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Clinical trials for Blood volume

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,572 result(s) found for: Blood volume. Displaying page 1 of 79.
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    EudraCT Number: 2013-004446-42 Sponsor Protocol Number: AIR Start Date*: 2014-02-09
    Sponsor Name:Skåne University Hospital
    Full Title: THE IMPORTANCE OF ALBUMIN INFUSION RATE FOR PLASMA VOLUME EXPANSION FOLLOWING MAJOR ABDOMINAL SURGERY
    Medical condition: Post operative patients who have been subjected to either a non-emergant Whipple operation or major gynecological cancer surgery ( including resection of ovaries, uterus, adnexa, oment and lymph ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002455-26 Sponsor Protocol Number: IRON-CMR Start Date*: 2014-09-20
    Sponsor Name:Karolinska Institute
    Full Title: The use of intravenous Iron oxide as a contrast agent for cardiac magnetic resonance imaging.
    Medical condition: Cardiovascular diseases: Acute myocardial infarction, chronic myocardial infarction, myocardial ischemia, myocarditis, diffuse myocardial fibrosis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004175-22 Sponsor Protocol Number: HC-G-H-0803 Start Date*: Information not available in EudraCT
    Sponsor Name:B. Braun Melsungen AG
    Full Title: PROSPECTIVE, CONTROLLED, DOUBLE-BLIND, RANDOMIZED MULTICENTRIC STUDY ON THE EFFICACY AND SAFETY OF A TARGET CONTROLLED PLASMA VOLUME REPLACEMENT THERAPY WITH A HYPER-ONCOTIC BALANCED HES 130/0.42...
    Medical condition: Intraoperative plasma volume replacement requirement in elective surgery of the pancreatic head (pylorus preserving pancreatic-duodenectomy, PPPD)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022891 - Investigations 10059909 Volume plasma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004512-11 Sponsor Protocol Number: FJD-VITDAMI-14-01 Start Date*: 2015-08-06
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA FJD
    Full Title: Multicenter, randomized, double-blind, placebo-controlled study to evaluate the effect of vitamin D on ventricular remodeling in patients with acute myocardial infarction: Test VITDAMI (Vitamin D i...
    Medical condition: Acute myocardial infarction with ST segment elevation anterior
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002096-16 Sponsor Protocol Number: 01/04 Start Date*: 2005-05-23
    Sponsor Name:Universitätskinderklinik Innsbruck
    Full Title: Effect of plasma volume expansion with hydroxy-ethyl-starch (HES) 130/0.4 or crystalloids on interstitial fluid accumulation and blood pressure in newborn infants with arterial hypotension
    Medical condition: Arterial hypotension
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008597-31 Sponsor Protocol Number: Start Date*: 2010-08-17
    Sponsor Name:Malmoe University Hospital
    Full Title: Comparative study to evaluate the effects of racemic ketamin versus s-ketamine on cerebral blood flow, blood volume and metabolism
    Medical condition: Racemic ketamine is used for sedation, analgesia and anesthesia to patients in various forms of circulatory compromise ie shock. The enantiomere S-ketamine has not been compared regarding cerebral ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002162-30 Sponsor Protocol Number: HC-G-H-1504 Start Date*: 2017-04-12
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Prospective, randomized, controlled, double-blind, multicentre, multinational study on the safety and efficacy of 6% Hydroxyethyl starch (HES) solution versus an electrolyte solution in patients u...
    Medical condition: Hypovolaemia due to acute blood loss in elective abdominal surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10021137 Hypovolaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) NL (Completed) ES (Restarted) FR (Ongoing) AT (Completed) HR (Completed) RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2006-000867-27 Sponsor Protocol Number: HDPET Start Date*: 2006-05-04
    Sponsor Name:University Medical Center Groningen
    Full Title: Gated 13N-NH3 PET before and during hemodialysis for the assessment of changes in myocardial perfusion, volumes and output of the left ventricle
    Medical condition: Hemodialysis patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002176-27 Sponsor Protocol Number: HC-G-H-1505 Start Date*: 2017-08-30
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Pragmatic, prospective, randomized, controlled, double-blind, multicentre, multinational study on the safety and efficacy of a 6% Hydroxyethyl starch (HES) solution versus an electrolyte solution ...
    Medical condition: Hypovolaemia due to acute blood loss in trauma surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10021137 Hypovolaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) CZ (Completed) NL (Completed) ES (Restarted) FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2018-000748-24 Sponsor Protocol Number: -- Start Date*: 2018-08-09
    Sponsor Name:VUmc
    Full Title: Partial neuromuscular blockade to facilitate lung and diaphragm protective mechanical ventilation in ICU patients. A randomized controlled pilot study.
    Medical condition: Some patients develop high respiratory drive during partially supported mechanical ventilation which is associated with lung and diaphragm injury and worse clinical outcome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-008354-23 Sponsor Protocol Number: ECAL-CCPB-08-07 Start Date*: 2009-04-30
    Sponsor Name:Cubist Pharmaceuticals,INC
    Full Title: CONSERVTM – 2 (Clinical Outcomes and Safety Trial to Investigate Ecallantide’s Effect on Reducing Surgical Blood Loss Volume) – A Phase 2 Randomized Double-Blind Active-Controlled Study in Subjects...
    Medical condition: Reduction of blood loss in subjects exposed to CPB during cardiac surgery at high risk for bleeding
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004192-41 Sponsor Protocol Number: A0221109 Start Date*: 2020-09-03
    Sponsor Name:Pfizer
    Full Title: LONG-TERM EXTENSION STUDY TO EVALUATE THE SAFETY OF FESOTERODINE IN JAPANESE PEDIATRIC SUBJECTS WITH SYMPTOMS OF DETRUSOR OVERACTIVITY ASSOCIATED WITH A NEUROLOGICAL CONDITION (NEUROGENIC DETRUSOR ...
    Medical condition: Urinary Bladder, Neurogenic
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-005577-36 Sponsor Protocol Number: neopopgen_v1.0 Start Date*: 2015-04-02
    Sponsor Name:Teijo Saari
    Full Title: Individualising propofol and oxycodone therapy in neonates using pharmacogenomic profiling, population based modeling and simulations.
    Medical condition: Neonates, who need to be intubated and ventilated with a ventilator.
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005040-85 Sponsor Protocol Number: HaHes Start Date*: 2006-03-17
    Sponsor Name:Department of Anesthesia, Div. of Cardiothoracic and Vascular Anesthesia, Medical University Vienna
    Full Title: Comparison of Albumin 5%, Hydroxyethyl Starch 130/0.4 (6%) and Ringer Lactate for volume replacement during cardiac surgery
    Medical condition: Intensive care patients after cardiac surgery requiring volume therapy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003260-32 Sponsor Protocol Number: 13090 Start Date*: 2013-12-04
    Sponsor Name:
    Full Title: The Effects of Isovolumetric and Isoeffective Infusions of Colloid Versus Crystalloid on Renal Blood Flow and Cardiac Output
    Medical condition: Anaesthesia
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-013159-31 Sponsor Protocol Number: CS/2009/3292 Start Date*: 2010-02-25
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: Preoperative volume replacement vs. usual care in diabetic patients having CABG surgery: a randomised controlled trial
    Medical condition: Coronary artery bypass grafting in diabetic patients
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-003398-24 Sponsor Protocol Number: FP2012/01 Start Date*: 2012-10-29
    Sponsor Name:FUNDACIÓ PUIGVERT
    Full Title: Randomized clinical trial to compare the effect of mannitol and hydroelectrolytic solutions as kidney function protector, in partial laparoscopic nephrectomies (MANCOL Study)
    Medical condition: partial laparoscopic nephrectomy
    Disease: Version SOC Term Classification Code Term Level
    15.0 10027433 - Metabolism and nutrition disorders 10047691 Volume depletion LLT
    15.0 10042613 - Surgical and medical procedures 10034072 Partial nephrectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002122-30 Sponsor Protocol Number: 1978 Start Date*: 2007-09-14
    Sponsor Name:Medical University Vienna Division of Anesthesie and Pain Management
    Full Title: The effect of different solvents of HES preparations on coagulation and platelet function (Effekt der Trägerlösung von HES Präparaten auf Blutgerinnung und Thrombozytenfunktion)
    Medical condition: treatment and prophylaxis of acute hypovolaemia and shock acute normovolaemic haemodilution
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021139 Hypovolemia LLT
    9.1 10011954 Decreased and nonspecific blood pressure disorders and shock HLGT
    9.1 10059489 Hemodilution LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-002661-36 Sponsor Protocol Number: 15039DB-SW Start Date*: 2016-03-10
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: Single centre randomised controlled trial to assess the effect of the addition of twenty-four hours of oral tranexamic acid post-operatively to a single intra-operative intravenous dose of tranexam...
    Medical condition: Osteoarthritic patients who require hip or knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021983-14 Sponsor Protocol Number: MLK002 Start Date*: 2010-09-23
    Sponsor Name:UZ Gasthuisberg
    Full Title: A randomized placebo-controlled double blind study to treat BOS.
    Medical condition: -Mortality at 1 and 2 year post diagnosis of BOS -Infection rate during BOS -Evolution of pulmonary function after diagnosis of BOS
    Disease: Version SOC Term Classification Code Term Level
    12.1 10029888 Obliterative bronchiolitis LLT
    12.1 10049202 Bronchiolitis obliterans LLT
    12.1 10068805 Follicular bronchiolitis LLT
    12.1 10019319 Heart-lung transplant rejection LLT
    12.1 10025127 Lung transplant LLT
    12.1 10051604 Lung transplant rejection LLT
    12.1 10056409 Heart and lung transplant LLT
    12.1 10016547 FEV LLT
    12.1 10016549 FEV 1 abnormal LLT
    12.1 10016550 FEV 1 decreased LLT
    12.1 10016553 FEV 1 low LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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