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Clinical trials for Acute illness

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    392 result(s) found for: Acute illness. Displaying page 1 of 20.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2005-004503-11 Sponsor Protocol Number: DACO-016 Start Date*: 2006-09-14
    Sponsor Name:Eisai Medical Research Inc.
    Full Title: Randomized Phase 3 Trial of Decitabine Versus Patient's Choice with Physician's Advice of Either Supportive Care or Low-dose Cytarabine for the Treatment of Older Patients with Newly Diagnosed Acut...
    Medical condition: Acute Myloid Leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000880 Acute myeloid leukaemia LLT
    9.1 10000886 Acute myeloid leukemia LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: HU (Completed) ES (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-005803-16 Sponsor Protocol Number: GITMOAMLR.2 Start Date*: 2007-12-24
    Sponsor Name:GITMO (GRUPPO ITALIANO DI MIDOLLLO OSSEO)
    Full Title: RANDOMIZED STUDY COMPARING INTRAVENOUS BUSULFAN (I.V. BU; BUSILVEX) PLUS FLUDARABINE (BUFLU) VERSUS INTRAVENOUS BUSULFAN PLUS CYCLOPHOSPHAMIDE (BUCY2) AS CONDITIONING REGIMENS PRIOR TO ALLOGENEIC H...
    Medical condition: Acute Myeloid Leukemia (AML)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10000880 Acute myeloid leukaemia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005239-80 Sponsor Protocol Number: 10007 Start Date*: 2005-12-23
    Sponsor Name:University Hospitals Leicester, Leicester General Hospital
    Full Title: Prospective study to assess the emergence of drug resistance to oseltamivir following treatment of acute influenza A among children
    Medical condition: Influenza A
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-003733-24 Sponsor Protocol Number: EPO2008-02 Start Date*: 2009-05-29
    Sponsor Name:Abertawe Bro Morgannwg University NHS Trust
    Full Title: A randomised study to assess the effects of Epoetin Beta on renal function in patients with critical illness(with or without multi-organ failure)
    Medical condition: Sepsis/Acute renal failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-000228-33 Sponsor Protocol Number: GN12NE462 Start Date*: 2013-11-07
    Sponsor Name:NHS Greater Glasgow & Clyde [...]
    1. NHS Greater Glasgow & Clyde
    2. The University of Glasgow
    Full Title: Inhibition of complement activation (eculizumab®) in Guillain-Barré Syndrome study
    Medical condition: Guillain-Barré Syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10018766 Guillain Barre syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004950-25 Sponsor Protocol Number: D-00272-CT2014001 Start Date*: 2008-01-06
    Sponsor Name:Cell Medica Ltd
    Full Title: WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study
    Medical condition: Acute Myeloid Leukaemia and Chronic Myeloid Leukaemia in adults.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009013 Chronic myeloid leukaemia PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10000880 Acute myeloid leukaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-003904-15 Sponsor Protocol Number: 20202407 Start Date*: 2020-08-27
    Sponsor Name:University of Southern Denmark
    Full Title: Using BCG vaccine to enhance non-specific protection of senior citizens during the COVID-19 pandemic. A randomized clinical trial.
    Medical condition: Healthy volunteers, senior citizens of 65 years or older. Immune system activation after BCG vaccination. Acute infections, COVID-19 and self-reported respiratory illness will be monitored.
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10084382 Coronavirus disease 2019 LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-005951-40 Sponsor Protocol Number: ITHACA Start Date*: 2008-02-07
    Sponsor Name:Fundació Lluita contra la Sida
    Full Title: DINAMICA VIRAL DEL VIH-1 EN SUJETOS QUE INICIAN TERAPIA CON RALTEGRAVIR (HIV-1 VIRAL DYNAMICS IN SUBJECTS INITIATING RALTEGRAVIR THERAPY)
    Medical condition: Pacientes con infección VIH-1 (HIV-1 infection)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000807 Acute HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-000057-31 Sponsor Protocol Number: ESTUAR001 Start Date*: 2012-03-19
    Sponsor Name:THERANOR sprl
    Full Title: Multicentre, randomised, double-blind, parallel, placebo-controlled study evaluating the efficacy and safety of Early Self-Treatment of viral Upper respiratory tract infections with homeopathic ora...
    Medical condition: Viral upper respiratory tract infections
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10022004 Influenza like illness PT
    14.1 10021881 - Infections and infestations 10010106 Common cold LLT
    14.1 10021881 - Infections and infestations 10000938 Acute nasopharyngitis (common cold) LLT
    14.1 10021881 - Infections and infestations 10046300 Upper respiratory infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001076-14 Sponsor Protocol Number: K12-2020 Start Date*: 2020-04-20
    Sponsor Name:Oulu University Hospital, Oulu, Finland [...]
    1. Oulu University Hospital, Oulu, Finland
    2. University of Oulu
    Full Title: Efficacy of Streptococcus salivarius K12 oral probiotic products in preventing acute otitis media: A randomized placebo-controlled trial.
    Medical condition: Acute otitis media
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10033084 Otitis media NOS LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2005-004936-34 Sponsor Protocol Number: Atazanavir Start Date*: 2005-06-22
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Il therapeutic drug monitoring di Atazanavir in pazienti con infezione da HIV e malattia epatica terminale valutati per trapianto ortotopico di fegato
    Medical condition: Insufficienza epatica terminale con infezione HIV
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000807 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000728-18 Sponsor Protocol Number: VT002 Start Date*: 2005-02-21
    Sponsor Name:AISAR ASSOCIAZIONE ITALIANA PER LO STUDIO DEGLI ANTIMICROBICI E DELLE RESISTENZE
    Full Title: An experiment of phase II open label about safety and Mifepristone vgx-410 anti-HIV activity on patients affected by HIV-1
    Medical condition: Anti-HIV drug
    Disease: Version SOC Term Classification Code Term Level
    10000807 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020657-14 Sponsor Protocol Number: ALF-5755_P2_ALF Start Date*: 2011-07-04
    Sponsor Name:Alfact Innovation
    Full Title: A multicentre, double-blind, randomized, placebo-controlled study to evaluate the efficacy and the safety of ALF-5755 in patients with nonacetaminophen severe acute hepatitis and early stage acute ...
    Medical condition: Acute liver failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10049844 Acute liver failure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003400-32 Sponsor Protocol Number: TAK-664-3002 Start Date*: 2022-11-21
    Sponsor Name:Takeda
    Full Title: A Phase 3, Open-label, Non-controlled, Multi-dose, Extension Study to Evaluate the Long-term Safety and Tolerability of IGSC, 20% in Japanese Participants with Primary Immunodeficiency Disease (PID)
    Medical condition: Primary immunodeficiency diseases (PID)
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-000160-42 Sponsor Protocol Number: M2016 Start Date*: 2016-05-17
    Sponsor Name:UK für Anästhesiologie und allgemeine Intensivmedizin
    Full Title: Effect of inhaled budenoside on the incidence and severity of Acute Mountain Sickness at 4559 m
    Medical condition: Healthy volunteer trial at 4459m to investigate the effect of inhaled budenoside on the incidence and severity of Acute Mountain Sickness.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10020045 High altitude illness LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002014-39 Sponsor Protocol Number: RTB-101-205 Start Date*: 2019-08-30
    Sponsor Name:resTORbio, Inc.
    Full Title: A Multicenter, Randomized, Double Blind, Placebo-Controlled, Phase 3 Study to Determine if RTB101 Prevents Clinically Symptomatic Respiratory Illness in the Elderly
    Medical condition: Clinically Symptomatic Respiratory Illness in the Elderly
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-004008-37 Sponsor Protocol Number: Gandalf-01 Start Date*: 2013-07-05
    Sponsor Name:GITMO
    Full Title: A phase II multicentre open-label study on allogeneic stem cell transplantation from unrelated, cord-blood and family haploidentical donors in patients with active acute leukemia
    Medical condition: Any active acute leukemia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10000835 Acute leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002513-11 Sponsor Protocol Number: 331-10-230 Start Date*: 2012-01-09
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc.
    Full Title: A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Fixed dose OPC-34712 (4, 2, and 1 mg/day) in the Treatment of Adults With Acute Schizophrenia
    Medical condition: Acute Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    14.0 10037175 - Psychiatric disorders 10001064 Acute schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2011-002538-38 Sponsor Protocol Number: 331-10-231 Start Date*: 2011-10-14
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc.
    Full Title: A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Three Fixed Doses of OPC-34712 in the Treatment of Adults With Acute Schizophrenia
    Medical condition: Acute Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10001064 Acute schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: LV (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2014-001863-11 Sponsor Protocol Number: EWO-ISO-2014/1 Start Date*: 2014-09-24
    Sponsor Name:Ewopharma AG.
    Full Title: A Phase 4, Randomised, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacy of Isoprinosine® in Comparison With Placebo in Subjects With Confirmed Acute Respiratory Viral Infect...
    Medical condition: Acute Respiratory Viral Infections due to influenza A or B virus, RSV, adenovirus, or parainfluenza virus 1 or 3
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004862 10022005 Influenza viral infections HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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