Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Acute heart failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    511 result(s) found for: Acute heart failure. Displaying page 1 of 26.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-004485-14 Sponsor Protocol Number: 20060810 Start Date*: 2007-01-18
    Sponsor Name:Aarhus University Hospital, Skejby sygehus
    Full Title: Metabolic Modulation as treatment of acute heart failure in patients
    Medical condition: acute decompensated heart failure
    Disease: Version SOC Term Classification Code Term Level
    8.1 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002688-31 Sponsor Protocol Number: ICOR-2022-04-LEVOMEMS Start Date*: 2023-01-25
    Sponsor Name:Germans Trias i Pujol Health Research Institute
    Full Title: LEVO-MEMS: COMPARISION OF THE HAEMODINAMIC PROFILE OF DOBUTAMIN AND LEVOSIMENDAN IN THE CURRENT THERAPEUTICAL CONTEXT
    Medical condition: Heart failure patients with depressed left ventricular ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    20.0 100000004849 10010684 Congestive heart failure LLT
    20.0 100000004849 10019284 Heart failure, congestive LLT
    20.0 100000004849 10024106 Left heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001513-25 Sponsor Protocol Number: 50268-20150921 Start Date*: 2016-05-12
    Sponsor Name:Aarhus University Hospital
    Full Title: Metformin in patients with chronic and acute heart failure: Pharmacokinetics and polymorphisms in genes encoding membrane metformin transporter proteins
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10000803 Acute heart failure LLT
    19.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-000833-35 Sponsor Protocol Number: CRLX030A2201 Start Date*: 2011-10-24
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, phase II, double blind, randomized, parallel group, placebo-controlled study to evaluate the hemodynamic responses to intravenous RLX030 infusion in subjects with acute heart failure.
    Medical condition: Acute Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) IT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-021263-33 Sponsor Protocol Number: 3001101 Start Date*: 2011-05-24
    Sponsor Name:Sykehuset i Vestfold HF
    Full Title: PERIOPERATIVE LEVOSIMENDAN INFUSION IN PATIENTS WITH HEART FAILURE UNDERGOING NON-CARDIAC SURGERY: A PROSPECTIVE, RANDOMISED, PLACEBO-CONTROLLED, DOUBLE-BLIND, MULTICENTER STUDY
    Medical condition: Patients with serious cardiac failure scheduled for non-cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10006387 Broken hip LLT
    14.1 10007541 - Cardiac disorders 10007559 Cardiac failure congestive PT
    14.1 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    14.1 10007541 - Cardiac disorders 10066498 Cardiac failure chronic aggravated LLT
    14.1 10007541 - Cardiac disorders 10007558 Cardiac failure chronic PT
    14.1 10007541 - Cardiac disorders 10024102 Left cardiac failure LLT
    14.1 10007541 - Cardiac disorders 10007561 Cardiac failure left LLT
    14.1 10007541 - Cardiac disorders 10007555 Cardiac failure (NOS) LLT
    14.1 10007541 - Cardiac disorders 10007564 Cardiac failure, congestive LLT
    14.1 10007541 - Cardiac disorders 10007562 Cardiac failure NOS LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10020100 Hip fracture PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002367-34 Sponsor Protocol Number: 29052016 Start Date*: 2016-09-30
    Sponsor Name:Hjertemedicinsk klinik, Rigshospitalet
    Full Title: Beta 3 agonist treatment in heart failure (BEAT-HF II)
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-002236-92 Sponsor Protocol Number: 9151 Start Date*: 2011-08-11
    Sponsor Name:Maatschap cardiologie Isala klinieken Zwolle
    Full Title: Dopamine on top of standard treatment for patients with exacerbation of Heart Failure, at home situation
    Medical condition: exacerbation of Heart Failure treated at home
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10000803 Acute heart failure LLT
    13.1 10007541 - Cardiac disorders 10019284 Heart failure, congestive LLT
    13.1 10007541 - Cardiac disorders 10024106 Left heart failure LLT
    13.1 10007541 - Cardiac disorders 10064082 Heart failure NYHA class IV LLT
    13.1 10007541 - Cardiac disorders 10008908 Chronic heart failure LLT
    13.1 10007541 - Cardiac disorders 10064653 Acute decompensated heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001637-10 Sponsor Protocol Number: 12008 Start Date*: 2008-09-18
    Sponsor Name:HUCH, Division of Cardiology
    Full Title: Acute heart failure in acute coronary syndrome: Double blind comparison of levosimendan and placebo
    Medical condition: Acute coronary syndrome treated with percutaneous coronary intervention (PCI) Patients suffering from acute heart failure after the procedure will be randomised to the study
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001679-22 Sponsor Protocol Number: EMPA-UMCG-1 Start Date*: 2017-10-27
    Sponsor Name:Univeristy Medical Center Groningen
    Full Title: Randomized, double blind, placebo controlled, multicenter pilot study on the effects of empagliflozin on clinical outcomes in patients with acute decompensated heart failure
    Medical condition: Acute (decompensated) heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019280 Heart failures HLGT
    20.0 100000004908 10019283 Heart failure signs and symptoms HLT
    20.0 100000011689 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010236-18 Sponsor Protocol Number: CSPP100A2368 Start Date*: 2009-05-28
    Sponsor Name:Novartis Farmacéutica S.A.
    Full Title: Estudio multicéntrico, aleatorizado, doble ciego, de grupos paralelos, controlado con placebo para evaluar la eficacia y seguridad a 6 meses de la terapia de aliskiren, además de la terapia estánda...
    Medical condition: Insuficiencia Cardiaca aguda descompensada
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) CZ (Completed) BE (Completed) IT (Completed) SK (Completed) PL (Completed) HU (Completed) SE (Completed) FI (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2015-003266-87 Sponsor Protocol Number: CLCZ696B2401 Start Date*: 2016-03-02
    Sponsor Name:Novartis Pharma services AG
    Full Title: A multicenter, randomized, open label, parallel group study comparing pre-discharge and posT-discharge tReatment initiation with LCZ696 in heArt failure patieNtS with reduced ejectIon-fracTion hosp...
    Medical condition: Heart Failure with reduced ejection fraction (HF-rEF) stabilized after hospitalization due to acute decompensated heart failure episode.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) SK (Completed) PT (Completed) SE (Completed) ES (Completed) CZ (Completed) FR (Completed) BE (Completed) PL (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-004186-40 Sponsor Protocol Number: CV019-010 Start Date*: 2020-06-18
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Randomized, Double-Blinded, Placebo-Controlled, Study to Evaluate the Safety and Tolerability of BMS-986259 in Stabilized Patients Hospitalized for Acute Decompensated Heart Failure
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NL (Completed) GR (Completed) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001498-25 Sponsor Protocol Number: CRLX030A2301 Start Date*: 2013-09-09
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomized, double-blind, placebo-controlled phase IIIb study to evaluate the efficacy, safety and tolerability of Serelaxin when added to standard therapy in acute heart failure pa...
    Medical condition: Acute heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) BE (Completed) SE (Completed) IE (Completed) BG (Completed) HU (Completed) PT (Completed) LT (Prematurely Ended) IT (Completed) CZ (Completed) AT (Completed) EE (Completed) DK (Completed) ES (Completed) LV (Prematurely Ended) NL (Completed) GR (Completed) GB (Completed) PL (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2005-001306-87 Sponsor Protocol Number: CANc/CHF14/TIF Start Date*: 2005-06-13
    Sponsor Name:TAKEDA
    Full Title: EFFECTS OF CANDESARTAN CILEXETIL VS STANDARD THERAPY ON SERUM LEVELS OF BRAIN NATRIURETIC PEPTIDE IN PATIENTS SUFFERING FROM CHRONIC HEART FAILURE WITH DEPRESSED AND PRESERVED SYSTOLIC FUNCTION
    Medical condition: CHRONIC HEART FAILURE
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024120 Left ventricular failures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015005-39 Sponsor Protocol Number: MW005 Start Date*: 2009-11-03
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Monocentric prospective randomized controlled open phase IV study to explorate the mechanismen of the synergetic effect of the Crateagus -Extract WS® 1442 in addition to endurance training related ...
    Medical condition: heart failure, stage NYHA II
    Disease: Version SOC Term Classification Code Term Level
    12.0 10019279 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002150-12 Sponsor Protocol Number: DANSVIGT Start Date*: 2017-10-11
    Sponsor Name:Danish Society of Cardiology, Heart Failure Working Group
    Full Title: DanHeart (H-HeFT / Met-HeFT)
    Medical condition: Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-000884-17 Sponsor Protocol Number: MOME Start Date*: 2016-07-20
    Sponsor Name:Dr Alberto Domínguez-Rodríguez
    Full Title: A multicenter, open-label, randomized of MOrphine and MEperidine in patients admitted for acute heart failure in emergency departments: the MOME study
    Medical condition: Acute heart failure is the rapid development or change of signs and symptoms of heart failure that requires medical attention and usually leads to patient hospitalization
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-001604-17 Sponsor Protocol Number: APHP220428 Start Date*: 2022-11-15
    Sponsor Name:Assistance Publique - Hôpitaux de Paris
    Full Title: Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers
    Medical condition: Patients With Acute Heart Failure and Elevated Inflammatory Markers in Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003460-13 Sponsor Protocol Number: GN16CA007 Start Date*: 2018-02-13
    Sponsor Name:NHS Greater Glasgow and Clyde [...]
    1. NHS Greater Glasgow and Clyde
    2. University of Glasgow
    Full Title: The effects of sacubitril/valsartan compared to valsartan on left ventricular remodelling in patients with asymptomatic left ventricular systolic dysfunction after myocardial infarction: a randomi...
    Medical condition: Asymptomatic (New York Heart Association ≤2) left ventricular systolic dysfunction (defined as ejection fraction ≤40% measured by Simpson's biplane using transthoracic echocardiography) at least 3...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019279 Heart failure LLT
    20.1 10007541 - Cardiac disorders 10064079 Heart failure NYHA class I LLT
    20.0 10007541 - Cardiac disorders 10069501 Left ventricular systolic dysfunction LLT
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002695-45 Sponsor Protocol Number: 15-156 Start Date*: 2018-05-16
    Sponsor Name:RWTH Aachen University represented by the Rector, himself, represented by the Dean of the Medical Faculty
    Full Title: Effect of Empagliflozin on Cardiac Output in Patients with Acute Heart Failure (EMPA Acute Heart Failure)
    Medical condition: Patients with acute heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Wed Jun 18 01:31:35 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA