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Clinical trials for Chondrocyte

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44379   clinical trials with a EudraCT protocol, of which   7391   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    14 result(s) found for: Chondrocyte. Displaying page 1 of 1.
    EudraCT Number: 2015-003584-11 Sponsor Protocol Number: MACT-IBK-2015 Start Date*: 2015-12-11
    Sponsor Name:Medical University Innsbruck
    Full Title: Matrix-associated autologous chrondrocyte transplantation for grade four cartilage lesions of the knee joint - clinical and radiological outcome in correlation to the initial cell count of the cho...
    Medical condition: Cartilage lesion
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10072638 Articular cartilage defect LLT
    18.0 100000004865 10064113 Cartilage allograft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003418-28 Sponsor Protocol Number: CLNA043X2201 Start Date*: 2017-04-18
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, patient and investigator blinded, single dose, Proof of Concept study investigating the safety, tolerability and preliminary efficacy of intra-articular LNA043 in ...
    Medical condition: Acute cartilage injuries
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003481-18 Sponsor Protocol Number: CART.III. Start Date*: 2008-11-17
    Sponsor Name:TBF
    Full Title: PHASE III PROTOCOL COMPARING A MICROFRACTURE TREATMENT TO A CARTIPATCH® CHONDROCYTE GRAFT TREATMENT IN FEMORAL CONDYLE LESIONS
    Medical condition: Femoral condyles single lesion from trauma or osteochondritis dissequans with invalidant signs
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005162-34 Sponsor Protocol Number: clinical_study_protocol Start Date*: 2017-05-19
    Sponsor Name:University Hospital Basel
    Full Title: Randomized, multi-center phase II clinical trial for the regeneration of cartilage lesions in the knee using nasal chondrocyte-based tissue (NTEC) or nasal chondrocyte-based cell (N-CAM)-therapies
    Medical condition: Patients must display 1-2 symptomatic, focal cartilage lesion grade IIIIV (according to the grading by the International Cartilage Repair Society (ICRS)) from 2 to 8 cm2 on the femoral condyle and/...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10072638 Articular cartilage defect LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) HR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000784-16 Sponsor Protocol Number: NCPACI Start Date*: 2016-04-15
    Sponsor Name:Akershus University Hospital
    Full Title: Focal cartilage defects in the knee – A randomized controlled trial comparing Autologous Chondrocyte Implantation with arthroscopic debridement
    Medical condition: Symptomatic focal cartilage defects in the knee
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002507-32 Sponsor Protocol Number: IBD8 Start Date*: 2004-10-11
    Sponsor Name:Royal Hospital For Sick Children, Yorkhill Division
    Full Title: Effect of recombinant growth hormone on growth and chondrocyte dynamics in children with Inflammatory bowel disease (IBD) and growth failure.
    Medical condition: Growth retardation secondary to inflammatory bowel disease in children
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004153-25 Sponsor Protocol Number: JIA6 Start Date*: 2004-12-10
    Sponsor Name:Royal Hospital For Sick Children, Yorkhill Division
    Full Title: Effect of recombinant growth hormone on growth and chondrocyte dynamics in children with juvenile idiopathic arthritis (JIA) and growth failure.
    Medical condition: Growth retardation secondary to juvenile idiopathic arthritis
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023830-22 Sponsor Protocol Number: AAG-G-H-1102 Start Date*: 2012-05-23
    Sponsor Name:TETEC AG
    Full Title: NDisc Study: A Prospective Randomized Multicentre Phase I / II Clinical Trial to Evaluate Safety and Efficacy of NOVOCART® Disc plus Autologous Disc Chondrocyte Transplantation (ADCT) in the Treatm...
    Medical condition: The subject has a disc herniation with back and /or leg pain (radicular pain) and an identification for sequestrectomy according to the guidelines of DGNC and DGOOC.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10022634 Intervertebral disc disorders LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-004120-21 Sponsor Protocol Number: COX1985 Start Date*: 2016-01-22
    Sponsor Name:FUNDACIÓN PÚBLICA ANDALUZA PROGRESO Y SALUD
    Full Title: CLINICAL TRIAL RANDOMIZED, DOUBLE-BLIND CONTROLLED, PHASE III, TO EVALUATE THE USE OF PLATELET RICH PLASMA IN FRONT HYALURONIC ACID IN COXARTHROSIS.
    Medical condition: coxarthrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022891 - Investigations 10058417 Hyaluronic acid PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-016970-33 Sponsor Protocol Number: MACI00809 Start Date*: 2011-03-17
    Sponsor Name:Genzyme Europe BV
    Full Title: An Extension Protocol for Participants of Genzyme-Sponsored Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study of Matrix-Induced Autologous Chondrocyte Implantation (MACI® impl...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. Osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) CZ (Completed) GB (Completed) SE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2006-004817-16 Sponsor Protocol Number: MACI00206 Start Date*: 2008-01-23
    Sponsor Name:Genzyme Europe B.V.
    Full Title: A Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study to Demonstrate the Superiority of Matrix-induced Autologous Chondrocyte Implantation (MACI® implant) versus Arthroscopic Mi...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    13.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) SE (Completed) NL (Completed) PL (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016466-82 Sponsor Protocol Number: cod16HS13 Start Date*: 2010-09-01
    Sponsor Name:CO.DON AG
    Full Title: Prospective, randomised, open label, multicentre Phase-III clinical trial to compare the efficacy and safety of the treatment with the autologous chondrocyte transplantation product co.don chondros...
    Medical condition: Cartilage defects of knee joints, osteochondral defects
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10007713 Cartilage tear in knee LLT
    20.0 100000004848 10007702 Cartilage biopsy LLT
    20.0 100000004859 10003423 Articular cartilage disorder LLT
    20.0 10042613 - Surgical and medical procedures 10052913 Cartilage operation PT
    20.0 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    20.0 100000004859 10007709 Cartilage disorders HLT
    20.0 10042613 - Surgical and medical procedures 10057104 Cartilage repair LLT
    20.1 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    20.0 10042613 - Surgical and medical procedures 10064112 Cartilage graft PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2011-005798-22 Sponsor Protocol Number: AAG-G-H-1202 Start Date*: 2012-11-05
    Sponsor Name:TETEC – Tissue Engineering Technologies – AG
    Full Title: A Clinical Study to Evaluate the Safety and Effectiveness of NOVOCART® 3D plus Compared to Microfracture in the Treatment of Articular Cartilage Defects of the Knee.
    Medical condition: Repair of localized, full-thickness cartilage defects of the femoral condyle (medial, lateral or trochlea) of 2-6cm².
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10052913 Cartilage operation PT
    20.0 100000004863 10007705 Cartilage damage LLT
    20.0 10042613 - Surgical and medical procedures 10057104 Cartilage repair LLT
    20.0 10042613 - Surgical and medical procedures 10064112 Cartilage graft PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) GB (GB - no longer in EU/EEA) CZ (Completed) PL (Completed) HU (Completed) LV (Completed) LT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-016816-20 Sponsor Protocol Number: cod16HS14 Start Date*: 2010-05-24
    Sponsor Name:co.don AG
    Full Title: Prospective, randomised, open label, multicentre Phase II clinical trial to investigate the efficacy and safety of the treatment of large defects (4-10 cm2) with 3 different doses of the autologous...
    Medical condition: Cartilage defects of knee joints, osteochondral defects
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022117 - Injury, poisoning and procedural complications 10007713 Cartilage tear in knee LLT
    18.0 100000004848 10007702 Cartilage biopsy LLT
    18.0 100000004859 10003423 Articular cartilage disorder LLT
    18.0 10042613 - Surgical and medical procedures 10052913 Cartilage operation PT
    18.0 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    18.0 100000004859 10007709 Cartilage disorders HLT
    18.0 10042613 - Surgical and medical procedures 10057104 Cartilage repair LLT
    18.0 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    18.0 10042613 - Surgical and medical procedures 10064112 Cartilage graft PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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