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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 746 of 2,220.
    EudraCT Number: 2010-019288-13 Sponsor Protocol Number: MK0974-065 Start Date*: 2010-06-24
    Sponsor Name:Merck, Sharp & Dohme B.V.
    Full Title: A Six Month Phase II/III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of Telcagepant (MK-0974) for Prevention of Menstrually Relat...
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    12.1 10027599 Migraine LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed) GB (Completed) SE (Completed) DE (Completed) FI (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-018624-20 Sponsor Protocol Number: OPM-CIC-G-H-0902 Start Date*: 2010-05-19
    Sponsor Name:University Medical Center Freiburg
    Full Title: Tolerance of virucidal alcohol-based hand rubs - healthy volunteer trial
    Medical condition: Only healthy volunteers are included in this trial. Alcohol-based hand rubs are licensed drugs in Germany. They are indicated to perform hand disinfection by health care workers and are used within...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018917-30 Sponsor Protocol Number: RB01 Start Date*: 2010-04-08
    Sponsor Name:Erasmus Medical Center
    Full Title: A SINGLE-CENTER PHARMACOGENETIC STUDY OF DONOR AND RECIPIENT TO IMPROVE THE EFFICACY AND REDUCE THE NEPHROTOXICITY OF TACROLIMUS AFTER KIDNEY TRANSPLANTATION
    Medical condition: Kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    12.1 10038474 Renal insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011354-18 Sponsor Protocol Number: CiclosporinPro_1_09 Start Date*: 2010-02-16
    Sponsor Name:Universitätsklinikum Essen
    Full Title: Randomised, open-label, comparative phase IV study on the bioavailability of Ciclosporin Pro (Teva) versus Sandimmun® Optoral (Novartis) under fasting versus fed conditions in patients with stable ...
    Medical condition: prophylaxis against renal transplant rejection
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013839-37 Sponsor Protocol Number: HD0803 Start Date*: 2010-03-30
    Sponsor Name:IIL INTERGRUPPO ITALIANO LINFOMI ONLUS
    Full Title: A phase II multi-centre study of MBVD in elderly and/or cardiopathic patients affected by Hodgkin s lymphoma (HL).
    Medical condition: elderly and/or cardiopathic patients affected by Hodgkin s lymphoma (HL).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025319 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019091-78 Sponsor Protocol Number: 2009_06 Start Date*: 2010-06-14
    Sponsor Name:University of Oxford
    Full Title: An observational study into the maintenance of seroprotection against Meningococcal serogroup C disease throughout childhood following a single dose of a conjugated Meningococcal serogroup C vaccin...
    Medical condition: Active immunisation of children for the prevention of invasive diseases caused by Neisseria meningitidis serogroup C
    Disease: Version SOC Term Classification Code Term Level
    12.1 10028911 Neisseria meningitidis infection NOS LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017003-28 Sponsor Protocol Number: BD0109 Start Date*: 2010-04-12
    Sponsor Name:BIOGEN-DOMPE` SRL
    Full Title: Relationship between IL-6 and TNF-α polymorphism and flu-like syndrome development in multiple sclerosis patients treated with Interferon-beta 1a i.m. Open label multicentre study
    Medical condition: multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 SOC
    9.1 10012303 HLGT
    9.1 10052785 HLT
    9.1 10063399 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-018309-12 Sponsor Protocol Number: 02-2010 Start Date*: 2010-02-26
    Sponsor Name:Association REDAR, Hôpital Ambroise Paré, Service d'Anesthésie et de Réanimation
    Full Title: Etude bi-centrique, randomisée, en groupes parallèles et double aveugle contre placebo pour évaluer l’efficacité et la sécurité à long terme de la toxine botulique en deux administrations répétées ...
    Medical condition: Painful peripheral neuropathies related to mononeuropathies (eg, traumatic, postherpetic...) or to polyneuropathies (eg, diabetic, idiopathic...)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004126-85 Sponsor Protocol Number: RANRAP-01 Start Date*: 2007-02-22
    Sponsor Name:Dr. Lluis Arias
    Full Title: Ensayo clínico de fase II, prospectivo, abierto, aleatorizado con grupos paralelos y multicéntrico para comparar la seguridad y la eficacia de ranibizumab intravítreo en monoterapia versus la combi...
    Medical condition: PROLIFERACIÓN ANGIOMATOSA RETINIANA (RAP)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006749-15 Sponsor Protocol Number: P-T-06 Start Date*: 2009-03-09
    Sponsor Name:Institut de Recerca Hospital de Sant Pau
    Full Title: NEUROIMAGEN MOLECULAR EN EL TEMBLOR ESENCIAL: ESTUDIO PET MULTITRAZADOR.
    Medical condition: Flumazenilo (N-metil[11C]): evaluacion de la densidad de receptores benzodiacepinicos del complejo GABA en el cerebro humano en condiciones normales y diversas patologias mediante imagenes de tomog...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015776-95 Sponsor Protocol Number: ENM-DA012 Start Date*: 2010-03-24
    Sponsor Name:Universitätsklinik für Innere Medizin, Klinische Abteilung für Endokrinologie und Nuklearmedizin
    Full Title: Effects of vitamin D supplementation in coronary artery disease patients with postchallenge hyperglycemia and vitamin D deficiency on endothelial function and insulin sensivitivity
    Medical condition: subjects with coronary artery disease, postchallenge hyperglycemia and low levels of 24-OH-vitamin D
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016490-16 Sponsor Protocol Number: MeRSO09 Start Date*: 2011-09-01
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Medicina Regenerativa en la Superficie Ocular: Aplicación de terapia celular para la reparación de la superficie ocular mediante amplificación ex vivo de células progenitoras autólogas del limbo es...
    Medical condition: insuficiencia límbica severa unilateral
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013410-26 Sponsor Protocol Number: ML22229 Start Date*: 2010-02-09
    Sponsor Name:ROCHE SAS
    Full Title: An open-label, randomized, multicenter, phase II, comparative, exploratory study on neoadjuvant treatment with trastuzumab plus docetaxel versus trastuzumab plus docetaxel plus bevacizumab accordin...
    Medical condition: early stage HER2 positive breast cancer
    Disease: Version SOC Term Classification Code Term Level
    12.0 10057654 Breast cancer female PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-007182-23 Sponsor Protocol Number: MenOccy/I72P1 Start Date*: 2010-03-16
    Sponsor Name:Health Protection Agency
    Full Title: A phase 2, open-label study of the safety, tolerability and immunogenicity of a Novartis meningococcal B vaccine when administered at a 0, 2, 6 month schedule and of a single dose of Novartis menin...
    Medical condition: The study investigates the ability of the two vaccines to induce protective immunity against meningococcal disease.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-018066-36 Sponsor Protocol Number: SecondLineStudy Start Date*: 2010-05-11
    Sponsor Name:Glaukos Corporation
    Full Title: Evaluación aleatorizada prospectiva en abierto del iStent® (GTS400)frente a dos agentes hipotensores oculares en pacientes con glaucoma primario de ángulo abierto
    Medical condition: Glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004523-19 Sponsor Protocol Number: TIP0305 Start Date*: 2008-02-08
    Sponsor Name:Área de Trasplante y Terapia Celular - Hospital Central de Asturias
    Full Title: Phase II clinical trial to evaluate the efficacy and safety in the use of pancreatic islets cells from cadaver donors for the treatment of Type-I Diabetes Mellitus in renal transplant patients.
    Medical condition: Type-I Diabetes Mellitus in renal trasplant patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10061835 pt
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016026-13 Sponsor Protocol Number: O-ESHAP-LH-2009 Start Date*: 2010-05-18
    Sponsor Name:FUNDACION GELTAMO
    Full Title: Estudio de fase II de uso de anticuerpo monoclonal anti-CD20 (ofatumumab) más ESHAP seguido de trasplante autólogo de progenitores hemopoyéticos para el tratamiento de linfoma de Hodgkin clásico en...
    Medical condition: EL PRESENTE ESTUDIO PROPONE TRATAR PACIENTES CON LINFOMA DE HODGKIN CLASICO REFRACTARIO, EN RESPUESTA PARCIAL O RECAIDA CON QUIMIOTERAPIA SEGUN DOSIS ESTANDAR DE ESHAP EN COMBINACION CON OFATUMUMAB...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10020328 Hodgkin's lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018079-15 Sponsor Protocol Number: IDX-07A-001 Start Date*: 2010-05-03
    Sponsor Name:Idenix Pharmaceuticals, Inc
    Full Title: A Phase I/IIa Study Assessing Single and Multiple Doses of HCV Protease Inhibitor IDX320 in Healthy and Genotype 1 HCV-Infected Subjects
    Medical condition: Healthy Volunteers and Genotype 1 HCV infection
    Disease: Version SOC Term Classification Code Term Level
    12.1 10008912 Chronic hepatitis C LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-012604-92 Sponsor Protocol Number: 05-NEOV-004 Start Date*: 2010-04-19
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: A randomised, double-blind study of the safety and efficacy of Neoven compared to Vaminolact in infants and children requiring long-term parenteral nutrition
    Medical condition: The product is aimed to be used where parenteral nutrition is required. The intended indication is: Supply of essential and non-essential amino acids as part of Parenteral Nutrition for infants an...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10051284 Parenteral nutrition LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016932-11 Sponsor Protocol Number: 15051982 Start Date*: 2010-03-08
    Sponsor Name:BOOG Study Center B.V
    Full Title: Phase III randomized trial with neoadjuvant chemotherapy (TAC) with or without zoledronic acid for patients with HER2-negative breast cancer.
    Medical condition: Patients with locally advanced or large resectable HER2-negative breast cancer
    Disease: Version SOC Term Classification Code Term Level
    12.1 10006195 Breast cancer NOS stage II LLT
    12.1 10006196 Breast cancer NOS stage III LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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