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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 993 of 2,219.
    EudraCT Number: 2007-004968-41 Sponsor Protocol Number: CPRC 2007-Dr BEAUCHESNE-TEMOFRAC Start Date*: 2008-02-06
    Sponsor Name:CHU DE NANCY - DIRECTION DE LA RECHERCHE CLINIQUE ET DE L'INNOVATION
    Full Title: Essai de phase II testant une association concomitante irradiation cérébrale ultra-fractionnée – témozolomide pour des glioblastomes multiformes inopérables de novo
    Medical condition: Glioblastomes multiformes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018337 Glioblastoma multiforme LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006475-36 Sponsor Protocol Number: RG_07-187 Start Date*: 2008-08-13
    Sponsor Name:University of Birmingham
    Full Title: Phase ll Study of the Adjunctive Use of Azacitidine in Patients Undergoing Reduced Intensity Allogeneic Transplantation for Acute Myeloid Leukaemia
    Medical condition: Patients who have Acute Myeloid Leukaemia (AML) will be recruited to this trial.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000880 Acute myeloid leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007630-19 Sponsor Protocol Number: msctendonrepair3 Start Date*: 2010-04-28
    Sponsor Name:Hospital Clinico San Carlos
    Full Title: TRATAMIENTO DE LAS LESIONES DEL MANGUITO ROTADOR MEDIANTE EL TRASPLANTE AUTÓLOGO DE CÉLULAS MADRE MESENQUIMALES DE ASPIRADOS DE MÉDULA ÓSEA. TREATMENT OF ROTATOR CUFF TEARS USING AUTOLOGOUS BONE M...
    Medical condition: TRATAMIENTO DE LAS LESIONES DEL MANGUITO ROTADOR MEDIANTE EL TRASPLANTE AUTÓLOGO DE CÉLULAS MADRE MESENQUIMALES DE ASPIRADOS DE MÉDULA ÓSEA
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003915-30 Sponsor Protocol Number: MT4VLU07/A-V7 Start Date*: 2008-05-15
    Sponsor Name:Gloucestershire Hospitals NHS Foundation Trust
    Full Title: The efficacy of maggots as a debridement agent for venous leg ulcers
    Medical condition: The purpose of the trial is to evaluate the effectiveness of BioFOAM maggots in achieving rapid debridement of chronic venous leg ulcers. Removal of slough and necrotic tissue from these wounds is ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000871-19 Sponsor Protocol Number: L00023 GE 409 Start Date*: 2008-04-10
    Sponsor Name:Pierre Fabre Médicament
    Full Title: Comparative study of efficacy and safety of Structum® and Chondrosulf® in patients with symptomatic osteoarthritis of the knee.A Multicenter, Randomized, Double-Blind, Double Placebo-Controlled, Pa...
    Medical condition: Symptomatic Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-001346-92 Sponsor Protocol Number: Nitroglycerin2 Start Date*: 2008-05-23
    Sponsor Name:No sponsor
    Full Title: Medical treatment with nitroglycerin for management of retained placenta - a multicentre trial
    Medical condition: Background: retained placenta occurs in 3% of all deliveries. The results from a pilot study indicate that medical treatment with a combination of oxytocin and the utero-relaxing agent nitroglycer...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000212-89 Sponsor Protocol Number: antagovo Start Date*: 2008-03-04
    Sponsor Name:Instituto Universitario IVI Valencia
    Full Title: Uso de antagonistas de la GnRH en la preparación endometrial de las receptoras de ovocitos.
    Medical condition: Comparar los resultados obtenidos con el empleo de antagonistas de la GnRH en la sincronización receptora de ovocitos–donante frente a los resultados obtenidos con el tradicional empleo de supresió...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005410-39 Sponsor Protocol Number: MEMTAC Start Date*: 2008-06-11
    Sponsor Name:Grupo Catalán de Estudio de enfermedades glomerulares. Sociedad Catalana de nefrología.
    Full Title: “Estudio piloto aleatorizado comparativo de tacrolimus vs ciclofosfamida-prednisona en la nefropatía membranosa idiopática”
    Medical condition: La nefropatía membranosa idiopática (NMI) es una enfermedad caracterizada histopatológicamente por un engrosamiento uniforme de la pared de los capilares glomerulares, debido al depósito de complej...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027170 Membranous nephropathy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000325-20 Sponsor Protocol Number: 2007.494/37 Start Date*: 2008-05-14
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Rééducation de l’héminégligence par adaptation prismatique. Intérêt de l’association d’un traitement par Méthilphénidate (RITALINE®). Etude des mécanismes de plasticité cérébrale impliqués.
    Medical condition: neurologic neglect syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029289 Neurologic neglect syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002667-28 Sponsor Protocol Number: 0974-031 Start Date*: 2008-05-29
    Sponsor Name:Merck Sharp & Dohme (Sweden) AB
    Full Title: A Multicenter, Double-Blind, Placebo-Controlled, Parallel Group Multiple Attacks Study to Compare the Efficacy and Safety of Oral MK-0974 With Placebo for the Acute Treatment of Migraine With or Wi...
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027599 Migraine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) CZ (Completed) ES (Completed) AT (Completed) DK (Completed) FR (Completed) NL (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005230-37 Sponsor Protocol Number: HPV01/01 Start Date*: 2008-04-02
    Sponsor Name:Leiden University Medical Center
    Full Title: Randomised Controlled Study on the Effects of Imiquimod, a TLR 7 Activating Agent, on the HPV16-Specific Immune Response Following HPV16 E6/E7 Synthetic Long Peptides Vaccination in Women with HPV1...
    Medical condition: Adult female patients, with histological evidence of Vulvar intraepithelial neoplasia (VIN) grade III lesions of the squamous cell type, positive for HPV (Human Papilloma Virus)16.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056574 Vulval intraepithelial neoplasia LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2007-007625-43 Sponsor Protocol Number: 2007PCT018 Start Date*: 2008-04-18
    Sponsor Name:Birmingham Children’s Hospital NHS Foundation Trust
    Full Title: A randomised controlled trial of two analgesic techniques for the control of pain and post-operative nausea and vomiting in paediatric day-case tonsillectomy.
    Medical condition: Tonsillectomy is one of the most common surgical procedures in children and is usually associated with moderate to severe pain which is problematic to treat because of side effects associated with ...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-007587-21 Sponsor Protocol Number: CLL10 Start Date*: 2008-09-05
    Sponsor Name:University of Cologne
    Full Title: Phase III trial of combined immunochemotherapy with Fludarabine, Cyclophosphamide and Rituximab (FCR) versus Bendamustine and Rituximab (BR) in patients with previously untreated chronic lymphocyti...
    Medical condition: patients (age 18 years or older) with chronic lymphocytic leukemia: Stage Binet C or stage Binet B and A requiring treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009310 CLL LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) DK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-001793-87 Sponsor Protocol Number: M/37779/23 Start Date*: 2007-07-31
    Sponsor Name:Laboratorios Almirall, S.A.
    Full Title: A Multicenter, Randomized, Double-Blind, Parallel-Group, Vehicle and Active Controlled Trial, to Assess the Efficacy and Safety of LAS37779 Cream for the Treatment of Chronic Plaque Psoriasis
    Medical condition: Male and female patients, 18 to 70 years of age, with a diagnosis of chronic plaque psoriasis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037153 Psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004833-40 Sponsor Protocol Number: EFC10518 Start Date*: 2008-05-14
    Sponsor Name:sanofi-aventis recherche & developpement
    Full Title: A randomized, double blind, placebo controlled study evaluating the glycemic effect of rimonabant added to metformin in patients with type 2 diabetes insufficiently controlled with metformin monoth...
    Medical condition: Type 2 Diabetes patients insufficiently controlled with metformin monotherapy
    Disease: Version SOC Term Classification Code Term Level
    10.1 10067585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Prematurely Ended) SK (Completed)
    Trial results: View results
    EudraCT Number: 2008-001001-41 Sponsor Protocol Number: PR002-CLN-pro008 Start Date*: 2008-06-02
    Sponsor Name:Protherics Medicines Development Ltd, a BTG plc company
    Full Title: A Randomized, Double Blind, Placebo Controlled Study of the Efficacy and Safety of Angiotensin Therapeutic Vaccine (ATV) in Patients With Mild to Moderate Hypertension
    Medical condition: Men and women, 35-70 years old with mild to moderate Hypertension as classified by the British Hypertension Society (BHS) Guidelines - BHS-IV based on the following crietia of sitting blood pressur...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020772 Hypertension LLT
    9.1 10020772 Hypertension PT
    9.1 10042957 Systolic hypertension PT
    9.1 10012758 Diastolic hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000207-15 Sponsor Protocol Number: 1184.24 Start Date*: 2008-02-26
    Sponsor Name:Boehringer Ingelheim bv
    Full Title: A randomised, open-label, 4-way crossover study to characterize the pharmacokinetics, safety and efficacy of tiotropium and salmeterol after inhalation of Tiotropium/Salmeterol (7.5 µg/25 µg) Inhal...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000066-22 Sponsor Protocol Number: BAY 43-9006 Start Date*: 2008-04-30
    Sponsor Name:Christie Hospital NHS Foundation Trust
    Full Title: A Phase 2 study of Sorafenib (BAY 43-9006) in patients with advanced salivary Adenoid Cystic Carcinoma
    Medical condition: advanced salivary adenoid cystic carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053231 Adenoid cystic carcinoma PT
    9.1 10051975 Salivary gland carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001037-98 Sponsor Protocol Number: 2203/07 Start Date*: 2008-03-10
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: The minimum effect-site concentration of propofol that is able to prevent the responses to stimuli used to evoke cranial reflexes
    Medical condition: patients undergoing general anaesthesia for elective surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001462-81 Sponsor Protocol Number: FARM7KP2PX Start Date*: 2008-10-27
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: Effects of Losartan versus Nebivolol versus the association of both on the progression of aortic root dilation in Marfan Syndrome (MFS) with FBN1 gene mutations
    Medical condition: Marfan Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10026829 Marfan's syndrome LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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