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Clinical trials for AMC

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44294   clinical trials with a EudraCT protocol, of which   7351   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    91 result(s) found for: AMC. Displaying page 1 of 5.
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    EudraCT Number: 2005-000974-29 Sponsor Protocol Number: TH0501 Start Date*: 2005-04-01
    Sponsor Name:Boots Healthcare International Limited
    Full Title: An open label, oral bioavailability study to determine the levels of Amylmetacresol BP (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) in the saliva of healthy volunteers after a single oral dose of S...
    Medical condition: AMC and DCBA are indicated for the symptomatic relief of mouth and throat infections.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002269-14 Sponsor Protocol Number: NL80263.018.21 Start Date*: 2022-08-11
    Sponsor Name:AMC, Cardiovascular Sciences
    Full Title: Dotatate to locate coronary plaques at high-risk of myocardial infarction
    Medical condition: Inflammatory atherosclerosis of the coronary arteries.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003739-40 Sponsor Protocol Number: 59153 Start Date*: 2017-03-06
    Sponsor Name:AMC Amsterdam
    Full Title: The effect of Iberogast on heartburn in patients with dyspepsia
    Medical condition: Dyspepsia (according to the Rome III criteria) with heartburn. Upper gastro-intestinal causes of the complaints excluded via gastroscopy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-000404-35 Sponsor Protocol Number: 80519 Start Date*: 2022-07-26
    Sponsor Name:AMC, Cardiovascular Sciences
    Full Title: Does the hematopoietic stem cell govern residual inflammatory cardiovascular risk in type 2 diabetes?
    Medical condition: Inflammation in patients with type 2 diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001240-21 Sponsor Protocol Number: 69024 Start Date*: 2019-07-03
    Sponsor Name:Amsterdam UMC, location AMC
    Full Title: Exposure to orally administered antibiotics during the initial phase of infection in non-critically ill, febrile patients
    Medical condition: Exposure to oral antibiotics will be investigated in infectious patients when they are febrile compared to when they are afebrile. The infection itself is unspecified.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000543-27 Sponsor Protocol Number: 19852012 Start Date*: 2012-04-23
    Sponsor Name:AMC
    Full Title: A Proof of Concept Study to Determine the Local Delivery and Efficacy of Intravenously Injected PEG-Liposomal Prednisolone Sodium Phosphate (Nanocort®) in Atherosclerotic Tissue in Subjects with Pe...
    Medical condition: Vessel wall inflammation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000449-15 Sponsor Protocol Number: DIONYSIUS Start Date*: 2020-12-11
    Sponsor Name:Amsterdam University Medical Centers, location AMC
    Full Title: Does Increasing Oxygen Nurture Your Symptomatic Ischemic Ulcer Sufficiently?
    Medical condition: Ischemic diabetic foot ulcers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002860-19 Sponsor Protocol Number: 2012 Start Date*: 2014-01-07
    Sponsor Name:AMC
    Full Title: The risk of cardiovascular disease in Ankylosing Spondylitis; A Single Center Cross-Sectional Study Evaluating The Association Between Inflammation In Ankylosing Spondylitis And Vascular Inflammati...
    Medical condition: Ankylosing Spondylitis Atherosclerotic cardiovascular disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003168-28 Sponsor Protocol Number: 77458 Start Date*: 2022-06-28
    Sponsor Name:Academic Medical Center (AMC), department of Internal Medicine
    Full Title: Impact of Triglyceride-Lowering on Inflammatory Activity in Patients with Hypertriglyceridemia
    Medical condition: - Hypertriglyceridemia - Inflammation - Lipoproteins
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-004078-53 Sponsor Protocol Number: 83403 Start Date*: 2023-08-22
    Sponsor Name:Academic Medical Center (AMC), department of Internal Medicine
    Full Title: Specifying the anti-inflammatory effects of ziltivekimab with diverse imaging modalities and in-depth cellular phenotyping
    Medical condition: - Plaque characteristics - Systemic inflammation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002667-42 Sponsor Protocol Number: ABR53999 Start Date*: 2015-09-09
    Sponsor Name:AMC
    Full Title: Sedation with propofol TCI during ERCP: Is the combination with esketamine more effective and safer than with alfentanil (SPEKA): A randomized controlled multicentre trial
    Medical condition: Patients undergoing ERCPs under propofol sedation combined with ketamine or alfentanil given by trained anesthesia nurse.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004995-17 Sponsor Protocol Number: NL7507301820 Start Date*: 2021-03-11
    Sponsor Name:AMsterdam UMC-AMC
    Full Title: Low dose iron chelation as TReatment of Oxidative stress in Sickle cell disease; TROS study
    Medical condition: Sickle cell disease (an hereditary hemoglobinopathy)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002179-12 Sponsor Protocol Number: PRILODE50-FUSION Start Date*: 2022-09-16
    Sponsor Name:Matilde Zaballos
    Full Title: Determination of the effective dose 50 of intrathecal hyperbaric prilocaine required for the transrectal ultrasound guidance fusion-targeted prostate biopsy in ambulatory surgery
    Medical condition: anaesthesia for prostate fusion biopsy in outpatient surgery
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004848 10004825 Biopsy of prostate LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-005021-79 Sponsor Protocol Number: 72541 Start Date*: 2020-03-10
    Sponsor Name:Amsterdam UMC - location Academic Medical Centre (AMC)
    Full Title: Revised dosing recommendations of ciprofloxacin for patients with impaired renal function: a bioequivalence study.
    Medical condition: Ciprofloxacin exposure in patients treated for a bacterial infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002864-30 Sponsor Protocol Number: NL73019.018.20 Start Date*: 2020-07-29
    Sponsor Name:Amsterdam UMC, location AMC
    Full Title: Sulodexide for chronic heart failure: a proof of concept, randomized, placebo-controlled study
    Medical condition: Chronic heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-005059-67 Sponsor Protocol Number: TH0809 Start Date*: 2008-11-04
    Sponsor Name:Reckitt Benckiser Healthcare UK Ltd
    Full Title: A multi-centre, randomised, double blind, placebo-controlled, parallel group, single dose, pilot study of the efficacy of 0.6 mg Amylmetacresol BP (AMC) and 1.2mg 2,4-Dichlorobenzyl alcohol (DCBA) ...
    Medical condition: Sore throat
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041367 Sore throat LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003594-17 Sponsor Protocol Number: NL59077.018.16 Start Date*: 2018-05-28
    Sponsor Name:AMC
    Full Title: Effects of a single denosumab injection on reduction of total contact cast treatment and consolidation of bonefractures caused by acute Charcotfoot in patients with diabetes mellitus (CHARCOT st...
    Medical condition: charcot foot
    Disease: Version SOC Term Classification Code Term Level
    20.1 10027433 - Metabolism and nutrition disorders 10012607 Diabetes mellitus inadequate control PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003594-95 Sponsor Protocol Number: MTXSB2018 Start Date*: 2019-04-30
    Sponsor Name:Amsterdam UMC location AMC
    Full Title: Methotrexate to suppress immunogenicity to anti-tumor necrosis factor therapy in IBD patients with loss of response
    Medical condition: Inflammatory bowel disease: Crohn's disease and Ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    20.1 10017947 - Gastrointestinal disorders 10045365 Ulcerative colitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004206-19 Sponsor Protocol Number: ABR36861 Start Date*: 2012-01-12
    Sponsor Name:AMC
    Full Title: Patient and Endoscopist Satisfaction with DEXmedetomidine versus Propofol/Alfentanil sedation during oesophagus interventions (PESDEX).
    Medical condition: Patients undergoing therapeutically esophageal interventions under sedation (dexmedetomidine or propofol/alfentanil) given by trained anesthesia nurse.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-003245-29 Sponsor Protocol Number: SA652013 Start Date*: 2016-12-19
    Sponsor Name:Amsterdam AMC, locatie AMC
    Full Title: Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after Roux-en-Y gastric bypass and Sleeve Gastrectomy
    Medical condition: Prevention of symptomatic gallstone disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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