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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,338 result(s) found. Displaying page 746 of 2,217.
    «« First « Previous 742  743  744  745  746  747  748  749  750  Next» Last»»
    EudraCT Number: 2008-003322-42 Sponsor Protocol Number: UGL-OR0801 Start Date*: 2009-07-29
    Sponsor Name:Tarsa Therapeutics, Inc.
    Full Title: A Randomized, Double-Blind, Multiple Dose, Placebo-Controlled, Parallel Group, 48 Week, Study of Oral Recombinant Calcitonin (rsCT) Compared to Calcitonin Nasal Spray in Postmenopausal Osteoporotic...
    Medical condition: Postmenopausal Osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031285 Osteoporosis postmenopausal LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed) HU (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008013-19 Sponsor Protocol Number: MAMA2009 Start Date*: 2009-05-21
    Sponsor Name:Joan Xavier Fontdevila Font
    Full Title: Estudio aleatorizado para determinar la utilidad de la teicoplanina en la reducción de la colonización bacteriana de la superficie del expansor mamario en cirugía reconstructiva de mama
    Medical condition: Disminución de la colonización bacteriana en la cirugía reconstructiva de mama con la técnica en 2 tiempos (expansor-prótesis)
    Disease: Version SOC Term Classification Code Term Level
    9 10006188 Breast cancer female NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-008604-40 Sponsor Protocol Number: FE200486 CS31 Start Date*: 2009-04-09
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: A randomised, parallel-arm, open-label trial comparing degarelix with goserelin plus anti-androgen flare protection (bicalutamide), in terms of volume reduction of the prostate in patients with pro...
    Medical condition: Prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Completed) FI (Completed) DK (Completed) BE (Completed) PT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-003592-48 Sponsor Protocol Number: BUP/006/C Start Date*: 2008-11-25
    Sponsor Name:Novosis AG
    Full Title: A double-blind, multi-centre, reference-controlled, randomised Phase III study to compare the analgesic efficacy and tolerability of a buprenorphine transdermal system in two different application ...
    Medical condition: Patients with chronic, severe cancer pain requiring strong opioids and inadequately controlled with other analgesics.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005913-37 Sponsor Protocol Number: no sponsor Start Date*: 2009-03-09
    Sponsor Name:UMC Utrecht
    Full Title: Intratympanic gentamicin therapy for M Meniere: a comparison of two regimes
    Medical condition: Patients suffering of Menieres disease for at least 6 moths without sufficient relief of symptoms through medicinal therapy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027183 Meniere's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003801-15 Sponsor Protocol Number: 12011.202 Start Date*: Information not available in EudraCT
    Sponsor Name:PARIPharma GmbH
    Full Title: A phase II, randomised, double-blind, placebo controlled, parallel group, dose-finding clinical trial to investigate the efficacy and safety of 10 and 20 mg/day aerosolised liposomal ciclosporin A ...
    Medical condition: Bronchiolitis Obliterans Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049202 Bronchiolitis obliterans LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002857-18 Sponsor Protocol Number: H9P-MC-LNBI Start Date*: 2009-02-06
    Sponsor Name:Eli Lilly and Company
    Full Title: A Randomized, Double-Blind Comparison of LY2216684 and Placebo and Long Term Treatment with LY2216684 in Adult Patients with Major Depressive Disorder
    Medical condition: Patients with Major Depressive Disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision® (DSM-IV-TR; APA 2004),
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2008-007297-38 Sponsor Protocol Number: 1483/08 Start Date*: 2009-09-01
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effects of Atorvastatin on Number and Function of Pro-inflammatory CD4+CD28null T-cells and Defective Treg in Patients with Acute Coronary Syndromes
    Medical condition: acute coronary syndrome without ST segment elevation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011082 Coronary artery disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006208-52 Sponsor Protocol Number: IFN005 Start Date*: 2009-03-09
    Sponsor Name:Helix BioPharma Cooperation
    Full Title: Mono-centre, open-label study to investigate the multi-dose pharmacokinetics, efficacy and safety of Interferon alpha-2b Cream in women with a history of cytological diagnosed Pap IIID, with a con...
    Medical condition: cervical dysplasia (CIN I or CIN II; Pap IIID in the history, confirmed HPV+ status)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008263 Cervical dysplasia LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005053-38 Sponsor Protocol Number: VDF111687 Start Date*: 2009-06-08
    Sponsor Name:GlaxoSmithKline Research & Development Ltd.
    Full Title: An open-label study to investigate the pharmacodynamics of a repeat dose regimen of bevacizumab (10mg/kg q2w) and escalating repeat doses of pazopanib in renal cell carcinoma
    Medical condition: Metastatic Renal Cell Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-010384-16 Sponsor Protocol Number: C09-1 Start Date*: 2009-04-10
    Sponsor Name:GERCOR
    Full Title: A Phase III randomized trial investigating the duration of adjuvant therapy with the modified FOLFOX 6 regimen (3 versus 6 months) for patients with stage III colon cancer.
    Medical condition: Stage III colon cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009955 Colon cancer stage III LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005830-63 Sponsor Protocol Number: 0485-CL-0004 Start Date*: 2009-10-30
    Sponsor Name:Astellas Pharma Global Development, Inc. (APGD)
    Full Title: A Phase 2, Single-Arm Study to Evaluate the Safety and Pharmacokinetics of Alefacept in Adolescent Subjects with Moderate to Severe Psoriasis
    Medical condition: Moderate to severe chronic plaque psoriasis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037153 Psoriasis LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BG (Prematurely Ended) LV (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008852-18 Sponsor Protocol Number: PRAEMARKERAAT08 Start Date*: 2009-06-10
    Sponsor Name:Medizinische Universität Innsbruck Innere Medizin V
    Full Title: Profile of soluble and cellular biomarkers and of functional imaging during antiangiogenic therapies in cancer patients
    Medical condition: The present project is an academic clinical trial in which patient suffering from hepatocellular carcinoma, non-small cell lung cancer, renal cell cancer and colorectal cancer treated routinely wit...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-007315-32 Sponsor Protocol Number: ME/2008/3031 Start Date*: 2009-04-21
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: CIRCADIAN VARIATIONS IN CYTOKINES AND THE EFFECT OF TIMED RELEASE TABLET PREDNISONE IN POLYMYALGIA RHEUMATICA
    Medical condition: Polymyalgia Rheumatica
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036099 Polymyalgia rheumatica LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-007313-68 Sponsor Protocol Number: IG0801 Start Date*: 2009-01-07
    Sponsor Name:GRIFOLS ITALIA
    Full Title: A Prospective Randomized Pilot study to evaluate the effect of preoperative antithrombin supplementation on postoperative levels of antithrombin in patients undergoing cardiac surgery with cardiopu...
    Medical condition: Subjects undergoing elective cardiac surgery with Cardio Pulmonar Bypass (CPB) having baseline levels of ATIII activity equal to or higher than 60% and below 100% under all circumstances.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057461 Cardiac procedure complication LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011523-31 Sponsor Protocol Number: 09/H0720/64 Start Date*: 2009-06-23
    Sponsor Name:R & D, Cambridge University Hospitals
    Full Title: A study of the immune response to vaccination in MS patients treated with alemtuzumab
    Medical condition: The vaccinations are being used to investigate immunological memory following treatment of multiple sclerosis with the lympho-depleting humanised monoclonal antibody alemtuzumab.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063399 Relapsing-remitting multiple sclerosis PT
    9.1 10063400 Secondary progressive multiple sclerosis PT
    9.1 10046859 Vaccination LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011582-88 Sponsor Protocol Number: 41470956 Start Date*: 2009-05-28
    Sponsor Name:St James Hospital
    Full Title: The differential effects of donepezil and placebo on EEG/ ERP measures and fMRI in mild cognitive impairment and elderly controls
    Medical condition: Amnestic Mild cognitive Impairment (aMCI)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009846 Cognitive impairment LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-007815-99 Sponsor Protocol Number: AN07/8429 Start Date*: 2009-03-09
    Sponsor Name:Leeds Teaching Hospitals NHS Trust
    Full Title: The optimal dose of subcutaneous naloxone for the treatment of intrathecal opioid- induced pruritus following elective caesarean section delivery
    Medical condition: Pruritus secondary to intrathecal opioids
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049981 Drug-induced pruritus LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-009983-29 Sponsor Protocol Number: RLY5016–202 Start Date*: Information not available in EudraCT
    Sponsor Name:Relypsa, Inc.
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multiple-Dose Study to Evaluate the Effects of RLY5016 in Heart Failure Patients
    Medical condition: Hyperkalemia in heart failure patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020647 Hyperkalemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-009074-27 Sponsor Protocol Number: ACE-INIBITORE Start Date*: 2009-03-15
    Sponsor Name:PROF. ALFREDO CHETTA
    Full Title: Effect of an ACE inhibitor on the exercise capacity of COPD patients. A randomized double-blind placebo-controlled study
    Medical condition: PATIENTS AFFECTED BY COPD
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038738 SOC
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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