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Clinical trials for Complication

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43865   clinical trials with a EudraCT protocol, of which   7286   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    437 result(s) found for: Complication. Displaying page 1 of 22.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2017-000622-35 Sponsor Protocol Number: 56872 Start Date*: 2017-10-23
    Sponsor Name:Aalborg University Hospital
    Full Title: Different dosis of corticosteroids in mandibular third molar surgery. A randomized, blinded clinical trial assessing pain, trismus, edema, and quality of life outcome measurements.
    Medical condition: The purpose is to investigate the postoperative morbidity after removal of mandibular third molar with different doses of methylprednisolone.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10036278 Postoperative complications NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000505-20 Sponsor Protocol Number: DEXNEF01 Start Date*: 2017-03-28
    Sponsor Name:Eske Kvanner Aasvang
    Full Title: Effect of high versus low dose intravenous dexamethason on complications in the immediate postoperative setting after nephrectomy- a randomized, double-blind, controlled trial
    Medical condition: Post operative complications after open nephrectomy, heminephrectomy and kidney resection (pain, nausea, respiratory/circulatory problems, sedation, quality of sleep)
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004863 10036278 Postoperative complications NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004613-17 Sponsor Protocol Number: 20110912DME1 Start Date*: 2011-12-01
    Sponsor Name:Inst of Ophtalmology Lund University hospital
    Full Title: The effect of intravitreal injections of Lucentis (ranibizumab) on retinal function in diabetic patients with diabetic macular edema and visual impairment
    Medical condition: Diabetic makula edema with visual impairment
    Disease: Version SOC Term Classification Code Term Level
    14.0 10014698 - Endocrine disorders 10012653 Diabetic complications HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001673-32 Sponsor Protocol Number: P150915 Start Date*: 2016-10-19
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: PREVENTION OF POSTOPERATIVE PANCREATIC FISTULA BY SOMATOSTATIN (PREFIPS)
    Medical condition: Patients candidate for pancreatic surgery (pancreaticoduodenectomy or distal pancreatectomy with or without splenectomy).
    Disease: Version SOC Term Classification Code Term Level
    19.0 10017947 - Gastrointestinal disorders 10049192 Pancreatic fistula PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005699-33 Sponsor Protocol Number: 12-179 Start Date*: 2013-07-22
    Sponsor Name:CHU Caen
    Full Title: Etude de la pharmacocinétique de la daptomycine en administration intrapéritonéale chez les patients en dialyse péritonéale présentant une infection péritonéale.
    Medical condition: renal failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022117 - Injury, poisoning and procedural complications 10067594 Peritoneal dialysis complication PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003672-36 Sponsor Protocol Number: 115231,MMR159 Start Date*: 2014-10-09
    Sponsor Name:GlaxoSmithKline Biologicals S.A.
    Full Title: A Phase IIIA, observer-blind, randomized study to evaluate non-inferiority of a second dose of GSK Biologicals’ measles-mumps-rubella vaccine vs. a second dose of Merck & Co., Inc.’s MMR vaccine wh...
    Medical condition: Healthy volunteers (Active immunization against measles, mumps and rubella diseases of healthy subjects, 7 years of age and older).
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10069547 Mumps immunization LLT
    17.1 100000004862 10039276 Rubella with unspecified complications LLT
    17.1 100000004865 10069545 Measles immunization LLT
    17.1 100000004862 10039274 Rubella with other specified complication LLT
    17.1 100000004865 10069564 Rubella immunization LLT
    17.1 100000004862 10028274 Mumps with other specified complication LLT
    17.1 100000004862 10027021 Measles without mention of complication LLT
    17.1 100000004862 10027020 Measles with unspecified complication LLT
    17.1 100000004858 10027022 Measles-like rash LLT
    Population Age: Children, Under 18, Adults Gender: Male, Female
    Trial protocol: SK (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2011-006161-18 Sponsor Protocol Number: 115650 Start Date*: 2014-09-25
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase IIIA, randomized, observer-blind, controlled, multinational study to evaluate the safety and immunogenicity of GSK Biologicals' MMR vaccine (209762) (Priorix®) compared to Merck & Co., Inc....
    Medical condition: Healthy volunteers (Active immunization against measles, mumps and rubella diseases in healthy children, 12 to 15 months of age)
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004865 10069547 Mumps immunization LLT
    18.0 100000004862 10039276 Rubella with unspecified complications LLT
    18.0 100000004862 10039274 Rubella with other specified complication LLT
    18.0 100000004865 10069545 Measles immunization LLT
    18.0 100000004865 10069564 Rubella immunization LLT
    18.0 100000004862 10028276 Mumps with unspecified complication LLT
    18.0 100000004862 10027015 Measles like illness LLT
    18.0 100000004862 10028275 Mumps with other specified complications LLT
    18.0 100000004862 10027021 Measles without mention of complication LLT
    18.0 100000004862 10027020 Measles with unspecified complication LLT
    18.0 100000004858 10027022 Measles-like rash LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: EE (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2018-001382-17 Sponsor Protocol Number: RP1610 Start Date*: 2018-10-30
    Sponsor Name:Alimentiv Inc
    Full Title: Stopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-label, Non-inferiority Trial
    Medical condition: Inactive Crohn’s Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-017085-22 Sponsor Protocol Number: SIMAR Start Date*: 2010-04-27
    Sponsor Name:Technische Universität München
    Full Title: Sugammadex improves muscle function after standard neuromuscular recovery (SIMAR) [Verbesserung der Muskelfunktion durch Sugammadex nach normaler neuromuskulärer Erholung]
    Medical condition: This study wants to test if sugammadex is able to improve postoperative muscle weakness/function and subjective well-being even after complete spontaneous recovery to TOF 0.9 of a rocuronium-induce...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10029315 Neuromuscular blockade PT
    12.0 10057286 Neuromuscular blockade reversal PT
    12.1 10036278 Postoperative complications NOS LLT
    12.1 10052617 Postoperative care LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002652-81 Sponsor Protocol Number: DEXLEV01 Start Date*: 2017-10-17
    Sponsor Name:Eske Kvanner Aasvang
    Full Title: High dose steroids in liver resection – effects on complications and endothelial function in the immediate postoperative phase. A randomized, double-blind, controlled trial
    Medical condition: Complications after liver resections - due to liver disease (mainly primary liver cancer and metastases)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000020453 10036278 Postoperative complications NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-003730-13 Sponsor Protocol Number: OST07/11 Start Date*: 2012-05-22
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Effects of plasma expanders administration in pregnancies complicated by intra uterine growth restriction
    Medical condition: intra uterine growth restriction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10022819 Intrauterine growth retardation LLT
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10061452 Complication of pregnancy PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: View results
    EudraCT Number: 2008-002655-24 Sponsor Protocol Number: SMR-1850/2PX-SP-02 Start Date*: 2008-09-30
    Sponsor Name:SantoSolve A/S
    Full Title: A randomised, double-blind, placebo (vehicle) controlled, parallel group study of the efficacy, safety and tolerability of topical 2PX (strontium chloride hexahydrate) in patients with chronic, mod...
    Medical condition: Post amputation patients (at least 6 months prior to visit 1) with chronic moderate-to-severe lower limb stump pain, defined as average stump pain on a daily basis (≥40 on a 100 mm pain VAS scale) ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023931 Late amputation stump complication LLT
    Population Age: Gender: Male, Female
    Trial protocol: DK (Completed) GB (Prematurely Ended) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001479-22 Sponsor Protocol Number: NCT03021525 Start Date*: 2017-08-04
    Sponsor Name:University Medical Center Hamburg-Eppendorf, Germany
    Full Title: Individualized perioperative hemodynamic goal-directed therapy in major abdominal surgery (iPEGASUS-trial)
    Medical condition: - Hemodynamic Instability - Cardiac Output - High Peroperative Complication
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004205-26 Sponsor Protocol Number: Assente Start Date*: 2006-07-14
    Sponsor Name:OSPEDALE MAGGIORE DI MILANO IRCCS
    Full Title: A Randomised controlled tiral to evaluate the efficacy of low molecular-weight heparin on pregnancy outcome of women with previus pregnancy complication
    Medical condition: To asses wether the treatment with LMWH in Women with previus pregnancy complications and no evidence of anatomical, endocrine, Cromosmal or immunological abnormality result in a 40 reduction in t...
    Disease: Version SOC Term Classification Code Term Level
    6.1 10036585 SOC
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000436-25 Sponsor Protocol Number: RC3600 Start Date*: 2012-12-05
    Sponsor Name:Frederiksberg University Hospital
    Full Title: Randomized, double-blinded and placebo-controlled clinical trial of the Rauvolfia-Citrus decoction in patients with type II diabetes
    Medical condition: Non-insulin dependent diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10012637 Diabetes with peripheral circulatory disorders LLT
    14.1 10027433 - Metabolism and nutrition disorders 10045248 Type II diabetes mellitus with other specified manifestations LLT
    14.1 10027433 - Metabolism and nutrition disorders 10045252 Type II diabetes mellitus without mention of complication LLT
    14.1 10027433 - Metabolism and nutrition disorders 10063624 Type II diabetes mellitus inadequate control LLT
    14.1 10027433 - Metabolism and nutrition disorders 10012640 Diabetes with unspecified complications LLT
    14.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Restarted)
    Trial results: (No results available)
    EudraCT Number: 2012-003132-23 Sponsor Protocol Number: 41354 Start Date*: 2012-11-27
    Sponsor Name:
    Full Title: Local tumescent anaesthesia with ambulatory phlebectomy according to Muller
    Medical condition: Varices according to the CEAP classification
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007313-68 Sponsor Protocol Number: IG0801 Start Date*: 2009-01-07
    Sponsor Name:GRIFOLS ITALIA
    Full Title: A Prospective Randomized Pilot study to evaluate the effect of preoperative antithrombin supplementation on postoperative levels of antithrombin in patients undergoing cardiac surgery with cardiopu...
    Medical condition: Subjects undergoing elective cardiac surgery with Cardio Pulmonar Bypass (CPB) having baseline levels of ATIII activity equal to or higher than 60% and below 100% under all circumstances.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057461 Cardiac procedure complication LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003026-26 Sponsor Protocol Number: ARL - GT 2005 Start Date*: 2008-09-15
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: High-dose chemotherapy with transplantation of gene-modified haematopoietic stem cells for HIV-positive patients with malignant diseases indicating an HSCT
    Medical condition: HIV-positive patients with any malignant disease of the haematopoietic system indicating haematopoietic stem cell transplantation (autologous or allogeneic)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10061624 AIDS related complication LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002243-98 Sponsor Protocol Number: 29702 Start Date*: 2011-09-12
    Sponsor Name:Department of Nephrology, OUH, Odense, DK
    Full Title: The effect of spironolactone on calcineurin inhibitor induced nephrotoxicity
    Medical condition: Kidney graft failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022117 - Injury, poisoning and procedural complications 10010185 Complications of transplanted kidney PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-005441-13 Sponsor Protocol Number: C11-12 Start Date*: 2013-01-03
    Sponsor Name:INSERM
    Full Title: Evaluation of efficacy and safety of autologous MSCs combined to biomaterials to enhance bone healing in patients with delayed consolidation after long bone fracture requiring graft apposition or ...
    Medical condition: Closed or open Gustilo I ans II humerus, tibial or femur diaphyseal or metaphysodiaphyseal fracture.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10017081 Fracture delayed union PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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