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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 853 of 2,220.
    EudraCT Number: 2007-000534-39 Sponsor Protocol Number: 2007-000534-39 Start Date*: 2007-06-01
    Sponsor Name:acep
    Full Title: etude comparative randomisee intra-individuelle de l'efficacite du traitement d'hidradenite suppuree ou maladie de verneuil par injections sous cutanee de toxine botulinique versus placebo
    Medical condition: L’hidradénite suppurée est une affection des glandes sudorales apocrines. Les glandes apocrines sont sous la dépendance des terminaisons nerveuses orthosympathiques . Le mécanisme d’action de la...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001170-92 Sponsor Protocol Number: 16787 Start Date*: 2007-09-12
    Sponsor Name:Erasmus MC
    Full Title: Dexamethasone for postoperative pain relief following tonsillectomy in children
    Medical condition: (Adeno)Tonsillectomy and Pain
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004089-15 Sponsor Protocol Number: AGO/2008/009 Start Date*: 2008-09-11
    Sponsor Name:University Hospital Ghent
    Full Title: The AZISAST Randomized Controlled Clinical Trial: Azithromycine as add-on therapy in Severe, Non-Eosinophilic Asthma
    Medical condition: Uncontrolled severe asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001005-16 Sponsor Protocol Number: CQAB149B2338 Start Date*: 2007-07-12
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 26 week treatment, randomized, multi center, double blind, double dummy, parallel-group study to assess the safety of indacaterol (300 and 600 µg o.d.) in patients with moderate to severe persist...
    Medical condition: moderate and severe persisitent asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) DE (Completed) FR (Completed) IT (Completed) SK (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-001383-70 Sponsor Protocol Number: CENA713DDE15 Start Date*: 2007-09-26
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A 24 week, multicenter, open evaluation of the clinical effectiveness of the once-daily 10 cm2 Exelon® patch formulation in patients with probable Alzheimer’s disease (MMSE10-26)
    Medical condition: probable Alzheimer's disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000420-40 Sponsor Protocol Number: 310442 Start Date*: 2007-08-08
    Sponsor Name:Bayer Schering Pharma Oy
    Full Title: Multi-center, open-label, randomized study to assess the safety and contraceptive efficacy of two doses (in vitro 12 µg/24 h and 16 µg/24 h) of the ultra low dose levonorgestrel contraceptive intra...
    Medical condition: Contraception
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010808 Contraception PT
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed) SE (Completed) HU (Completed) FR (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-002713-39 Sponsor Protocol Number: Dathyrca 1 Start Date*: 2007-10-23
    Sponsor Name:dept of endocrinology J 106, herlev Hosptial
    Full Title: Quality of life related to recombinant TSH treatment compared to no treatment related to iodine uptake, in patient with thyroid cancer. A double blinded, randomized crossover study. Dathyrca I
    Medical condition: in patients with thyroid cancer (follicular or papillary), injektion with recombinant TSH to increase s-TSH before iodine uptake to detect remaining cancer og recurrence of cancer in patients surg...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033701 Papillary thyroid cancer LLT
    9.1 10016935 Follicular thyroid cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001508-38 Sponsor Protocol Number: ST 200-DM-03-005 Start Date*: 2006-03-21
    Sponsor Name:SIGMA-TAU
    Full Title: Phase II Explorative Study of Acetyl-L-Carnitine (ST 200) for Vincristine-Induced Neurotoxicity in Patients With Acute Lymphoblastic Leukemia (ALL).
    Medical condition: Treatment of peripheral sensitive neuropathy vinca alkaloid chemotherapy -induced.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000846 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004673-26 Sponsor Protocol Number: PDX-012 Start Date*: 2008-01-31
    Sponsor Name:Allos Therapeutics Inc.,
    Full Title: Protocol PDX-012: A Randomized, Phase 2b, Multi-center Study of Pralatrexate Versus Erlotinib in Patients with Stage IIIB/IV Non-small Cell Lung Cancer After Failure of at Least 1 Prior Platinum-ba...
    Medical condition: Non Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066490 Progression of non small cell lung cancer LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-003126-15 Sponsor Protocol Number: DBCG 07-READ Start Date*: 2008-05-06
    Sponsor Name:DBCG
    Full Title: Randomized trial of sequential epirubicin and docetaxel against docetaxel in patients with early operable breast cancer.
    Medical condition: Women with operable breast cancer and increased risk of recurrence
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001916-22 Sponsor Protocol Number: Pressure Wire Study Start Date*: 2008-05-02
    Sponsor Name:Central Manchester and Manchester Children's Hospital University NHS Trust
    Full Title: Study to assess the optimum dose of intravenous adenosine in the assessment of fractional flow reserve
    Medical condition: To study the effects of higher dose adenosine on intermediate coronary lesions at coronary angiography which require pressure wire study.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002156-42 Sponsor Protocol Number: MB 1206/1770/04 Start Date*: 2007-11-22
    Sponsor Name:VALEAS
    Full Title: Effects of Treatment with Cefaclor in acute pharyngotonsillitis and activity on the immune system
    Medical condition: Acute pharyngotonsillitis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10062352 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001283-73 Sponsor Protocol Number: 109493 Start Date*: 2007-08-16
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A double-blind, randomized, placebo-controlled Phase III study to assess the efficacy of recMAGE-A3 + AS15 Antigen-Specific Cancer Immunotherapeutic as adjuvant therapy in patients with resectable ...
    Medical condition: Adjuvant therapy in patients with MAGE-A3-positive Non-Small Cell Lung Cancer (NSCLC) and who have had complete surgical resection
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029520 Non-small cell lung cancer stage IIIA PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029517 Non-small cell lung cancer stage I PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029518 Non-small cell lung cancer stage II PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) DE (Prematurely Ended) IE (Prematurely Ended) FI (Prematurely Ended) ES (Prematurely Ended) SI (Prematurely Ended) FR (Completed) SE (Prematurely Ended) GR (Prematurely Ended) IT (Prematurely Ended) LV (Prematurely Ended) AT (Completed) NL (Prematurely Ended) HU (Prematurely Ended) CZ (Prematurely Ended) EE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002472-34 Sponsor Protocol Number: EGF109462 Start Date*: 2007-08-06
    Sponsor Name:GlaxoSmithKline Research and Development Limited
    Full Title: A single-arm, two-stage Phase II study of Lapatinib and Pemetrexed in the second line treatment of advanced or metastatic Non-Small Cell Lung Cancer
    Medical condition: Patients with advanced or metatstatic Non-Small Cell Lung Cancer who have received one prior platinum containing chemotherapy regimen
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061873 Non-small cell lung cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006978-20 Sponsor Protocol Number: HBS407 Start Date*: 2007-11-21
    Sponsor Name:Talon Therapeutics , Inc.
    Full Title: A Phase 2 Study to Evaluate the Safety and Efficacy of Weekly Doses of Marqibo® (vincristine sulfate liposomes injection) in Adult Patients with Philadelphia Chromosome-negative Acute Lymphoblastic...
    Medical condition: Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000845 Acute lymphoblastic leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002553-23 Sponsor Protocol Number: H-00982-3256 Start Date*: 2007-10-10
    Sponsor Name:MEDA Pharma GmbH & Co. KG [...]
    1. MEDA Pharma GmbH & Co. KG
    2. MEDA Pharma GmbH & Co. KG
    3. MEDA Pharma GmbH & Co. KG
    4. MEDA Pharma GmbH & Co. KG
    Full Title: Clinical trial to assess the protective effect of the fixed drug combination of disodium cromoglycate plus reproterol in comparison to the single components and placebo in adults with exercise indu...
    Medical condition: Exercise induced asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015649 Exercise induced asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005256-33 Sponsor Protocol Number: 1182.107 Start Date*: 2007-09-14
    Sponsor Name:Boehringer Ingelheim España, S.A.
    Full Title: Ensayo clínico multicéntrico, aleatorizado y abierto para evaluar tres dosis de Tipranavir potenciado con dosis bajas de ritonavir (500mg/200mg una vez al día, 250mg/100 mg dos veces al día y 500 m...
    Medical condition: Los pacientes de este estudio deben ser varones y mujeres con edades comprendidas entre los 18 y los 65 años de edad infectados por VIH-1 y no tratados anteriormente con antirretrovirales.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020192 HIV-1 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-024315-14 Sponsor Protocol Number: 95609379 Start Date*: 2011-01-04
    Sponsor Name:Tekonivelsairaala Coxa
    Full Title: Paikallispuudutus polven tekonivelleikkauksen yhteydessä - vähentynyt opiaattien kulutus leikkauksen jälkeen ja nopeampi liikeharjoituksen aloitus - kaksoissokkotutkimus
    Medical condition: Polven nivelrikko.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10031174 Osteoarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002128-14 Sponsor Protocol Number: Local/2007/MD-01 Start Date*: 2009-02-11
    Sponsor Name:CHU de Nîmes
    Full Title: Anesthésie topique versus anesthésie épisclérale pour chirurgie de la cataracte
    Medical condition: Cataracte bilatérale
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001470-25 Sponsor Protocol Number: B4Z-SB-LYDV Start Date*: 2007-09-19
    Sponsor Name:Lilly Deutschland GmbH, Teichweg 3, 35396 Gießen
    Full Title: Randomisierte, doppelblinde Studie zum Vergleich neuropsychologischer Effekte von Atomoxetin gegen Placebo im Tagesverlauf bei Kindern mit Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung unter Anwen...
    Medical condition: Children (6-12 years) with ADHD (Attention-Deficit/Hyperactivity Disorder)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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