Clinical Trials Register

Trials with a EudraCT protocol (108)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

108 result(s) found for: Diabetic Retinopathy AND Type 1 Diabetes AND Diabetes. Displaying page 1 of 6.

EudraCT Number: 2017-003619-20

Sponsor Protocol Number: NN9535-4352

Start Date*: 2019-04-05

Sponsor Name:Novo Nordisk A/S

Full Title: Long-term effects of semaglutide on diabetic retinopathy in subjects with type 2 diabetes

Medical condition: Diabetes Mellitus, Type 2

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004861	10045242	Type II diabetes mellitus	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Trial now transitioned) GB (GB - no longer in EU/EEA) SK (Trial now transitioned) CZ (Trial now transitioned) BG (Trial now transitioned) ES (Ongoing) PT (Trial now transitioned) LV (Trial now transitioned) GR (Trial now transitioned) RO (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2008-002089-74

Sponsor Protocol Number: Matyus-2008/1

Start Date*: 2008-08-15

Sponsor Name:Semmelweis University

Full Title: The investigation of the effect of dihydralazine (Depressan) on macular edema of type 2 diabetes patients and of inhibition of semicarbazide-sensitive amine oxidase (SSAO).

Medical condition: Macular edema in patients with type 2 diabetes.

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10045242	Type II diabetes mellitus	LLT
	9.1		10012675	Diabetic macular retinopathy	LLT
	9.1		10057934	Diabetic macular edema	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: HU (Completed)

Trial results: (No results available)

EudraCT Number: 2008-001454-40

Sponsor Protocol Number: JDRF AWARD#6-2006-1098

Start Date*: 2007-08-02

Sponsor Name:OSPEDALE S. RAFFAELE

Full Title: A multi-step trial towards single donor islet transplantation in type I diabetic patients,using calcineurin inhibotor-free immunosuppression.

Medical condition: tipe I dyabete

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10045228	Type I diabetes mellitus	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: IT (Completed)

Trial results: View results

EudraCT Number: 2012-001208-39

Sponsor Protocol Number: GALILEO242012

Start Date*: 2012-05-14

Sponsor Name:Medizinische Universität Wien, Univ.Klinik für Innere Medizin III, Abt.f.Endokrinologie und Stoffwechsel

Full Title: A new therapeutic approach to prevent acute insulin-mediated complications in type 2 diabetes Subtitle: The effect of the combination of the GLP-1 Analog Liraglutide and Insulin LEvemir® vs. cOnve...

Medical condition: diabetes mellitus type 2, inadequate metabolic control, indication for insulin therapy myocardial lipid accumulation and left-ventricular function, retinal changes, microabluminuria, beta-cell-func...

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.1	10027433 - Metabolism and nutrition disorders	10012607	Diabetes mellitus inadequate control	PT
	14.1	10015919 - Eye disorders	10012689	Diabetic retinopathy	PT
	14.1	10027433 - Metabolism and nutrition disorders	10067585	Type 2 diabetes mellitus	PT
	14.1	10014698 - Endocrine disorders	10012654	Diabetic complications cardiovascular	HLT
	14.1	10007541 - Cardiac disorders	10012647	Diabetic cardiomyopathy	PT
	14.1	10014698 - Endocrine disorders	10012658	Diabetic complications renal	HLT
	14.1	10014698 - Endocrine disorders	10012657	Diabetic complications ophthalmic	HLT
	14.1	10047065 - Vascular disorders	10054044	Diabetic microangiopathy	PT
	14.1	10014698 - Endocrine disorders	10012653	Diabetic complications	HLGT

Population Age: Adults

Gender: Male, Female

Trial protocol: AT (Ongoing)

Trial results: (No results available)

EudraCT Number: 2019-001046-17

Sponsor Protocol Number: SMART-2019

Start Date*: 2019-05-02

Sponsor Name:Uppsala University

Full Title: A multicentre, register-based, randomized, controlled trial comparing dapagliflozin with metformin treatment in early stage type 2 diabetes patients by assessing mortality and macro- and microvascu...

Medical condition: Type 2 Diabetes

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004861	10045242	Type II diabetes mellitus	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2011-000942-39

Sponsor Protocol Number: NL34476.068.11

Start Date*: 2011-06-20

Sponsor Name:CTMM, the Center for Translational Molecular Medicine

Full Title: Effects of thyroid hormone treatment on mitochondrial function, ectopic fat accumulation, insulin sensitivity and brown adipose tissue in type 2 diabetes mellitus.

Medical condition: This trial includes overweight patients with both hypothyroidism and type 2 diabetes.

Disease:	Version	SOC Term	Classification Code	Term	Level
	13.1	10014698 - Endocrine disorders	10021114	Hypothyroidism	PT
	13.1	10027433 - Metabolism and nutrition disorders	10045242	Type II diabetes mellitus	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: NL (Ongoing)

Trial results: (No results available)

EudraCT Number: 2012-005093-54

Sponsor Protocol Number: CV202-010

Start Date*: 2013-05-30

Sponsor Name:Bristol-Myers Squibb International Corporation

Full Title: A Double-Blind, Placebo-Controlled, Randomized, Twostage, Parallel-Group, Adaptive Design Phase 2a Study to Evaluate the Effects of BMS-813160 in Subjects with Type 2 Diabetes Mellitus and Diabetic...

Medical condition: Diabetic kidney disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	17.0	10027433 - Metabolism and nutrition disorders	10067585	Type 2 diabetes mellitus	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DK (Prematurely Ended) FR (Completed)

Trial results: View results

EudraCT Number: 2017-000091-28

Sponsor Protocol Number: EFC15081

Start Date*: 2017-09-04

Sponsor Name:Sanofi-aventis recherche & développement

Full Title: Six-month, Randomized, Open-label, Parallel-group Comparison of SAR341402 to NovoLog®/NovoRapid® in Adult Patients With Diabetes Mellitus Also Using Insulin Glargine, with a 6-month Safety Extensio...

Medical condition: Type 1 diabetes mellitus Type 2 diabetes mellitus

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	10027433 - Metabolism and nutrition disorders	10067585	Type 2 diabetes mellitus	PT
	20.0	10027433 - Metabolism and nutrition disorders	10067584	Type 1 diabetes mellitus	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: HU (Completed) FI (Completed) DE (Completed) PL (Completed)

Trial results: View results

EudraCT Number: 2016-000825-38

Sponsor Protocol Number: M16-04EMPA-EYE

Start Date*: 2016-10-20

Sponsor Name:Hannover Medical School

Full Title: SGLT2-inhibition with Empagliflozin reduces progression of diabetic retinopathy in patients with high risk of diabetic macular edema (The SUPER-Trial)

Medical condition: Patients with type 2 diabetes mellitus

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10027433 - Metabolism and nutrition disorders	10067585	Type 2 diabetes mellitus	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended)

Trial results: View results

EudraCT Number: 2017-000250-19

Sponsor Protocol Number: CADODIAME

Start Date*: 2017-06-13

Sponsor Name:Fundació Hospital Universitari Vall d'Hebron - Institut de Recersa (VHIR)

Full Title: Effect of calcium dobesilate in early stages of diabetic retinopathy

Medical condition: Diabetic retinopathy

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.1	10015919 - Eye disorders	10012689	Diabetic retinopathy	PT

Population Age: Adults

Gender: Male, Female

Trial protocol: ES (Completed)

Trial results: View results

EudraCT Number: 2011-003304-20

Sponsor Protocol Number: OKHN1006

Start Date*: 2012-07-02

Sponsor Name:Moorfields Eye Hospital NHS Foundation Trust

Full Title: Randomised Controlled Trial of Intravitreal therapy with Avastin compared to Observation in Patients with Diabetic Ischaemic Macular Oedema ‘The DIME study’

Medical condition: Ischaemic Diabetic Macular Oedema

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.1	10015919 - Eye disorders	10057934	Diabetic macular edema	LLT
	14.1	10015919 - Eye disorders	10012689	Diabetic retinopathy	PT
	14.1	10015919 - Eye disorders	10012688	Diabetic retinal oedema	PT
	14.1	10015919 - Eye disorders	10012661	Diabetic eye disease	PT
	14.1	10015919 - Eye disorders	10054372	Diabetic retinal edema	LLT
	14.1	10015919 - Eye disorders	10038925	Retinopathy diabetic	LLT
	14.1	10015919 - Eye disorders	10057915	Diabetic macular oedema	LLT
	14.1	10014698 - Endocrine disorders	10012657	Diabetic complications ophthalmic	HLT
	14.1	10015919 - Eye disorders	10054109	Non-proliferative diabetic retinopathy	LLT
	14.1	10014698 - Endocrine disorders	10012653	Diabetic complications	HLGT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Prematurely Ended)

Trial results: View results

EudraCT Number: 2013-000031-27

Sponsor Protocol Number:

Start Date*: 2013-03-20

Sponsor Name:Moorfields Eye Hospital

Full Title: Intravitreal Ranibizumab (Lucentis) Therapy in Patients with Diabetic Ischaemic Macular Oedema (DIME)

Medical condition: Ischaemic Diabetic Macular Oedema

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.1	10015919 - Eye disorders	10057915	Diabetic macular oedema	LLT
	14.1	10015919 - Eye disorders	10012689	Diabetic retinopathy	PT
	14.1	10015919 - Eye disorders	10012688	Diabetic retinal oedema	PT
	14.1	10015919 - Eye disorders	10057934	Diabetic macular edema	LLT
	14.1	10015919 - Eye disorders	10054372	Diabetic retinal edema	LLT
	14.1	10015919 - Eye disorders	10054109	Non-proliferative diabetic retinopathy	LLT
	14.1	10015919 - Eye disorders	10012661	Diabetic eye disease	PT
	14.1	10015919 - Eye disorders	10038925	Retinopathy diabetic	LLT
	14.1	10014698 - Endocrine disorders	10012653	Diabetic complications	HLGT
	14.1	10014698 - Endocrine disorders	10012657	Diabetic complications ophthalmic	HLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Prematurely Ended)

Trial results: View results

EudraCT Number: 2011-000300-18

Sponsor Protocol Number: GN10DI406

Start Date*: 2011-09-08

Sponsor Name:NHS Greater Glasgow and Clyde [...]

Full Title: REducing with MetfOrmin Vascular Adverse Lesions in T1DM (The REMOVAL study)

Medical condition: People with type 1 diabetes with risk factors for cardiovascular disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	100000004861	10045228	Type I diabetes mellitus	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed) NL (Completed) DK (Completed)

Trial results: View results

EudraCT Number: 2012-000452-34

Sponsor Protocol Number: 3004

Start Date*: 2013-11-19

Sponsor Name:Steno Diabetes Center

Full Title: Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy In TYpe 2 diabetic patients with normoalbuminuria

Medical condition: Patients with type 2 diabetes mellitus and normoalbuminuria

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.1	10027433 - Metabolism and nutrition disorders	10067585	Type 2 diabetes mellitus	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DK (Completed) IT (Completed) GB (Completed) NL (Completed) ES (Completed) CZ (Completed) GR (Completed) BE (Completed)

Trial results: View results

EudraCT Number: 2020-002333-15

Sponsor Protocol Number: 20739

Start Date*: 2021-01-15

Sponsor Name:Bayer AG

Full Title: A Phase 2 randomized, placebo-controlled, double-masked proof-of concept study to investigate the efficacy and safety of runcaciguat (BAY 1101042) in patients with moderately severe to severe non-p...

Medical condition: - Non-proliferative diabetic retinopathy: early stage of a medical condition in which damage occurs to the retina due to diabetes mellitus (DM) - DM is characterized by too much sugar in the blood

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.1	100000004853	10054109	Non-proliferative diabetic retinopathy	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended) PL (Completed) CZ (Completed) PT (Completed) NL (Completed) DK (Completed) HU (Prematurely Ended) IT (Prematurely Ended) SK (Completed) BG (Completed) LV (Completed)

Trial results: View results

EudraCT Number: 2008-005032-33

Sponsor Protocol Number: 70242

Start Date*: 2009-01-22

Sponsor Name:Gedeon Richter Plc.

Full Title: Single center, exploratoric, double-blind, placebo controlled study to investigate the efficacy and tolerability of vinpocetine in patients with non-proliferative diabetic retinopathy

Medical condition: Patients with type 2 diabetes mellitus with mild or moderate or severe non-proliferative diabetic retinopathy (NPDR).

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10054109	Non-proliferative diabetic retinopathy	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: HU (Completed)

Trial results: View results

EudraCT Number: 2019-002067-10

Sponsor Protocol Number: BP41321

Start Date*: 2020-07-27

Sponsor Name:F. Hoffmann-La Roche Ltd

Full Title: A randomized, double-masked, 48-week parallel-group, placebo-controlled, proof-of-concept study to investigate the efficacy and safety of RG7774 in patients with Diabetes Mellitus Type 1 or Type 2 ...

Medical condition: Diabetic retinopathy

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.1	10015919 - Eye disorders	10012689	Diabetic retinopathy	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA) SK (Completed) PL (Completed)

Trial results: View results

EudraCT Number: 2010-024062-22

Sponsor Protocol Number: BAIJ1006

Start Date*: 2011-03-22

Sponsor Name:Moorfields Eye Hospital

Full Title: A prospective, randomised controlled trial of Ranibizumab pre-treatment in Diabetic Vitrectomy – a pilot study.

Medical condition: Proliferative diabetic retinopathy

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	13		10036857	Proliferative diabetic retinopathy	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2016-002971-91

Sponsor Protocol Number: 1386-0012

Start Date*: 2017-10-19

Sponsor Name:Boehringer Ingelheim Norway KS

Full Title: A randomized, double-masked, placebo-controlled exploratory study to evaluate safety, tolerability, pharmacodynamics and pharmacokinetics of orally administered BI 1467335 for 12 weeks with a 12...

Medical condition: diabetic retinopathy

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000015258	10054109	Non-proliferative diabetic retinopathy	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NO (Completed) GR (Completed) GB (Completed) ES (Completed) IT (Completed) PT (Completed)

Trial results: View results

EudraCT Number: 2016-002656-24

Sponsor Protocol Number: CTSULENS1

Start Date*: 2018-01-23

Sponsor Name:University of Oxford (Clinical Trials and Research Governance))

Full Title: A randomised placebo-controlled clinical trial of fenofibrate to prevent progression of non-proliferative retinopathy in diabetes

Medical condition: Diabetic retinopathy and diabetic maculopathy

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.1	10015919 - Eye disorders	10012689	Diabetic retinopathy	PT
	20.0	10015919 - Eye disorders	10025425	Maculopathy	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

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Clinical trials for Diabetic Retinopathy AND Type 1 Diabetes AND Diabetes