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Clinical trials for Digestive system disease

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    912 result(s) found for: Digestive system disease. Displaying page 1 of 46.
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    EudraCT Number: 2007-001928-12 Sponsor Protocol Number: 17/2007/U/Sper Start Date*: 2007-04-23
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Contrast enhanced ultrasonography effectiveness in early evaluating of the response to the Sunitinib in the patients with advanced GIST. A pilot study
    Medical condition: Gastrointestinal stromal tumor (GIST)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061174 Gastrointestinal neoplasm LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000065-38 Sponsor Protocol Number: ASL607LIOM01 COMET-GI Start Date*: 2007-02-28
    Sponsor Name:AZIENDA USL 6 LIVORNO ZONA LIVORNESE
    Full Title: METRONOMIC CHEMOTHERAPY WITH URACIL/TEGAFUR (UFT), CYCLOPHOSPHAMIDE (CTX) AND CELECOXIB IN PRETREATED PATIENTS WITH ADVANCED GASTROINTESTINAL MALIGNANCIES: A PILOT CLINICAL STUDY WITH PHARMACOKINET...
    Medical condition: PATIENTS WITH ADVANCED GASTROINTESTINAL MALIGNANCIES
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061174 Gastrointestinal neoplasm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002507-18 Sponsor Protocol Number: CSET2019/2955 Start Date*: 2020-04-10
    Sponsor Name:Gustave Roussy
    Full Title: Efficacy and feasibility of pasireotide to reduce clinically relevant digestive leakage after complete cytoreductive surgery (CRS) plus Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) for perito...
    Medical condition: Primary and secondary peritoneal malignancies
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10068069 Peritoneal carcinomatosis LLT
    20.1 10022891 - Investigations 10080244 Peritoneal cancer index PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004852-39 Sponsor Protocol Number: ORTEGA-PHRCK-2017 Start Date*: 2019-03-12
    Sponsor Name:CHU Dijon Bourgogne
    Full Title: Benefit of a flash dose of corticosteroids in digestive surgical oncology: a randomized, double blind, placebo-controlled trial
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-005891-15 Sponsor Protocol Number: CG104 Start Date*: 2008-05-19
    Sponsor Name:Cogentus Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared with Clopidogrel to Reduce Upper Gastrointestinal Events including Bleeding and Symp...
    Medical condition: Gastrointestinal events including bleeding in patients receiving dual anti-platelet therapy (clopidogrel and aspirin)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018012 Gastrointestinal signs and symptoms HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) DE (Temporarily Halted) CZ (Prematurely Ended) SK (Completed) IT (Prematurely Ended) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002230-41 Sponsor Protocol Number: PPH-LYF02 Start Date*: 2015-06-29
    Sponsor Name:Landspitali University Hospital
    Full Title: Pharmacokinetics of Proton Pump Inhibitors in a random Icelandic Population.
    Medical condition: Gastro Oesophageal Reflux Disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IS (Completed)
    Trial results: View results
    EudraCT Number: 2021-000570-28 Sponsor Protocol Number: IFX001PSHP Start Date*: 2021-11-09
    Sponsor Name:Tampere University Hospital
    Full Title: Accelerated infliximab infusions in inflammatory bowel disease, Phase IV trial
    Medical condition: Inflammatory bowel diseases
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-005136-25 Sponsor Protocol Number: 2011-10-14 Start Date*: 2012-01-12
    Sponsor Name:Matti Eskelinen
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038604 - Reproductive system and breast disorders 10013377 Disorders of uterus, not elsewhere classified LLT
    14.0 10017947 - Gastrointestinal disorders 10017947 Gastrointestinal disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003499-18 Sponsor Protocol Number: PI2022_843_0111 Start Date*: 2023-03-22
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Is there a concordance between the Cellvizio with an intravenous injection of fluorescein and the pathology to determine the microscopic inflammation at the ileal resection margins in Crohn’s ileal...
    Medical condition: Crohn’s ileal disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-004175-31 Sponsor Protocol Number: Prucalopride2017 Start Date*: 2018-04-09
    Sponsor Name:TARGID, KU Leuven
    Full Title: A placebo-controlled trial with prucalopride for the treatment of typical reflux symptoms in patients with gastro-esophageal reflux disease with incomplete proton pump inhibitor response
    Medical condition: refractory gastro-esophageal reflux disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001169-21 Sponsor Protocol Number: S55731 Start Date*: 2015-04-14
    Sponsor Name:Catholic University Leuven
    Full Title: Acid pocket: Determination of position and aspiration
    Medical condition: Gastro-oesophageal reflux disease Healthy volunteers and patients with reflux disease who respond to PPI therapy and who partially respond to PPI therapy will be studied It is known, that after the...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004967-30 Sponsor Protocol Number: RHMMED1596 Start Date*: 2019-04-30
    Sponsor Name:University Hospital Southampton NHS Foundation Trust
    Full Title: IBD Reference and Biosimilar adalimumab CroSS over Study
    Medical condition: Crohn’s disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-000885-36 Sponsor Protocol Number: APPRECIA Start Date*: 2011-12-26
    Sponsor Name:GETECCU
    Full Title: Multicentric, randomized double blind clinical trial and paralell groups to compare Adalimub vs Azatioprina efficacy prevention in Crhon disease post-surgical recurrency after 52 weeks of treatment
    Medical condition: Compare efficay of Adalimub vs Azatioprina to prevent surgical intervention in Chron disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-001638-84 Sponsor Protocol Number: 16-07 Start Date*: 2016-07-08
    Sponsor Name:Meander Medical Center
    Full Title: Thiopurines with Low Dose Allopurinol: a prospective one way cross-over study
    Medical condition: Crohn's disease & Colitis Ulcerosa
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-002026-22 Sponsor Protocol Number: NEOPREMEC Start Date*: 2013-10-24
    Sponsor Name:ErasmusMC
    Full Title: Rectal and oral omeprazole treatment of gastroesophageal reflux in infants with esophageal atresia or congenital diaphragmatic hernia. A pharmacodynamic and pharmacokinetic study
    Medical condition: GORD,
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004851-35 Sponsor Protocol Number: T1040G0013 Start Date*: 2012-12-19
    Sponsor Name:Children´s Hospital, University of Helsinki
    Full Title: Once versus twice daily mesalazine to introduce remission in pediatric ulcerative colitis: a randomized controlled trial
    Medical condition: Ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005059-15 Sponsor Protocol Number: buspironeesostim2011 Start Date*: 2012-02-03
    Sponsor Name:uzleuven
    Full Title: The effect of Buspirone on esophageal sensitivity in healthy volunteers: a randomized, double-blind, placebo-controlled, single-dosing study.
    Medical condition: altered esophageal sensitivity, gastro-esophageal reflux disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001248-67 Sponsor Protocol Number: LIN4113 Start Date*: 2014-01-14
    Sponsor Name:almirall
    Full Title: CLINICAL TRIAL PHASE IIIb to evaluate predictors of response to linaclotide in patients with irritable bowel syndrome and explore the impact on intestinal symptoms
    Medical condition: Irritable bowel syndrome
    Disease: Version SOC Term Classification Code Term Level
    16.1 10017947 - Gastrointestinal disorders 10023003 Irritable bowel syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-018034-11 Sponsor Protocol Number: 2010vanco.psc Start Date*: 2013-04-29
    Sponsor Name:Karolinska Institutet
    Full Title: Open pilot study of treatment with vancomycin to children and adolescents with primary sclerosing cholangitis
    Medical condition: Primary Sclerosing Cholangitis (PSC) is a progressive disease of the biliary system which might lead to increased risk of cholangiocancer. PSC constitutes a common indication for adult liver transp...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004588-11 Sponsor Protocol Number: ABR64005 Start Date*: 2019-09-10
    Sponsor Name:University Maastricht
    Full Title: Control Crohn Safe Trial: Long term efficacy and safety of periodic treatment with adalimumab versus standard step-care for newly diagnosed Crohn's disease.
    Medical condition: The chronic inflammatory bowel disease Crohn's disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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