Clinical trials for Coronary artery bypass surgery

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44335 clinical trials with a EudraCT protocol, of which 7366 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
How to search [pdf]

Advanced Search:

Search tools

Select Country:	Select Age Range:
Select Trial Status:	Select Trial Phase:
Select Gender:
Select Date Range: to
Select Rare Disease:
IMP with orphan designation in the indication
Orphan Designation Number:
Results Status:
Clear advanced search filters

Trials with a EudraCT protocol (182)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

182 result(s) found for: Coronary artery bypass surgery. Displaying page 1 of 10.

EudraCT Number: 2010-023552-90

Sponsor Protocol Number: BQ123CPBP2010

Start Date*: 2011-05-05

Sponsor Name:Medizinische Universität Wien, Abteilung für Herzchirurgie

Full Title: Short-term endothelin A receptor blockade in patients with on-pump coronary artery bypass grafting

Medical condition: aorto-coronary bypass surgery in patients with coronary artery disease

Disease:	Version	SOC Term	Classification Code	Term	Level
	12.1		10011077	Coronary artery bypass	LLT
	12.1		10011085	Ischaemic coronary artery disorders	HLT
	12.1		10011090	Coronary artery surgery	LLT
	12.1		10011098	Coronary bypass	LLT
	12.1		10049887	Coronary revascularisation	LLT
	12.1		10054366	Coronary revascularization	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: AT (Prematurely Ended)

Trial results: View results

EudraCT Number: 2011-006241-15

Sponsor Protocol Number: GLUTAMICS2

Start Date*: 2012-02-15

Sponsor Name:Linköping University Hospital

Full Title: GLUTAmate for Metabolic Intervention in Coronary Surgery II

Medical condition: Angina CCS class IV treated with coronary artery bypass surgery Coronary artery disease with moderate to severe left ventricular dysfunction treated with coronary artery bypass surgery

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10042613 - Surgical and medical procedures	10068176	Coronary artery bypass graft	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Completed)

Trial results: View results

EudraCT Number: 2009-014690-41

Sponsor Protocol Number: 0908033

Start Date*: 2009-10-09

Sponsor Name:CHU de Saint-Etienne

Full Title: Comparison of the protective effect of two cardioplegic solutions Custodiol versus St Thomas on the cardiac metabolism assessed by microdialysis in coronary surgery

Medical condition: Coronary surgery

Disease:	Version	SOC Term	Classification Code	Term	Level
	12.0		10011077	Coronary artery bypass	LLT
	12.0		10011090	Coronary artery surgery	LLT
	12.0		10068176	Coronary artery bypass graft	LLT
	12.0		10011098	Coronary bypass	LLT
	12.0		10054366	Coronary revascularization	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Completed)

Trial results: (No results available)

EudraCT Number: 2013-000998-68

Sponsor Protocol Number: 1.0

Start Date*: 2013-07-02

Sponsor Name:Medizinische Universität Wien, Abteilung für Anästhesie und Intensivmedizin

Full Title: Advanced antibiotic prophylaxis for optimal perioperative protection during coronary artery bypass grafting

Medical condition: antibiotic prophylaxis during cardiac surgery

Disease:	Version	SOC Term	Classification Code	Term	Level
	16.0	10042613 - Surgical and medical procedures	10068176	Coronary artery bypass graft	LLT
	16.0	10042613 - Surgical and medical procedures	10011077	Coronary artery bypass	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: AT (Ongoing)

Trial results: (No results available)

EudraCT Number: 2007-007157-31

Sponsor Protocol Number: Fibro 01/07

Start Date*: 2008-04-16

Sponsor Name:Sahlgrenska Universitetssjukhuset

Full Title: FIBRINOGEN AND BLEEDING AFTER CARDIAC SURGERY

Medical condition: 60 patients undergoing coronary artery bypass surgery

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10011077	Coronary artery bypass	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Completed)

Trial results: (No results available)

EudraCT Number: 2012-003359-12

Sponsor Protocol Number: CCH2012-02

Start Date*: 2015-02-18

Sponsor Name:VU University Medical Center

Full Title: The effect of a high and low protamine-to-heparin dosing on perioperative hemostasis: a randomized clinical trial.

Medical condition: Patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	17.1	100000004865	10006894	CABG	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Ongoing)

Trial results: (No results available)

EudraCT Number: 2016-001529-15

Sponsor Protocol Number: RATIOSTUDY

Start Date*: 2016-10-26

Sponsor Name:AZIENDA SOCIO-SANITARIA TERRITORIALE DI LECCO (ASST LECCO)

Full Title: Randomized Anticoagulation Trial In Opcab HIGH DOSE VERSUS LOW DOSE HEPARINIZATION IN PATIENTS

Medical condition: Off-pump coronary artery bypass grafting (OPCAB) is an established alternative to on-pump coronary artery bypass grafting (CABG), OPCAB, like any other surgical procedure, determines a pro-coagulan...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004865	10011098	Coronary bypass	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2004-004214-16

Sponsor Protocol Number: FS014

Start Date*: 2005-01-19

Sponsor Name:Committee of Management, Common Services Agency T/A Scottish National Blood Transfusion Service

Full Title: A randomised control clinical study to determine whether SNBTS Fibrin Sealant promotes wound healing in patients undergoing cardiac surgery.

Medical condition: In patients undergoing cardiac surgery the saphenous leg vein is used to replace veins used in coronary artery bypass grafts (CABG) surgery.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	7.1		10006894		LLT

Population Age: Adolescents, Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: (No results available)

EudraCT Number: 2004-000140-25

Sponsor Protocol Number: 2003141

Start Date*: 2004-09-08

Sponsor Name:Procter & Gamble Pharmaceuticals

Full Title: A Multicenter, Randomized, Double-Blind, Parallel-group, Placebo-Controlled Study of 2 mg/kg Bolus Plus 24-hour 0.05 mg/kg/hr Infusion Pexelizumab in Patients Undergoing Coronary Artery Bypass Graf...

Medical condition: Prevention of systemic inflammatory response predominantly triggered by the interaction between the patient’s blood and the pump’s artificial surfaces in patients undergoing coronary artery bypass ...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	7.0		10006894		PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: (No results available)

EudraCT Number: 2006-006815-62

Sponsor Protocol Number: NAC/CT/2006.

Start Date*: 2007-05-22

Sponsor Name:University Hospitals of South Manchester NHS Foundation Trust

Full Title: Does N-Acetylcysteine (Parvolex) prophylaxis reduce the incidence of renal impairment after on pump Coronary artery bypass surgery? A prospective randomised controlled trial.

Medical condition: Renal impairment after coronary artery byapass surgery

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10006894	CABG	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Prematurely Ended)

Trial results: View results

EudraCT Number: 2020-005600-19

Sponsor Protocol Number: APHP200072

Start Date*: 2022-06-17

Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS

Full Title: LEvOsimendaN vs. Placebo Before Tricuspid VAlve Surgery in Patients with Right Ventricular Dysfunction

Medical condition:

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004865	10068176	Coronary artery bypass graft	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2012-000232-25

Sponsor Protocol Number: P110138

Start Date*: 2012-06-27

Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)

Full Title:

Medical condition:

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.1	100000004865	10068176	Coronary artery bypass graft	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Completed)

Trial results: (No results available)

EudraCT Number: 2006-004866-14

Sponsor Protocol Number:

Start Date*: 2006-10-09

Sponsor Name:TAYS

Full Title: Aprotiinin keuhkojen toimintaa suojaava vaikutus sydänleikkauksissa

Medical condition: ohitusleikkaus

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	8.1		10011098	Coronary bypass	LLT

Population Age:

Gender: Male, Female

Trial protocol: FI (Completed)

Trial results: (No results available)

EudraCT Number: 2010-020677-17

Sponsor Protocol Number: ALMED-09-C3-026

Start Date*: 2011-11-16

Sponsor Name:Air Liquide Santé International

Full Title: Efficacy and safety of xenon anaesthesia compared to sevoflurane anaesthesia and total intravenous anaesthesia for on-pump coronary artery bypass graft surgery: a randomised, three-arm, single-blin...

Medical condition: General anesthesia for on pump coronary artery bypass surgery

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10042613 - Surgical and medical procedures	10006894	CABG	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Completed) DE (Completed)

Trial results: View results

EudraCT Number: 2008-001135-35

Sponsor Protocol Number: TMC-CAN-08-02

Start Date*: 2010-02-02

Sponsor Name:The Medicines Company

Full Title: Maintenance of platelet inhiBition with cangreloR after dIscontinuation of thienopyriDines in patients undergoing surGEry: The BRIDGE trial

Medical condition: Subjects who present with an acute coronary syndrome.

Disease:	Version	SOC Term	Classification Code	Term	Level
	12.0		10051592	Acute coronary syndrome	LLT
	12.0		10051592	Acute coronary syndrome	PT
	12.0		10006894	CABG	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: CZ (Completed) GB (Completed) AT (Completed) NL (Completed)

Trial results: View results

EudraCT Number: 2010-023839-42

Sponsor Protocol Number: H8O-CY-O027

Start Date*: 2011-04-29

Sponsor Name:General University Hospital in Prague

Full Title: EXEnatide in patients undergoing Coronary artery bypass grafting for improved glUcose conTrol and hemodynamIc ValuEs

Medical condition: Patients with elective coronary artery bypass grafting with LV systolic dysfunction (EF LV ≤ 50%)

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.1	10042613 - Surgical and medical procedures	10011077	Coronary artery bypass	PT
	14.1	10014698 - Endocrine disorders	10012602	Diabetes mellitus (incl subtypes)	HLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: CZ (Completed)

Trial results: (No results available)

EudraCT Number: 2009-018175-14

Sponsor Protocol Number: CL2-16257-088

Start Date*: 2010-04-16

Sponsor Name:Institut de Recherches Internationales Servier

Full Title: Effects of ivabradine IV versus placebo on haemodynamic parameters in patients with a low cardiac output syndrome following planned coronary artery bypass surgery and requiring positive inotropic t...

Medical condition: Coronary Artery Disease patients presenting a low cardiac output syndrome following a planned coronary artery bypass graft and requiring a positive inotropic treatment with dobutamine administered ...

Disease:	Version	SOC Term	Classification Code	Term	Level
	12.1		10068176	Coronary artery bypass graft	LLT
	12.1		10024899	Low cardiac output syndrome	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Completed)

Trial results: View results

EudraCT Number: 2013-005209-30

Sponsor Protocol Number: AGO/2013/013

Start Date*: 2014-01-07

Sponsor Name:Ghent University Hospital

Full Title: The effect of Hydroxyethylstarch 6% 130/0.4 in a balanced electrolyte solution (Volulyte®) compared to gelatine (Geloplasma®) on microvascular reactivity and tissue oxygen saturation during haemodi...

Medical condition: Patients undergoing elective coronary artery bypass grafting surgery.

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.1	100000004863	10059489	Hemodilution	LLT
	14.1	100000004865	10068176	Coronary artery bypass graft	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: BE (Completed)

Trial results: (No results available)

EudraCT Number: 2017-001499-43

Sponsor Protocol Number: TACSI-01

Start Date*: 2017-11-23

Sponsor Name:Sahlgrenska University Hospital

Full Title: Dual antiplatelet therapy with ticagrelor and acetylsalicylic acid (ASA) vs. ASA only after isolated coronary artery bypass grafting in patients with acute coronary syndrome (TACSI trial)

Medical condition: Coronary artery multi-vessel disease and left main stenosis

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004865	10011098	Coronary bypass	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Trial now transitioned) NO (Trial now transitioned) FI (Trial now transitioned) DK (Trial now transitioned) IS (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2011-005526-22

Sponsor Protocol Number: V4

Start Date*: 2012-05-14

Sponsor Name:Medizinische Universität Wien

Full Title: Tissue concentration of cefazolin and linezolid in sternal spongiosa in elective coronary artery bypass grafting: an in-vivo microdialysis study

Medical condition: perioperative antibiotic prophylaxis during coronary artery bypass grafting

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.1	10042613 - Surgical and medical procedures	10036894	Prophylactic antibiotic therapy	LLT
	14.1	10042613 - Surgical and medical procedures	10011077	Coronary artery bypass	PT
	14.1	10042613 - Surgical and medical procedures	10064736	Antibiotic prophylaxis	PT
	14.1	10007541 - Cardiac disorders	10011078	Coronary artery disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: AT (Ongoing)

Trial results: (No results available)

Subscribe to this Search
To subscribe to the RSS feed for this search click here

. This will provide an RSS feed for clinical trials matching your search that have been added or updated in the last 7 days.

Download Options:
Number of Trials to download:

Download Content:

Download Format:


Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.

Query did not match any studies.

For support, Contact us.

The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

European Medicines Agency © 1995-Sat May 10 03:52:04 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands

Austria
Belgium
Bulgaria
Croatia
Cyprus
Czechia
Denmark
Estonia
Finland
France
Germany
Greece
Hungary
Iceland
Ireland
Italy
Latvia
Liechtenstein
Lithuania
Luxembourg
Malta
Netherlands
Norway
Poland
Portugal
Romania
Slovakia
Slovenia
Spain
Sweden
United Kingdom
Outside EU/EEA