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Clinical trials for Coronary

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,143 result(s) found for: Coronary. Displaying page 1 of 58.
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    EudraCT Number: 2021-006295-17 Sponsor Protocol Number: MedTrace-002 Start Date*: 2022-04-08
    Sponsor Name:MedTrace Pharma
    Full Title: A Phase 3, Multicenter, Open Label Study to Confirm the Diagnostic Potential of Intravenously Administered 15O- H2O to Identify Coronary Artery Disease During Pharmacological Stress and Resting Con...
    Medical condition: Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10006896 CAD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-012206-39 Sponsor Protocol Number: ALX-0081-2.1/09 Start Date*: 2009-08-14
    Sponsor Name:Ablynx
    Full Title: A phase II randomized, open label clinical trial in high risk percutaneous coronary intervention (PCI) patients receiving standard antithrombotic treatment plus either ALX-0081 or GPIIb/IIIa inhibi...
    Medical condition: Thrombotic events associated with percutaneous coronary intervention (PCI) in patients with unstable angina or Non ST-Segment Elevation Myocardial Infarction (NSTEMI), or stable angina with at leas...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011076 Coronary artery atherosclerosis LLT
    9.1 10011078 Coronary artery disease LLT
    9.1 10013210 Disorder coronary artery LLT
    9.1 10063933 Coronary stent thrombosis LLT
    9.1 10065608 Percutaneous coronary intervention LLT
    9.1 10003211 Arteriosclerosis coronary artery LLT
    9.1 10011067 Coronary angiogram abnormal LLT
    9.1 10011093 Coronary atherosclerosis LLT
    9.1 10011099 Coronary disease LLT
    9.1 10051592 Acute coronary syndrome LLT
    9.1 10011076 Coronary artery atherosclerosis LLT
    9.1 10011093 Coronary atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) CZ (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023552-90 Sponsor Protocol Number: BQ123CPBP2010 Start Date*: 2011-05-05
    Sponsor Name:Medizinische Universität Wien, Abteilung für Herzchirurgie
    Full Title: Short-term endothelin A receptor blockade in patients with on-pump coronary artery bypass grafting
    Medical condition: aorto-coronary bypass surgery in patients with coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011077 Coronary artery bypass LLT
    12.1 10011085 Ischaemic coronary artery disorders HLT
    12.1 10011090 Coronary artery surgery LLT
    12.1 10011098 Coronary bypass LLT
    12.1 10049887 Coronary revascularisation LLT
    12.1 10054366 Coronary revascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002726-32 Sponsor Protocol Number: 65/2006/U/Sper Start Date*: 2006-06-20
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: PROtection of coronary Microcirculation by Iloprost: Safety and Efficacy evaluation in PCI
    Medical condition: coronary angioplasty
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050329 Coronary angioplasty LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004779-38 Sponsor Protocol Number: CL3-16257-102 Start Date*: 2013-04-16
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effects of ivabradine on plaque burden, morphology and composition in patients with clinically indicated coronary angiography. A randomised double-blind placebo-controlled international multicentre...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) GB (Prematurely Ended) ES (Prematurely Ended) PT (Prematurely Ended) SK (Prematurely Ended) BE (Prematurely Ended) DE (Completed) CZ (Completed) HU (Prematurely Ended) PL (Prematurely Ended) SE (Prematurely Ended) NO (Prematurely Ended) DK (Prematurely Ended) GR (Prematurely Ended) FR (Completed)
    Trial results: View results
    EudraCT Number: 2005-003013-32 Sponsor Protocol Number: GE IDE No. A01005 Start Date*: 2005-11-08
    Sponsor Name:Deutsches Herzzentrum München
    Full Title: PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, ACTIVE-CONTROLLED; MULTICENTER TRIAL OF BIVALIRUDIN AND UN-FRACTIONATED HEPARIN IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTIONS
    Medical condition: Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011099 Coronary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001983-31 Sponsor Protocol Number: 1842012 Start Date*: 2012-05-25
    Sponsor Name:Juha Hartikainen
    Full Title:
    Medical condition: Coronary artery by-pass surgery patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011076 Coronary artery atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001989-15 Sponsor Protocol Number: HomRate04_2012 Start Date*: 2012-09-17
    Sponsor Name:Universität des Saarlandes
    Full Title: A randomised, placebo controlled, double blind, cross-over, single center clinical Study to investigate the effect of heart rate reduction with ivabradine on endothelial function and vascular stiff...
    Medical condition: Stable coronary heart disease.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10068617 Coronary heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022529-14 Sponsor Protocol Number: WC25501 Start Date*: 2011-02-04
    Sponsor Name:F.Hoffmann-La Roche
    Full Title: A phase III, double-blind, randomized, placebo-controlled, multi-center study evaluating the efficacy and safety of dalcetrapib on lipids, lipoproteins, apolipoproteins and markers of CV risk in pa...
    Medical condition: Coronary Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10068617 Coronary heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) NL (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2009-014690-41 Sponsor Protocol Number: 0908033 Start Date*: 2009-10-09
    Sponsor Name:CHU de Saint-Etienne
    Full Title: Comparison of the protective effect of two cardioplegic solutions Custodiol versus St Thomas on the cardiac metabolism assessed by microdialysis in coronary surgery
    Medical condition: Coronary surgery
    Disease: Version SOC Term Classification Code Term Level
    12.0 10011077 Coronary artery bypass LLT
    12.0 10011090 Coronary artery surgery LLT
    12.0 10068176 Coronary artery bypass graft LLT
    12.0 10011098 Coronary bypass LLT
    12.0 10054366 Coronary revascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017725-19 Sponsor Protocol Number: NC22703 Start Date*: Information not available in EudraCT
    Sponsor Name:F. Hoffmann-La Roche AG
    Full Title: A Phase IIIB multicenter, double-blind, randomized, placebocontrolled study, evaluating the effect of treatment with dalcetrapib 600 mg on Atherosclerotic Disease as measured by I. Coronary Intrava...
    Medical condition: A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001945-42 Sponsor Protocol Number: CRLX030A2203 Start Date*: 2013-09-26
    Sponsor Name:Novartis Pharma Service AG
    Full Title: A multicenter, double blind, randomized, parallel group, placebo-controlled study to evaluate the effects of intravenous serelaxin infusion on micro- and macrovascular function in patients with cor...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-006241-15 Sponsor Protocol Number: GLUTAMICS2 Start Date*: 2012-02-15
    Sponsor Name:Linköping University Hospital
    Full Title: GLUTAmate for Metabolic Intervention in Coronary Surgery II
    Medical condition: Angina CCS class IV treated with coronary artery bypass surgery Coronary artery disease with moderate to severe left ventricular dysfunction treated with coronary artery bypass surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10068176 Coronary artery bypass graft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003492-39 Sponsor Protocol Number: BR1-125 Start Date*: 2008-04-29
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: A phase III study to compare SonoVue® enhanced myocardial echocardiography (MCE) to single photon emission computerized tomography (ECG-GATED SPECT), at rest and at peak of low-dose Dipyridamole s...
    Medical condition: Suspected coronary artery disease (CAD) indicated for stress ECG-gated SPECT and coronary angiography to clarify whether they have a clinical significant coronary stenosis (=70%).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011085 Ischaemic coronary artery disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed) NL (Completed) GB (Completed) IT (Completed) ES (Completed) GR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001959-11 Sponsor Protocol Number: CL3-16257-056 Start Date*: 2005-04-20
    Sponsor Name:Institut de Recherches Internationales
    Full Title: Effects of ivabradine on cardiovascular events in patients with stable coronary artery disease and left ventricular systolic dysfunction. A three-year randomised double-blind placebo-controlled int...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    7.0 10011078 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) FI (Completed) LV (Completed) IT (Completed) CZ (Completed) SK (Completed) GB (Completed) DK (Completed) AT (Completed) SE (Completed) EE (Completed) DE (Completed) IE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-000192-14 Sponsor Protocol Number: TMC-CAN-05-02 Start Date*: 2006-12-21
    Sponsor Name:The Medicines Company
    Full Title: A Clinical Trial Comparing Cangrelor To Clopidogrel In Subjects Who Require Percutaneous Coronary Intervention
    Medical condition: Subjects with coronary atherosclerosis who require PCI (with or without stent).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011093 Coronary atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) ES (Completed) DE (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002427-32 Sponsor Protocol Number: TCA-01-III Start Date*: 2008-07-16
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI FERRARA
    Full Title: Ajuste del tratamiento con tirofibán en pacientes que presentan resistencia a la aspirina o al clopidogrel: 3T/2R Tailoring Treatment with Tirofiban in patients showing Resistance to aspirin and/o...
    Medical condition: Pacientes con enfermedad coronaria que van a someterse a una intervención coronaria percutánea. Patients with coronary disease undergoing percutaneous coronary intervention
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011099 Coronary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-007041-39 Sponsor Protocol Number: IOP-108 Start Date*: 2008-12-18
    Sponsor Name:BRACCO IMAGING
    Full Title: A Phase II Multicenter Randomized Double-Blind Dose-Finding Study of Iopamidol Injection 370 in Multidetector Computed Tomographic Angiography (MDCTA) in Patients with Suspected Coronary Artery Ste...
    Medical condition: Patients who have known or suspected CAD and suspected significant (> 50%) coronary artery stenosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011089 Coronary artery stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-006263-68 Sponsor Protocol Number: GEIDENo.A01207 Start Date*: 2008-07-24
    Sponsor Name:Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen
    Full Title: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF 6 MONTHS VERSUS 12 MONTHS CLOPIDOGREL THERAPY AFTER IMPLANTATION OF A DRUG-ELUTING STENT SAFETY AND EFFICACY OF SIX MONTHS DUAL ANTIPLATELET ...
    Medical condition: Patients with established coronary artery disease on chronic clopidogrel therapy at 6 months after coronary drug eluting stent implantation.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002171-29 Sponsor Protocol Number: GE-IDE-MucT001-14 Start Date*: 2015-07-16
    Sponsor Name:Hospital of the University of Munich, Grosshadern
    Full Title: Intensified Loading with Prasugrel versus Moderate Loading with Clopidogrel in PCI-treated Patients with Biomarker-Negative Angina pectoris.
    Medical condition: Biomarker-negative patients with an indication for percutaneous coronary intervention
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    20.0 10007541 - Cardiac disorders 10074572 Multiple vessel coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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