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Clinical trials for Placebo comparator

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44399   clinical trials with a EudraCT protocol, of which   7411   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,805 result(s) found for: Placebo comparator. Displaying page 9 of 91.
    EudraCT Number: 2015-002446-31 Sponsor Protocol Number: FMLD-HUNGRIA-28_FIII Start Date*: 2017-03-08
    Sponsor Name:LABORATORIOS FARMALIDER S.A.
    Full Title: Phase III clinical trial , multicenter , randomized , double-blind , crossover, active-controlled and placebo to evaluate the analgesic efficacy and safety of paracetamol / ibuprofen 500/200 mg com...
    Medical condition: MODERATE TO SEVERE PAIN FOLLOWING DYSMENORRHOEA
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000762-20 Sponsor Protocol Number: THR-4109-C-302 Start Date*: 2007-09-05
    Sponsor Name:Theracos, Inc.
    Full Title: A Phase II Randomized, Double-Blind, Double-Dummy, Parallel Group, Placebo Controlled Study of Galantamine + Sertraline, Galantamine or Sertraline in Obese Subjects
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029883 Obesity LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011785-28 Sponsor Protocol Number: CEN BIOTECH 150309 Start Date*: 2009-10-12
    Sponsor Name:SUBSTIPHARM DEVELOPPEMENT
    Full Title: Multicenter randomized, double blind, 3 parallel arms, controlled trial of the clinical efficacy of topical 'Diclofenac 1%, gel' (diclofenac diethylamine 1.16%) for the treatment of osteoarthritis ...
    Medical condition: Patient présentant une ostéorthrose douloureuse d'au moins un des genoux.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014242-28 Sponsor Protocol Number: IMIM-LEV-0901 Start Date*: Information not available in EudraCT
    Sponsor Name:CONSORCI MAR PARC DE SALUT BARCELONA
    Full Title: Estudio en fase IV, multicéntrico, doble ciego, aleatorizado y controlado con placebo para evaluar la eficacia y seguridad de la administración por vía intravenosa de dosis intermitentes de levosi...
    Medical condition: Pacientes con insuficiencia cardíaca crónica avanzada
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023536-16 Sponsor Protocol Number: ITN043AD Start Date*: 2011-02-25
    Sponsor Name:University of California, San Francisco, Immune Tolerance Network
    Full Title: A Randomised, Double-blind, Single-centre, Placebo controlled Study of Sublingual Immunotherapy and Subcutaneous Immunotherapy in Adults with Seasonal Allergic Rhinitis (ITN043AD)
    Medical condition: Grass-pollen induced rhinoconjunctivitis (hay fever).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005242-36 Sponsor Protocol Number: K40-3 Start Date*: 2006-12-13
    Sponsor Name:Moberg Derma AB
    Full Title: A multicenter, randomised, double-blind, placebo-controlled clinical study evaluating efficacy, safety and tolerability of topical K40 in 8 weeks treatment of adult patients with moderate to severe...
    Medical condition: Seborrhoeic Dermatitis of the scalp.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039794 Seborrhoeic dermatitis capitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005575-14 Sponsor Protocol Number: R-01270-A015 Start Date*: 2006-08-08
    Sponsor Name:Baxter R&D Europe S.C.R.L
    Full Title: A randomized, double-blind, placebo-controlled, single-dose, parallel-group comparison of the analgesic efficacy, safety and local tolerability of intravenous paracetamol 1% solution Bioren (test),...
    Medical condition: Post-surgical dental pain after removal of one or more impacted 3rd mandibular molar(s), associated with moderate to severe pain.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-003770-32 Sponsor Protocol Number: CLR_14_05 Start Date*: 2016-01-04
    Sponsor Name:Sun Pharma Advanced Research Company
    Full Title: A Randomized, Double-Blind, Four Treatment, Four period, Crossover Study, with Placebo, Tizanidine Immediate Release and Diphenhydramine to Study the Effect of Tizanidine Extended Release on Simula...
    Medical condition: healthy volunteers (acute musculoskeletal pain)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-002571-40 Sponsor Protocol Number: 231006 Start Date*: 2007-05-18
    Sponsor Name:NV Organon
    Full Title: A randomized, double-blind, active and placebo controlled trial to compare the relative analgesic efficacy and safety of a single intravenous dose of Org 28611 3.0 µg/kg, morphine sulfate 0.12 mg/...
    Medical condition: Postoperative analgesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036276 Postoperative analgesia LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-004883-20 Sponsor Protocol Number: SM1-JH-16 Start Date*: 2017-02-01
    Sponsor Name:Ole Mathiesen
    Full Title: Does perineural dexmedetomidine prolong the duration of an ulnar nerve block when controlling for possible systemic effects? - a randomized, blinded, placebo controlled, paired trial in healthy vo...
    Medical condition: Healthy volunteers (treatment intended to improve regional anesthesia for orthopedic surgery)
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-001250-24 Sponsor Protocol Number: 850 1016-1562 Start Date*: 2005-08-16
    Sponsor Name:APOGEPHA Arzneimittel GmbH
    Full Title: Proof-of-Concept Trial of NS-8 in 3 doses: Comparison of efficacy and tolerability in patients with overactive bladder.
    Medical condition: Subjects with overactive bladder syndrome with urinary urge.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019469-26 Sponsor Protocol Number: pRGF/016/09 Start Date*: 2010-07-29
    Sponsor Name:University of Aberdeen [...]
    1. University of Aberdeen
    2. NHS Grampian
    Full Title: Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre placebo controlled randomised trial of a calcium channel blocker(nifedipine)and an alpha b...
    Medical condition: Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: multicentre placebo controlled randomised trial of a calcium channel blocker(nifedipine) and an alpha bl...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002472-99 Sponsor Protocol Number: EVT302/3009 Start Date*: 2008-08-12
    Sponsor Name:Evotec Neurosciences GmbH
    Full Title: A phase II multicenter, randomised, double-blind, parallel group, placebo-controlled, study to evaluate the effectiveness of EVT 302 in smoking cessation, effect on its own and in combination with ...
    Medical condition: Male or female subjects who are chronic smokers, but motivated to quit smoking will be recruited.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001155-22 Sponsor Protocol Number: Lap2014NMB Start Date*: 2014-05-22
    Sponsor Name:Mona Ring Gätke
    Full Title: Muscle relaxation during open upper abdominal surgery -can the surgical conditions be optimized? (The laparotomy study)
    Medical condition: The aim of the study is to investigate if intense NMB improves surgical conditions during operation in patients scheduled for elective open upper abdominal surgery.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10023697 Laparotomy & drainage LLT
    17.0 100000004865 10051777 Staging laparotomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002524-27 Sponsor Protocol Number: 14-285 Start Date*: 2014-12-18
    Sponsor Name:University Medical Center Utrecht
    Full Title: A randomized, placebo-controlled, double blind, 4-period, cross-over trial, to study blood pressure lowering effects of losartan, Moxonidine and Low sodium diet in former pre-eclamptic women
    Medical condition: Post Partum Hypertension after preeclamptic pregnancy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001612-11 Sponsor Protocol Number: 3005032 Start Date*: 2018-01-11
    Sponsor Name:Region Hovedstaden
    Full Title: A COMPARISON OF DEXMEDETOMIDINE VS PLACEBO AFFECT ON SLEEP-QUALLITY IN MECHANICAL VENTILATED CRITICAL ILL PATIENTS
    Medical condition: Sleeping problems in mechanical ventilated critical ill patients in ICU
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10053319 Sleep study PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-001016-35 Sponsor Protocol Number: ZUH-UMPR-MICB Start Date*: 2019-05-29
    Sponsor Name:Associate Professor, Consultant Jens Børglum
    Full Title: The ultrasound-guided multiple-injection costotransverse block for mastectomy and primary reconstructive surgery. A double blind, randomised, placebo controlled trial.
    Medical condition: Postoperative pain following mastectomy and reconstructive surgery due to breast cancer.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10026881 Mastectomy radical LLT
    20.0 100000004865 10051042 Plastic surgery NOS LLT
    20.0 100000004864 10006188 Breast cancer female NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-003634-26 Sponsor Protocol Number: T151/2015 Start Date*: 2016-12-27
    Sponsor Name:Turku University Hospital
    Full Title: Antibiotic therapy vs. placebo in the treatment of acute uncomplicated appendicitis: a prospective randomized double-blind placebo-controlled trial
    Medical condition: Acute uncomplicated appendicitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10000677 Acute appendicitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-000006-32 Sponsor Protocol Number: IXR-203-30-204 Start Date*: 2005-06-13
    Sponsor Name:IVAX RESEARCH, INC.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PARALLEL GROUP, DOSE RANGING STUDY TO DETERMINE THE EFFICACY AND SAFETY OF AN INVESTIGATIONAL INTRANASAL CORTICOSTEROID COMPARED TO PLACEBO AND OPEN-LABEL FLUTICASONE PR...
    Medical condition: Perennial (persistant) Allergic Rhinitis
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003121-17 Sponsor Protocol Number: DU001 Start Date*: 2014-09-09
    Sponsor Name:D.A.S.T. BIOTECH PHARM Ε.Π.Ε.
    Full Title: Randomized, double-blind intervention study of efficacy and safety of the product Vioplex-T compared with placebo in patients with open sores (pressure ulcers).
    Medical condition: Pressured Ulcers in I & II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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