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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 746 of 2,219.
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    EudraCT Number: 2006-003515-44 Sponsor Protocol Number: ACA-SPAI-04-22 Start Date*: 2006-12-26
    Sponsor Name:FRANCISCO JAVIER BELDA
    Full Title: Cardioprotective effect of sevoflurane versus propofol used during anesthesia and the postoperative period in patients undergoing coronary bypass surgery. Impact on critical care unit stay. A doubl...
    Medical condition: This study will evaluate the cardioprotective effects of sevoflurane versus propofol during anesthesia and sedation of patients undergoing coronary bypass surgery in terms of maintenance of cardiac...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016965-26 Sponsor Protocol Number: 108/140 Start Date*: 2010-12-13
    Sponsor Name:Centro Comunitario de Sangre y Tejidos de Asturias
    Full Title: Ensayo clínico multicéntrico, aleatorizado, abierto para valorar la eficacia y seguridad del tratamiento de úlceras venosas crónicas con injertos cutáneos cultivados
    Medical condition: Úlceras venosas crónicas
    Disease: Version SOC Term Classification Code Term Level
    9 10047259 Venous ulcer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-017776-24 Sponsor Protocol Number: NL30577.031.09 Start Date*: 2010-03-03
    Sponsor Name:
    Full Title: A pilot study evaluating response to induction chemotherapy with oxaliplatin, capecitabine and bevacizumab in patients with extensive peritoneal carcinomatosis of colorectal origin.
    Medical condition: Induction chemotherapy for Peritoneal Carcinomatosis of Colorectal Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-018123-32 Sponsor Protocol Number: DIM20EXT Start Date*: 2010-06-07
    Sponsor Name:Medivation, Inc
    Full Title: HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease
    Medical condition: Huntington disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10020469 Huntington's chorea LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed) GB (Completed) NL (Completed) SE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016525-34 Sponsor Protocol Number: 28431754DIA3006 Start Date*: 2010-04-21
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo and Active-Controlled, 4-Arm, Parallel-Group, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-28431754 (Canagliflozin) Compared with...
    Medical condition: Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067585 Type 2 diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) BG (Completed) PT (Prematurely Ended) PL (Completed) SK (Completed) CZ (Completed) EE (Completed) SE (Completed) GR (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017472-25 Sponsor Protocol Number: DKKS_09_2009 Start Date*: 2010-06-24
    Sponsor Name:Universitätsklinikum Schleswig-Holstein, Campus Lübeck
    Full Title: „Duplex-kontrollierte, katheter-gestützte Schaumsklerosierung (DKKS) von Krampfadern in Kombination mit Tumeszenzlösungsapplikation (TLA)“ (“Catheter-directed foam sclerotherapy of varicose veins...
    Medical condition: Erwachsene mit einer Stammvarikose der V. saphena magna, bei der die medizinische Indikation zur operativen Sanierung vorliegt. I83.9, I83.1, I83.2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017603-28 Sponsor Protocol Number: PG-APRE1 Start Date*: 2010-02-03
    Sponsor Name:AZIENDA OSPEDALIERA DI PERUGIA
    Full Title: Aprepitant for prevention of acute and delayed nausea and vomiting: a phase III, double-blind, randomized, palcebo-controlled trial in patients receiving a high-emetogenic dose of cyclophosphamide ...
    Medical condition: Multiple myeloma, Hodgkin lymphoma, Non-Hodgkin lymphoma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025319 HLGT
    9.1 10025322 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017477-38 Sponsor Protocol Number: MEK112110 Start Date*: Information not available in EudraCT
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: An Open-Label, Dose-Escalation, Phase IB/ II Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of the MEK Inhibitor GSK1120212 in Combination with Oral Evero...
    Medical condition: Solid Tumors
    Disease: Version SOC Term Classification Code Term Level
    12.1 10059515 Non-small cell lung cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015737-73 Sponsor Protocol Number: 2009-015737-73 Start Date*: 2010-02-04
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Single-step antigen loading and TLR activation of dendritic cells by mRNA electroporation for vaccination in stage III and IV melanoma patients
    Medical condition: Our study population consists of melanoma patients, with proven expression of melanoma associated tumor antigens gp100 and tyrosinase. Melanoma patients with regional lymph node metastasis in whom ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2009-014834-22 Sponsor Protocol Number: CAIN457C2302 Start Date*: 2010-07-06
    Sponsor Name:Novartis Farmacéutica, S.A.
    Full Title: Estudio Fase III, multicéntrico, aleatorizado con doble enmascaramiento, controlado con placebo, de determinación de dosis y 28 semanas de duración, para evaluar AIN457 frente a placebo en la induc...
    Medical condition: determinación de dosis y 28 semanas de duración, para evaluar AIN457 frente a placebo en la inducción y mantenimiento de la supresión de la uveítis en adultos con uveítis activa no infecciosa inter...
    Disease: Version SOC Term Classification Code Term Level
    11 10022557 Uveítis intermedia PT
    11 10036370 Uveítis posterior LLT
    11 10033687 Panuveítis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) HU (Prematurely Ended) GB (Completed) DE (Prematurely Ended) FR (Prematurely Ended) IT (Prematurely Ended) GR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-018331-18 Sponsor Protocol Number: ML25243 Start Date*: 2010-05-12
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: A 52 week, Single center, Open-label Study to Evaluate Neutrophil function and survival effects of Tocilizumab (TCZ) in Patients with Active Rheumatoid Arthritis (RA) on Background Non-biologic DMA...
    Medical condition: Adult Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019161-28 Sponsor Protocol Number: BDT-09-ADC004 Start Date*: 2010-04-06
    Sponsor Name:Becton, Dickinson and Company, BD Technologies
    Full Title: A single center, open-label, randomized study examining the glycemic effects of intra-dermal vs. subcutaneous bolus dosing of insulin lispro in patients with type 1 diabetes
    Medical condition: Diabetes mellitus Type I
    Disease: Version SOC Term Classification Code Term Level
    12.1 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018103-40 Sponsor Protocol Number: GLN-CMF-RTP Start Date*: 2010-05-31
    Sponsor Name:David López Vaquero
    Full Title: ENSAYO CLÍNICO ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO PARA EVALUAR EL USO DE LA GLUTAMINA COMO AGENTE PROTECTOR EN LA MUCOSITIS ORAL Y LA RADIODERMITIS INDUCIDA POR LA RADIOTERAPIA Y/O ...
    Medical condition: Mucositis oral asociada a radioterapia o radioquimioterapia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010421-39 Sponsor Protocol Number: TRA112940 Start Date*: 2010-03-10
    Sponsor Name:GlaxoSmithKline
    Full Title: A longitudinal 2-year bone marrow study of eltrombopag olamine (SB-497115-GR) in previously treated adults, with chronic immune (idiopathic) thrombocytopenic purpura (ITP).
    Medical condition: Chronic Idiopathic Thrombocytopenic Purpura
    Disease: Version SOC Term Classification Code Term Level
    15.1 10005329 - Blood and lymphatic system disorders 10021245 Idiopathic thrombocytopenic purpura PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) FR (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-015865-30 Sponsor Protocol Number: PAHFRAC-01 Start Date*: 2010-06-24
    Sponsor Name:Máximo Bernabeu Wittel
    Full Title: ENSAYO CLINICO RANDOMIZADO DOBLE CIEGO DE HIERRO CARBOXIMALTOSA INTRAVENOSO CON O SIN ERITOPOYETINA PARA LA PREVENCIÓN DE TRANSFUSIONES DE CONCENTRADOS DE HEMATÍES EN EL PERIOPERATORIO DE FRACTURA ...
    Medical condition: Pacientes adultos ingresados en el Hospital por fractura de cadera osteoporótica. Adult patients admitted in Hospital for osteoporotic hip fracture
    Disease: Version SOC Term Classification Code Term Level
    11 10020100 Fractura de cadera LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019288-13 Sponsor Protocol Number: MK0974-065 Start Date*: 2010-06-24
    Sponsor Name:Merck, Sharp & Dohme B.V.
    Full Title: A Six Month Phase II/III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of Telcagepant (MK-0974) for Prevention of Menstrually Relat...
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    12.1 10027599 Migraine LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed) GB (Completed) SE (Completed) DE (Completed) FI (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-018624-20 Sponsor Protocol Number: OPM-CIC-G-H-0902 Start Date*: 2010-05-19
    Sponsor Name:University Medical Center Freiburg
    Full Title: Tolerance of virucidal alcohol-based hand rubs - healthy volunteer trial
    Medical condition: Only healthy volunteers are included in this trial. Alcohol-based hand rubs are licensed drugs in Germany. They are indicated to perform hand disinfection by health care workers and are used within...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018917-30 Sponsor Protocol Number: RB01 Start Date*: 2010-04-08
    Sponsor Name:Erasmus Medical Center
    Full Title: A SINGLE-CENTER PHARMACOGENETIC STUDY OF DONOR AND RECIPIENT TO IMPROVE THE EFFICACY AND REDUCE THE NEPHROTOXICITY OF TACROLIMUS AFTER KIDNEY TRANSPLANTATION
    Medical condition: Kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    12.1 10038474 Renal insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011354-18 Sponsor Protocol Number: CiclosporinPro_1_09 Start Date*: 2010-02-16
    Sponsor Name:Universitätsklinikum Essen
    Full Title: Randomised, open-label, comparative phase IV study on the bioavailability of Ciclosporin Pro (Teva) versus Sandimmun® Optoral (Novartis) under fasting versus fed conditions in patients with stable ...
    Medical condition: prophylaxis against renal transplant rejection
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013839-37 Sponsor Protocol Number: HD0803 Start Date*: 2010-03-30
    Sponsor Name:IIL INTERGRUPPO ITALIANO LINFOMI ONLUS
    Full Title: A phase II multi-centre study of MBVD in elderly and/or cardiopathic patients affected by Hodgkin s lymphoma (HL).
    Medical condition: elderly and/or cardiopathic patients affected by Hodgkin s lymphoma (HL).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025319 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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