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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,347 result(s) found. Displaying page 989 of 2,218.
    «« First « Previous 985  986  987  988  989  990  991  992  993  Next» Last»»
    EudraCT Number: 2007-003189-16 Sponsor Protocol Number: CQMF149B2201 Start Date*: 2007-09-07
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, multi center, parallel group, double-blind, placebo and formoterol controlled 14 day dose ranging trial 4 doses of indacaterol delivered via Twisthaler®, in patients with COPD.
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) DE (Completed) HU (Completed) BE (Completed) FR (Completed) LT (Completed) GB (Completed) IT (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2005-002269-35 Sponsor Protocol Number: ML19115 Start Date*: 2005-07-05
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Phase II trial to evaluate the combination of FOLFOX6 + Bevacizumab in initially unresectable liver metastases from colorectal cancer
    Medical condition: METASTHATIC COLON-RECTUM AND KIDNEY CANCER
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055114 Colon cancer metastatic LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-003666-17 Sponsor Protocol Number: CS/2007/2608 Start Date*: 2007-11-09
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: The ATACAS Trial: Aspirin and Tranexamic Acid for Coronary Artery Surgery Trial
    Medical condition: Ischamic heart disease operated
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023024 Ischaemic heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002060-10 Sponsor Protocol Number: NN-PEN-003 Start Date*: 2007-06-29
    Sponsor Name:ikfe GmbH
    Full Title: Pharmacokinetics and Pharmacodynamics of subcutaneous applied insulin aspart administered with the FlexPen® insulin pen compared to inhaled insulin administered with the Exubera® device
    Medical condition: Type 1 and Type 2 Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012614 Diabetes mellitus NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009888-60 Sponsor Protocol Number: CLCQ908A2203 Start Date*: 2009-07-20
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 12-week multi-center, randomized, double-blind, placebo-controlled, parallel-group adaptive design study to evaluate the efficacy on blood glucose control and safety of five doses of LCQ908 (2, 5...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) IT (Completed) FR (Completed) BE (Completed) PL (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2007-001621-94 Sponsor Protocol Number: 2007-1805 Start Date*: 2007-08-11
    Sponsor Name:Lothian Health Board [...]
    1. Lothian Health Board
    2. University of Edinburgh
    Full Title: Pregabalin Bone Trial. A double-blind randomised controlled trial of pregabalin versus placebo in conjunction with palliative radiotherapy for malignant bone pain.
    Medical condition: The condition under investigation is cancer induced bone pain (CIBP). This is a major cause of morbidity in patients with cancer and unfortunately standard treatments (including radiotherapy) can b...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027452 Metastases to bone PT
    9.1 10033372 Pain and discomfort NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002058-41 Sponsor Protocol Number: DISFUNZIONE ERETTILE POST-RT Start Date*: 2007-07-12
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: EFFICACY EVALUATION OF TADALAFIL 20 MG ON DEMAND VS TADALAFIL 5 MG DAILY AS TREATMENT MODALITY FOR ERECTILE DYSFUNCTION FOLLOWING RADICAL RADIOTHERAPY IN PROSTATIC CANCER
    Medical condition: Erectile dysfunction following radiotherapy for prostatic cancer
    Disease: Version SOC Term Classification Code Term Level
    6.1 10060862 PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000903-14 Sponsor Protocol Number: CRO685 Start Date*: 2007-07-17
    Sponsor Name:Imperial College, London
    Full Title: Randomized Phase III Trial to evaluate the effect of statins on tumour biology in non-small cell lung cancer.
    Medical condition: Non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025050 Lung cancer non-small cell stage I LLT
    9.1 10025051 Lung cancer non-small cell stage II LLT
    9.1 10025052 Lung cancer non-small cell stage III LLT
    9.1 10025053 Lung cancer non-small cell stage IIIA LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002087-10 Sponsor Protocol Number: 1062.7 Start Date*: 2007-08-28
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: A randomised, double -blind, placebo-controlled, parallel group study to assess the efficacy and safety of 4 weeks treatment with sodium picosulphate [Dulcolax®, Laxoberal®] drops 10 mg administere...
    Medical condition: To compare the efficacy and safety of 4 weeks treatment with sodium picosulphate [Dulcolax®, Laxoberal®] drops to placebo in patients with functional constipation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010774 Constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002815-20 Sponsor Protocol Number: MET07 Start Date*: 2007-10-09
    Sponsor Name:Royal Surrey County Hospital
    Full Title: A Prospective Randomised Pilot Study of Metformin and Lifestyle Intervention in the Prevention of Metabolic Syndrome due to Androgen Deprivation Therapy in Prostate Cancer
    Medical condition: Patients with prostate cancer on androgen deprivation therapy (ADT). Randomisation between standard treatment with ADT only, and the additional use of metformin with dietary and exercise advice. Ai...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001186 Adenocarcinoma of prostate LLT
    9.1 10052066 Metabolic syndrome LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-002224-15 Sponsor Protocol Number: Start Date*: 2009-01-09
    Sponsor Name:Göteborgs Universitet
    Full Title: Individual GH dosing using 1st year GH responsiveness for prepubertal growth response in short GHD/ISS children
    Medical condition: GHD+ISS in prepubertal children born at term or prematurely, AGA or SGA GHD and SGA children (phase IV study) ISS children (phase III study)
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004099-38 Sponsor Protocol Number: CERCEFA 2 Start Date*: 2007-08-09
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: INDUCTION CHEMOTHERAPY FOLLOWED BY RADIOTHERAPY CONCOMITANT TO CETUXIMAB IN HEAD AND NECK SQUAMOUS CELL CARCINOMA: PHASE II STUDY
    Medical condition: head and neck squamous cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046311 Upper respiratory tract neoplasms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005442-37 Sponsor Protocol Number: CT200601 Start Date*: 2007-01-08
    Sponsor Name:University Medical Center St Radboud, department of neurology
    Full Title: PITUITARY DAMAGE AFTER TRAUMATIC BRAIN INJURY; Occurrence of growth hormone deficiency at long term follow-up and the beneficial effects of growth hormone substitution on cardiovascular performance...
    Medical condition: isolated growth hormone deficiency after traumatic brain injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011384-36 Sponsor Protocol Number: Studio Pregabalin Start Date*: 2009-09-22
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Randomized, controlled, trial, phase III, pregabalin vs placebo on postoperative morphine request after pectus escavatum surgery in children
    Medical condition: Acute pain management
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003339-22 Sponsor Protocol Number: V70P2E1 Start Date*: 2007-10-11
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l.
    Full Title: A Phase II, Observer-Blind, Parallel Groups, Single-Center, Extension Study to Evaluate the Immunogenicity and Safety Following a Single Intramuscular Dose of FLUAD or Vaxigrip Influenza Vaccines i...
    Medical condition: Influenza
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-001360-76 Sponsor Protocol Number: CLCZ696A2201 Start Date*: 2007-11-07
    Sponsor Name:NOVARTIS PHARMA SERVICES AG
    Full Title: A multi-center, randomized, double-blind, placebo and active controlled, parallel group, dose range study to evaluate the efficacy and safety of LCZ696 comparatively to valsartan, and to evaluate A...
    Medical condition: Essential Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DK (Completed) ES (Completed) NL (Completed) FI (Completed) FR (Completed) SE (Completed) LT (Completed) IT (Completed) SK (Completed) LV (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004533-15 Sponsor Protocol Number: PENTA Start Date*: Information not available in EudraCT
    Sponsor Name:Johannes Gutenberg-Universität Mainz, II. Med. Klinik (ausführende Stelle), Prof. Dr. T. Münzel
    Full Title: Effect of 8 weeks oral Pentaerithrityltetranitrate on endothelial dysfunction in patients with coronary artery disease: A prospective, randomized, double-blind, placebo-controlled, monocentric c...
    Medical condition: Women or men >35 and < 80 years of age with documented, clinically stable coronary artery disease with stable angina pectoris from the heart catheter register, II. Med. Klinik, Johannes Gutenberg-U...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049194 Stable angina pectoris LLT
    9.1 10011093 Coronary atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006480-23 Sponsor Protocol Number: 10,176 Start Date*: 2007-10-12
    Sponsor Name:University Hospitals of Leicester
    Full Title: Autologous Bone Marrow-Derived Cells for Cardioprotection During Heart Surgery
    Medical condition: Improvement of cardioprotection during elective coronary artery bypass graft surgery using the patients own bone marrow cells.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005078-28 Sponsor Protocol Number: AVA102677 Start Date*: 2007-11-28
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A 52-week open-label extension study of the long-term safety and efficacy of rosiglitazone extended-release (RSG XR) in subjects with mild-to-moderate Alzheimer's disease (REFLECT-5).
    Medical condition: Mild to Moderate Alzheimer's Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended) EE (Prematurely Ended) AT (Prematurely Ended) HU (Prematurely Ended) BG (Prematurely Ended) DE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006395-37 Sponsor Protocol Number: BRD/06/055 Start Date*: 2007-09-06
    Sponsor Name:Joint UCLH and UCL Biomedical Research Unit
    Full Title: A randomised, multi-centre feasibility trial in AL Amyloidosis, comparing CTD with SCT in patients with low risk of Treatment Related Mortality and CTD with Mel-Dex in patients in whom SCT would no...
    Medical condition: The medical condition to be investigated is systemic AL Amyloidosis, a disorder of protein folding in which normally soluble proteins are deposited as abnormal, insoluble fibrils that progressively...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002022 Amyloidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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