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Clinical trials for Anxiety AND Depression

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    556 result(s) found for: Anxiety AND Depression. Displaying page 1 of 28.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2013-000426-62 Sponsor Protocol Number: CHDR1203-E Start Date*: 2013-04-10
    Sponsor Name:Centre for Human Drug Research
    Full Title: A randomized, double blind, placebo-controlled crossover study to investigate the effects of a selective serotonergic reuptake inhibitor on resting state fMRI in healthy volunteers.
    Medical condition: healthy volunteers 'depression, anxiety'
    Disease: Version SOC Term Classification Code Term Level
    15.1 10037175 - Psychiatric disorders 10012378 Depression PT
    15.1 10037175 - Psychiatric disorders 10002855 Anxiety PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2012-000438-21 Sponsor Protocol Number: 750201.01.035 Start Date*: 2012-10-17
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Multi-center, double-blind, placebo-controlled, randomized phase III study to prove the efficacy, safety and tolerability of Silexan (WS®1265) in patients with mixed anxiety and depressive disorder...
    Medical condition: mixed anxiety and depressive disorder (ICD-10, F41.2)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004873 10027741 Mixed anxiety & depressive LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022460-12 Sponsor Protocol Number: MVH-03 Start Date*: 2011-03-23
    Sponsor Name:Herlev Hospital
    Full Title: The effect of melatonin on depression, anxiety, cogntive function and sleep disturbances in breast cancer patients
    Medical condition: Depression Anxiety Postoperative cognitive dysfunction Sleep disturbances
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012378 Depression LLT
    12.1 10002855 Anxiety LLT
    12.1 10009845 Cognitive disturbance LLT
    12.1 10040997 Sleep disturbances LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-001666-15 Sponsor Protocol Number: CL3-20098-087 Start Date*: 2013-06-11
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efficacy and safety of 2 doses of agomelatine (10 mg/day or 25 mg/day) versus placebo given orally for 12 weeks in non depressed out-patients with Generalized Anxiety Disorder. A 12-week randomise...
    Medical condition: Generalized Anxiety Disorder
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004873 10018105 Generalized anxiety disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2015-002116-32 Sponsor Protocol Number: MTM-04 Start Date*: 2015-09-23
    Sponsor Name:Køge Hospital
    Full Title: The effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep disturbances in patients after acute myocardial syndrome
    Medical condition: Depression Anxiety Sleep disturbances Circadian disturbances
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004852 10009190 Circadian dysrhythmia LLT
    19.0 100000004873 10002865 Anxiety reaction LLT
    19.0 100000004873 10040999 Sleep disturbed LLT
    19.0 100000004873 10012402 Depressive episode LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-020332-19 Sponsor Protocol Number: Prot-22121988-2010 Start Date*: 2010-08-23
    Sponsor Name:ERASMUS MC, Dept Anesthesiology
    Full Title: Putting Resistance under the Microscope. (Weerstand onder de Loep)
    Medical condition: Patients resistance concerning diagnostic or therapeutic procedure are well known. In this trial patients-resistance during the perioperative period will be investigated in day-case-surgery. Feat...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002865 Anxiety reaction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003404-12 Sponsor Protocol Number: CL2-20098-075 Start Date*: 2013-02-12
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Pharmacokinetics and safety of agomelatine in children (from 7 to less than 12 years) and adolescents (from 12 to less than 18 years) with Depressive or Anxiety Disorder. An open-labelled, multice...
    Medical condition: Depressive or Anxiety Disorder
    Disease: Version SOC Term Classification Code Term Level
    17.0 10037175 - Psychiatric disorders 10057666 Anxiety disorder PT
    17.0 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) HU (Completed) EE (Completed) RO (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2005-005597-67 Sponsor Protocol Number: EFC4846 Start Date*: 2006-03-29
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: An eight-week, double-blind placebo controlled, multicenter study evaluating the efficacy, safety, tolerability of a fixed dose of SR58611A (350 mg q12) in elderly patients with Major Depressive Di...
    Medical condition: Major Depressive Disorder (MDD)
    Disease: Version SOC Term Classification Code Term Level
    8.0 10018105 LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2009-013789-17 Sponsor Protocol Number: CL3-20098-071 Start Date*: 2010-03-11
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efficacy and safety of agomelatine (25 mg/day with potential blinded adjustment to 50 mg/day) for 12 weeks in non-depressed out-patients with Generalized Anxiety Disorder. A 12-week randomised, dou...
    Medical condition: Generalized anxiety disorder
    Disease: Version SOC Term Classification Code Term Level
    13.1 10037175 - Psychiatric disorders 10018105 Generalized anxiety disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2014-004475-23 Sponsor Protocol Number: 47410 Start Date*: 2016-10-05
    Sponsor Name:Radboud University Nijmegen
    Full Title: Enhancement of exposure therapy for social anxiety disorder with testosterone: A randomized clinical trial
    Medical condition: Social Anxiety Disorder (Social Phobia)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10037175 - Psychiatric disorders 10041250 Social phobia PT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006121-26 Sponsor Protocol Number: 40411813DAX2001 Start Date*: 2012-06-06
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Multicenter, Double-Blind, Placebo-Controlled Study of JNJ-40411813 as Adjunctive Treatment to an Antidepressant in Adults with Major Depressive Disorder with Anxiety Symptoms
    Medical condition: Major Depressive Disorder with Anxiety Symptoms
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004873 10025454 Major depressive disorder, recurrent episode LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) BG (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2007-004768-32 Sponsor Protocol Number: A0081147 Start Date*: 2008-04-21
    Sponsor Name:Pfizer S.A.
    Full Title: “ESTUDIO DE SEGURIDAD Y EFICACIA A LARGO PLAZO DE PREGABALINA EN SUJETOS CON TRASTORNO DE ANSIEDAD GENERALIZADA” "LONG TERM SAFETY AND EFFICACY STUDY OF PREGABALIN IN SUBJECTS WITH GENERALIZED ANX...
    Medical condition: Trastorno de ansiedad generalizada (TAG)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018105 Generalized anxiety disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) LT (Completed) FI (Completed) AT (Completed) CZ (Completed) SI (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2021-006879-42 Sponsor Protocol Number: GH001-PPD-203 Start Date*: 2022-08-30
    Sponsor Name:GH Research Ireland Limited
    Full Title: A phase 2 clinical trial of GH001 in patients with postpartum depression
    Medical condition: Post-Partum Depression
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10056393 Postpartum depression LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003659-19 Sponsor Protocol Number: R317573DEP2002 Start Date*: 2006-09-14
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Double Blind, Placebo- and Active-Controlled, Randomized, Sequential Group, Multiple Dose Study to Examine the Effect of the CRF1-Receptor Antagonist R317573 on 7.5% CO2-Inhalation Induced Anxiet...
    Medical condition: Anxiety disorders and depression
    Disease: Version SOC Term Classification Code Term Level
    8.1 10057666 Anxiety disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004960-64 Sponsor Protocol Number: F1J-MC-HMDW(b) Start Date*: 2005-05-13
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: A Comparison of Duloxetine Hydrochloride, Venlafaxine Extended Release, and Placebo in the Treatment of Generalized Anxiety Disorder
    Medical condition: Generalised Anxiety Disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001424-34 Sponsor Protocol Number: 217-PPD-301 Start Date*: 2020-11-23
    Sponsor Name:Sage Therapeutics, Inc.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF SAGE-217 IN THE TREATMENT OF ADULTS WITH SEVERE POSTPARTUM DEPRESSION
    Medical condition: POSTPARTUM DEPRESSION
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10056393 Postpartum depression LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2006-003643-23 Sponsor Protocol Number: CRO-06-76 - AB/GAD/21 Start Date*: 2006-06-14
    Sponsor Name:Abiogen Pharma S.p.A.
    Full Title: Efficacy and tolerability study of a novel CNS drug ABIO 08/01 administered for 8 weeks to patients with generalised anxiety disorders
    Medical condition: generalised anxiety disorder
    Disease: Version SOC Term Classification Code Term Level
    8.1 10017571 GAD LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004006-81 Sponsor Protocol Number: LTE5376 Start Date*: 2006-06-01
    Sponsor Name:sanofi-aventis recherche&developpement
    Full Title: A double-blind, 6 to 12-month, multicenter, multinational, randomized study evaluating the efficacy and safety of SR58611A (350 mg q12) versus placebo in the prevention of relapse / recurrence of d...
    Medical condition: patients with major depressive disorder
    Disease: Version SOC Term Classification Code Term Level
    8.0 10018105 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SK (Completed) FI (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2015-002007-29 Sponsor Protocol Number: 42165279MDD2001 Start Date*: 2015-11-24
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Phase 2a Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multi-center Study Investigating the Efficacy, Safety, and Tolerability of JNJ-42165279 in Subjects with Major Depressive Di...
    Medical condition: Major Depressive Disorder Anxiety
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004873 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001766-90 Sponsor Protocol Number: LuAA21004_311 Start Date*: 2009-04-09
    Sponsor Name:Takeda Global Research & Development Centre (Europe) Ltd.
    Full Title: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed-Dose Study Comparing the Efficacy and Safety of a Single Dose of Lu AA21004 in Acute Treatment of Adults With Generalized Anxie...
    Medical condition: Generalized Anxiety Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018075 Generalised anxiety disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Completed) LV (Completed) EE (Completed) LT (Completed) PL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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