- Trials with a EudraCT protocol (1,412)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
1,412 result(s) found for: Cell body.
Displaying page 1 of 71.
EudraCT Number: 2006-005889-40 | Sponsor Protocol Number: ABR-15108 | Start Date*: 2007-08-14 | |||||||||||
Sponsor Name:Academic Medical Centre | |||||||||||||
Full Title: N-Acetylcysteine for Treatment of Sickle Cell Disease | |||||||||||||
Medical condition: Patients homozygous for sickle cell disease | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-004568-37 | Sponsor Protocol Number: INV543 | Start Date*: 2018-11-30 | ||||||||||||||||
Sponsor Name:Nova Laboratories Limited | ||||||||||||||||||
Full Title: A prospective open label, pharmacokinetic study of an oral hydroxyurea solution in children with sickle cell anemia | ||||||||||||||||||
Medical condition: Sickle Cell Anaemia | ||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | |||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-003485-39 | Sponsor Protocol Number: NN7533-4470 | Start Date*: 2022-07-19 | |||||||||||
Sponsor Name:Novo Nordisk A/S | |||||||||||||
Full Title: A multicentre trial evaluating the efficacy and safety of oral decitabine-tetrahydrouridine (NDec) in patients with sickle cell disease | |||||||||||||
Medical condition: Sickle cell disease | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GR (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2006-004851-39 | Sponsor Protocol Number: 109/2006/U/Sper | Start Date*: 2006-10-03 | |||||||||||
Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI | |||||||||||||
Full Title: A PHASE II, OPEN-LABEL, PROSPECTIVE, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF SUBSEQUENT TREATMENT WITH THE ZEVALIN (IBRITUMOMAB TIUXETAN) IN ELDERLY ( 60 YEARS) PATIENTS WITH DI... | |||||||||||||
Medical condition: DIFFUSE LARGE BCELL LYMPHOMA | |||||||||||||
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Population Age: Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-004045-25 | Sponsor Protocol Number: GBT440-034 | Start Date*: 2018-04-17 | |||||||||||
Sponsor Name:Global Blood Therapeutics, Inc. | |||||||||||||
Full Title: An Open Label Extension Study of Voxelotor (GBT440) Administered Orally to Participants with Sickle Cell Disease Who Have Participated in Voxelotor Clinical Trials | |||||||||||||
Medical condition: Sickle Cell Disease | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) FR (Completed) NL (Completed) IT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-001006-18 | Sponsor Protocol Number: D5136C00007 | Start Date*: 2014-08-27 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: Multicenter, open-label, randomised, pharmacokinetic (PK) and pharmacodynamic (PD) dose-ranging Phase II study of ticagrelor followed by a double-blind, randomised, parallel-group, placebo-controll... | |||||||||||||
Medical condition: Investigation of platelet aggregation in paediatric patients with sickle cell disease | |||||||||||||
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Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-005229-95 | Sponsor Protocol Number: PBKR03-001 | Start Date*: 2021-08-23 | |||||||||||
Sponsor Name:Passage Bio, Inc. | |||||||||||||
Full Title: A Phase 1/2 Open-Label, Multicenter, Dose Ranging and Confirmatory Study to Assess the Safety, Tolerability and Efficacy of PBKR03 Administered to Pediatric Subjects with Early Infantile Krabbe Dis... | |||||||||||||
Medical condition: Krabbe disease (globoid cell leukodystrophy) is an autosomal recessive lysosomal storage disease (LSD) caused by mutations in the gene encoding the hydrolytic enzyme galactosylceramidase (galactoce... | |||||||||||||
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Population Age: Infants and toddlers, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-002421-38 | Sponsor Protocol Number: D5136C00009 | Start Date*: 2018-06-27 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Randomised, Double-Blind, Parallel-Group, Multicentre, Phase III Study to Evaluate the Effect of Ticagrelor versus Placebo in Reducing the Rate of Vaso-Occlusive Crises in Paediatric Patients wit... | |||||||||||||
Medical condition: Sickle Cell Disease | |||||||||||||
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Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) ES (Prematurely Ended) BE (Completed) GR (Completed) IT (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-005614-29 | Sponsor Protocol Number: CC-486-NSCL-001 | Start Date*: 2015-11-19 | ||||||||||||||||||||||||||||||||||||
Sponsor Name:Celgene Corporation | ||||||||||||||||||||||||||||||||||||||
Full Title: A Phase 2 multicenter, randomized, placebo controlled, double-blind study to assess the safety and efficacy of CC-486 (oral azacitidine) in combination with pembrolizumab (MK-3475) versus pembroliz... | ||||||||||||||||||||||||||||||||||||||
Medical condition: Second-line treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC). | ||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||
Trial protocol: DE (Completed) FR (Ongoing) ES (Completed) GR (Completed) IT (Trial now transitioned) | ||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-002605-62 | Sponsor Protocol Number: BCC1801 | Start Date*: 2018-10-23 | |||||||||||
Sponsor Name:Herlev and Gentofte Hospital | |||||||||||||
Full Title: Phase IIa trial with PD-L1 IO103 vaccination with montanide in patients with basal cell carcinoma. | |||||||||||||
Medical condition: basal cell carcinoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2007-007107-32 | Sponsor Protocol Number: M10-301 | Start Date*: 2009-07-31 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Abbott GmbH & Co. KG | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: A Phase 2 Randomized, Placebo-Controlled, Double-Blind Study of Carboplatin /Paclitaxel in Combination with ABT-869 Versus Carboplatin/Paclitaxel Alone in Subjects with Advanced or Metastatic Non-S... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: Non small cell lung cancer. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: CZ (Completed) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2020-004840-27 | Sponsor Protocol Number: BO42452 | Start Date*: 2021-06-21 | ||||||||||||||||
Sponsor Name:F.Hoffmann-La Roche Ltd | ||||||||||||||||||
Full Title: A PHASE IB RANDOMIZED, PLACEBO-CONTROLLED STUDY EVALUATING THE SAFETY, PHARMACOKINETICS, PHARMACODYNAMICS, AND EFFICACY OF CROVALIMAB FOR THE MANAGEMENT OF ACUTE UNCOMPLICATED VASO-OCCLUSIVE EPISOD... | ||||||||||||||||||
Medical condition: Sickle cell disease (SCD); vaso-occlusive episodes (VOE) in SCD | ||||||||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||
Trial protocol: FR (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing) NL (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-004146-18 | Sponsor Protocol Number: CCR3549 | Start Date*: 2011-11-09 | |||||||||||
Sponsor Name:The Royal Marsden NHS Foundation Trust | |||||||||||||
Full Title: Cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP) versus gemcitabine, cisplatin and methyl prednisolone (GEM-P) in the first line treatment Of T-cell Lymphoma, a multicentre rando... | |||||||||||||
Medical condition: T-cell Lymphoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-001791-19 | Sponsor Protocol Number: G300504 | Start Date*: 2011-09-22 | |||||||||||||||||||||
Sponsor Name:GTx, Inc. | |||||||||||||||||||||||
Full Title: Phase III, Randomized, Double-Blind, Placebo-Controlled Study of the Effect of GTx-024 on Muscle Wasting in Patients with Non-Small Cell Lung Cancer on First Line Platinum Plus a Taxane Chemotherapy | |||||||||||||||||||||||
Medical condition: Cachexia, muscle wasting in patients with Non-Small Cell Lung Cancer | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: HU (Completed) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-001674-34 | Sponsor Protocol Number: AG348-C-020 | Start Date*: 2022-02-17 | |||||||||||
Sponsor Name:AGIOS PHARMACEUTICALS, INC. | |||||||||||||
Full Title: A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Mitapivat in Subjects With Sickle Cell Disease. | |||||||||||||
Medical condition: Sickle Cell Disease | |||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Trial now transitioned) FR (Trial now transitioned) BE (Trial now transitioned) DE (Trial now transitioned) NL (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-005161-20 | Sponsor Protocol Number: SCC01 | Start Date*: 2012-02-14 | |||||||||||
Sponsor Name:University College Dublin Clinical Research Centre | |||||||||||||
Full Title: A Randomised Controlled Double-Blind Trial of Intranasal Fentanyl versus Intravenous Morphine in the Emergency Department Treatment of Severe Painful Sickle Cell Crises in Children | |||||||||||||
Medical condition: Severe Painful Sickle Cell Disease Crises in Children | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-004839-25 | Sponsor Protocol Number: BO42451 | Start Date*: 2021-08-18 | ||||||||||||||||
Sponsor Name:F. HOFFMANN - LA ROCHE LTD. | ||||||||||||||||||
Full Title: A RANDOMIZED DOUBLE-BLIND PHASE IIA STUDY EVALUATING THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CROVALIMAB AS ADJUNCT TREATMENT IN PREVENTION OF VASO-OCCLUSIVE EPISODES (VOE) I... | ||||||||||||||||||
Medical condition: Sickle Cell Disease (SCD); vaso-occlusive episodes in SCD | ||||||||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||
Trial protocol: IT (Trial now transitioned) ES (Ongoing) FR (Trial now transitioned) NL (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-003837-41 | Sponsor Protocol Number: H7T-MC-TADO | Start Date*: 2013-04-15 | |||||||||||
Sponsor Name:Eli Lilly and Company | |||||||||||||
Full Title: A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients with Sickle Cell Disease | |||||||||||||
Medical condition: Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients with Sickle Cell Disease | |||||||||||||
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Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) BE (Completed) NL (Ongoing) IT (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-001838-34 | Sponsor Protocol Number: GBT440-029 | Start Date*: 2019-11-05 | |||||||||||
Sponsor Name:Global Blood Therapeutics, Inc. | |||||||||||||
Full Title: A Phase 2, Open Label, Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Voxelotor in Patients with Sickle Cell Disease | |||||||||||||
Medical condition: Sickle Cell Disease | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: View results |
EudraCT Number: 2013-002597-44 | Sponsor Protocol Number: CFZ004 | Start Date*: 2014-02-10 | |||||||||||
Sponsor Name:Onyx Therapeutics, Inc. | |||||||||||||
Full Title: Phase 1b/2, Multicenter, Open-label Study of Carfilzomib, Carboplatin, and Etoposide in Subjects with Previously Untreated Extensive-stage Small-cell Lung Cancer | |||||||||||||
Medical condition: Untreated extensive stage small cell lung cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) DE (Completed) FR (Completed) HU (Prematurely Ended) | |||||||||||||
Trial results: View results |
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