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Clinical trials for Acetylcholine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    57 result(s) found for: Acetylcholine. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2006-004374-27 Sponsor Protocol Number: ProPATIent Start Date*: 2006-10-12
    Sponsor Name:Philipps-University
    Full Title: Prospective, randomized, doubleblind, placebo-controlled trial on changes in acetylcholine receptor antibody titres in autoimmune myasthenia gravis after influenza vaccination (ProPATIent)
    Medical condition: Generalized Myasthenia gravis with positive antibodies against Acetylcholine-receptors (ICD10GM2006 G70.0)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004979-19 Sponsor Protocol Number: EK Reg.-Nr. 040-2007 Start Date*: 2009-01-08
    Sponsor Name:University of Leipzig
    Full Title: In-vivo assessment of nicotinic acetylcholine receptor binding in neurodegenerative diseases using the radioligand 2-[18F]FA-85380 and positron emission tomography (PET)
    Medical condition: To test a diagnostic imaging tool for specifically assessing the nicotinic acetylcholine receptor in vivo in patients with neurodegenerative diseases
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-003518-41 Sponsor Protocol Number: 2018-4765 Start Date*: 2019-10-03
    Sponsor Name:Radboudumc
    Full Title: Efficacy of Diltiazem to improve coronary microvascular dysfunction: A randomized clinical trial
    Medical condition: Coronary Microvascular Dysfunction (CMD). In CMD, ischemia is caused by impaired endothelial and/or non-endothelial coronary vasoreactivity resulting in the coronary microvasculature not dilating p...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003116-22 Sponsor Protocol Number: RBK091 Start Date*: 2006-12-21
    Sponsor Name:Prof. Sechtem, Department of Cardiology, Robert Bosch Hospital
    Full Title: Application of Sildenafil in patients with documented coronary vasospasm in order to explore the pathophysiology of coronary vasospasm and the therapeutic effects of Sildenafil in patients sufferin...
    Medical condition: Coronary vasospasm is an abrupt severe vasoconstriction of coronary arteries leading to myocardial ischemia and angina pectoris. The reason for the occurrence of coronary spasm and the cellular mec...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003775-21 Sponsor Protocol Number: ALH2 Start Date*: 2008-08-14
    Sponsor Name:Salford Royal Hospitals NHS Trust [...]
    1. Salford Royal Hospitals NHS Trust
    2. University of Manchester
    Full Title: Effects of atorvastatin on microcirculatory endothelial function in patients with systemic sclerosis
    Medical condition: Systemic sclerosis (also termed 'scleroderma')
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-002268-42 Sponsor Protocol Number: 205767 Start Date*: 2018-03-29
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomized, repeat dose, open label, parallel group, multi-center study to evaluate the effect of daprodustat compared to darbepoetin alfa on forearm blood flow in participants with anemia of chr...
    Medical condition: anemia associated with chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-000097-35 Sponsor Protocol Number: CCFZ533X2204 Start Date*: 2015-09-02
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-center, randomized, double-blind, placebo-controlled, parallel group study to preliminarily evaluate the safety, tolerability, pharmacokinetics and efficacy of CFZ533 in patients with moder...
    Medical condition: Acquired myasthenia gravis (MG) is an autoimmune disease that leads to fluctuating muscle weakness and fatigue. In the most common cases, muscle weakness is caused by circulating antibodies that bi...
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10028417 Myasthenia gravis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-005433-39 Sponsor Protocol Number: ADFNLE Start Date*: 2012-03-22
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA DI CAGLIARI
    Full Title: PHASE II OPEN STUDY ABOUT THE EFFECTIVENESS OF FENOFIBRATE AS ADD ON THERAPY FOR DRUG RESISTANT NOCTURNAL FRONTAL LOBE EPILEPSY (FNLE) .
    Medical condition: Drug resistant nocturnal frontal lobe epilepsy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10049424 Frontal lobe epilepsy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005164-27 Sponsor Protocol Number: 260981 Start Date*: 2008-02-22
    Sponsor Name:research office urology VUmc
    Full Title: Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/ Interstitial Cystitis
    Medical condition: Interstitial Cystitis (IC) is a syndrome characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The patho-physiology remains largely unclear. No univ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016446-50 Sponsor Protocol Number: - Start Date*: 2010-04-19
    Sponsor Name:Maastricht University - CAPHRI School for Public Health and Primary Care
    Full Title: Helping more smokers to quit by combining varenicline with counselling for smoking cessation. The COVACO randomized controlled trial.
    Medical condition: Smoking: Subjects must be daily smokers
    Disease: Version SOC Term Classification Code Term Level
    12.0 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002243-27 Sponsor Protocol Number: 305/2004 Start Date*: 2004-08-14
    Sponsor Name:Clinical Pharmacology
    Full Title: Vascular effects of peroxisome proliferator–activated receptor gamma stimulation with rosiglitazone during exogenousely elevated free fatty acid concentrations in healthy volunteers
    Medical condition: healthy
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002599-15 Sponsor Protocol Number: 21709298 Start Date*: 2017-11-07
    Sponsor Name:Aarhus University
    Full Title: Effect of pyridostigmine (Mestinon®) on muscle strength in Myasthenia Gravis.
    Medical condition: Myasthenia Gravis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10071942 Myasthenia gravis and related conditions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003138-26 Sponsor Protocol Number: 58746 Start Date*: 2016-10-04
    Sponsor Name:LUMC
    Full Title: Influenza vaccination in patients with Myasthenia Gravis
    Medical condition: Myasthenia gravis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002132-25 Sponsor Protocol Number: ARGX-113-1704 Start Date*: 2019-04-30
    Sponsor Name:argenx BVBA
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Trial to Evaluate the Efficacy, Safety and Tolerability of ARGX-113 in Patients with Myasthenia Gravis Having Generalized Muscle ...
    Medical condition: Myasthenia Gravis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10028417 Myasthenia gravis PT
    20.0 10029205 - Nervous system disorders 10028423 Myasthenia gravis-like syndrome LLT
    20.0 100000004859 10071942 Myasthenia gravis and related conditions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) FR (Completed) CZ (Completed) DE (Completed) HU (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016053-18 Sponsor Protocol Number: VILD1 Start Date*: 2009-12-09
    Sponsor Name:UMC St Radboud
    Full Title: The effect of vildagliptin on endothelium-dependent vasodilatation. A double blind, cross-over study in type 2 diabetes.
    Medical condition: The effect of vildagliptin on endothelial dysfunction in type 2 diabetes, assessed by measuring endothelium-dependent vasodilatation
    Disease: Version SOC Term Classification Code Term Level
    12.0 10048554 Endothelial dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-000771-17 Sponsor Protocol Number: DM2ATV Start Date*: 2008-05-05
    Sponsor Name:RUNMC
    Full Title: Hyperbilirubinemia, the favourable side effect of atazanavir? Influence of atazanavir treatment on endothelial dysfunction, vascular inflammation and heme oxygenase activity in type 2 diabetes mell...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053246 Type II diabetes peripheral angiopathy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-014643-36 Sponsor Protocol Number: MeBe/08/NEB-MICR/001 Start Date*: 2010-04-23
    Sponsor Name:MENARINI Benelux NV/SA
    Full Title: Effects Of The Administration Of Nebivolol Versus Carvedilol On Microcirculatory Endothelial Function, Arterial Stiffness And Wave Reflection In Healthy Volunteers” (NeCaMic-study)
    Medical condition: Microcirculatory Endothelial Function, Arterial Stiffness And Wave Reflection
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-003958-94 Sponsor Protocol Number: CVAH631BDE06 Start Date*: 2005-12-02
    Sponsor Name:Novartis Phama GmbH
    Full Title: A randomized, open-label, multicenter, cross-over trial to evaluate the efficacy of a 20 week treatment of Valsartan 320 mg (Diovan) versus Atenolol 100 mg in combination with Hydrochlorothiazide o...
    Medical condition: Essential mild-to-moderate hypertension
    Disease: Version SOC Term Classification Code Term Level
    M15 10020772 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000188-25 Sponsor Protocol Number: LoveMi Start Date*: 2013-10-23
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Lormetazepam versus Midazolam used as sedatives for critically ill patients.
    Medical condition: Sedation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000949-14 Sponsor Protocol Number: VIB0551.P3.S1 Start Date*: 2020-11-16
    Sponsor Name:Viela Bio, Inc.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, MULTICENTER, PLACEBO-CONTROLLED PHASE 3 STUDY WITH OPEN-LABEL PERIOD TO EVALUATE THE EFFICACY AND SAFETY OF INEBILIZUMAB IN ADULTS WITH MYASTHENIA GRAVIS
    Medical condition: Myasthenia Gravis which is either due to acetylcholine receptor antibodies (AChR) or muscle specific kinase antibodies (MuSK).
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10028417 Myasthenia gravis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) DK (Prematurely Ended) DE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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