstwo Produkcji Farmaceutycznej (P.P.F.)HASCO-LEK S.A.
    Full Title: "Randomized, double-blind, cross-over efficacy and safety study based on the pharmacodynamic model of topical use of the new combination gel containing diphenhydramine hydrochloride 20 mg/g and lid...
    Medical condition: Skin inflamatory and allergic lesions inducted by insects bites (i.e. mosquitos) and after contact with plants (i.e.urtica). Decreasing redness, edema, papular urticaria, analgesic, antipriuritic a...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10038198 Redness LLT
    20.0 10018065 - General disorders and administration site conditions 10014210 Edema LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10033474 Pain of skin PT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10018069 General pruritus LLT
    20.0 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10015150 Erythema PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-004219-36 Sponsor Protocol Number: MR-ISB-1 Start Date*: 2013-12-02
    Sponsor Name:Paracelsus Mediznische Privatuniversität, Universitätsklinik für Anästhesiologie, perioperative Medizin und Intensiv
    Full Title: Magnetic Resonance Imaging of Local Anesthetic Distribution: A Comparison of 5 and 15 milliliters of ropivacaine 0.75% for ultrasound guided interscalene plexus blockade
    Medical condition: Surgery of the shoulder and/or upper extremity using interscalene brachial plexus block
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-000827-15 Sponsor Protocol Number: PARROT Start Date*: 2013-05-11
    Sponsor Name:Unità Malattie Neurodegenerative, Ospedale Cardinale Giovanni Panico, Tricase
    Full Title: LATE ONSET PARKINSON’S DISEASE IN SUBJECTS 70 YEARS AND OLDER: POSSIBLE USE OF ROTIGOTINE
    Medical condition: Parkinson disease
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002200-40 Sponsor Protocol Number: MEV90-TQL-ZUH Start Date*: 2019-07-04
    Sponsor Name:Anæstesiologisk afdeling, Sjællands Universitetshospital, Roskilde
    Full Title: The minimal effective volume (MEV90) of ropivacaine 0.75 % for ultrasound-guided transmuscular quadratus lumborum block for unilateral percutaneous nephrolitotomy – A dose finding study.
    Medical condition: Postoperative pain following percutaneous nephrolithotomy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10059805 Nephrolithotomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000383-27 Sponsor Protocol Number: D1803C00002 Start Date*: 2004-07-28
    Sponsor Name:AstraZeneca AB
    Full Title: A double-blind randomized placebo controlled crossover study of AZD7371 ER 5 mg bid, 20 mg bid and placebo treatment for one week on visceral perception and symptoms in patients with Irritable Bowe...
    Medical condition: Irritable Bowel Syndrome (IBS)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000139-27 Sponsor Protocol Number: A509 1018 Start Date*: 2004-09-14
    Sponsor Name:Pfizer AB
    Full Title: A Phase 3, Double-Blind, Placebo-Controlled, Randomized, Parallel Group, Multicenter Study of the Efficacy, Safety, and Tolerability of Fixed Combination Torcetrapib/Atorvastatin Administered Orall...
    Medical condition: Mixed dyslipidemia (Frederickson Types IIa and IIb)
    Disease: Version SOC Term Classification Code Term Level
    10058108
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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