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Clinical trials for Cangrelor

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    18 result(s) found for: Cangrelor. Displaying page 1 of 1.
    EudraCT Number: 2016-000134-22 Sponsor Protocol Number: MDCO-CAN-15-01 Start Date*: 2021-01-14
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A Prospective, Open-Label, Single-Arm, Multi-Center Study to Assess The Pharmacokinetics/Pharmacodynamics (PK/PD) AND Safety Of Different Cangrelor Doses In Neonatal Subjects At Risk Of Thrombosis.
    Medical condition: Postoperative neonatal cardiac subjects who are undergoing surgery for placement of systemic-to pulmonary artery palliative shunts (e.g., Blalock-Taussig or central shunt), right ventricle to pulmo...
    Disease:
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-002586-64 Sponsor Protocol Number: ISS13616 Start Date*: 2016-10-13
    Sponsor Name:ELKE University of Athens
    Full Title: A randomized, pharmacodynamic study of cangrelor administration in STEMI patients loaded with ticagrelor
    Medical condition: In the present study, in STEMI patients undergoing primary PCI we aim therefore to compare platelet inhibition achieved in patients loaded with ticagrelor followed by cangrelor (bolus plus infusion...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003265-26 Sponsor Protocol Number: 345 Start Date*: 2017-01-03
    Sponsor Name:Medical University of Vienna
    Full Title: Pharmacokinetic/Pharmacodynamic effects of add-on antiplatelet therapy with parenteral cangrelor as compared to standard dual antiplatelet treatment in patients with ST-elevation myocardial infarct...
    Medical condition: ST-elevation myocardial infarction, cardiac arrest
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2019-001285-15 Sponsor Protocol Number: KOIIM-2019-1 Start Date*: 2019-06-28
    Sponsor Name:University Medical Centre Ljubljana
    Full Title: Platelet inhibition with cangrelor in comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Medical condition: Comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005149-18 Sponsor Protocol Number: 033 Start Date*: 2021-04-26
    Sponsor Name:Medical University of Vienna
    Full Title: Preclinical antiplatelet treatment with Cangrelor in patients presenting with ST-Elevation myocardial infarction: a randomized, double-blind, placebo-controlled pilot trial
    Medical condition: ST-Elevation Myocardial Infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000195-19 Sponsor Protocol Number: 2015CAR77 Start Date*: 2016-03-31
    Sponsor Name:The Royal Wolverhampton NHS Trust
    Full Title: The Effect of Intravenous Cangrelor and Oral Ticagrelor on Platelets, the Microcirculation and Myocardial Damage in Patients admitted with STEMI Treated by Primary Percutaneous Coronary Interventio...
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10053460 Antiplatelet therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-002226-76 Sponsor Protocol Number: 6.1 Start Date*: 2012-11-13
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: High “on treatment” platelet reactivity in the Intensive Care Unit
    Medical condition: mixed medical intensive care unit patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-003621-36 Sponsor Protocol Number: 20-126 Start Date*: 2021-02-10
    Sponsor Name:CHU CAEN Normandie
    Full Title: Evaluation de la reperfusion myocardique et de la masse thrombotique endocoronaire après angioplastie primaire pour infarctus du myocarde sous cangrelor en intraveineux en plus du ticagrelor per os...
    Medical condition: Patients admis pour angioplastie coronaire primaire (PPCI) pour infarctus du myocarde avec sus-décalage du segment ST (IDM ST+)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005071-25 Sponsor Protocol Number: ExcelsiorLOAD2 Start Date*: 2016-01-19
    Sponsor Name:University Heart Center Freiburg - Bad Krozingen
    Full Title: Pharmacodynamic comparison of different oral P2Y12-receptor inhibitor loading strategies for transitioning from cangrelor in patients undergoing coronary stenting
    Medical condition: Patients with obstructive coronary heart disease undergoing percutaneous coronary stent implantation.
    Disease: Version SOC Term Classification Code Term Level
    18.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    18.1 100000004865 10069038 Bare metal coronary stent placement LLT
    18.1 100000004865 10069037 Drug-eluting coronary stent placement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003721-41 Sponsor Protocol Number: SKS-CANTI2016 Start Date*: 2018-03-01
    Sponsor Name:Department of Cardiology, Aarhus University Hospital, Skejby
    Full Title: Cangrelor versus Ticagrelor for Early Platelet Inhibition in ST-Elevation Myocardial Infarction. (The CanTi study)
    Medical condition: ST-elevation Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-005451-20 Sponsor Protocol Number: MMI_2020_35 Start Date*: 2021-06-03
    Sponsor Name:Fondation A. de Rothschild Hospital
    Full Title: REperfusion with P2Y12 inhibitors in addition to mEchanical thRombectomy for perFUsion imaging selected acute Stroke patiEnts : a multicentric randomized controlled trial
    Medical condition: patients with a clinical diagnosis of AIS consecutive to LVO between 0 and 24 hours of symptom onset and selected by perfusion imaging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-021591-28 Sponsor Protocol Number: TMC-CAN-10-01 Start Date*: 2011-01-05
    Sponsor Name:The Medicines Company
    Full Title: A clinical trial comparing cangrelor to clopidogrel standard of care therapy in subjects who require percutaneous coronary intervention
    Medical condition: Subjects with coronary atheroschlerosis who require PCI
    Disease: Version SOC Term Classification Code Term Level
    15.0 10007541 - Cardiac disorders 10011076 Coronary artery atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) IT (Completed) DE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2006-000192-14 Sponsor Protocol Number: TMC-CAN-05-02 Start Date*: 2006-12-21
    Sponsor Name:The Medicines Company
    Full Title: A Clinical Trial Comparing Cangrelor To Clopidogrel In Subjects Who Require Percutaneous Coronary Intervention
    Medical condition: Subjects with coronary atherosclerosis who require PCI (with or without stent).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011093 Coronary atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) ES (Completed) DE (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002161-19 Sponsor Protocol Number: 13062017-23-1 Start Date*: 2018-06-25
    Sponsor Name:Fakultní nemocnice Královské Vinohrady
    Full Title: Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction
    Medical condition: Cardiogenic shock in acute myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed) FR (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001135-35 Sponsor Protocol Number: TMC-CAN-08-02 Start Date*: 2010-02-02
    Sponsor Name:The Medicines Company
    Full Title: Maintenance of platelet inhiBition with cangreloR after dIscontinuation of thienopyriDines in patients undergoing surGEry: The BRIDGE trial
    Medical condition: Subjects who present with an acute coronary syndrome.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10051592 Acute coronary syndrome LLT
    12.0 10051592 Acute coronary syndrome PT
    12.0 10006894 CABG LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) AT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-004446-42 Sponsor Protocol Number: MB11-2018 Start Date*: 2019-06-20
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA S.CROCE E CARLE CUNEO
    Full Title: Maintenance Of aNtiplatElet Therapy in patients with coronary stenting undergoing surgery
    Medical condition: Patients a least 18 years of age on DAPT per standard of care who are planned to undergo non deferrable cardiac and non cardiac surgery which will require discontinuation of a P2Y12 inhibitor. Subj...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011082 Coronary artery disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003935-56 Sponsor Protocol Number: TMC-CAN-05-03 Start Date*: 2006-11-24
    Sponsor Name:The Medicines Company
    Full Title: A clinical trial comparing treatment with cangrelor (in combination with usual care) to usual care, in subjects who require percutaneous coronary intervention
    Medical condition: Subjects with coronary atherosclerosis (excluding ST segment-elevation MI [STEMI]) who require PCI (with or without stent).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011093 Coronary atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) ES (Completed) CZ (Prematurely Ended) LT (Completed) SK (Completed) DE (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001065-24 Sponsor Protocol Number: FABOLUSFASTER Start Date*: 2018-07-27
    Sponsor Name:INSEL GRUPPE AG, BERN UNIVERSITY HOSPITAL, DEPARTMENT OF CARDIOLOGY
    Full Title: Facilitation through Aggrastat or cangrelor Bolus and infusion Over prasugreL: a muUlticenter randomized open-label trial in patientS with ST-elevation myocardial inFarction referred for primAry pe...
    Medical condition: myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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