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Clinical trials for Constitutional symptoms

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    68 result(s) found for: Constitutional symptoms. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2014-001863-11 Sponsor Protocol Number: EWO-ISO-2014/1 Start Date*: 2014-09-24
    Sponsor Name:Ewopharma AG.
    Full Title: A Phase 4, Randomised, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacy of Isoprinosine® in Comparison With Placebo in Subjects With Confirmed Acute Respiratory Viral Infect...
    Medical condition: Acute Respiratory Viral Infections due to influenza A or B virus, RSV, adenovirus, or parainfluenza virus 1 or 3
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004862 10022005 Influenza viral infections HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2010-021571-88 Sponsor Protocol Number: 920‘135 Start Date*: 2011-11-16
    Sponsor Name:Bioforce AG Roggwil TG
    Full Title: Echinaforce Hotdrink versus Oseltamivir in the Treatment of acute uncomplicated Flu
    Medical condition: acute uncomplicated influenza
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2006-005196-17 Sponsor Protocol Number: BCX1812-211 Start Date*: 2007-01-22
    Sponsor Name:BioCryst Pharmaceuticals, Inc.
    Full Title: A phase II, Multicenter, Randomised, Double-Mask, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Intramuscular Peramivir in Subjects with Uncomplicated Acute Influenza
    Medical condition: Uncomplicated Acute Influenza
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059637 Influenza antibody test LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004885-14 Sponsor Protocol Number: AI452-017 Start Date*: 2012-11-20
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase 3, Randomized, Double-Blind, Controlled Study Evaluating the Efficacy and Safety of Peginterferon Lambda-1a, with and without Daclatasvir, Compared to Peginterferon Alfa-2a, Each in Combina...
    Medical condition: Chronic Hepatitis C
    Disease: Version SOC Term Classification Code Term Level
    16.0 10021881 - Infections and infestations 10008912 Chronic hepatitis C PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) FI (Completed) NL (Completed) IT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2020-001019-26 Sponsor Protocol Number: 202000167 Start Date*: 2021-02-26
    Sponsor Name:University Medical Center Groningen, Department of Rheumatology and Clinical Immunology
    Full Title: [18F]fluor-PEG-folate PET/CT imaging in Giant Cell Arteritis: a pilot study.
    Medical condition: giant cell arteritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-004546-26 Sponsor Protocol Number: VIS410-202 Start Date*: 2017-01-11
    Sponsor Name:Visterra, Inc.
    Full Title: A Phase 2a Double-blind, Placebo-controlled Study to Assess the Safety and Tolerability of a Single Intravenous Dose of VIS410 in Subjects with Uncomplicated Influenza A Infection
    Medical condition: Influenza A infection
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10022002 Influenza A virus infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2007-002527-32 Sponsor Protocol Number: BCX1812-312 Start Date*: 2007-09-05
    Sponsor Name:BioCryst Pharmaceuticals
    Full Title: A Phase III, Multicenter, Ramdomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Intramuscular Peramivir in Subjects with Uncomplicated Acute Influenza
    Medical condition: Uncomplicated acute influenza
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) FI (Prematurely Ended) EE (Prematurely Ended) GB (Prematurely Ended) LV (Prematurely Ended) SE (Prematurely Ended) HU (Prematurely Ended) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003933-14 Sponsor Protocol Number: RM08-3002 Start Date*: 2013-11-04
    Sponsor Name:Romark Laboratories L.C.
    Full Title: A Phase III Randomized Double-Blind Placebo Controlled Trial to Evaluate the Efficacy and Safety of Nitazoxanide and Nitazoxanide plus Oseltamivir in the Treatment of Acute Uncomplicated Influenza
    Medical condition: acute uncomplicated influenza
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003508-11 Sponsor Protocol Number: AI452-033 Start Date*: 2013-08-09
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Double-Blinded, Randomized Control Study Evaluating the Efficacy and Safety of Peginterferon Lambda-1a Compared to Peginterferon alfa-2a, Each in Combination with Ribavirin, in the Treatment of N...
    Medical condition: Chronic Hepatitis C Virus Infection (Genotype 1)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10008912 Chronic hepatitis C PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) PL (Completed)
    Trial results: View results
    EudraCT Number: 2005-003985-40 Sponsor Protocol Number: CZOL446G2422 Start Date*: 2006-01-09
    Sponsor Name:Department of Internal Medicine, University Hospital Gasthuisberg
    Full Title: A prospective multicentre phase II trial of zoledronic acid in patients with myelofibrosis with myeloid metaplasia (MMM)
    Medical condition: myelofibrosis with myeloid metaplasia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) ES (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-004072-19 Sponsor Protocol Number: Acti-INSP-001 Start Date*: 2012-12-28
    Sponsor Name:Vectura GmbH
    Full Title: A randomized, double-blind, parallel group, placebo controlled Phase II study to evaluate the safety and efficacy of inhaled LASAG and Placebo, applied three times daily in adult hospitalized patie...
    Medical condition: Influenza A and B
    Disease: Version SOC Term Classification Code Term Level
    17.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Prematurely Ended) HU (Prematurely Ended) SK (Prematurely Ended) ES (Prematurely Ended) LV (Prematurely Ended) LT (Prematurely Ended) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002822-28 Sponsor Protocol Number: 11034 Start Date*: 2023-06-01
    Sponsor Name:University Medical Center Groningen, Department of Rheumatology and Clinical Immunology
    Full Title: CD8 T cell imaging by positron emission tomography with 89Zr-Df-IAB22M2C in giant cell arteritis and rheumatoid arthritis: a pilot study
    Medical condition: giant cell arteritis and rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015850-39 Sponsor Protocol Number: ADS-TCAD-PO206 Start Date*: 2009-11-12
    Sponsor Name:Adamas Pharmaceuticals, Inc
    Full Title: A Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin with Oseltamivir Versus Oseltamivir to Influenza A Virus Infected I...
    Medical condition: Influenza A Virus
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-018564-17 Sponsor Protocol Number: FAV00A-IIA Start Date*: 2010-12-30
    Sponsor Name:Farmak International Holding GmbH
    Full Title: A Phase II, multicenter, multinational, randomized, double-blinded, placebo-controlled dose-finding study to evaluate the efficacy and safety of carbabenzpyride in the treatment of uncomplicated in...
    Medical condition: (Uncomplicated) Influenza A
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10022002 Influenza A virus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001919-31 Sponsor Protocol Number: DALIAH Start Date*: 2011-09-12
    Sponsor Name:Roskilde sygehus
    Full Title: DALIAH A Danish Study of Low-dose Interferon Alpha Versus Hydroxyurea in the Treatment of Ph-negative Chronic Myeloid Neoplasias - A National Randomized Prospective Study With Focus on Efficacy,...
    Medical condition: Chronic myeloid neoplasms Essential thrombocythemia Polycythemia vera primary myelofibrosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012367-34 Sponsor Protocol Number: BCX1812-301 Start Date*: 2009-11-27
    Sponsor Name:BioCryst Pharmaceuticals, Inc.
    Full Title: A Phase 3, Multicenter, Randomized, Double-Blind, Controlled Study to Evaluate the Efficacy and Safety of Peramivir Administered Intravenously in Addition to Standard of Care Compared to Standard o...
    Medical condition: Influenza
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) NL (Ongoing) LV (Prematurely Ended) CZ (Completed) DE (Prematurely Ended) HU (Completed) GB (Prematurely Ended) SK (Completed) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-004144-28 Sponsor Protocol Number: CCTU0307 Start Date*: 2020-10-23
    Sponsor Name:Cambridge university Hosptials NHS Foundation Trust and University of Cambridge
    Full Title: PROphylaxis for paTiEnts at risk of COVID-19 infecTion
    Medical condition:
    Disease:
    Population Age: Gender:
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-005210-28 Sponsor Protocol Number: MMM02Study Start Date*: 2016-10-11
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Ruxolitinib versus allogeneic stem cell transplantation for patients with myelofibrosis according to donor availability: A prospective phase II trial (MMM 02 study)
    Medical condition: primary myelofibrosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028537 Myelofibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004454-17 Sponsor Protocol Number: ACE-CL-309 Start Date*: 2016-10-24
    Sponsor Name:Acerta Pharma BV
    Full Title: A Randomized, Multicenter, Open-Label, Phase 3 Study of Acalabrutinib (ACP-196) Versus Investigator’s Choice of Either Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in Subjects with Rela...
    Medical condition: Relapsed or Refractory Chronic Lymphocytic Leukemia
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10008978 Chronic lymphocytic leukemia refractory LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Trial now transitioned) SK (Completed) SE (Completed) ES (Ongoing) CZ (Trial now transitioned) AT (Completed) DE (Completed) FR (Completed) BG (Completed) PL (Trial now transitioned) HR (Trial now transitioned) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007587-21 Sponsor Protocol Number: CLL10 Start Date*: 2008-09-05
    Sponsor Name:University of Cologne
    Full Title: Phase III trial of combined immunochemotherapy with Fludarabine, Cyclophosphamide and Rituximab (FCR) versus Bendamustine and Rituximab (BR) in patients with previously untreated chronic lymphocyti...
    Medical condition: patients (age 18 years or older) with chronic lymphocytic leukemia: Stage Binet C or stage Binet B and A requiring treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009310 CLL LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) DK (Completed) CZ (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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