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Clinical trials for Cyp2C19

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    41 result(s) found for: Cyp2C19. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2006-001976-19 Sponsor Protocol Number: AKF-371 Start Date*: 2006-06-12
    Sponsor Name:Institut for Sundhedstjenesteforskning, Klinisk Farmakologi, Syddansk Universitet
    Full Title: “Betydningen af CYP2C19 polymorfi for escitaloprams farmakokinetik og farmakodynamik, målt som ændringer i pupildiameter”
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-011543-40 Sponsor Protocol Number: R324 Start Date*: 2009-07-09
    Sponsor Name:Papworth Hospital
    Full Title: Assessment of platelet inhibitory response to clopidogrel when coadministered with a proton pump inhibitor
    Medical condition: To investigate in patients undergoing elective coronary stenting, the interaction between omeprazole, rabeprazole and ranitidine on clopodogrel inhibition of platelet activity in wild type (wt/wt) ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002346-11 Sponsor Protocol Number: IKP102/2006 Start Date*: 2006-08-21
    Sponsor Name:Medical Faculty, Otto-von-Guericke University
    Full Title: Stereoselective pharmacokinetics and CYP2C19-genotyping as outcome predictors of an omeprazole therapy in patients with GERD -- a pilot study (phase IV-study)
    Medical condition: The presented study has to evaluate whether an optimized individual dosage of proton pump inhibitors, adjusted to CYP2C19 genotype, leads to a better pharmakodynamic effect (pH metric acid suppress...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003548-38 Sponsor Protocol Number: 2015-1CR Start Date*: 2015-09-29
    Sponsor Name:Roskilde Hospital
    Full Title: CLOpidogrel response and CYP2C19 Genotype in Ischemic Stroke patients
    Medical condition: Ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-001302-16 Sponsor Protocol Number: IKP103/2008 Start Date*: 2008-06-30
    Sponsor Name:Medical Faculty, Otto-von-Guericke University
    Full Title: Stereoselective pharmacokinetics and CYP2C19-genotyping as outcome predictors of an esomeprazole therapy in patients with GERD -- a pilot study (phase IV-study)
    Medical condition: The presented study has to evaluate whether an optimized individual dosage of proton pump inhibitors, adjusted to CYP2C19 genotype, leads to a better pharmacokinetic effect (pH metric acid suppress...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038263 Reflux oesophagitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016936-11 Sponsor Protocol Number: FAR01-2009 Start Date*: 2011-05-12
    Sponsor Name:Servicio de Farmacia. Hospital Universitario de Bellvitge.
    Full Title: Estudio farmacocinético-farmacodinámico poblacional tras la administración oral o intravenosa de voriconazol en paciente crítico (fase IV)
    Medical condition: paciente crítico en tratamiento con voriconazol oral o endovenoso
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10017537 Fungal lower respiratory tract infections HLT
    13.1 10042613 - Surgical and medical procedures 10066156 Empiric treatment LLT
    13.1 10021881 - Infections and infestations 10061354 Pneumonia fungal PT
    13.1 10022891 - Investigations 10053852 Fungus culture positive LLT
    13.1 10021881 - Infections and infestations 10017533 Fungal infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016443-19 Sponsor Protocol Number: PPG-TOC2009 Start Date*: 2010-01-26
    Sponsor Name:CHU de Poitiers
    Full Title: Etude prospective du rôle prédictif du polymorphisme fonctionnel 5-HTTLPR sur la réponse au traitement par l’escitalopram des patients souffrant d’un trouble obsessionnel compulsif
    Medical condition: obsessive compulsive disorder
    Disease: Version SOC Term Classification Code Term Level
    12.0 10029898 Obsessive-compulsive disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004901-91 Sponsor Protocol Number: P070117 Start Date*: 2008-02-25
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Exploration de l'influence du polymorphisme *2 du gène codant pour le cytochrome 2C19 sur la réponse au clopidogrel chez le jeune coronarien
    Medical condition: Les patients inclus dans cette étude seront issus de la cohorte AFIJI (Architecture de la FIbrine chez les Jeunes coronariens Ischémiques)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011099 Coronary disease PT
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004632-69 Sponsor Protocol Number: P060309 Start Date*: 2006-12-04
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Polymorphismes du gène codant pour le cytochrome 2C19 et réponse au clopidogrel chez le sujet sain
    Medical condition: volontaire sain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10043414 Therapeutic response decreased PT
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024667-40 Sponsor Protocol Number: PGxSTEMI08 Start Date*: 2019-04-23
    Sponsor Name:St. Antonius Hospital
    Full Title: Cost-effectiveness of CYP2C19 guided treatment with antiplatelet drugs in patients with ST-segment-elevation myocardial infarction undergoing immediate percutaneous coronary intervention with stent...
    Medical condition: ST-segment myocardial infarction (STEMI) followed by immediate percutaneous coronary intervention with stent implantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-004913-11 Sponsor Protocol Number: 111075 Start Date*: 2021-02-18
    Sponsor Name:Radboudumc
    Full Title: genotype-guided strategy for antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease’
    Medical condition: Symptomatic or stable pheripheral artery disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004783-38 Sponsor Protocol Number: STH18423 Start Date*: 2015-02-04
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Study of two regimens of TicagrElor compared to clopidogrel in patients undergoing ELective Percutaneous Coronary Intervention (STEEL PCI)
    Medical condition: Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10052086 Coronary arterial stent insertion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-004044-28 Sponsor Protocol Number: AKF-396 Start Date*: 2020-12-18
    Sponsor Name:University of Southern Denmark
    Full Title: Flucloxacillin as an inducer of CYP-enzymes
    Medical condition: Healthy volunteers. (Flucloxacillin is used against infections caused by beta-lactamase-producing organisms) Testing for drug-drug interactions caused by flucloxacillin
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10004035 Bacterial infection due to staphylococcus aureus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-017664-16 Sponsor Protocol Number: 200905-02 Start Date*: 2010-03-22
    Sponsor Name:BIOTRONIK France
    Full Title: GIANT Study - Genotyping Infarct patients to Adjust and Normalize Thienopyridine treatment
    Medical condition: The GIANT trial is dedicated to STEMI patients being treated by a primary PCI (with stent implantation) within the 24 hours following the first pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004239-78 Sponsor Protocol Number: Start Date*: 2005-07-01
    Sponsor Name:Göteborgs Universitet, Institutionen för Invärtesmedicin
    Full Title: Förekomst av syrarelaterade besvär efter utsättning av protonpumpshämmare hos friska frivilliga.
    Medical condition: Studien skall göras på friska försökspersoner
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004470-10 Sponsor Protocol Number: AKF-372 Start Date*: 2008-01-28
    Sponsor Name:Institut for Sundhedstjenesteforskning, Klinisk Farmakologi, Syddansk Universitet
    Full Title: "Effekten af escitalopram på tramdadols farmakokinetik og farmakodynamik"
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002182-29 Sponsor Protocol Number: B1791089 Start Date*: 2016-06-09
    Sponsor Name:Pfizer Inc.
    Full Title: An Open-Label, Multicenter Study To Evaluate The Pharmacokinetics Of Single And Multiple Intravenous Doses Of Pantoprazole In Two Age Cohorts Of Hospitalized Pediatric Subjects 1 To 16 Years Of Age...
    Medical condition: Gastroesophageal Reflux Disease (GERD)
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) DE (Completed) IT (Completed) SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005387-10 Sponsor Protocol Number: ERY-PAO Start Date*: 2013-03-27
    Sponsor Name:Department of hospital Pharmacy, Medical Centre Haaglanden
    Full Title: Effect of Roux-en-Y gstric bypass surgery in morbidly obese patients on Pharmacokinetics of (Acetyl)salicylic acid and Omeprazole.
    Medical condition: Roux-en-Y gastric bypass (RYGB) surgery is a successful treatment for morbid obesity. In this procedure, a small gastric pouch is created. The duodenum is bypassed by connecting the jejunum to this...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003061-38 Sponsor Protocol Number: NL82555.100.22 Start Date*: 2023-05-02
    Sponsor Name:Sint Antonius Ziekenhuis
    Full Title: Genotype-gUIded cLopidogrel monoTherapY (POPular GUILTY)
    Medical condition: Non-ST elevation acute coronary syndrome (coronary artery disease)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006611-29 Sponsor Protocol Number: 80009 Start Date*: 2022-06-28
    Sponsor Name:University Medical Centre Utrecht Department of Vascular Surgery
    Full Title: A randomized placebo-controlled double-blind trial studying the effect of antiplatelet monotherapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel + aspirin) on the occurrence of athero...
    Medical condition: (Chronic) Peripheral (occlusive) arterial disease (PAD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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