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Clinical trials for Antiplatelet

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    209 result(s) found for: Antiplatelet. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2021-001905-66 Sponsor Protocol Number: BA-SCAD Start Date*: 2021-07-06
    Sponsor Name:Spanish Cardiology Society
    Full Title: Randomized clinical trial assessing the value of Beta-Blockers and Antiplatelet Agents in patients with Spontaneous Coronary Artery Dissection
    Medical condition: Spontaneous Coronary Artery Dissection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000017-20 Sponsor Protocol Number: ASS-Metamizol-DDI Start Date*: 2018-07-17
    Sponsor Name:Universitäts-Herzzentrum Freiburg • Bad Krozingen
    Full Title: Antiplatelet effect of acetylsalicylic acid in patients after cardiac surgery: Impact of dipyrone (metamizole)
    Medical condition: Antithrombotic therapy after surgical replacement of stenotic heart valve by a bioprosthesis or mitral valve repair
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024667-40 Sponsor Protocol Number: PGxSTEMI08 Start Date*: 2019-04-23
    Sponsor Name:St. Antonius Hospital
    Full Title: Cost-effectiveness of CYP2C19 guided treatment with antiplatelet drugs in patients with ST-segment-elevation myocardial infarction undergoing immediate percutaneous coronary intervention with stent...
    Medical condition: ST-segment myocardial infarction (STEMI) followed by immediate percutaneous coronary intervention with stent implantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-002142-50 Sponsor Protocol Number: POPCABG03 Start Date*: 2019-04-09
    Sponsor Name:St. Antonius Hospital
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Trial Investigating The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery.
    Medical condition: Coronary artery bypass grafting surgery with the use of one or more saphenous vein grafts.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005149-18 Sponsor Protocol Number: 033 Start Date*: 2021-04-26
    Sponsor Name:Medical University of Vienna
    Full Title: Preclinical antiplatelet treatment with Cangrelor in patients presenting with ST-Elevation myocardial infarction: a randomized, double-blind, placebo-controlled pilot trial
    Medical condition: ST-Elevation Myocardial Infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001067-27 Sponsor Protocol Number: 20604 Start Date*: 2022-11-10
    Sponsor Name:Bayer AG
    Full Title: A multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of i...
    Medical condition: Prevention of ischemic stroke in patients post acute non-cardioembolic ischemic stroke or high-risk transient ischemic attack
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10049165 Cerebrovascular accident prophylaxis PT
    22.1 100000004852 10055221 Ischemic stroke LLT
    20.1 100000004852 10072760 Transient ischemic attack LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned) FI (Trial now transitioned) SE (Trial now transitioned) NO (Trial now transitioned) LT (Trial now transitioned) HU (Trial now transitioned) ES (Trial now transitioned) AT (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned) BE (Trial now transitioned) GR (Trial now transitioned) CZ (Trial now transitioned) NL (Trial now transitioned) PL (Trial now transitioned) LV (Trial now transitioned) PT (Trial now transitioned) BG (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-001013-32 Sponsor Protocol Number: CV-185-685 Start Date*: 2018-11-08
    Sponsor Name:HOSPITAL CLÍNIC BARCELONA
    Full Title: ANTITHROMBOTIC THERAPY AFTER LEFT ATRIAL APPENDAGE OCCLUSION: DOUBLE ANTIPLATELET THERAPY VS. APIXABAN
    Medical condition: ATRIAL FIBRILLATION IN PATIENTS AFTER OCCLUSION OF THE LEFT ATRIAL APPENDAGE (LAAC)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005042-11 Sponsor Protocol Number: ISSBRIL0205 Start Date*: 2014-06-11
    Sponsor Name:Fundación Investigación Sanitaria en León
    Full Title: EndoTic ? Endothelium and Ticagrelor: Pharmacological effects beyond antiplatelet effect
    Medical condition: The use of ticagrelor in ACS is related to a reduction in the number of CECs and/or an increase in the number of EPCs from the baseline values as compared with clopidogrel.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005174-23 Sponsor Protocol Number: CAVA2Dec04 Start Date*: 2005-04-11
    Sponsor Name:NHS Grampian
    Full Title: Is smooth muscle mitogenesis down regulated by platelet inactivation with combination antiplatelet therapy after angioplasty for claudication?
    Medical condition: Intermittent claudication = stenosis of superficial femoral artery requiring percutaneous angioplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011907-22 Sponsor Protocol Number: ED09/8912 Start Date*: 2010-02-10
    Sponsor Name:University of Leeds
    Full Title: Antiplatelet treatment in patients with diabetes mellitus: is there a difference between aspirin, clopidogrel and prasugrel
    Medical condition: Type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-003190-26 Sponsor Protocol Number: RESTART13 Start Date*: 2013-01-14
    Sponsor Name:ACCORD (Academic and Clinical Central Office for Research & Development) [...]
    1. ACCORD (Academic and Clinical Central Office for Research & Development)
    2. ACCORD (Academic and Clinical Central Office for Research & Development)
    Full Title: REstart or STop Antithrombotics Randomised Trial (RESTART)
    Medical condition: Spontaneous Intracerebral Haemorrhage (ICH)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10022753 Intracerebral haemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2021-006611-29 Sponsor Protocol Number: 80009 Start Date*: 2022-06-28
    Sponsor Name:University Medical Centre Utrecht Department of Vascular Surgery
    Full Title: A randomized placebo-controlled double-blind trial studying the effect of antiplatelet monotherapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel + aspirin) on the occurrence of athero...
    Medical condition: (Chronic) Peripheral (occlusive) arterial disease (PAD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-001093-55 Sponsor Protocol Number: NL77315.078.21 Start Date*: 2022-10-03
    Sponsor Name:Erasmus Medical center
    Full Title: COATS study: genetic Clopidogrel response testing to finetune the antithrombotic regimen in (D)OAC Treated patients undergoing PCI
    Medical condition: Patients on oral anticoagulation drugs who undergo a percutaneous coronary intervention (PCI) temporarily and treatment with concomitant antiplatelet therapy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-001332-11 Sponsor Protocol Number: IRELANDPILOTV1 Start Date*: 2014-07-30
    Sponsor Name:Royal College of Surgeons
    Full Title: Aspirin for Optimising Pregnancy Outcome in Pregestational Diabetes: Pilot for The IRELAND Study (Investigating the Role of Early Low-dose Aspirin iN preexisting Diabetes)
    Medical condition: Pregestational diabetes represents a high-risk for evolution of preeclampsia (PET), with rates of PET within this group at approximately 20%. The combination of diabetes and preeclampsia places the...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003599-21 Sponsor Protocol Number: MEIXO-VALV-002 Start Date*: 2015-06-27
    Sponsor Name:Sociedad Española de Cardiología
    Full Title: Platelet reactivity after TAVI: A multicenter randomized clinical trial
    Medical condition: Study platelet reactivity in patients with Aortic Stenosis (AS) selected for TAVI and to assess the effectiviness of ticagrelor as antiplatelet monotherapy for the supression of high platelet react...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001904-12 Sponsor Protocol Number: 18040 Start Date*: Information not available in EudraCT
    Sponsor Name:University of Nottingham
    Full Title: Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH)
    Medical condition: Intracerebral haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-000112-33 Sponsor Protocol Number: NL47761.041.14 Start Date*: 2014-09-01
    Sponsor Name:University Medical Center Utrecht
    Full Title: Apixaban versus antiplatelet drugs or no antithrombotic drugs after anticoagulation-associated intracerebral haemorrhage in patients with atrial fibrillation. A randomised phase II clinical trial.
    Medical condition: The prevention of ischaemic stroke in patients with atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022461-10 Sponsor Protocol Number: Final Version1 Start Date*: 2011-02-08
    Sponsor Name:Southampton University Hospitals NHS Trust
    Full Title: A pilot study investigating the antiplatelet effect of generic clopidogrel versus Plavix™ – is there any difference in platelet reactivity in healthy subjects?
    Medical condition: The intended indication for the product is for use in all patients with acute coronary syndromes and following coronary artery stenting
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-004238-25 Sponsor Protocol Number: 2012-004-0402-CARD Start Date*: 2015-02-09
    Sponsor Name:The Royal Wolverhampton NHS Trust
    Full Title: Pharmacokinetics and Pharmacodynamics of Platelet P2Y12 Inhibitors in Patients Undergoing Percutaneous Coronary Intervention (PCI) for Acute Myocardial Infarction: A Pilot Study
    Medical condition: ST-segment elevation myocardial infarction Non ST-segment elevation myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10053460 Antiplatelet therapy PT
    17.1 100000004849 10064347 Non ST segment elevation myocardial infarction LLT
    17.1 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-000195-19 Sponsor Protocol Number: 2015CAR77 Start Date*: 2016-03-31
    Sponsor Name:The Royal Wolverhampton NHS Trust
    Full Title: The Effect of Intravenous Cangrelor and Oral Ticagrelor on Platelets, the Microcirculation and Myocardial Damage in Patients admitted with STEMI Treated by Primary Percutaneous Coronary Interventio...
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10053460 Antiplatelet therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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